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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-protein-intake-protocol-amendment.pdf
    November 28, 2023 - during screening, we will “tag” studies in PICO portal (using certain identifiers, such as small sample … size for metabolic Smaller sample sizes may be observed for highly controlled metabolic 14 … Thus, studies performed in this population will also be included regardless of sample size. 11/ … Smaller sample sizes may be observed for highly controlled metabolic studies due to the level of … Thus, studies performed in this population will also be included regardless of sample size. 11/
  2. effectivehealthcare.ahrq.gov/sites/default/files/Evidence%20Summary_2.pdf
    May 01, 2020 - versus control: Evidence summary in women with unspecified parity Category Outcome Study Design (Sample … Moderate (Imprecise) 11 Category Outcome Study Design (Sample Size) Conclusion SOE (Rationale … versus control: Evidence summary in women with unspecified parity Category Outcome Study Design (Sample … Ambulation versus control: Evidence summary in nulliparous women Category Outcome Study Design (Sample … Feasibility and ethical challenges with obtaining a large, contemporary sample of women laboring with
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveill-report-1.xlsx
    September 30, 2015 - controlled trials Author, Year Study Design Duration Setting Country Eligibility Criteria Interventions Sample … Oral methadone (30 to 60 mg daily) (9 assigned, 6 f/u) Overall sample Mean age: 41 years Female sex: … B (unmatched sample) Mean age (SD): 55.6 (13.22) vs. 58.2 (12.82) years Female sex: 9.88% vs. 9.49% … ); 38,716 (matched sample) Visit counts for physical therapy, pain clinics, chiropractic care, primary … HR 1.19 (95% CI 1.06 to 1.35) Insurance Fair Salkar, 2021 Case-control, Medicare 5% National Sample
  4. effectivehealthcare.ahrq.gov/sites/default/files/study-size-planning-chapter-9.pptx
    January 01, 2013 - The tyranny of power: is there a better way to calculate sample size? BMJ 2009 Oct 6;339:b3985. … Investigators should also consider other cases whereby the sample size may be reduced—such as loss to … Report the statistical power or type II error level (for study size calculations) or the assumed sample … Report the details of the sample size formulas and calculations including correction for loss to followup … Examples include Stata, Confidence Interval Analysis, and Power Analysis and Sample Size (PASS).
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-frameworks.ppt
    June 01, 2012 - Sample Replacement Test Project: FFDM Versus SFM (2 of 4) Samson D, Schoelles KM. … Sample Replacement Test Project: FFDM Versus SFM (4 of 4) Samson D, Schoelles KM. … Sample Replacement Test Project: FFDM Versus SFM (4 of 4) To summarize the sample replacement test project … Sample Add-on Test Project: HER2 Gene Amplification Assay (2 of 4) Samson D, Schoelles KM. … Sample Triage Test Project: Positron Emission Tomography (2 of 4) Samson D, Schoelles KM.
  6. effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-frameworks.ppt
    June 01, 2012 - Sample Replacement Test Project: FFDM Versus SFM (2 of 4) Samson D, Schoelles KM. … Sample Replacement Test Project: FFDM Versus SFM (4 of 4) Samson D, Schoelles KM. … Sample Replacement Test Project: FFDM Versus SFM (4 of 4) To summarize the sample replacement test project … Sample Add-on Test Project: HER2 Gene Amplification Assay (2 of 4) Samson D, Schoelles KM. … Sample Triage Test Project: Positron Emission Tomography (2 of 4) Samson D, Schoelles KM.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/indirect-comparisons_research.pdf
    March 01, 2013 - Pfizer Inc C-7 Reference Study, Sample Inclusion Criteria Exclusion Criteria Active Control … C-8 Reference Study, Sample Inclusion Criteria Exclusion Criteria Active Control Sponsorship such … Herschorn, 201028 Study:RCT Sample:1712 Men and women aged ≥18 years, with symptoms of OAB … C-29 Reference Study, Sample Inclusion Criteria Exclusion Criteria Active Control Sponsorship of … C-32 Reference Study, Sample Inclusion Criteria Exclusion Criteria Active Control Sponsorship of
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-2.xlsx
    September 30, 2015 - controlled trials Author, Year Study Design Duration Setting Country Eligibility Criteria Interventions Sample … Oral methadone (30 to 60 mg daily) (9 assigned, 6 f/u) Overall sample Mean age: 41 years Female sex: … B (unmatched sample) Mean age (SD): 55.6 (13.22) vs. 58.2 (12.82) years Female sex: 9.88% vs. 9.49% … ); 38,716 (matched sample) Visit counts for physical therapy, pain clinics, chiropractic care, primary … HR 1.19 (95% CI 1.06 to 1.35) Insurance Fair Salkar, 2021 Case-control, Medicare 5% National Sample
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-future_research.pdf
    April 01, 2013 - Again, blinding and sample size are key considerations. … This should be considered when calculating sample size. … Again, blinding and sample size are key considerations. … A sample with diverse disease characteristics will be necessary. … This should be considered when calculating sample size.
  10. S81 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s81.pdf
    October 01, 2007 - Subjects: A random sample of 3987 admissions drawn from all 41 Utah acute-care hospitals in 2001 and … If the combined accuracy of jackknife classifications was at least as good as the whole-sample model, … We expect increased stability with adequate sample sizes. … Moreover, the sensitivity analysis of a small sample of admissions at each hospital demonstrated wide … At the time of this writing, however, there was only 1 report of a validated PSI using a cohort sample
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/congestive-heart-failure-medicines_research.pdf
    March 01, 2010 - However, the effectiveness of H-ISDN in a community sample of African-Americans and other racial/ethnic … We excluded 366,249 patients (62% of the total) and took a random sample of 20% of Whites (excluding … Our sample was >98% male, limiting the generalizability of our findings to women. … This large sample allowed us to evaluate outcomes in multiple subgroups. … WITH ADEQUATE SAMPLE SIZE (N = 223,354) HISPANIC (N = 7,731) AFRICAN-AMERICAN (N = 32,611) WHITE
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_research-protocol.pdf
    March 09, 2010 - Because JIA is rare, assembling a large sample size is challenging. … Therefore, we will not restrict studies based on sample size alone. … ] • Sample consists of children 18 years of age or younger. … If the study includes adults, at least 80 percent of the sample will be children or the outcomes must … • Sample consists of children 18 years of age or younger.
  13. Slide 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/cf_deliberativemethodswebinar_recruiting.pdf
    May 29, 2025 - Slide 1 Recruiting/Selecting Participants Susan Dorr Goold, MD, MHSA, MA Professor of Internal Medicine and Health Management and Policy University of Michigan 1 Alternatives to Random Sampling • Substantive representation – Based on extent to which groups affected by decision at issue …
  14. effectivehealthcare.ahrq.gov/products/grant-manuscripts/graphical-augmentations-abstract
  15. S38 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s38.pdf
    October 01, 2007 - of the anticipated design effect for a proposed cluster-randomized trial and its impli- cations for sample … From the parallel perspective of the necessary sample size to detect a prespeci- fied effect with given … Usually, assuming the same total number of patients in a given study, the variance of the sample mean … In many settings, one can use standard approaches for estimating sample size, assuming no clustering, … UNBALANCED COVARIATES AND BALANCING SCORES With reasonable sample sizes, randomization will tend to
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-bias_methods.pdf
    July 01, 2012 - aspects of data analysis, applicability, whether ethics approval is specified, and 5-2 whether sample … Selection bias The selection process determines the composition of the study sample. … Partial verification bias Only a selected sample of patients who underwent the index test is verified … Did the whole sample or a random selection of the sample receive verification using a reference … YES: All relatives that the proband identifies/reports upon represent the whole sample of relatives.
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-future_research.pdf
    February 01, 2012 - Approximate Sample Size Required Per Group for Comparisons of Two Proportions . 23 Table 7. … We also performed sample power analyses to help identify pragmatic barriers of the potential designs … Sample Size Requirements This section provides a simple framework for thinking about the sample size … of 14 (the sample size listed for an effect size of 0.80 and one sample). … Java Applets for power and sample size [Computer software]. 2006-9.
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-appendix-c-prepub-final.xlsx
    January 01, 2025 - A nonconsecutive convenience sample was used. … The details all focus on the split sample (development sample and validation sample) rather than on the … external validation sample. … The details all focus on the split sample (development sample and validation sample) rather than on the … external validation sample.
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-final-app-c.xlsx
    January 01, 2025 - A nonconsecutive convenience sample was used. … The details all focus on the split sample (development sample and validation sample) rather than on the … external validation sample. … The details all focus on the split sample (development sample and validation sample) rather than on the … external validation sample.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-interventions-maltreatment-child_disposition-comments.pdf
    April 15, 2013 - The authors build a strong case across the manuscript for the limitations of the data (from small sample … myself tend to reduce the persuasiveness of intervention restudies for the following reasons: small sample … We can only estimate the effect of treatment in a certain population (represented by the sample) for … This proclivity is particularly misleading when the size of the sample is small: Twersky and Kahneman … The authors do identify one of the major limitation of small sample sizes in that it is difficult to

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