-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/colon-cancer-gene-profiling_disposition-comments.pdf
December 14, 2012 - This data, as well as information on our sample turn-around time, which was
listed as unknown, are available … The report shows that the
Oncotype DX assay has been
successfully validated and size
of the sample
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholders-engagement-others_white-paper.pdf
September 01, 2013 - costs
• Greater promotion of the
network across populations
• Reduced fracturing of patient
sample … recruitment of individuals with a specific condition.
10
• Reduced fracturing of the patient sample
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prosthesis_research-protocol.pdf
March 16, 2017 - • Any study design
• No minimum sample size (except not case reports)
• No minimum followup time … adverse effects)
Study Design
• Any study design, including qualitative studies
• No minimum sample … of accessing a LLP
Study Design
• Any study design, including qualitative studies
• No minimum sample … exposures, and
comparators analyzed; outcome definitions; effect modifiers; enrolled and analyzed
sample … These included descriptions of the study design,
sample size, interventions, followup duration, outcomes
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-3-app-G.xlsx
January 01, 2022 - Risk of bias of cannabis cohort studies
Author, Year Did the Study Attempt To Enroll All (or a Random Sample
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-tables-f1-f2-2022-update_0.xlsx
January 01, 2022 - Risk of bias of cannabis cohort studies
Author, Year Did the Study Attempt To Enroll All (or a Random Sample
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-update-surv-rep-1-apps-G1-2.xlsx
January 01, 2022 - Risk of bias of cannabis cohort studies
Author, Year Did the Study Attempt to Enroll All (or a Random Sample
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-screening_research-protocol.pdf
May 18, 2011 - In addition, proponents point out that fecal DNA testing requires only a single whole-
stool sample … Sample Size KQs 1–6: We will not exclude studies based on sample size alone,
although it may be considered … source of study funding, study design characteristics,
recruitment setting/patient-inclusion criteria, sample … expression analyzed, the assay characteristics and
laboratory setting, and the technique used for sample
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-omega-3_research-protocol.pdf
September 02, 2016 - This spreadsheet will capture basic intervention, outcome,
study design, sample size, and whether results … they meet additional operational eligibility criteria used in the original
review (based on minimum sample … intake amounts of n-3 FA), we expect that the primary reason for exclusion
will be based on small sample … and study design) but
would not have been included in the original report (primarily due to small sample … We quantify such
impact as a potential increase in total study population sample size (>20%), a change
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_executive.pdf
April 01, 2012 - Similarly, studies where
the entire sample were subjects with a cerebrovascular
accident, dementias … Inadequate sample size was a factor in many studies. … Adequate sample
size was an issue in these studies. … The second trial evaluated
a dose escalation of fluoxetine in a small sample, and was
suggestive of … A second study, a pilot with small
sample size evaluating dose escalation, showed no effect.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_executive.pdf
December 01, 2011 - (a) Do the differences in performance measures vary
with sample characteristics?
KQ 2. … the
differences in sensitivity and specificity in stool
samples tested within the same lab using the sample … nonstandard intervention for
treatment or prevention of CDI be supported by a
power analysis, adequate sample … Multicenter studies may be necessary to achieve
adequate sample sizes. … How do • Few comparisons are • Comparison of diagnostic • Document stool sample
different methods for
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_disposition-comments.pdf
March 01, 2012 - In my
own experience when a laboratory moves from testing any sample to
only testing loose stools the … “Sample
characteristics” should be “patient and stool sample characteristics.” … The descriptions of the sample, groups, and
parts of the methods are not identical
because there is … We reworded the sample description to clarify
that all subjects had recurrent CDI. … The sample consisted of
subjects who had recurrent CDI.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-g.xlsx
May 29, 2025 - assessments for comparative cohort studies
Study Did the study attempt to enroll all (or a random sample
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/grades-predictive-values_white-paper-2015.pdf
January 01, 2015 - The objective of our methods project was to use a diverse sample of medical
interventions to assess … Results of stratified analyses based on sample size, risk of bias, and magnitude of
effect estimates … First, the size of our sample was limited. … Second, how representative our sample is remains unclear. … Influence of trial sample size on
treatment effect estimates: meta-
epidemiological study.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dementia-nursing-home-characteristics_disposition-comments.pdf
October 23, 2012 - I would like
to briefly comment on the discussion of detection bias (lack of
blinding) and small sample … PwD) manifests itself with such large inter-person or intra person
variability that a really large sample … Sample size is of course also limited by attrition
due to death/decline in this population. … of the interventions/exposures of interest, more studies
need to be conducted with larger sample sizes … Sample size and
design remain important considerations in terms of validity,
but we agree that the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
November 22, 2011 - precision of estimates of analytic validity depends on the specific
statistic used; generally, a sample … interest were used
o Case–control studies
o N>10 subjects (per arm, if there are ≥2 arms); smaller sample … trials
o Nonrandomized comparative studies
o N>10 subjects (per arm, if there are ≥2 arms); smaller sample … because our preliminary searches indicate that non–English-
language studies are few and have small sample … those we have used for other CERs and will include elements
that address population characteristics, sample
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
September 01, 2014 - Core-needle biopsy, which retrieves
a sample of tissue, and open surgical
procedures are the most frequently … stereotactic guidance,
ultrasound guidance, MRI guidance, other guidance,
or freehand), how the biopsy sample … Sixty study arms used vacuum-
assisted methods to obtain the biopsy sample; 80 used
automated methods … MRI-guided biopsies were
evaluated in only six studies with small sample sizes,
leading to substantial … average and high risk
of breast cancer
All biopsy methods Insufficient – Few studies provided within-sample
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/patient-participant-generated-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - the Agency for
Healthcare Research and Quality (AHRQ).7 While the survey represented a very small sample … About half of the
registries in the sample are managed by advocacy organizations, with the others managed … While the sample from the
PGR was subject to limitations and biases, the analysis provided rapid proof … T-Test to look at
differences in progression rate between self-treating participants and a random sample … Other PGRs
may validate the diagnosis for a sample of participants using medical record review or contact
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dental-immunodeficiency-virus-rapid-response.pdf
May 01, 2025 - • All three non-comparative studies were small (sample size: 15 to 63), with follow-up
duration … One study was
conducted in the US,30 and two were in Brazil.31,32 Sample sizes were small. … We rated all three studies as poor quality
(having high risk of bias), due to small sample size, high … Of
these three included studies, two were small, with sample size of less than 25,31,32 and the third … All included studies were single-arm, non-
comparative designs with small sample sizes, limiting causal
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay-future_research.pdf
September 01, 2012 - Studies should have a priori calculation of the
sample size needed for determination of the desired … Sample size not an issue, in
spite of the relatively low prevalence of PCDs,
because the cohorts would … Resource use likely to be moderate; sample
size would depend on number of respondents. … The feasibility of such studies generally does not depend on the desired
sample size. … Studies should have a priori calculation of
the sample size needed for determination of
the desired
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_executive.pdf
August 01, 2012 - Followup times varied from 3 months to
13 years, with sample sizes of 40 to 399 patients. … of limitations in study design, including selection/
spectrum bias as well as (in one study) small sample … without
adjustments for potential confounders and as C in the other
five studies because of their small sample … performance of the SFLC assay varies depending
on the type and distribution of PCDs in the study
sample … Studies should have an
a priori calculation of the sample size needed to determine
the desired precision