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221. RENAL MASS AND LOCALIZED RENAL CANCER *the following questions are recommended to address the healthcare tests and/or treatments this program should consider: • What indicators can be used to predict malignancy and/or aggressiveness of… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/renal-mass-and-localized-renal-cancer-the-following-questions-are-recommended-to-address-the-healthcare-tests-andor-treatments-this-program-should-consider-what-indicators-can-be-used-to-predict-malignancy-andor-aggressivene
     November 01, 2017 - Core, Size of Sample, No. of Samples, etc.)

222. Depression-Treatment-Ssri Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_executive.pdf
     April 01, 2012 - Similarly, studies where the entire sample were subjects with a cerebrovascular accident, dementias … Inadequate sample size was a factor in many studies. … Adequate sample size was an issue in these studies. … The second trial evaluated a dose escalation of fluoxetine in a small sample, and was suggestive of … A second study, a pilot with small sample size evaluating dose escalation, showed no effect.

223. Transparency of Reporting Requirements: Omega-3 Fatty Acids and Cardiovascular Disease (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/transparency-omega-3_research-protocol.pdf
     September 02, 2016 - This spreadsheet will capture basic intervention, outcome, study design, sample size, and whether results … they meet additional operational eligibility criteria used in the original review (based on minimum sample … intake amounts of n-3 FA), we expect that the primary reason for exclusion will be based on small sample … and study design) but would not have been included in the original report (primarily due to small sample … We quantify such impact as a potential increase in total study population sample size (>20%), a change

224. Management of Renal Masses and Localized Renal Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/renal-cancer/research
     December 01, 2019 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

225. AHRQ Slide Template 2009 (ppt file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/selecting-evidence.ppt
     January 01, 2010 - Precision Includes sample size, number of studies, and heterogeneity of effect sizes Reporting bias Extent … (II) Precision is the degree of certainty surrounding a result and is determined by sample size, number … Few studies have sufficient sample sizes or duration to adequately assess uncommon or long-term harms … Criteria commonly used to screen OSs for inclusion in CERs: Minimum duration of followup Minimum sample … These criteria may include minimum duration of followup, minimum sample size, a defined threshold for

226. AHRQ Slide Template 2009 (ppt file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/selecting-evidence.ppt
     January 01, 2010 - Precision Includes sample size, number of studies, and heterogeneity of effect sizes Reporting bias Extent … (II) Precision is the degree of certainty surrounding a result and is determined by sample size, number … Few studies have sufficient sample sizes or duration to adequately assess uncommon or long-term harms … Criteria commonly used to screen OSs for inclusion in CERs: Minimum duration of followup Minimum sample … These criteria may include minimum duration of followup, minimum sample size, a defined threshold for

227. Emergency Medical Service/911 Workforce Infection Control and Prevention Issues | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/ems-911-workforce-infection-control/protocol
     December 01, 2022 - Sample questions for the Key Informants include: 1) do they suggest any revision in our analytic framework … We also will capture the sample size of studies, recognizing that some studies may fail to find a significant … difference because of a small sample size.

228. Cancer Quality-ASSIST Supportive Oncology Quality Indicator Set: Feasibility, Reliability, and Validity Testing (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cancer-quality-indicator-testing_research.pdf
     April 01, 2010 - ...........................................................................................1 Study Sample … Study Sample Study inclusion criteria differed somewhat between the sites, based on local populations … At JHH/SKCCC, after abstracting 148 medical records, we concluded that we had an adequate sample to … To assess inter-rater reliability (IRR), all nurses at each site abstracted a sample of records (5%, … nurse abstraction to a physician investigator (SMD) gold standard abstraction for the 9 record IRR sample

229. Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2023 Update -- Surveillance Report 4 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-4.pdf
     January 01, 2023 - The new study was assessed as high risk of bias and had a small sample size (n=60).

230. A Prospective Comparison of Evidence Synthesis Search Strategies Developed With and Without Text-Mining Tools (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-results-search-strategies-developed-with-without-text-mining-tools.pdf
     March 01, 2021 - • TMTs searches appear less sensitive than UP searches in all but one project, but the small sample … Again, the small sample size precludes significance • TMTs neither affected search evaluation time … The target was set to achieve as large a sample as possible within the project timeframe (1 year). … Because of the small sample size, the analysis was limited to descriptive measures, including means, … Finally, the sample size of librarians was small and all had years of experience, so we were not able

231. Research Protocol: Clostridium difficile Infection Update (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
     December 23, 2014 - Do performance measures vary with sample characteristics? c. … The form will be tested by investigators using an initial sample of included studies and will be finalized … bias assessment tool is similar to our approach, we will separately assess risk of bias on only a sample

232. Minimal Modeling Approaches to Value of Information Analysis for Health Research (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-future-value-of-information_research.pdf
     June 01, 2011 - probability that health care technology is cost-effective; QALY = quality-adjusted life-year; SS = sample … to (p)ENBS; pEVPI = population expected value of information; pEVSI = population expected value of sample … We estimated a distribution of mean costs arising out of a sample size similar to that of the Phase … Determining optimal sample sizes for multi-stage randomized clinical trials using value of information … We then took an empty dataset with n observations, n corresponding to the treatment-specific sample

233. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/pressure-ulcer-prevention_research-protocol.pdf
     January 10, 2012 - Sample Size Case studies with only one patient or very small numbers of patients (e.g., <20 patients … If there are large numbers of includable studies for the KQ(s), we may determine a minimum sample-size … Sample Search Strategy (Ovid MEDLINE ® ) Concept Search String 1 Pressure ulcers Pressure Ulcer … or imprecise) We will also estimate publication bias by examining whether studies with smaller sample … Applicability will be estimated by examining the characteristics of the patient populations, the sample

234. Emergency Medical Service/911 Workforce Infection Control and Prevention Issues (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/ems-911-workforce-protocol.pdf
     January 01, 2015 - Sample questions for the Key Informants include: 1) do they suggest any revision in our analytic framework … We also will capture the sample size of studies, recognizing that some studies may fail to find a significant … difference because of a small sample size.

235. EHC Protocol: Making Healthcare Safer IV: Deprescribing to Reduce Medication Harms in Older Adults (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/deprescribing-protocol.pdf
     July 01, 2023 - Depending on the expected volume of literature, the EPC team may opt to have a randomly selected 10% sample … will decide whether it has enough time and resources to ask a second team member to check a 10% sample … If resources permit we will have a second team member check a randomly selected 10% sample of the articles

236. Comparative Effectiveness of Second Generation Antidepressants in the Pharmacologic Treatment of Adult Depression – An Update to a 2007 Report | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/antidepressants-update/research-protocol
     December 01, 2019 - head-to-head comparisons: double-blind, placebo-controlled RCTs Minimum study duration 6 weeks Sample … quality, controlled observational studies Minimum study duration For all studies: 3 months Sample … studies: 3 months Study population Adult inpatients and outpatients with recurrent depression Sample … inpatients and outpatients with major depressive disorder, dysthymia, or subsyndromal depression Sample

237. Acute Migraine Treatment in Emergency Settings | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/migraine-emergency/research-protocol
     December 01, 2019 - care center for treatment of severe headache within the previous 12 months. 8 In a representative sample … We will pre-test this form on a sample of studies. … A sample of studies will be used to pilot both tools. … author, date of publication, study design, setting, treatment groups, inclusion/exclusion criteria, sample … interventions compared with placebo, as well as estimates of which interventions are the best. 26 A burn-in sample

238. The Performance of Fusion Procedures for Degenerative Disease of the Lumbar Spine | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/lumbar-spinal-fusion/protocol
     December 01, 2024 - Sample Search Strategies: Lumbar Fusion … This may be based on sample size sufficiency and number of events. … When quantitative synthesis is not possible, sample size and assessment of variance within individual … If sufficient numbers of RCTs (>10) are available to evaluate small sample effects, quantitative funnel … Sample Search Strategies: Lumbar Fusion Strategies will be adapted for databases

239. Cancer Quality-ASSIST Supportive Oncology Quality Indicator Set: Feasibility, Reliability, and Validity Testing | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/cancer-quality-indicator-testing/research
     January 01, 2020 - Study Sample Study inclusion criteria differed somewhat between the sites, based on local populations … At JHH/SKCCC, after abstracting 148 medical records, we concluded that we had an adequate sample to evaluate … To assess inter-rater reliability (IRR), all nurses at each site abstracted a sample of records (5%, … nurse abstraction to a physician investigator (SMD) gold standard abstraction for the 9 record IRR sample … We also excluded 3 indicators not applicable to the sample or setting (e.g. care during stem cell transplant

240. Interventions for Substance Use Disorders in Adolescents: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/substance-use-disorders-adolescents/protocol
     October 01, 2019 - Population (all KQs) Age: Adolescents (12–20 years inclusive) Exclude if > 20 percent of study sample … using an Evidence Map structure in which we will gather basic data on each article (e.g., study design, sample … of the interventions and comparators; outcome definitions; effect modifiers; enrolled and analyzed sample … Tables will include descriptions of the study design, sample size, intervention(s), followup duration … evidence per GRADE. 29 Based on further evaluation of the evidence base, we may lower the minimum sample