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  1. effectivehealthcare.ahrq.gov/sites/default/files/considerations-for-statistical-chapter-10.pptx
    January 01, 2013 - Univariate or unadjusted hypothesis testing, such as two-sample t-tests, can be conducted to identify … Unadjusted Analysis Univariate or unadjusted hypothesis testing, such as two-sample t-tests, can be conducted … Complete-case analysis for subjects with no missing data: Can reduce sample size, limiting efficiency … However, an initial limitation with this approach is that sample size is reduced, which affects efficiency
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-screening_disposition-comments.pdf
    February 01, 2012 - In only one FIT is the sample collected with a brush. … Page 21 - See my changes - About 50 percent more patients (641 vs. 426) did not provide an adequate sample … included patients who simply did not perform the test rather than those who submitted an inadequate sample … “Ability present in the sample of assay to measure the target substance when potentially interfering … or cross-reacting substances are present in the sample” We have edited the grammatical error.
  3. effectivehealthcare.ahrq.gov/sites/default/files/sensitivity-analysis-chapter-11.pptx
    January 01, 2013 - These patients should be considered separately where sample size considerations allow. … PMID:19437424. http://www.ncbi.nlm.nih.gov/pubmed/19437424 Sample Graphical Presentation (1 of 2) … Sample Graphical Presentation (1 of 2) This example from Robyn McClelland and colleagues (2008) is a … Sample Graphical Presentation (2 of 2) Plot to assess the strength of unmeasured confounding necessary … between drug use category and confounder; RRCD = association between confounder and disease outcome Sample
  4. effectivehealthcare.ahrq.gov/products/patient-safety-drug-data/abstract
    January 01, 2005 - Data Development for Patient Safety — A Pilot Study using Medicare Part B Drug Data Abstract January 1, 2005 Topic Abstract Medicare administrative claims data offer a valuable informational source for the surveillance of adverse drug events, but there are substantial challenges in exploiting these d…
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-screening_research-protocol.pdf
    May 18, 2011 - In addition, proponents point out that fecal DNA testing requires only a single whole- stool sampleSample Size KQs 1–6: We will not exclude studies based on sample size alone, although it may be considered … source of study funding, study design characteristics, recruitment setting/patient-inclusion criteria, sample … expression analyzed, the assay characteristics and laboratory setting, and the technique used for sample
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/administrative-data-validity_research.pdf
    January 01, 2007 - study using claims data, with few exceptions, investigators should obtain medical records in at least a sample … Investigators then selected a random sample of events and forwarded to CSC to initiate the retrieval … While the sample was sufficiently small (N=7), the PPV is at least 65% and consistent up through and
  7. effectivehealthcare.ahrq.gov/sites/default/files/upenn-final-report-2005-certs-ce-supplement.pdf
    January 01, 2005 - study using claims data, with few exceptions, investigators should obtain medical records in at least a sample … Investigators then selected a random sample of events and forwarded to CSC to initiate the retrieval … While the sample was sufficiently small (N=7), the PPV is at least 65% and consistent up through and
  8. effectivehealthcare.ahrq.gov/products/substance-use-disorders-adolescents/protocol
    October 29, 2018 - Population (all KQs) Age: Adolescents (12–20 years inclusive) Exclude if > 20 percent of study sample … using an Evidence Map structure in which we will gather basic data on each article (e.g., study design, sample … of the interventions and comparators; outcome definitions; effect modifiers; enrolled and analyzed sample … Tables will include descriptions of the study design, sample size, intervention(s), followup duration … evidence per GRADE. 29 Based on further evaluation of the evidence base, we may lower the minimum sample
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/choice-of-mean_white-paper.pdf
    April 01, 2015 - Group #2) Number of Studies (N) Group #1 and Group #2 Total Sample Size (Min-Max) Baseline … Group #2) Number of Studies (N) Group #1 and Group #2 Total Sample Size (Min-Max) Baseline … Group #2) Number of Studies (N) Group #1 and Group #2 Total Sample Size (Min-Max) Baseline … Group #2) Number of Studies (N) Group #1 and Group #2 Total Sample Size (Min-Max) Baseline … Group #2) Number of Studies (N) Group #1 and Group #2 Total Sample Size (Min-Max) Baseline
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_disposition-comments.pdf
    March 01, 2012 - In my own experience when a laboratory moves from testing any sample to only testing loose stools the … “Sample characteristics” should be “patient and stool sample characteristics.” … The descriptions of the sample, groups, and parts of the methods are not identical because there is … We reworded the sample description to clarify that all subjects had recurrent CDI. … The sample consisted of subjects who had recurrent CDI.
  11. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_executive.pdf
    December 01, 2011 - (a) Do the differences in performance measures vary with sample characteristics? KQ 2. … the differences in sensitivity and specificity in stool samples tested within the same lab using the sample … nonstandard intervention for treatment or prevention of CDI be supported by a power analysis, adequate sample … Multicenter studies may be necessary to achieve adequate sample sizes. … How do • Few comparisons are • Comparison of diagnostic • Document stool sample different methods for
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
    November 22, 2011 - The precision of estimates of analytic validity depends on the specific statistic used; generally, a sample … interest were used o Case–control studies o N>10 subjects (per arm, if there are ≥2 arms); smaller sample … trials o Nonrandomized comparative studies o N>10 subjects (per arm, if there are ≥2 arms); smaller sample … because our preliminary searches indicate that non–English- language studies are few and have small sample … those we have used for other CERs and will include elements that address population characteristics, sample
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/dementia-nursing-home-characteristics_disposition-comments.pdf
    October 23, 2012 - I would like to briefly comment on the discussion of detection bias (lack of blinding) and small sample … PwD) manifests itself with such large inter-person or intra person variability that a really large sampleSample size is of course also limited by attrition due to death/decline in this population. … of the interventions/exposures of interest, more studies need to be conducted with larger sample sizes … Sample size and design remain important considerations in terms of validity, but we agree that the
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prosthesis_research-protocol.pdf
    March 16, 2017 - • Any study design • No minimum sample size (except not case reports) • No minimum followup time … adverse effects) Study Design • Any study design, including qualitative studies • No minimum sample … of accessing a LLP Study Design • Any study design, including qualitative studies • No minimum sample … exposures, and comparators analyzed; outcome definitions; effect modifiers; enrolled and analyzed sample … These included descriptions of the study design, sample size, interventions, followup duration, outcomes
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-participant-generated-registries-guide-3rd-ed-addendum-white-paper.pdf
    February 01, 2018 - the Agency for Healthcare Research and Quality (AHRQ).7 While the survey represented a very small sample … About half of the registries in the sample are managed by advocacy organizations, with the others managed … While the sample from the PGR was subject to limitations and biases, the analysis provided rapid proof … T-Test to look at differences in progression rate between self-treating participants and a random sample … Other PGRs may validate the diagnosis for a sample of participants using medical record review or contact
  16. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/patient-participant-generated-registries-guide-3rd-ed-addendum-white-paper.pdf
    February 01, 2018 - the Agency for Healthcare Research and Quality (AHRQ).7 While the survey represented a very small sample … About half of the registries in the sample are managed by advocacy organizations, with the others managed … While the sample from the PGR was subject to limitations and biases, the analysis provided rapid proof … T-Test to look at differences in progression rate between self-treating participants and a random sample … Other PGRs may validate the diagnosis for a sample of participants using medical record review or contact
  17. effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-g.xlsx
    December 18, 2020 - assessments for comparative cohort studies Study Did the study attempt to enroll all (or a random sample
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-1-app-G.xlsx
    January 01, 2023 - Risk of bias of cannabis cohort studies Author, Year Did the Study Attempt To Enroll All (or a Random Sample
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-4-tables-G1-2.xlsx
    January 01, 2022 - Risk of bias of cannabis cohort studies Author, Year Did the Study Attempt To Enroll All (or a Random Sample
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-4-tables-F1-F-2.xlsx
    January 01, 2023 - Risk of bias of cannabis cohort studies Author, Year Did the Study Attempt To Enroll All (or a Random Sample

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