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effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-genetic.ppt
June 01, 2012 - Factors
Obtaining, preserving, and storing samples before analysis
Analytic Factors
Type of assay, sample … Analytic variables include the type of assay chosen and its reliability, the type of sample, the methods … term=12181099
DNA-Based Assays
Analyze the DNA itself
Use a variety of sample sources (e.g., blood … A variety of DNA sample sources are available, such as blood, cheek swabs, and hair. … term=19141767
Sample Size Calculations
It is important to assess whether sample size calculations
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-infertility_research.pdf
June 01, 2017 - other trial registration numbers and
then trial characteristics, including: condition, intervention, sample … Two trials with a
combined sample size of 340 patients were completed more than 3 years ago, indicating … Three
studies did not report the sample size in CT.gov and thus were classified as discrepant. … Both trials were applicable to KQ 1 and had a combined
sample size of 340 patients.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
July 13, 2011 - head-to-
head comparisons: double-blind, placebo-controlled RCTs
Minimum study duration
6 weeks
Sample … fair quality, controlled observational studies
Minimum study duration
For all studies: 3 months
Sample … studies: 3 months
Study population
Adult inpatients and outpatients with recurrent depression
Sample … inpatients and outpatients with major depressive disorder,
dysthymia, or subsyndromal depression
Sample
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_disposition-comments.pdf
September 28, 2015 - Peer Reviewer 1 Methods It is not clear whether the mean differences were
weighted by sample size and … If not, then small and large studies
Studies were weighted by sample size and variance. … T2DM based on
whether the majority of the sample (>75%) were of one
disease is somewhat questionable … Peer Reviewer 4 Results Table 10, I would suggest to adding the sample size in
each node. … We have added the sample sizes.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-patient-family-engagement.pdf
July 01, 2023 - Depending on the expected volume of literature, the EPC team may opt to have a randomly
selected 10% sample … team will decide whether it has enough time and resources to ask a second
team member to check a 10% sample … whether it has enough time and resources to ask a second
team member to check a randomly selected 10% sample
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/lumbar-fusion-protocol.pdf
June 20, 2024 - This
may be based on sample size sufficiency and number of events. … When
quantitative synthesis is not possible, sample size and assessment of variance
within individual … If sufficient numbers of
RCTs (>10) are available to evaluate small sample effects, quantitative funnel … Sample Search Strategies: Lumbar Fusion
Strategies will be adapted for databases to be searched. … Sample Search Strategies: Lumbar Fusion
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effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-evidence-summary.pdf
March 01, 2021 - interventions in the outpatient and inpatient settings suffers
from too few RCTs with too small of sample … Filling the gaps in the evidence will require RCTs with sample sizes large
enough to evaluate important
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-254-rural-telehealth-app-e.xlsx
January 01, 2021 - Random Sample or Consecutive/All Patients Meeting Inclusion Criteria? … Random Sample or Consecutive/All Patients Meeting Inclusion Criteria?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_executive.pdf
November 01, 2012 - For studies of diagnostic accuracy, we created 2x2 tables
from information provided (usually sample … whether it evaluated a representative spectrum
of patients; whether it enrolled a random or consecutive
sample … potential negative psychological and social effects, but are difficult to
interpret due to small sample … and not screened for HCV infection
would provide the most direct evidence, but would
require large sample
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0255_06-25-2010.pdf
January 01, 2010 - identified that comprehensively examine the role of all possible intravascular
techniques with a literature sample
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
May 24, 2010 - Do performance measures vary with sample characteristics? … In addition, we will randomly select a 10 percent sample of abstracts determined to be eligible
for … Source: www.effectivehealthcare.ahrq.gov
Published Online: May 24, 2010
justification of the sample
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-emergency_research-protocol.pdf
July 18, 2011 - care center for
treatment of severe headache within the previous 12 months.
8
In a representative sample … We will pre-test this form on a sample of studies. … A sample of studies will be used to pilot both
tools. … author, date of publication, study design, setting, treatment groups,
inclusion/exclusion criteria, sample … interventions compared with placebo, as well as estimates of which interventions are the best.
26
A burn-in sample
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia_research.pdf
January 01, 2013 - this viewpoint is not universally accepted in the setting of CKD.2 Moreover,
taking a bone marrow sample … The sample size calculation becomes more tedious to do when the same
subject undergoes multiple tests … The sample size calculation becomes more tedious when the same subject
undergoes multiple tests, as … is important to control for these confounding factors in future research, which will
require large sample … Power and sample size calculation of
comparative diagnostic accuracy studies
with multiple correlated
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-executive.pdf
December 01, 2009 - Open surgical biopsy involves removing a sample of
tissue from the suspicious area through a surgical … After the tissue sample is removed, the
incision is closed with sutures.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-disease-medicine_research-protocol.pdf
November 01, 2010 - We will exclude RCT or CCT
with a sample size of less than 100 participants (total enrollment) and those … We believe
that studies with smaller sample sizes and/or shorter follow-up duration would have
extremely … We will exclude studies with a sample
size of less than 50 participants (total enrollment) and those … We will exclude studies with a sample size less than 50
participants (total enrollment across groups … We will randomly select a 10%
sample of all abstracts for repeat review by one of the physician project
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bariatric-surgery_research.pdf
June 01, 2010 - We then tested the model in the second half of the sample. … We examined the model by applying
it to a large sample of enrollees in 5 participating BCBS plans using … The final model had an ROC of 0.714
in the validation sample. … Comparison of the performance of different models in the validation sample (N=35,528)
Risk Model Based … Screening characteristics of the selected propensity model in the validation sample
Percentile of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/joint-replacement-disposition-comments.pdf
November 03, 2021 - significant benefit when
two active forms of treatment are compared (compounded by the issues of small sample
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-kidney-disease-anemia-2011_disposition-comments.pdf
January 01, 2011 - LDOs and most MDOs and
SDOs use central labs which entail a significant time
delay between blood sample … These
machines actually run a CHr on every sample but only
report the result if the CHr is ordered … We mentioned the sample storage
issue in “Applicability and Implications for Clinical and Policy
Decisionmaking
-
effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1512.pdf
December 01, 2015 - The
Cytosponge™ Cell Collection Device is intended to capture a sample of esophageal cells for
laboratory … Intervention: The Cytosponge™ Cell Collection Device is intended to capture a sample of
esophageal
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/prevent-hai-protocol.pdf
April 16, 2024 - Appendix 1 presents a
sample search strategy.
3
Literature screening will be performed using … Sample Search Strategy
Embase and MEDLINE in Embase.com Syntax
Line # Description Search String
#1 … of
knowledge*' OR 'web of science')) OR (systematic*
NEAR/3 review*)):ti,ab)
#15 RCTs ('random sample