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  1. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_research-protocol.pdf
    June 11, 2014 - We will not require a minimum sample size for comparative studies addressing Key Questions 1-4. … For estimating sample size, we used the one-tailed z-test and the t-test. … and the possibility of an effect size for continuous outcomes as large as 0.80 or more, the smallest sample … of the numerous possible harm outcomes and study designs, we were not able to determine a specific sample … After reviewing a sample of relevant articles, the team will test and revise the screening and data
  2. effectivehealthcare-admin.ahrq.gov/products/pressure-ulcer-treatment/research-protocol
    December 01, 2019 - Sample size restrictions will not be set a priori, and case series may be used; however, case studies … for pressure ulcer treatments with a date limit of 1985 to the present (i.e., 2011); Table 1 shows a sampleSample search strategy 1 Pressure Ulcer/dh, dt, nu, rt, rh, su, th, ae, co, in, mo, po, to … or imprecise) We will also estimate publication bias by examining whether studies with smaller sample
  3. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/restless-legs-future_research.pdf
    February 01, 2013 - Sample size calculations should ensure adequate power to test selected predefined hypotheses and take … RCTs with sufficient sample sizes can detect meaningful differences in outcomes because randomization … Resource use, size, and duration RCTs are difficult to recruit to, require large sample sizes and … Sample sizes will need to be large, and lost-to-follow-up issues will likely be significant. … Sample size will need to be large given the number of treatment options available.
  4. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/long-term-care-adults_executive.pdf
    November 01, 2012 - NH residents or Medicare home health recipients); no relevant comparison; no relevant settings or sample … We abstracted data based on study design; location (the United States or international); sample populations
  5. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/indirect-comparisons_research-2013.pdf
    January 01, 2013 - Table 1 displays the data from these 54 RCTs, comprising aggregated continuous outcomes (sample mean … That is, where population m is the observed sample m ~ ∆ , , ean of the m ean, is the known … sample variance, and 1, … , , easurem 1, … ents, , , is the num 1, is the unknown true … For simplicity, we assume that every study has sample size 100 and standard deviation of 2 for every … To sample the partially missing data, we compare the results under missing completely at random (MCAR
  6. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-research-report-pilot-promote-entry-data-srdr_0.pdf
    October 01, 2019 - ............................................................................................... 2 Sample … Aim 1: Determine the Sources of Flat File Data That Were Recently Submitted by EPCs to SRDR Sample … We restricted the sample size to nine respondents. … Limitation to Survey The small sample size (nine respondents) is an important limitation to the findings … Methods Aim 1: Determine the Sources of Flat File Data That Were Recently Submitted by EPCs to SRDR Sample
  7. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/depression-brain-injury_research-protocol.pdf
    December 09, 2009 - After reviewing a sample of relevant articles, the team will design the data collection form and test … publication, study location (e.g., country, city, state) and time period, population description, sample … use established concepts of the quantity of evidence (e.g., numbers of studies, aggregate ending sample
  8. effectivehealthcare-admin.ahrq.gov/products/plant-based-chronic-pain-treatment/living-review
    September 01, 2024 - exposures and outcomes RCT and cohort studies with low risk of bias All Designs: Studies with larger sample … Trials were limited by study design and small sample sizes (range 5 to 339; mean 88), particularly for … almost all analyses, there were too few trials to apply graphical or statistical methods to detect small sample … high-THC to CBD ratio products versus placebo to apply such methods, which indicated potential small sample … effects, results are difficult to interpret because a statistical test for small sample effects was
  9. effectivehealthcare-admin.ahrq.gov/products/rotator-cuff-tears-future/research
    December 01, 2019 - The literature limitations included low study quality, disparate treatments and outcomes, small sample
  10. effectivehealthcare-admin.ahrq.gov/products/gaps-pain-management/research-report
    January 01, 2023 - general, longer followup periods, study expansion to multiple sites, and the recruitment of larger sample
  11. effectivehealthcare-admin.ahrq.gov/products/depression-treatment-ssri/research
    December 01, 2019 - Two studies with limited sample sizes and using risperidone as an augmenting agent showed benefit with
  12. effectivehealthcare-admin.ahrq.gov/products/health-careassociated-infections/research
    December 01, 2019 - CINAHL®, and Embase® were searched from January 2006 to January 2012 for English-language studies with sample
  13. effectivehealthcare-admin.ahrq.gov/products/hemorrhage-postpartum/research
    December 01, 2019 - Studies suggested an association between recombinant activated factor VIIa and thromboembolic events, but sample
  14. effectivehealthcare-admin.ahrq.gov/products/ace-inhibitor-arb-future/research
    March 01, 2020 - Few studies involved a representative patient sample treated in a typical clinical setting over a long
  15. effectivehealthcare-admin.ahrq.gov/products/research-gaps-primary-care
    March 01, 2022 - general, longer followup periods, study expansion to multiple sites, and the recruitment of larger sample
  16. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/menopause-protocol-130612.pdf
    June 12, 2013 - different target population (the treatment indication being chronic disease prevention in the study sample … studies Exclude Single arm/case series Exclude Case reports Exclude Minimum duration ≥ 12 weeks Sample … studies Include Single arm/case series Exclude Case reports Exclude Minimum duration ≥12 weeks Sample … Include Single arm/case series Exclude Case reports Exclude Minimum duration 5 yearsa 1 yearb Sample … arm/case series Include Case reports (life-threatening events) Include Minimum duration None Sample
  17. Prognostic Tests (ppt file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/medical-test-reviews-prognostic.ppt
    June 01, 2012 - Did the sample represent patients who would be tested in clinical practice? … Were the results externally validated using an independent sample or internally validated using bootstrap … Were previously established prognostic tests that were used as comparators fitted to the sample data … term=17182986 Fitting a new prognostic test to the sample data (test development sample) by using … Sample Reclassification Table Based on Predicted Outcome Probabilities Step 4: Extracting Statistics
  18. Prognostic Tests (ppt file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/medical-test-reviews-prognostic.ppt
    June 01, 2012 - Did the sample represent patients who would be tested in clinical practice? … Were the results externally validated using an independent sample or internally validated using bootstrap … Were previously established prognostic tests that were used as comparators fitted to the sample data … term=17182986 Fitting a new prognostic test to the sample data (test development sample) by using … Sample Reclassification Table Based on Predicted Outcome Probabilities Step 4: Extracting Statistics
  19. effectivehealthcare-admin.ahrq.gov/products/pediatric-adolescent-cancer-survivorship/protocol
    December 01, 2020 - A random sample of 10 percent of the screened abstracts will be checked by another senior team member … Data extraction will be completed by one study team expert or methodologist and a 10 percent random sample … testing the program theory. 24 This classification will be completed by one team member and a random sample … Assessment will be completed by one team member and a 10 percent sample will be checked by a second reviewer
  20. effectivehealthcare-admin.ahrq.gov/products/prostate-cancer-test/research-protocol
    December 01, 2019 - Followup duration All durations of followup Sample size No studies of PCA3 will be excluded … based on sample size but this element will be considered as part of quality assessment. … No primary matched studies will be excluded based on sample size, but this will be considered part of … Did the whole sample or a random selection of the sample receive verification by using a reference standard … Was the scientific quality (e.g., sample size, study design, blinding, biases, and confounders) of the

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