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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause-protocol-130612.pdf
    June 12, 2013 - different target population (the treatment indication being chronic disease prevention in the study sample … studies Exclude Single arm/case series Exclude Case reports Exclude Minimum duration ≥ 12 weeks Sample … studies Include Single arm/case series Exclude Case reports Exclude Minimum duration ≥12 weeks Sample … Include Single arm/case series Exclude Case reports Exclude Minimum duration 5 yearsa 1 yearb Sample … arm/case series Include Case reports (life-threatening events) Include Minimum duration None Sample
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/urinary-incontinence-update_research-protocol.pdf
    June 06, 2017 - Study designs For effectiveness outcomes: Randomized controlled trials (RCTs), with no minimum sample … For harms outcomes: RCTs, with no minimum sample size; nonrandomized longitudinal comparative studies … N = sample size; PICOTS = populations, interventions, comparators, outcomes, timing, and setting; RCT … exposures, and comparators analyzed; outcome definitions; effect modifiers; enrolled and analyzed sample … studies, the 2012 AHRQ review only assessed only study strategies to reduce bias and justification of sample
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-computerized-cds-protocol.pdf
    May 08, 2023 - Depending on the expected volume of literature, the EPC team may opt to have a randomly selected 10% sample … team will decide whether it has enough time and resources to ask a second team member to check a 10% sample … whether it has enough time and resources to ask a second team member to check a randomly selected 10% sample
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/pressure-ulcer-treatment_research-protocol.pdf
    November 08, 2011 - Sample size restrictions will not be set a priori, and case series may be used; however, case studies … for pressure ulcer treatments with a date limit of 1985 to the present (i.e., 2011); Table 1 shows a sampleSample search strategy 1 Pressure Ulcer/dh, dt, nu, rt, rh, su, th, ae, co, in, mo, po, to 2 pressure … or imprecise) We will also estimate publication bias by examining whether studies with smaller sample
  5. effectivehealthcare.ahrq.gov/sites/default/files/outcome-definition-and-measurement-chapter-6.pptx
    January 01, 2013 - frequency and length of followup assessments to be included in the study after initial treatment, and the sample … The study power for a given sample size may be increased when such composite measures are used as compared … This problem can present as a “ceiling” effect, where a larger proportion of the sample reports no disability … Similarly, “floor” effects are seen when the physical activities are too difficult for the sample to … Utility scores are generally first ascertained directly in a sample of people with the condition in question
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_executive.pdf
    September 01, 2013 - Testing for CYP2C19 variants requires a sample of somatic genetic material, usually obtained from a … blood sample or from buccal swabs. … We considered evidence to be sparse if it was from only one study with a small sample size. … The 106 studies had intermediate to large sample sizes: median number of enrolled individuals = 277, … The sample sizes ranged from 21 to more than 2,000 participants, and all 14 studies were relatively
  7. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
    June 01, 2011 - studies of LV mass/ Low (ACEI vs. function, these were dominated by poor-quality studies with ARB); small sample … ACEI or in longitudinal cohort studies, and relatively small sample ARB) sizes for ARBs, the precise … Future research should utilize large databases with sufficient sample sizes to obtain more precise estimates
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-brain-injury_research-protocol.pdf
    December 09, 2009 - After reviewing a sample of relevant articles, the team will design the data collection form and test … publication, study location (e.g., country, city, state) and time period, population description, sample … use established concepts of the quantity of evidence (e.g., numbers of studies, aggregate ending sample
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-research-report-pilot-promote-entry-data-srdr_0.pdf
    October 01, 2019 - ............................................................................................... 2 Sample … Aim 1: Determine the Sources of Flat File Data That Were Recently Submitted by EPCs to SRDR Sample … We restricted the sample size to nine respondents. … Limitation to Survey The small sample size (nine respondents) is an important limitation to the findings … Methods Aim 1: Determine the Sources of Flat File Data That Were Recently Submitted by EPCs to SRDR Sample
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-interventions-maltreatment-child_executive.pdf
    April 01, 2013 - Sample sizes are commonly very small. … For feasibility issues, such families were commonly excluded from a study sample. … Statistical Considerations: Even with concerns about limited sample sizes and attrition, few studies … Childhood abuse and lifetime psychopathology in a community sample. … A longitudinal study of maternal depression and child maltreatment in a national sample of families
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-207-ptsd-disposition-comments.pdf
    May 17, 2018 - We also considered variation in sample characteristics, study characteristics (length and components … A "statistically significant" result, p<.05, merely means that the sample size was large enough to … No matter how small the deviation, there is always a sample size large enough to give 80% power of … In our revision, we do include information about the proportion of the sample with clinical PTSD in … the sample characteristic table for each of our 13 studies that included a portion of participants
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-safety-practices-rapid-protocol.pdf
    September 09, 2022 - A second team member will check a 10% sample of citations to verify that important studies were not … A second team member will check a 10% sample of the full text reviews to verify that important studies
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_disposition-comments.pdf
    June 28, 2013 - Other sample sizes are included in the study characteristics tables provided in Appendix F. … sizes of each study We have added in columns of the sample sizes for all the tables as requested. … We have therefore left off the sample size in the forest plots but have instead included the number … Other sample sizes are included in the study characteristics tables provided in Appendix F. … Other sample sizes are included in the study characteristics tables provided in Appendix F.
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-2-risk-of-reinfection-from-SARSCoV2_0.pdf
    December 31, 2022 - Within a given sample, the “positive” (infected) or “negative” (not infected) cohorts form the denominators … ~85%), but this value should be interpreted in the context of high precision resulting from large sample … reinfection and generally supports our conclusions, though no reinfections were observed, and the sample … Only four of the studies reported on vaccinations in their sample populations, and none reported the … Because prior infection and vaccination both provide strong protection against infection, large sample
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-screening_executive.pdf
    February 01, 2012 - Aliquots—A measured portion of a sample taken for analysis. … Analytic specificity—Ability present in the sample of assay to measure the target substance when potentially … interfering or cross-reacting substances are present in the sample. … assay to detect the presence of hemoglobin in feces that is not visibly apparent in which a fecal sample … allele-specific hybridization reaction to detect K-ras mutations in stool DNA: high prevalence in a large sample
  16. effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-radiation-therapy-bone-metastases.pdf
    August 01, 2022 - Total: 0 Total: 17, from a sample of 200 • RCT: 0 • Pre-post: 15 Clinicaltrials.gov: 2 Question … fractionation, dose constraints, RT techniques in initial radiation Total: 0 Total: 20, from a sample … Because a large number of articles were identified, we reviewed a random sample of 200 titles and abstracts … projected total number of included studies based on the proportion of studies included from the random sample … *These studies were taken from a sample of 200 studies.
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholders-engagement-others_research-2011.pdf
    January 01, 2011 - rationale for recruiting each group (similar to inception cohort) Report methods used to identify, sample
  18. effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update_executive.pdf
    January 01, 2018 - otherwise specified were the most common uses (32% and 37.2%, respectively) for antipsychotics in a sample … d Downgraded for ROB and imprecision because of small sample size, typically < 200 patients in total. … b Downgraded for ROB. c Downgraded for ROB and imprecision because of small sample size, typically < … b Downgraded for ROB and imprecision because of small sample size (typically < 200 patients). 21 … Few studies having small sample sizes reported on major AEs which were often rare outcomes.
  19. S149 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s149.pdf
    October 01, 2007 - The first assumption is that the patients are a random sample drawn from the appropriate reference population … One possibility for E(Yobs K, Z) is to use the sample mean responses within the observed strata of K … This choice can lead to unstable estimates due to small sample sizes, especially for skewed data such … In Table 1, we present the means and medians of the relevant continuous variables for the analytic sample … When clinical trials are not practical, or precluded by the need for a very large sample to detect an
  20. S166 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s166.pdf
    October 01, 2007 - observed between the modified and original indirect comparisons is attributable to both the decreased sample … allows unreasonably high values to be sampled for the variance and should probably not be used when sample … to the wider confi- dence intervals of indirect estimates than of direct estimates (assuming similar sample

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