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effectivehealthcare.ahrq.gov/sites/default/files/s1.pdf
October 01, 2007 - landmark legislation creates new
opportunities and a renewed national interest in improving the quality, safety … As the lead Federal agency for improving the quality,
safety, and effectiveness of health care, AHRQ’ … identifying sources of data for research,
and developing methodologies for studying health outcomes,
safety … This supplement is meant to serve as a resource to
scientists investigating the safety and effectiveness … development rapidly
brings new therapies to clinical care, there is an expanding
need for research on the safety
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/crohns-disease_executive.pdf
February 01, 2014 - Safety
Study Characteristics of RCTs
Of 64 RCTs, 45 (70 percent) reported a safety outcome
of interest … safety outcomes
at study visits. … exact safety outcomes of interest. … We summarized the safety results in
Table E. … For KQ3, on safety, the SOE for nearly every comparison
was graded as insufficient or low for safety-related
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effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1512.pdf
December 29, 2015 - The drug’s long-term safety may also affect its
adoption. … Of note, long-
term safety and efficacy data were released after we solicited expert comments on this … The experts also thought that long-term safety and efficacy data for
baricitinib are needed. … Novartis Pharmaceuticals. 16 week efficacy
and 5 year long term efficacy, safety and
tolerability … Safety and efficacy of baricitinib at 24 weeks
in patients with rheumatoid arthritis who
have had
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0623-140828.pdf
April 25, 2014 - Individual
Nomination The topic was nominated by an individual who is specifically interested in the safety … ART)
Outcome(s): Conception, pregnancy, and safety and efficacy
Key Questions What are the best options … for fertility treatment, in terms of safety and effectiveness?
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effectivehealthcare.ahrq.gov/sites/default/files/toc.pdf
January 01, 2007 - The Comparative Effectiveness and Safety Emerging Methods
Symposium: A Tribue to Harry A. … Emerging Methods in Comparative Effectiveness and Safety:
Symposium Overview and Summary.Med Care. … Methodologic Challenges to Studying Patient Safety and Comparative
Effectiveness. … Brown, and Richard Platt, for the Vaccine Safety
Datalink Rapid Cycle Analysis Team. … Real-Time Vaccine Safety Surveillance for the
Early Detection of Adverse Events.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/living-systematic-reviews-full-text-articles-white-paper.pdf
January 01, 2024 - Safety and
efficacy of low-dose Medical Cannabis oils
in Multiple Sclerosis. … Long-
term effectiveness and safety of medical
cannabis administered through the metered-
dose Syqe … Safety and efficacy of medical
cannabis in fibromyalgia. … Safety and
efficacy of low-dose medical cannabis oils
in multiple sclerosis. … Safety and efficacy of medical
cannabis in fibromyalgia.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/off-label-use-research-priorities_research.pdf
May 01, 2009 - patients, and policymakers seeking unbiased information
about the outcomes, clinical effectiveness, safety … We used FDA safety
warnings as a proxy for serious side-effects and drug interactions. … , volume and the combined cost and
market index, and safety and the combined index respectively. … Similarly, support is lacking for their use in
dementia where safety concerns have been raised about … /Cost
Exclude Not
Found Usesd
Volume +
Safety No
Cost
Inadequate
Volume Only
Aggregate
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_executive.pdf
January 01, 2006 - In addition,
efficacy and safety may vary for individual
drugs within a class. … Comparative Effectiveness and Safety of
Analgesics for Osteoarthritis
Executive Summary
Effective Health … and no
evidence on CV safety … • Almost no data are available on CV safety. … Comparative Effectiveness and Safety of
Analgesics for Osteoarthritis.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_surveillance.pdf
October 29, 2012 - , 4, 5 and 6 up to date
• Expert opinion: conclusions still valid
• There are no new significant safety … using searches through August, 2011 and
addressed six key questions to evaluate effectiveness and safety … Administration (FDA), Health Canada, and Medicines and Healthcare Products Regulatory
Agency (MHRA) safety … Taken
into consideration the totality of evidence (i.e., updating signals, expert opinion, and safety … Experts: Still valid
Safety surveillance alerts: No
Conclusion: Up to date
7
Table 1.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-nom-length-stay-supplement.pdf
June 27, 2019 - volume capacity for those hospitals that have
greater patient demand than bed supply including many safety … Hospitals and health systems, including CEOs, will use this information to improve patient
safety and
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-ambulatory-therapeutics_research.pdf
July 01, 2009 - patients, and policymakers seeking unbiased information
about the outcomes, clinical effectiveness, safety … The initial results from DARTNet data analyses indicate that the comparative
effectiveness and safety … The findings of our safety analyses suggest
that sulfonylureas may put patients at increased risk of … and the safety and efficacy of commonly
used ambulatory therapies. … Total
numbers of safety events are high enough in the replication cohort to suggest that safety
studies
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-256-telehealth-women-preventive-services-executive-summary.pdf
June 01, 2022 - depression, fear of partner, coercive control, self-
efficacy, post-traumatic stress disorder, and safety … Low
IPV,
continued
Safety
behaviors
Telephone calls;
computerized encounters;
in-person interviews … referral
4 RCTs (1,175)
Telehealth is at least as effective as
usual care for increasing safety … Noninteractive online tool 1 RCT (231) No difference in patient reported anxiety
using a tailored, online safety
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND__0399_01-07-2011.pdf
January 01, 2011 - Outcome(s): Survival, quality of life, palliation, and safety/adverse events.
2. … tumor recurrence post-transplantation, prevention of tumor
progression while on transplant list, and safety … Outcome(s): Survival, quality of life, palliation, and safety/adverse events.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
January 01, 2015 - If needed, warnings are issued when
safety signals become apparent through case reports and post-approval … Additionally, the evidence regarding the comparative effects and
safety of other monotherapies among … • The inclusion of the safety outcomes of impaired renal function, urinary tract infections,
genital … The abstract review phase will be designed to identify studies reporting the effectiveness or
safety … Comparative
Effectiveness and Safety of Oral Diabetes Medications for Adults With Type 2 Diabetes.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/health-systems-research.pdf
October 01, 2017 - All of the health-systems we spoke with have either centralized and
standardized quality, safety, and … Script for Quality, Safety and Process Leaders Interviews
viii
Background
In its report … All of the health-systems we spoke
with have either centralized and standardized quality, safety, and … KIs felt that
knowing the balance of efficacy and safety of active treatments, rather than just the … Script for Quality, Safety and Process Leaders Interviews
Process for Reviewing and Using Evidence
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-hospitalizations_research.pdf
October 01, 2008 - patients, and policymakers seeking unbiased information
about the outcomes, clinical effectiveness, safety … serious infections and congestive heart failure
leading to hospitalizations in studies of medication safety … Medicaid (TennCare) databases have been used extensively for post marketing
studies of medication safety … and we are evaluating the safety of tumor necrosis factor alpha
(TNF-α) antagonists in a cohort of … accuracy of computerized definitions for selected clinical
conditions will facilitate studies on the safety
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/prevent-hai-protocol.pdf
April 16, 2024 - emerged as an important value in
healthcare.1,2 Balancing these often-competing interests of patient safety … health system costs associated
with infection prevention and/or sustainability, and healthcare worker safety … Cost, safety, and environmental impact of reprocessing
single-use medical devices: A systematic review … Dublin (Ireland): Health
Research Board; 2023 Sep. https://www.hrb.ie/publications/publication/cost-safety-and … /returnPage/1/
https://www.hrb.ie/publications/publication/cost-safety-and-environmental-impact-of-reprocessing-single-use-medical-devices-a-systematic-revi
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
October 01, 2011 - We included studies that
evaluate the safety, efficacy, or effectiveness of the
included medications … We
also included studies that report safety in patients with
rheumatoid arthritis or who were taking … We included studies that evaluate the safety, efficacy, or
effectiveness of the previously mentioned … Evidence was insufficient
to make reliable judgments about GI safety of
nabumetone. … Comparative
effectiveness and safety of analgesics for osteoarthritis.
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
January 01, 2015 - The
abstract review phase was designed to identify studies
reporting the effectiveness or safety of … Key Questions 3a and 3b: Comparative
Safety
Of 145 studies identified for Key Question 3, 137 were … Therefore, most safety comparisons represent
shorter term results unless specifically stated in the … Summary of the moderate- to high-strength evidence on the comparative safety of
diabetes medications … Cardiovascular safety
of sulfonylureas: a meta-analysis of randomized clinical trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholder-engagement_research.pdf
September 01, 2011 - AHRQ) Effective Healthcare (EHC)
Program has noted the challenge of decisionmaking when evidence of safety … content areas, including: report enhancements designed to support
decision making when evidence of safety … dispute, comparative effectiveness reviews (CERs), which
synthesize the available evidence of the safety … on contextual factors that might
influence coverage decisions when there is uncertainty about the safety … “Treating Type 2
Diabetes, The Oral Diabetes Drugs,
comparing Effectiveness, Safety, and Price.”