-
effectivehealthcare.ahrq.gov/sites/default/files/adhd_disposition-comments.pdf
October 01, 2011 - Also, the sample size should be
mentioned, the denominator for the 44 CVAs and 21 TIAs. … Atomoxetine's
sponsor reported that its safety sample was well over 3,000 subjects. … However, it is
becoming clearer now from analyses done in the 2007 Swanson papers
on the MTA Sample … The key paper by Molina et al in 2009 on the 8 year follow up of the MTA
sample is also missing. … been helpful would have been to include the work of Ron Kessler
using the US National Comorbidity Sample
-
effectivehealthcare.ahrq.gov/products/ptsd-adult-treatment-update/research-protocol
May 24, 2017 - For KQ 4, we have chosen a sample size cutoff of 500 for prospective cohort studies and case-control … nonrandomized controlled trials, prospective cohort studies with an eligible comparison group and a sample … size of at least 500, a case-control studies with a sample size of at least 500 a
All other designs … and studies using included designs that do not meet the sample size criterion
Language
Studies published … We will reassess risk of bias in a random sample of 10 studies included in the prior review that continue
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-chronic-conditions-interventions_executive.pdf
August 01, 2012 - Description of Included Studies
In the 10 included trials, sample sizes ranged from 55 to
1,001, and … Summary of collaborative care intervention trials
Author/Trial Name
Disease
Sample Size
Quality
Ratinga … Summary of collaborative care intervention trials (continued)
Author/Trial Name
Disease
Sample Size … Summary of collaborative care intervention trials (continued)
Author/Trial Name
Disease
Sample Size … or 12 months (or both) by those
receiving the collaborative care intervention, and one
as-treated sample
-
effectivehealthcare.ahrq.gov/products/childhood-depression/protocol
August 24, 2018 - Most notably, the developmental age of the sample (adolescent vs. younger children) is a critical component … age >12 and ≤18): randomized controlled trials (RCTs)
Children (sample age ≤12): RCTs or controlled … All other designs and studies using included designs that do not meet the sample size criterion … When studies with sample sizes of 1,000 or more participants are available for a given intervention and … If large samples are not available, we plan to include studies with smaller sample sizes ****We anticipate
-
effectivehealthcare.ahrq.gov/products/fatty-acids-cardiovascular-disease/research-protocol
April 02, 2015 - Minimum sample sizes (All outcomes: To be determined)
We will aim for a minimum of about 25 RCTs for … lipid outcomes
We expect to include at least 50 RCTs
We will choose RCTs based on a combination of sample … We expect to include at least 50 RCTs
We will choose RCTs based on a combination of sample size, whether … These included descriptions of the study design, sample size intervention(s), follow-up duration, outcomes … Sample size (total)
Age
Sex
Race
Medical history
Risk type
Options: DM
-
effectivehealthcare.ahrq.gov/products/preoperative-testing/research-protocol
May 14, 2013 - unnecessary followup from preoperative tests)
Eligible retrospective studies must clearly include a sample … who ordered and followed up on the tests and in what setting they were ordered; outcome definitions; sample
-
effectivehealthcare.ahrq.gov/products/mrsa-screening-2010/research-protocol
June 02, 2011 - details:
Statistical analyses (statistical test/estimation results)
Test used
Summary measures
Sample … Preventive Services Task Force, 35 as follows:
Was sample definition and selection prospective or retrospective
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mrsa-screening-2010_research-protocol.pdf
January 01, 2010 - Source: www.effectivehealthcare.ahrq.gov
Published Online: October 24, 2011
□ Summary measures
□ Sample … Preventive Services Task Force,35 as follows:
O Was sample definition and selection prospective
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
June 23, 2014 - catalogue one-off studies of interventions (only one study examining a
particular intervention) with low sample … The form will be tested by investigators
using an initial sample of included studies and will be finalized
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-update_research-protocol.pdf
September 20, 2013 - After reviewing a sample of relevant articles, the team will assess the data-collection forms
from the … publication, study location (e.g.,
country, city, state) and time period, population description, sample … will use established concepts
of the quantity of evidence (e.g., numbers of studies, aggregate ending-sample … Complementary and alternative medicine use in a
large pediatric autism sample. … A sample table
is shown below:
Date Section Original Protocol Revised Protocol Rationale
This should
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/quantitative-synthesis-expanded-methods_methods.pdf
March 01, 2013 - Although the use of a
composite outcome as the primary outcome in a clinical trial can reduce sample … In meta-analysis,
sample size is less of a concern than in clinical trials, and thus the motivation … Clinical Trials
Composite outcomes can improve statistical efficiency, increasing power for a given sample … Recommendations
Descriptive study
information
Include information for each study describing the sample … present tables or a graphical representation of the data (forest
plot) including:
The comparison type, sample
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendicitis_executive.pdf
December 01, 2015 - We verified the data extraction
and risk-of-bias assessment in a random sample of 368
noncomparative … Furthermore,
multivariable models were often developed and evaluated
in the same patient sample. … of diagnostic scores, multivariable models
were often developed and evaluated in the same patient
sample … Many had sample sizes that were too
small to reliably detect small or moderate differences
between … • In contrast to the RCTs, NRCSs of alternative testing
strategies attained large sample sizes but
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/preoperative-testing_research-protocol.pdf
May 14, 2013 - preoperative
tests)
• Eligible
retrospective
studies
must
clearly
include
a
sample … who ordered and followed up on the tests and in what setting they were ordered; outcome
definitions; sample
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-surgery-preparation_disposition-comments.pdf
April 30, 2014 - We have provided additional study design
recommendations, particularly with respect to
sample size … We have clarified that we
were referring to the majority of studies when
discussing small sample sizes … We have provided details about the sample size
requirements for such a trial. … We believe that the
required sample size is not prohibitive (even for a
small size consortium) given … , pelvic
abscess, etc.), and that the study will need to be stratified by
anatomical segment, the sample
-
effectivehealthcare.ahrq.gov/products/preterm-birth-terbutaline-pump/research-protocol
August 05, 2010 - Further, the two RCTs included in a published Cochrane review had small sample sizes (52 and 42 participants … Observational studies identified through our scoping literature search consistently have larger sample … setting, duration of followup
Population characteristics: inclusion/exclusion criteria, maternal sample … x
Randomization sequence generation
x
Allocation concealment 4
x
Adequate sample … Assessment of Loss to Followup:
Since the reported sample size could represent either the total number
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
September 08, 2011 - Statistical analyses (statistical test/estimation results)
Test used
Summary measures
Sample … selection of items proposed by Deeks et al.
13
to
inform the USPSTF approach, as follows:
o Was sample … o Did the whole sample or a random selection of the sample, receive
verification using a reference standard
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment-future_research.pdf
January 01, 2014 - However, the
study sample is non-randomized and, therefore, subject to bias. … However, the study sample is non-randomized and, therefore, subject to bias. … Both studies were more than 20 years old, had small sample
sizes, and found no benefit for systemic … Standards for Estimating Proper Sample Sizes
Well-developed statistical methods for estimating the size … …for estimating proper sample sizes.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/single-group-studies_white-paper.pdf
January 01, 2013 - authors planned to
use single group studies, selection criteria for single group studies (minimum sample … However, this interpretation is limited by the small sample size.
F
Figure 2. … Finally, our empirical review was
conducted among the small sample of CERs that had been prepared by … in the randomized two arm trial
designs (though the two arm studies required a 2–4 fold increased sample
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adult-treatment-update_research-protocol.pdf
December 31, 2017 - military settings
Other settings
Study design KQs 1–3: Randomized controlled trials (RCTs) of any sample … size of at least 500,a case-control studies with a sample size
of at least 500a
All other designs … and studies
using included designs that do
not meet the sample size
criterion
Language Studies … For KQ 4, we have
chosen a sample size cutoff of 500 for prospective cohort studies and case-control … We will reassess risk of
bias in a random sample of 10 studies included in the prior review that continue
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_disposition-comments.pdf
June 07, 2013 - non-English articles still have English
abstracts (at least in PubMed), providing some
information like sample … Exploring potential
sample size and effect sizes from abstracts in the
non-English literature (or translating … in our review only 2 studies (both
assessing acute harms) were excluded specifically
based on this sample … Sample sizes for the specific
studies are included in the study characteristic tables. … It would be helpful to mention the sample size
needed for a BRCA1+ population, which would be smaller