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effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-apbi-breast-cancer.pdf
August 01, 2022 - Evidence map
□ Rapid review
□ Rapid response
□ Expanded topic brief
Key Findings
• From a sample … In that
sample, we found studies relevant to all but KQ4.
4
For KQ1, we found three randomized … Because a large number of articles were identified, we reviewed a random sample of 200 titles
and abstracts … projected total
number of included studies based on the proportion of studies included from the random sample … We took a sample (200 studies) from a total of
878 studies published between 2017 and 2020.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-update_research-protocol.pdf
December 04, 2015 - We do not have a minimum sample size for inclusion, nor do we have a minimum
threshold for extent of … The modified
form will be pilot tested using a sample of the original CER’s studies by all review team … For dichotomous outcomes, we will report
counts or proportions, and sample size, by study arm. … We will assess precision
(precise or imprecise) on the basis of sample size and, if size is adequate … Where there are at least ten studies having variable sample
sizes in a meta-analysis, we will analyze
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/wheelchair-service_technical-brief.pdf
January 01, 2012 - Sample sizes ranged from three to 318 and included individuals of all ages, with most studies
focused … mobility service delivery (continued)
Reference
Study Purpose Population Included Study Design
Sample … Convenience sample
of 132 individuals
participating in the
National Veterans
Wheelchair Games in … Random sample of
mobility assistive
device users (rollators
and manual
wheelchairs) in
Sweden. … Convenience sample
of current patients of
ALS/Muscular
Dystrophy Association
center in Charlotte,
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/suda-final-protocol.pdf
October 02, 2018 - Population (all KQs)
• Age: Adolescents (12 – 20 years inclusive)
o Exclude if > 20 percent of study sample … an Evidence Map structure in
which we will gather basic data on each article (e.g., study design, sample … of the interventions and comparators; outcome definitions; effect
modifiers; enrolled and analyzed sample … Tables will include descriptions of the study design, sample size, intervention(s), followup
duration … evidence
per GRADE.29 Based on further evaluation of the evidence base, we may lower the minimum
sample
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effectivehealthcare.ahrq.gov/sites/default/files/cer-226-labor-dystocia-comments.pdf
May 14, 2020 - main text introduction
General TEP Reviewer #3 a) The excellent details about differences in the sample … the end of this paragraph:
‘Feasibility and ethical challenges with obtaining a large, contemporary
sample … 2020
15
Section
Commentator
& Affiliation
Comment Response
Methods Peer Reviewer #1 Why was sample … Sample size is implicitly
included in the rating of
strength of evidence—
measures of association for
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_research-protocol.pdf
June 11, 2014 - We will not require a minimum sample size for comparative studies addressing Key
Questions 1-4. … For estimating sample size, we used the one-tailed
z-test and the t-test. … and the possibility of an effect size for continuous
outcomes as large as 0.80 or more, the smallest sample … of the numerous possible harm outcomes and study designs,
we were not able to determine a specific sample … After reviewing a sample of relevant articles, the team will test
and revise the screening and data
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_disposition-comments.pdf
August 12, 2016 - Some of the exclusions of
studies on the basis of sample size seem arbitrary: for example, studies of … We have added a small
section, under Minimum
Sample Sizes, to explain our
rationale and to state … In contrast, the minimum sample sizes for RCTs with lipid
and BP outcomes may direct your results in … The sample size was too
small (N<30) in each arm at
1 year followup. … All those that were
not included had already
been rejected (mostly based
on sample size, too-short
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-knee-update-disposition-archived.pdf
May 04, 2017 - We presented the sample
sizes in the narrative
descriptions of the studies,
as well as in the evidence … Noting the total
sample size is not sufficient. … We reincluded all studies
that had been excluded
solely for small sample size,
with the exception … We reincluded all studies
that had been excluded
solely for small sample size,
with the exception … TEP Reviewer
#4
Discussion
/Conclusio
n
Page 67 line 35-27: It appears that trial
sample size
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effectivehealthcare.ahrq.gov/sites/default/files/osteoarthritis-knee-update-disposition.pdf
May 04, 2017 - We presented the sample
sizes in the narrative
descriptions of the studies,
as well as in the evidence … Noting the total
sample size is not sufficient. … We reincluded all studies
that had been excluded
solely for small sample size,
with the exception … We reincluded all studies
that had been excluded
solely for small sample size,
with the exception … TEP Reviewer
#4
Discussion
/Conclusio
n
Page 67 line 35-27: It appears that trial
sample size
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/progestogens-preterm-birth_research-protocol.pdf
June 01, 2010 - and results
• Abstraction of relevant outcomes from data presented in papers must be
possible
• Sample … After reviewing a sample of relevant articles, the methods
lead and the content lead will design three … common elements (e.g., author,
publication year, study location, time period, population description, sample … use
established concepts 1) the quantity of evidence (e.g., numbers of studies, aggregate ending
sample
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-surgical-report-cards.pdf
July 01, 2023 - Depending on the expected
volume of literature, the EPC team may opt to have a randomly selected 10% sample … will
decide whether it has enough time and resources to ask a second team member to
check a 10% sample … whether it has enough time and
resources to ask a second team member to check a randomly selected 10% sample
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs-future_research.pdf
February 01, 2013 - Sample size calculations should ensure
adequate power to test selected predefined hypotheses and take … RCTs with sufficient sample sizes can detect meaningful differences in outcomes because
randomization … Resource use, size, and
duration
RCTs are difficult to recruit to,
require large sample sizes and … Sample sizes will need to be large, and
lost-to-follow-up issues will likely be
significant. … Sample size will need to be large given the
number of treatment options available.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/indirect-comparisons_research-2013.pdf
January 01, 2013 - Table 1 displays the
data from these 54 RCTs, comprising aggregated continuous outcomes (sample mean … That is,
where
population m
is the observed sample m
~ ∆ , ,
ean of the m
ean, is the known … sample variance, and
1, … , ,
easurem
1, …
ents,
, ,
is the num
1,
is the unknown true … For simplicity, we assume that every study has sample size
100 and standard deviation of 2 for every … To sample the partially missing data, we compare the results under missing completely at
random (MCAR
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-term-care-adults_executive.pdf
November 01, 2012 - NH residents or Medicare home health recipients); no
relevant comparison; no relevant settings or sample … We abstracted data based on study design; location (the
United States or international); sample populations
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-6-protocol.pdf
December 07, 2024 - Diagnosis of acute stress disorder
• Studies that do not specify criteria used to
diagnose PTSD
• Sample … and determined to meet inclusion criteria, we will abstract study
design, year, setting, country, sample … Characteristics of
included studies, such as number of publications by year, study sample size, proportion … Study Comments
15
Sample Characteristics
1. N Randomized
2. … Duration of Symptoms/Diagnosis Sample Characteristics: Standard Deviation
15.
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/cervical-degenerative-protocol.pdf
January 12, 2022 - Appendix A contains our sample MEDLINE® search strategy which will be
adapted to search the other databases … will conduct appropriate statistical tests (e.g., funnel
plots, statistical tests for Egger’s small sample … This may be based on sample size sufficiency and number of
events. … When quantitative synthesis is not possible, sample size
and assessment of variance within individual … Sample Search Strategies: Cervical Degenerative Disease Treatment
Strategies will be adapted for databases
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/autoimmune-disease-rapid-research.pdf
November 01, 2024 - country, autoimmune disease
and associated medication for treatment
• Study design: study design, sample … included primary studies
Study
Type
Author
Year
Country
Study Design
Followup Length
Sample … 1, Primary Studies
21
Study
Type
Author
Year
Country
Study Design
Followup Length
Sample … 1, Primary Studies
22
Study
Type
Author
Year
Country
Study Design
Followup Length
Sample … 1, Primary Studies
23
Study
Type
Author
Year
Country
Study Design
Followup Length
Sample
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-prognostic.ppt
June 01, 2012 - Did the sample represent patients who would be tested in clinical practice? … Were the results externally validated using an independent sample or internally validated using bootstrap … Were previously established prognostic tests that were used as comparators fitted to the sample data … term=17182986
Fitting a new prognostic test to the sample data (test development sample) by using … Sample Reclassification Table Based on Predicted Outcome Probabilities
Step 4: Extracting Statistics
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-prognostic.ppt
June 01, 2012 - Did the sample represent patients who would be tested in clinical practice? … Were the results externally validated using an independent sample or internally validated using bootstrap … Were previously established prognostic tests that were used as comparators fitted to the sample data … term=17182986
Fitting a new prognostic test to the sample data (test development sample) by using … Sample Reclassification Table Based on Predicted Outcome Probabilities
Step 4: Extracting Statistics
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive-2016.pdf
January 01, 2016 - differences in skill levels
of the practitioners drawing or analyzing the samples, or
differences in sample … or end-stage renal disease patients (12); titles with no
abstracts (based on a survey of a random sample … examined
the effect of the type of practitioner performing fluid
aspiration on the ability to obtain a sample … Insufficient No conclusion possible
Duration of current flare Insufficient No conclusion possible
MSU sample … The accuracy of
methods for urate crystal detection in synovial fluid and the
effect of sample handling