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  1. effectivehealthcare.ahrq.gov/products/breast-abnormalities-tests/research
    February 09, 2006 - Current Page Topic Timeline Jan. 1, 2005 Topic Initiated Feb. 9, 2006 Systematic Review Effectiveness of Noninvasive Diagnostic Tests for Breast Abnormalities Systematic Review Archived February 9, 2006 Web Version [NLM Site] Download Main Document PDF 1.7 MB Related Files Download Report Appendixes …
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
    September 01, 2014 - Core-needle biopsy, which retrieves a sample of tissue, and open surgical procedures are the most frequently … stereotactic guidance, ultrasound guidance, MRI guidance, other guidance, or freehand), how the biopsy sample … Sixty study arms used vacuum- assisted methods to obtain the biopsy sample; 80 used automated methods … MRI-guided biopsies were evaluated in only six studies with small sample sizes, leading to substantial … average and high risk of breast cancer All biopsy methods Insufficient – Few studies provided within-sample
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/grades-predictive-values_white-paper-2015.pdf
    January 01, 2015 - The objective of our methods project was to use a diverse sample of medical interventions to assess … Results of stratified analyses based on sample size, risk of bias, and magnitude of effect estimates … First, the size of our sample was limited. … Second, how representative our sample is remains unclear. … Influence of trial sample size on treatment effect estimates: meta- epidemiological study.
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay-future_research.pdf
    September 01, 2012 - Studies should have a priori calculation of the sample size needed for determination of the desired … Sample size not an issue, in spite of the relatively low prevalence of PCDs, because the cohorts would … Resource use likely to be moderate; sample size would depend on number of respondents. … The feasibility of such studies generally does not depend on the desired sample size. … Studies should have a priori calculation of the sample size needed for determination of the desired
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/disposition-of-comments-cer-192-anxiety-in-children.pdf
    August 31, 2017 - When there is a sufficient sample of studies we examine disorders separately. … that only includes patients with one of these presenting problems against a sample that includes … “other” comparison as there is not a sufficient sample of homogenous “other interventions” to examine … “other” comparison as there is not a sufficient sample of homogenous “other interventions” to examine … “other” comparison as there is not a sufficient sample of homogenous “other interventions” to examine
  6. effectivehealthcare.ahrq.gov/products/heart-failure-natriuretic-peptide/research-protocol
    December 20, 2011 - Prior to performing the data extraction, a calibration exercise will be conducted using a random sample … The following will also be extracted: blood sample type for BNP measurement (plasma or serum) , assay … showing key study characteristics (i.e. population characteristics, BNP test features, study outcomes,sample … Study Attrition Loss to follow-up (from sample to study population) is not associated with key … characteristics (i.e., the study data adequately represent the sample), sufficient to limit potential
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_executive.pdf
    August 01, 2012 - Followup times varied from 3 months to 13 years, with sample sizes of 40 to 399 patients. … of limitations in study design, including selection/ spectrum bias as well as (in one study) small sample … without adjustments for potential confounders and as C in the other five studies because of their small sample … performance of the SFLC assay varies depending on the type and distribution of PCDs in the study sample … Studies should have an a priori calculation of the sample size needed to determine the desired precision
  8. effectivehealthcare.ahrq.gov/products/depression-chronic-conditions-interventions/research
    August 13, 2012 - Sample sizes ranged from 55 to 1,001, and study duration ranged from 6 to 60 months.
  9. effectivehealthcare.ahrq.gov/products/depression-treatment-ssri/research
    April 26, 2012 - Two studies with limited sample sizes and using risperidone as an augmenting agent showed benefit with
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_executive.pdf
    April 01, 2012 - Similarly, studies where the entire sample were subjects with a cerebrovascular accident, dementias … Inadequate sample size was a factor in many studies. … Adequate sample size was an issue in these studies. … The second trial evaluated a dose escalation of fluoxetine in a small sample, and was suggestive of … A second study, a pilot with small sample size evaluating dose escalation, showed no effect.
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-omega-3_research-protocol.pdf
    September 02, 2016 - This spreadsheet will capture basic intervention, outcome, study design, sample size, and whether results … they meet additional operational eligibility criteria used in the original review (based on minimum sample … intake amounts of n-3 FA), we expect that the primary reason for exclusion will be based on small sample … and study design) but would not have been included in the original report (primarily due to small sample … We quantify such impact as a potential increase in total study population sample size (>20%), a change
  12. effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence.ppt
    January 01, 2010 - Precision Includes sample size, number of studies, and heterogeneity of effect sizes Reporting bias Extent … (II) Precision is the degree of certainty surrounding a result and is determined by sample size, number … Few studies have sufficient sample sizes or duration to adequately assess uncommon or long-term harms … Criteria commonly used to screen OSs for inclusion in CERs: Minimum duration of followup Minimum sample … These criteria may include minimum duration of followup, minimum sample size, a defined threshold for
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence.ppt
    January 01, 2010 - Precision Includes sample size, number of studies, and heterogeneity of effect sizes Reporting bias Extent … (II) Precision is the degree of certainty surrounding a result and is determined by sample size, number … Few studies have sufficient sample sizes or duration to adequately assess uncommon or long-term harms … Criteria commonly used to screen OSs for inclusion in CERs: Minimum duration of followup Minimum sample … These criteria may include minimum duration of followup, minimum sample size, a defined threshold for
  14. effectivehealthcare.ahrq.gov/products/autism-adolescents/research-protocol
    March 29, 2011 - selected this study size based on a previous review of therapies for children with ASD, which used a sample … A cutoff sample size of 20 provides a balance, allowing us to review and comment on adequate literature … In particular, the TEP noted that a sample size of 20 for studies of all types of interventions (e.g. … , medical, behavioral, etc.) takes into account the typically smaller sample sizes in the ASD literature … of publication, study location (e.g., country, city, state) and time period, population description, sample
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-quality-indicator-testing_research.pdf
    April 01, 2010 - ...........................................................................................1 Study Sample … Study Sample Study inclusion criteria differed somewhat between the sites, based on local populations … At JHH/SKCCC, after abstracting 148 medical records, we concluded that we had an adequate sample to … To assess inter-rater reliability (IRR), all nurses at each site abstracted a sample of records (5%, … nurse abstraction to a physician investigator (SMD) gold standard abstraction for the 9 record IRR sample
  16. effectivehealthcare.ahrq.gov/products/continuous-outcomes-correlation/research
    November 19, 2012 - was no apparent association with followup duration, but correlation values were lower with increasing sample
  17. effectivehealthcare.ahrq.gov/products/c-diff-infections/research-protocol
    May 24, 2010 - Overall Do performance measures vary with sample characteristics? … In addition, we will randomly select a 10 percent sample of abstracts determined to be eligible for inclusion … concealment, masking of the treatment status, intention to treat principles, and justification of the sample
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-results-search-strategies-developed-with-without-text-mining-tools.pdf
    March 01, 2021 - • TMTs searches appear less sensitive than UP searches in all but one project, but the small sample … Again, the small sample size precludes significance • TMTs neither affected search evaluation time … The target was set to achieve as large a sample as possible within the project timeframe (1 year). … Because of the small sample size, the analysis was limited to descriptive measures, including means, … Finally, the sample size of librarians was small and all had years of experience, so we were not able
  19. effectivehealthcare.ahrq.gov/products/cancer-anemia-update/research-protocol
    June 16, 2010 - Background and Objectives for the Systematic Review Objective Shekelle et al. 1 reviewed a sampleSample size and extent of missing data will be extracted. … Patients: sampling, exclusion criteria, sample size, baseline characteristics, similarity of groups at … using the following rules: We will use the most complete data sets (i.e., those with the largest sample
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/draft-living-review-plant-chronic-pain-f-risk-of-bias.xlsx
    January 01, 2023 - Risk of bias of cannabis cohort studies Author, Year Did the Study Attempt To Enroll All (or a Random Sample

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