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  1. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/dementia-nursing-home-characteristics_disposition-comments.pdf
    October 23, 2012 - I would like to briefly comment on the discussion of detection bias (lack of blinding) and small sample … PwD) manifests itself with such large inter-person or intra person variability that a really large sampleSample size is of course also limited by attrition due to death/decline in this population. … of the interventions/exposures of interest, more studies need to be conducted with larger sample sizes … Sample size and design remain important considerations in terms of validity, but we agree that the
  2. effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-g.xlsx
    December 18, 2020 - assessments for comparative cohort studies Study Did the study attempt to enroll all (or a random sample
  3. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-4-tables-G1-2.xlsx
    January 01, 2022 - Risk of bias of cannabis cohort studies Author, Year Did the Study Attempt To Enroll All (or a Random Sample
  4. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-1-app-G.xlsx
    January 01, 2023 - Risk of bias of cannabis cohort studies Author, Year Did the Study Attempt To Enroll All (or a Random Sample
  5. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-4-tables-F1-F-2.xlsx
    January 01, 2023 - Risk of bias of cannabis cohort studies Author, Year Did the Study Attempt To Enroll All (or a Random Sample
  6. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/prosthesis_research-protocol.pdf
    March 16, 2017 - • Any study design • No minimum sample size (except not case reports) • No minimum followup time … adverse effects) Study Design • Any study design, including qualitative studies • No minimum sample … of accessing a LLP Study Design • Any study design, including qualitative studies • No minimum sample … exposures, and comparators analyzed; outcome definitions; effect modifiers; enrolled and analyzed sample … These included descriptions of the study design, sample size, interventions, followup duration, outcomes
  7. effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/patient-participant-generated-registries-guide-3rd-ed-addendum-white-paper.pdf
    February 01, 2018 - the Agency for Healthcare Research and Quality (AHRQ).7 While the survey represented a very small sample … About half of the registries in the sample are managed by advocacy organizations, with the others managed … While the sample from the PGR was subject to limitations and biases, the analysis provided rapid proof … T-Test to look at differences in progression rate between self-treating participants and a random sample … Other PGRs may validate the diagnosis for a sample of participants using medical record review or contact
  8. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
    September 01, 2014 - Core-needle biopsy, which retrieves a sample of tissue, and open surgical procedures are the most frequently … stereotactic guidance, ultrasound guidance, MRI guidance, other guidance, or freehand), how the biopsy sample … Sixty study arms used vacuum- assisted methods to obtain the biopsy sample; 80 used automated methods … MRI-guided biopsies were evaluated in only six studies with small sample sizes, leading to substantial … average and high risk of breast cancer All biopsy methods Insufficient – Few studies provided within-sample
  9. effectivehealthcare-admin.ahrq.gov/products/cervical-degenerative-disease/research
    February 01, 2024 - In the total NIS sample, 42 percent of participants had radiculopathy alone and 31 percent had myelopathy … (proportions not reported in the matched sample), 66 percent had a CCI of 0, and 84 percent had 1-2 … The large sample sizes available for administrative data may facilitate evaluation of rare outcomes and … Other limitations of our review include the following: lack of RCT data for many comparisons and small sample … for publication bias using graphical or statistical methods to evaluate any potential impact of small sample
  10. effectivehealthcare-admin.ahrq.gov/products/breast-biopsy-update/clinician
    December 01, 2019 - Core-needle procedures, which remove a small tissue sample through a very small incision, have been widely
  11. effectivehealthcare-admin.ahrq.gov/products/collections/ahrq-nhqdr
    October 01, 2023 - disparities/equity Update the criteria for evaluating benchmarking In each topic brief, pilot a sample
  12. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cannabis-2024-update-appendix-f.xlsx
    January 01, 2024 - Risk of bias of cannabis cohort studies Author, Year Did the Study Attempt To Enroll All (or a Random Sample
  13. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/grades-predictive-values_white-paper-2015.pdf
    January 01, 2015 - The objective of our methods project was to use a diverse sample of medical interventions to assess … Results of stratified analyses based on sample size, risk of bias, and magnitude of effect estimates … First, the size of our sample was limited. … Second, how representative our sample is remains unclear. … Influence of trial sample size on treatment effect estimates: meta- epidemiological study.
  14. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay-future_research.pdf
    September 01, 2012 - Studies should have a priori calculation of the sample size needed for determination of the desired … Sample size not an issue, in spite of the relatively low prevalence of PCDs, because the cohorts would … Resource use likely to be moderate; sample size would depend on number of respondents. … The feasibility of such studies generally does not depend on the desired sample size. … Studies should have a priori calculation of the sample size needed for determination of the desired
  15. effectivehealthcare-admin.ahrq.gov/products/cervical-ripening/research
    March 01, 2022 - Inconsistency (using I 2 ) and small sample size bias (publication bias, if ≥10 studies) were assessed … Limitations of the evidence include the quantity, quality, and sample sizes of trials for specific interventions
  16. effectivehealthcare-admin.ahrq.gov/products/heart-failure-natriuretic-peptide/research-protocol
    December 01, 2019 - Prior to performing the data extraction, a calibration exercise will be conducted using a random sample … The following will also be extracted: blood sample type for BNP measurement (plasma or serum) , assay … Prognosis Papers: Hayden Criteria Study Participation Yes/No/Unsure The study sample … Study Attrition Loss to follow-up (from sample to study population) is not associated with … key characteristics (i.e., the study data adequately represent the sample), sufficient to limit potential
  17. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/disposition-of-comments-cer-192-anxiety-in-children.pdf
    August 31, 2017 - When there is a sufficient sample of studies we examine disorders separately. … that only includes patients with one of these presenting problems against a sample that includes … “other” comparison as there is not a sufficient sample of homogenous “other interventions” to examine … “other” comparison as there is not a sufficient sample of homogenous “other interventions” to examine … “other” comparison as there is not a sufficient sample of homogenous “other interventions” to examine
  18. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_executive.pdf
    August 01, 2012 - Followup times varied from 3 months to 13 years, with sample sizes of 40 to 399 patients. … of limitations in study design, including selection/ spectrum bias as well as (in one study) small sample … without adjustments for potential confounders and as C in the other five studies because of their small sample … performance of the SFLC assay varies depending on the type and distribution of PCDs in the study sample … Studies should have an a priori calculation of the sample size needed to determine the desired precision
  19. effectivehealthcare-admin.ahrq.gov/products/depression-treatment-ssri/research-protocol
    December 01, 2019 - Sample size: There are no restrictions for study sample size. … Prior to performing the data extraction, a calibration exercise will be conducted using a random sample … data will include study characteristics (e.g., first author, country of research origin, study design, sample … size, sample size calculation or power estimate); clinical indications; and study duration or length … episodes of depression, age of first diagnosis, etc.), study outcomes (both of benefit and of harm), sample
  20. effectivehealthcare-admin.ahrq.gov/products/autism-adolescents/research-protocol
    December 01, 2019 - selected this study size based on a previous review of therapies for children with ASD, which used a sample … A cutoff sample size of 20 provides a balance, allowing us to review and comment on adequate literature … In particular, the TEP noted that a sample size of 20 for studies of all types of interventions (e.g. … , medical, behavioral, etc.) takes into account the typically smaller sample sizes in the ASD literature … of publication, study location (e.g., country, city, state) and time period, population description, sample

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