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Showing results for "sample".

121. Empirical and Simulation-Based Comparison of Univariate and Multivariate Meta-Analysis for Binary Outcomes | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/methods-binary-outcomes-evaluation/research
     November 01, 2017 - Most likely, systematic review conclusions from the meta-analyses in the empirical sample would remain … Conclusions In the empirical sample and the simulation study, the numerical difference in the summary

122. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0332_07-29-2010.pdf
     January 01, 2010 - Transcription-mediated amplification of PCA3 and PSA mRNA in urine sample b. … Do measures of AV vary by assay design, method of sample collection, etc.? 3.

123. Developing and Testing a Tool for the Classification of Study Designs in Systematic Reviews of Interventions and Exposures | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/study-design-classification/research
     November 01, 2017 - A sample of 30 studies was used to test the tool. … further revised and tested by another 6 testers using 15 studies randomly selected from the original sample

124. Disposition of Comments Report for Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma-Cell Dyscrasias (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_disposition-comments.pdf
     August 23, 2012 - In addition to total sample size, it would be helpful to add the number of patients with the diagnosis … adoption of these guidelines into clinical practice in the U.S. and abroad, the initial screening blood sample … was accompanied by a urine sample in (at most) 52% of instances.2 In one U.S. center, the estimate … the public reviewer for highlighting the practical difficulties associated with obtaining a urine sample

125. Instrumental Variable Methods in Comparative Safety and Effectiveness Research | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/instrumental-variable-methods/research
     January 01, 2019 - First, standard IV estimators possess a finite sample bias which is inversely proportional to the F … Split-sample Instrumental Variables Estimates of the Return to Schooling. … Appendix Additional Issues Finite Sample Bias. … In small samples, IV estimators based on 2SLS possess substantial finite sample bias. … methods. 26 , 27 Finite sample bias is likely to be more of a problem in the presence of many weak

126. Work Plan for Methods Research on (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/study-design-classification_research.pdf
     December 01, 2010 - A sample of 30 studies was used to test the tool. … Further, the sample of studies that we tested covered a wide range of topics. … Further, at least one study of each design was included in the sample pool. … The sample of studies that we tested covered a wide range of topics. … Sample size requirements for reliability studies. Stat Med 1987;6:441-448. 37.

127. Comparison of Effects as Evidence Evolves From Single Trials to High-Quality Bodies of Evidence | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/grades-predictive-values/white-paper-2015
     November 01, 2017 - Structured Abstract Background The objective of our methods project was to use a diverse sample of

128. Comparative Effectiveness Review No. 272_Genitourinary Syndrome of Menopause: A Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-executive-summary.pdf
     July 01, 2024 - • Harms reporting was limited by sample sizes and short followup duration though most studies did … focused on natural products (i.e., herbal or botanical supplements and vitamins) and were small in sample … trials did not provide adequate statistical reporting) dDowngraded one level for imprecision (total sample … level for imprecision (SD crosses no-effect threshold) fDowngraded two levels for imprecision (total sample

129. Research White Paper - Assessing the Predictive Validity of Strength of Evidence Grades: A Meta-Epidemiological Study (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/grades-predictive-values_white-paper.pdf
     September 01, 2015 - In this sample, the EPC approach to GRADE could not reliably predict the likelihood that individual … our study was to determine the predictive validity of the EPC approach to GRADE based on a diverse sample … For example, in about 20 percent of our sample (presented in Table 1), confidence intervals cross both … Second, how representative our sample is remains unclear. … In addition, our sample was limited to RCTs, so findings are likely not generalizable to research based

130. Calcineurin_Inhibitors_Protocol_FINAL_10-07-2014 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/calcineurin-inhibitor_research-protocol.pdf
     October 08, 2014 - for inclusion, but retrospective studies must use consecutive enrollment or enrollment of a random sample … Duplicate abstraction on a 10-percent random sample will be used to ensure accuracy. … ionization to analyze molecules; effective in detecting therapeutic levels of drugs in a biologic sample … Sample of Search Strategy Table A-1. … Sample Risk of Bias Items ECRI Risk of Bias Item List for Controlled or Comparative studies 1.

131. Therapies for Children with Autism Spectrum Disorders—Research Protocol Document | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/autism/research-protocol
     December 01, 2019 - While controlled trials seem to be increasing, much research is observational, generally with small sample … symptoms Relevant outcomes must be able to be abstracted from data presented in the papers Sample … After reviewing a sample of relevant articles, the Methods and Content Leads will design the data collection … of publication, study location (e.g., country, city, state) and time period, population description, sample … will use established concepts of the quantity of evidence (e.g., numbers of studies, aggregate ending sample

132. Dispostion of Comments Report for Child and Adolescent Exposure to Trauma (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/trauma-child-interventions_disposition-comments.pdf
     February 11, 2013 - compared one type of treatment with another, a wait-list control, or no treatment/placebo using a sample … Overall the report demonstrated the large gaps in knowledge, the small sample sizes, the lack of replication … clinical research in the trauma area) but I would not have much confidence in any study with small sample … Getting larger sample sizes in this area would be difficult because larger samples are quite costly … Sample size should have been given much greater weight in determination of strength of evidence.

133. Self-Measured Blood Pressure: Future Research Needs (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/measuring-blood-pressure-future_research.pdf
     August 01, 2012 - Sample Size for a Randomized Controlled Trial for a Composite CVD Outcome Appendixes ....... 13 … This would require smaller sample sizes than for trials with CVD outcomes as the effect sizes would … An additional approach to decrease the necessary sample size would be to exclude individuals with a … Resource Use, Size, and Duration An RCT, especially one with a long duration and large sample size, … Sample size for a randomized controlled trial for a composite CVD outcome Total sample size for an

134. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pregnancy_hi_impact.pdf
     January 01, 2012 - A new blood test takes a sample of maternal blood during the first trimester in pregnant women interested … “Fetal Nucleic Acid Technology” to detect and isolate circulating fetal DNA from a maternal blood sample … “Fetal Nucleic Acid Technology” to detect and isolate circulating fetal DNA from a maternal blood sample … Sequenom states that circulating fetal DNA can be obtained from a maternal blood sample very early … comfort relative to invasive tests, and the ability of most any physician’s office to perform blood sample

135. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-radiation_executive.pdf
     November 01, 2009 - Primary outcomes were explicitly stated in only three trials, which also reported a priori sample size … All trials enrolled a relatively small sample size, ranging from 15 to 393 patients, and studied different … Most eligible studies were noncomparative in nature and had small sample sizes.

136. Research White Paper: A Framework To Facilitate the Use of Systematic Reviews and Meta-analyses in the Design of Primary Research Studies (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/primary-research-design_research.pdf
     January 01, 2012 - Goudie, et al. assessed a sample of randomized controlled trials (RCTs) published in leading medical … Several publications have proposed methods which can be used to simulate sample size calculations and … Does the proposed study have adequate sample size and power? … Insufficient data: too few primary studies, or studies that are too small (sample size inadequate or … Evidence-based sample size calculations based upon updated meta-analysis.

137. Transparency of Reporting Requirements: Tympanostomy Tubes (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research-protocol.pdf
     September 02, 2016 - This spreadsheet will capture basic intervention, outcome, study design, sample size, and whether results … evidence map to include data on study design, intervention type and duration, population, outcomes, and sample … We quantify such impact as a potential increase in total study population sample size (>20%), a change … Estimating effect size under publication bias: small sample properties and robustness of a random effects … With input from the TEP, study-design and sample-size filters will be implemented, as needed, to contain

138. Evidence Report on the (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/pelvic-pain_research-protocol.pdf
     February 16, 2011 - • Loss to followup: varies by study; to maximize acceptable sample size, we will assume 0 percent … • Statistic: use the two-tailed z-test and the t-test for sample size. … • Sample size: for an RCT with 2 groups, with 100 percent meeting the diagnostic criteria for CPP … • Null hypothesis of effect size of 50 percent: need 64 subjects per study group; a total sample … • Null hypothesis of effect size of 30 percent: need 176 subjects per group; a total sample size

139. Future Research Needs for Treatment of Obstructive Sleep Apnea (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/sleep-apnea-treatment-future_research.pdf
     February 01, 2012 - Sample Discussion Thread: Treatment ................................................................. … Sample Size Calculation for an RCT of Behavioral Interventions To Improve Compliance With CPAP, MAD, … We specifically considered the feasibility of the research questions focusing on potential sample size … size in the thousands, while using surrogate outcomes would need smaller sample sizes. … size in the thousands, while using surrogate outcomes would need smaller sample sizes.

140. Public Deliberation To Elicit Input on Health Topics: Findings From a Literature Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/deliberative-methods/research-2013
     January 01, 2019 - As will be discussed later, recruiting a diverse sample is an important component of public deliberation … Where conveners want a representative sample, random sampling may be used. … Even when the sample is demographically similar to the population of interest, the opinions and views … of participants may not represent those from the population at large because of small sample sizes (