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1. Treatment of Depression in Children and Adolescents: A Systematic Review - Evidence Summary (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/Evidence%20Summary_0.pdf
   April 01, 2020 - age >12 and ≤18]: RCTs, children [sample age ≤12]) to 5 capture all available evidence. … We also note special characteristics of the sample required for study inclusions such as females only … CBT) (CDRS): 11.1; 95% CI, 17.68 to 4.52 1 RCT (n=63)64, 65 Imprecision (small sample size), … bupropion (based on BDI) 5.2; 95% CI, 9.31 to 1.09 1 RCT (n=65)68 Imprecision (small sample … CBT) (CDRS): 11.1; 95% CI, 17.68 to 4.52 1 RCT (n=63)64, 65 Imprecision (small sample size),

2. Treatment of Depression in Children and Adolescents: A Systematic Review - Evidence Summary (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/related_files/Evidence%20Summary_0_0.pdf
   April 01, 2020 - age >12 and ≤18]: RCTs, children [sample age ≤12]) to 5 capture all available evidence. … We also note special characteristics of the sample required for study inclusions such as females only … CBT) (CDRS): 11.1; 95% CI, 17.68 to 4.52 1 RCT (n=63)64, 65 Imprecision (small sample size), … bupropion (based on BDI) 5.2; 95% CI, 9.31 to 1.09 1 RCT (n=65)68 Imprecision (small sample … CBT) (CDRS): 11.1; 95% CI, 17.68 to 4.52 1 RCT (n=63)64, 65 Imprecision (small sample size),

3. Asthma-Immunotherapy-2011 Research (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2011_research.pdf
   January 01, 2011 - for her statistical expertise in reliability testing; Susan Duval, Ph.D., for her help estimating sample … Sample size and optimal designs for reliability studies. … (Mark the best responses): A Crude prevalence in total sample Minor flaw B Age adjusted prevalence … Size Sample size justification. … Omitted Poor reporting Prevalence in total sample Crude prevalence in total sample Minor flaw

4. Template for Draft Reports (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_appendixes.pdf
   October 06, 2006 - Sample restricted to cases of balloon angioplasty only. … Not Available Not Applicable Epstein A et al.228 HCUP Nationwide Inpatient Sample LOW (for … size at randomization CABG sample size at randomization Group 1 outcome 1 Specify: … size at randomization CABG sample size at randomization Group 2 outcome 1 Specify: … size at randomization CABG sample size at randomization Group 3 outcome 1 Specify:

5. Ch 9-User-Guide-To-Ocer 130129 (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/ch_9-user-guide-to-ocer_130129.pdf
   September 21, 2012 - Investigators should also consider other factors that may reduce the effective sample size, such as … - The details of the sample size formulas and calculations, including correction for loss to … - Examples include Stata, Confidence Interval Analysis, Power Analysis and Sample Size ( … Sample size (chapter 8). In: Fundamentals of Clinical Trials. 4th edition. … The tyranny of power: Is there a better way to calculate sample size? BMJ. 2009;339:b3985. 6.

6. Research White Paper Biorepositories Addendum Registries For Evaluating Patient Outcomes Third Edition (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/biorepositories-registries-guide-3rd-ed-addendum-white-paper.pdf
   February 01, 2018 - Sample Collection and Storage The planning of the repository includes a determination of the sample … Annotations should include the time and date stamp of sample procurement, processing, and when the sample … Sample Procurement Sample procurement protocols will be based on the sample of interest and the clinical … situation leading to sample acquisition. … It should be noted that many participants will have more than one sample and often more than one sample

7. Research White Paper Biorepositories Addendum Registries For Evaluating Patient Outcomes Third Edition (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/biorepositories-registries-guide-3rd-ed-addendum-white-paper.pdf
   February 01, 2018 - Sample Collection and Storage The planning of the repository includes a determination of the sample … Annotations should include the time and date stamp of sample procurement, processing, and when the sample … Sample Procurement Sample procurement protocols will be based on the sample of interest and the clinical … situation leading to sample acquisition. … It should be noted that many participants will have more than one sample and often more than one sample

8. Meta-Analytic Statistical Inferences for Continuous Measure Outcomes as a Function of Effect Size Metric and Other Assumptions | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/statistical-inference/research
   April 10, 2013 - established by crossing: (1) number of studies in the meta-analysis (k = 10, 20, 50, and 100); (2) mean study sample

9. Disposition of Comments: Comparative Effectiveness Review No. 238 Cervical Ripening in the Outpatient Setting (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-outpatient-setting-comments.pdf
   March 22, 2021 - areas for future research recommendations, such as registry and quality improvement studies, specific sample … Conclusions based on total sample 9,465 women and studies ranked as low or insufficient strength. … Jean Salera- Vieira, AWHONN Discussion Conclusions are based on a total small sample that was unable … We agree that due to the small sample sizes of many of the studies, it is not possible to assess rare … evidence is not strong, and we do recommend future RCTs, in diverse populations, with large enough sample

10. A Prospective Comparison of Evidence Synthesis Search Strategies Developed With and Without Text-Mining Tools | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/research-strategies-text-mining-tools/methods-report
    March 11, 2021 - compared to usual practice (UP) search strategy development in six out of seven reports, but the small sample … TMTs searches appear less sensitive than UP searches in all but one project, but the small sample size … Again, the small sample size precludes significance. … Across all reviews, UP searches seemed to perform better than TMT, but because of the small sample size

11. Methods Research Report: Creating Efficiencies in the Extraction of Data From Randomized Trials (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-creating-efficiencies-extraction-data.pdf
    August 01, 2021 - AHRQ Publication No. 21-EHC006 August 2021 ii Key Messages Purpose of study For a sample … Sample of Randomized Trials We leveraged a random sample of randomized trials originally identified … Sample of Trials Aboud FE, Bougma K, Lemma T, Marquis GS. … Time Savings Data Analysis Results Sample of Randomized Trials A. … Sample of Trials

12. Methods Research Report - Meta-Analytical Statistical Inferences for Continuous Measure Outcomes as a Function of Effect Size Metric and Other Assumptions (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/statistical-inference_research.pdf
    April 01, 2013 - Bias of SMD and UMD as a function of mean sample size ...........................................15 … than for a sample with a large one. … The mean sample size (N) in the literature. … Three vectors of sample sizes were generated as [12, 16, 18, 20, 84], [32, 36, 38, 40, 104], and [62 … Yet, because sample size had little role in results, this concern would seem to be abated.

13. Developing Methods to Assess Health Outcomes in the Presence of Competing Risks for Effectiveness Research | Effective Health Care Program
    effectivehealthcare.ahrq.gov/products/health-outcomes-competing-risks/abstract
    February 11, 2010 - Assessing the applicability of trial evidence to a target sample in the presence of heterogeneity of … propose methods for the quantitative assessment of the applicability of evidence from a trial to a target sample … proposed methods provide quantitative assessment of the applicability of trial evidence to a target sample

14. Simulation-Based Comparison of Methods and Meta-Analysis of Proportions and Rates (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/metanalysis-proportion-rate-comparison_research.pdf
    November 01, 2013 - sizes, N* Vectors of sample sizes for the following choices: All sample sizes small (5-50 patients … per study) All sample sizes medium (51-200 patients per study) All sample sizes large (201-1000 patients … All sample sizes small (50-200 person-years per study) b. … All sample sizes medium (201-500 person-years per study) c. … All sample sizes large (501-10000 person-years per study) d.

15. Appendix-E-Surveillance-Report-1 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendix-e-surveillance-report-1.xlsx
    January 01, 2021 - Observational quality assessment Author, Year Did the study attempt to enroll all (or a random sample … Case control quality assessment Author, Year Did the study attempt to enroll all or random sample of

16. App-E-Opioid-Chronic-Pain-Surveill-Report-1 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveill-report-1.xlsx
    January 01, 2021 - Observational quality assessment Author, Year Did the Study Attempt To Enroll All (or a Random Sample … Case control quality assessment Author, Year Did the Study Attempt To Enroll All or Random Sample of

17. App-E-Opioid-Chronic-Pain-Surveillance-Report-2 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveillance-report-2.xlsx
    January 01, 2021 - Observational studies quality assessment Author, Year Did the Study Attempt To Enroll All (or a Random Sample … Case control studies quality assessment Author, Year Did the Study Attempt To Enroll All or Random Sample

18. Zikmund (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/zikmund.pdf
    December 26, 2012 - of risk concepts Slide  7: A Taxonomy  of Risk Concepts table with 3 columns: “Risk Concept,” “Sample … Incremental Probability Slide  8: A Taxonomy of Risk Concepts (2) table with 3 columns: “Risk Concept,” “Sample … • Relative Probability • Absolute Probability • Comparative Probability • Incremental Probability Sample … Normal/Average Slide  9: A Taxonomy of Risk  Concepts (3) table with 3 columns: “Risk Concept,” “Sample … • Relative Probability • Absolute Probability • Comparative Probability1 • Incremental Probability Sample

19. Testing the Predictive Validity of Strength of Evidence Grades | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/grades-predictive-values/abstract
    September 14, 2015 - Using a large sample of meta-analyses, the outcome of interest is the proportion of stable results over … We expected a sample size of 120 ratings to be sufficient to achieve at least 80% power to compare the … Austrian Cochrane Branch (expected stability) and the proportion of stable summary effects from the sample

20. Machine Learning Methods in Systematic Reviews: Identifying Quality Improvement Intervention Evaluations (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/machine-learning-quality_research.pdf
    September 01, 2012 - The sample citations were screened by one or both of the expert reviewers independently. … An additional set of reviewers also screened a literature sample. Drs. … In this reference sample, LR‘s acceptance rate was 19.3 percent and PS‘s was 11.8 percent. … Reviewers MD and SH screened a different random sample. … The performance in this reference sample was very similar to the original reviewer set.