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181. AHRQ Slide Template-Widescreen
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-child-adolesc-mental-health-grand-rounds.pptx
     May 22, 2025 - components. 22 KQ2 Limitations Despite the large body of research, comparative effectiveness and safety … Acute Safety Planning An acute, collaborative intervention offered within the emergency department or … (e.g., review safety plan, means restriction) and may also include an outpatient follow-up appointment … Interventions that targeted trauma (R-FPP, MDT) showed promise Safety planning did not outperform usual … For example, safety planning interventions often included multiple therapeutic strategies (e.g., CBT,

182. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/health-careassociated-infections_research-protocol.pdf
     August 26, 2011 - , the Agency for Healthcare Research and Quality (AHRQ) has funded the Comprehensive Unit-based Safety … Improving patient safety through infection control: a new healthcare imperative. … Michigan Health and Hospital Association Keystone Center for Patient Safety and Quality. … Assessing the Evidence for Context-Sensitive Effectiveness and Safety of Patient Safety Practices: Developing … RECOMMENDED ELEMENTS FOR REPORTING ON PATIENT SAFETY PRACTICES (Source: Shekelle et al. 2010)

183. Psoriasis-Chronic Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_executive.pdf
     November 01, 2012 - main research gaps identified in this meta-analysis was the lack of comparative effectiveness and safety … To date, no comparative effectiveness review comparing the effectiveness and safety of biologic systemic … In patients with chronic plaque psoriasis, what is the comparative safety of systemic biologic agents … Study Evaluating the Efficacy and Safety of Etanercept and Acitretin in Korean Patient With Moderate … Safety and efficacy study on etanercept in patients with plaque psoriasis.

184. AHRQ’s Evidence-based Practice Center Program- Synthesizing evidence to improve health care practice and delivery (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/epc-evidence-reviews-federal-agencies.pdf
     July 01, 2020 - Department of Health and Human Services that is charged with improving the quality, safety, efficiency … effectivehealthcare. ahrq.gov/topics/field-triage-glascow/ research-2017) National Highway Traffic Safety

185. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0496_12-30-2011.pdf
     January 01, 2011 - Nominator: Individual Nomination Summary: The nominator questions the comparative renal safety … What is the comparative renal safety of different contrast media used in radiographic imaging?

186. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - However, experts generally indicated a need for more trials to determine the safety and efficacy of … However, experts commented that acceptance could be limited by cost and safety concerns. … However, they expressed concerns regarding long- term safety and efficacy. … However, they commented that acceptance could be limited by safety concerns. … data and postmarket safety evaluation—set forth by FDA.

187. Disposition of Comments for Progestogens for Prevention of Preterm Birth (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth-disposition-121205.pdf
     September 07, 2012 - We will update the report to include new information concerning the safety of 17-OHP. … With regard to safety we have updated the report as discussed above. … However, this was the basis for the safety signal discovered by the FDA. … Therefore, there appear to be differences in efficacy and safety. … The omission of the safety signal is a major concern.

188. worker-health-protocol-150526 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/worker-health_research-protocol.pdf
     May 26, 2015 - have promoted integrated approaches to improving worker health: National Institute for Occupational Safety … TWH is defined as a “strategy integrating occupational safety and health protection with health promotion … injury.11,12 Other TWH interventions have integrated work site-based health promotion into on-site safety … Health and safety outcomes (e.g., cardiovascular events or incidence of work- related injuries) Source … o KQ 2a: Health and safety outcomes: Mortality; incidence of injuries, cardiovascular disease or cancer

189. FRN 35 - Preventive Pharmacological Treatments for Migraine in Adults: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-future_research.pdf
     April 01, 2013 - KQ 3: Which patient characteristics predict the effectiveness and safety of pharmacologic treatments … Safety OnabotulinumtoxinA resulted in adverse effects and treatment discontinuation due to adverse … Future research is needed to address efficacy, comparative effectiveness, and safety in terms of the … long-term safety and effectiveness chronic migraine NCT00216606 The Effectiveness and Safety of Topiramate … of Topiramate for the Prevention of Migraine Safety NCT00301665 Efficacy and Safety Study of Dysport

190. Vte-Prophyalaxis Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_executive.pdf
     May 01, 2013 - hospitalization by roughly $10,000 and $20,000, respectively.3 Thus, VTE is an important patient safety … What are the comparative effectiveness and safety of IVC filters to prevent PE in hospitalized patients … What are the comparative effectiveness and safety of pharmacologic prophylaxis for prevention of VTE … What are the comparative effectiveness and safety of pharmacologic prophylaxis for prevention of VTE … RCTs should evaluate the comparative effectiveness and safety of LMWHs in obese patients.

191. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0122_06-29-2009.pdf
     January 01, 2009 - Description Nominator: Individual Nomination Summary: The nominator is interested in the safety …  This topic will move forward as a new systematic review that will address the safety, effectiveness

192. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (Amended) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/masks-prevention-covid-healthcare-community-amended-protocol.pdf
     July 02, 2020 - tested in laboratory settings,4 but there is a lack of evidence on the clinical effectiveness and safety … types of facemasks in healthcare workers and in the community and to address the effectiveness and safety … Clinical Evidence Assessment: Safety of Extended Use and Reuse of N95 Respirators. 2020. https://assets.ecri.org

193. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-insulin_executive.pdf
     September 01, 2008 - However, the addition of insulin to treatment Comparative Effectiveness, Safety, and Indications of … , do premixed insulin analogues differ from other commonly used insulin preparations with regard to safety … Does the effectiveness or safety of the new premixed insulin analogue regimens vary across the following … What are the effectiveness and safety of the new premixed insulin analogue regimens in individuals on … Comparative Effectiveness, Safety, and Indications of Insulin Analogues in Premixed Formulations for

194. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/registries-guide_executive.pdf
     April 01, 2007 - used to evaluate outcomes for diverse purposes ranging from the natural history of a disease, to the safety … evaluation of safety and effectiveness … • To reduce losses to followup, safety studies can be enhanced by collecting enough information … • For safety studies, personnel are appropriately trained to ask about complaints or adverse events … • For safety studies, the risks and/or benefits of products, devices, or processes under study are

195. Topic 0556 CE of Treatments for Diabetic Peripheral Neuropathy NSD SJ clean (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0658-140831.pdf
     July 19, 2014 - What is the comparative safety and effectiveness of treatment options to delay or from Nominator: reverse … What is the comparative safety and effectiveness of treatment options to improve the symptoms of diabetic

196. Hi Les, (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rtc-design-principles_research.pdf
     January 01, 2009 - more efficient RCT designs may be possible.1,2 In other situations, comparative evidence about the safety … , a new test may affect patient outcomes through other attributes of the procedure itself, such as safety … As shown in Figure 1, differences in test safety and test accuracy always deserve consideration. … Alternatively, if the new test is intended to provide other attributes such as improved safety, the … Other pathways The next step is to assess differences in test safety and other attributes of the test

197. Future Research Needs for First- and Second-Generation Antipsychotics for Children and Young Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-future_research.pdf
     February 01, 2012 - The stakeholders prioritized general medication safety and effectiveness issues across disorders over … The needs identified ranged from methodological considerations to needs emphasizing medication safety … It is possible that some of these effectiveness and safety questions could be evaluated with complex … some safety outcomes tend to be more homogenous across studies (e.g., weight gain). … The extant literature lacks the use of standardized pediatric side-effect scales (e.g., the Safety

198. ? For women in the postpartum period, what is the effectiveness and safety of screening and treatment for depression? Please use the USPSTF framework, which considers not only screening but followup treatment and management. The treatment… | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/for-women-in-the-postpartum-period-what-is-the-effectiveness-and-safety-of-screening-and-treatment-for-depression-please-use-the-uspstf-framework-which-considers-not-only-screening-but-followup-treatment-and-management-the-t

199. Antipsychotics-Children Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children_research-protocol.pdf
     June 04, 2010 - longitudinal data on which to base conclusive clinical practice recommendations, especially with regard to safety … • Wording has been changed to clarify that the CER will compare efficacy, effectiveness and safety … in elderly with dementia- related psychosis Perphenazine Approved 1965 Schizophrenia Adults Safety … Limited evidence in children <12 years Use and safety have not been evaluated in other childhood … Adults Pediatric use: safety & effectiveness not established in patients <18 yr 1. agranulocytosis

200. Arthritis-Psoriatric Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
     April 01, 2012 - More importantly, it is unclear how the effectiveness and safety of different types of combination … Head-to-head randomized controlled trials are needed to establish the comparative efficacy and safety … Efficacy and safety of anti-TNF therapies in psoriatic arthritis: an observational study from the British … Safety and efficacy of adalimumab in treatment of patients with psoriatic arthritis who had failed … Etanercept treatment of psoriatic arthritis: safety, efficacy, and effect on disease progression.