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  1. S1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s1.pdf
    October 01, 2007 - landmark legislation creates new opportunities and a renewed national interest in improving the quality, safety … As the lead Federal agency for improving the quality, safety, and effectiveness of health care, AHRQ’ … identifying sources of data for research, and developing methodologies for studying health outcomes, safety … This supplement is meant to serve as a resource to scientists investigating the safety and effectiveness … development rapidly brings new therapies to clinical care, there is an expanding need for research on the safety
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/crohns-disease_executive.pdf
    February 01, 2014 - Safety Study Characteristics of RCTs Of 64 RCTs, 45 (70 percent) reported a safety outcome of interest … safety outcomes at study visits. … exact safety outcomes of interest. … We summarized the safety results in Table E. … For KQ3, on safety, the SOE for nearly every comparison was graded as insufficient or low for safety-related
  3. effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1512.pdf
    December 29, 2015 - The drug’s long-term safety may also affect its adoption. … Of note, long- term safety and efficacy data were released after we solicited expert comments on this … The experts also thought that long-term safety and efficacy data for baricitinib are needed. … Novartis Pharmaceuticals. 16 week efficacy and 5 year long term efficacy, safety and tolerability … Safety and efficacy of baricitinib at 24 weeks in patients with rheumatoid arthritis who have had
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0623-140828.pdf
    April 25, 2014 - Individual Nomination The topic was nominated by an individual who is specifically interested in the safety … ART) Outcome(s): Conception, pregnancy, and safety and efficacy Key Questions What are the best options … for fertility treatment, in terms of safety and effectiveness?
  5. effectivehealthcare.ahrq.gov/sites/default/files/toc.pdf
    January 01, 2007 - The Comparative Effectiveness and Safety Emerging Methods Symposium: A Tribue to Harry A. … Emerging Methods in Comparative Effectiveness and Safety: Symposium Overview and Summary.Med Care. … Methodologic Challenges to Studying Patient Safety and Comparative Effectiveness. … Brown, and Richard Platt, for the Vaccine Safety Datalink Rapid Cycle Analysis Team. … Real-Time Vaccine Safety Surveillance for the Early Detection of Adverse Events.
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/living-systematic-reviews-full-text-articles-white-paper.pdf
    January 01, 2024 - Safety and efficacy of low-dose Medical Cannabis oils in Multiple Sclerosis. … Long- term effectiveness and safety of medical cannabis administered through the metered- dose Syqe … Safety and efficacy of medical cannabis in fibromyalgia. … Safety and efficacy of low-dose medical cannabis oils in multiple sclerosis. … Safety and efficacy of medical cannabis in fibromyalgia.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/off-label-use-research-priorities_research.pdf
    May 01, 2009 - patients, and policymakers seeking unbiased information about the outcomes, clinical effectiveness, safety … We used FDA safety warnings as a proxy for serious side-effects and drug interactions. … , volume and the combined cost and market index, and safety and the combined index respectively. … Similarly, support is lacking for their use in dementia where safety concerns have been raised about … /Cost Exclude Not Found Usesd Volume + Safety No Cost Inadequate Volume Only Aggregate
  8. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_executive.pdf
    January 01, 2006 - In addition, efficacy and safety may vary for individual drugs within a class. … Comparative Effectiveness and Safety of Analgesics for Osteoarthritis Executive Summary Effective Health … and no evidence on CV safety … • Almost no data are available on CV safety. … Comparative Effectiveness and Safety of Analgesics for Osteoarthritis.
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_surveillance.pdf
    October 29, 2012 - , 4, 5 and 6 up to date • Expert opinion: conclusions still valid • There are no new significant safety … using searches through August, 2011 and addressed six key questions to evaluate effectiveness and safety … Administration (FDA), Health Canada, and Medicines and Healthcare Products Regulatory Agency (MHRA) safety … Taken into consideration the totality of evidence (i.e., updating signals, expert opinion, and safety … Experts: Still valid Safety surveillance alerts: No Conclusion: Up to date 7 Table 1.
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-nom-length-stay-supplement.pdf
    June 27, 2019 - volume capacity for those hospitals that have greater patient demand than bed supply including many safety … Hospitals and health systems, including CEOs, will use this information to improve patient safety and
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-ambulatory-therapeutics_research.pdf
    July 01, 2009 - patients, and policymakers seeking unbiased information about the outcomes, clinical effectiveness, safety … The initial results from DARTNet data analyses indicate that the comparative effectiveness and safety … The findings of our safety analyses suggest that sulfonylureas may put patients at increased risk of … and the safety and efficacy of commonly used ambulatory therapies. … Total numbers of safety events are high enough in the replication cohort to suggest that safety studies
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-256-telehealth-women-preventive-services-executive-summary.pdf
    June 01, 2022 - depression, fear of partner, coercive control, self- efficacy, post-traumatic stress disorder, and safety … Low IPV, continued Safety behaviors Telephone calls; computerized encounters; in-person interviews … referral 4 RCTs (1,175) Telehealth is at least as effective as usual care for increasing safety … Noninteractive online tool 1 RCT (231) No difference in patient reported anxiety using a tailored, online safety
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND__0399_01-07-2011.pdf
    January 01, 2011 - Outcome(s): Survival, quality of life, palliation, and safety/adverse events. 2. … tumor recurrence post-transplantation, prevention of tumor progression while on transplant list, and safety … Outcome(s): Survival, quality of life, palliation, and safety/adverse events.
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
    January 01, 2015 - If needed, warnings are issued when safety signals become apparent through case reports and post-approval … Additionally, the evidence regarding the comparative effects and safety of other monotherapies among … • The inclusion of the safety outcomes of impaired renal function, urinary tract infections, genital … The abstract review phase will be designed to identify studies reporting the effectiveness or safety … Comparative Effectiveness and Safety of Oral Diabetes Medications for Adults With Type 2 Diabetes.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/health-systems-research.pdf
    October 01, 2017 - All of the health-systems we spoke with have either centralized and standardized quality, safety, and … Script for Quality, Safety and Process Leaders Interviews viii Background In its report … All of the health-systems we spoke with have either centralized and standardized quality, safety, and … KIs felt that knowing the balance of efficacy and safety of active treatments, rather than just the … Script for Quality, Safety and Process Leaders Interviews Process for Reviewing and Using Evidence
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-hospitalizations_research.pdf
    October 01, 2008 - patients, and policymakers seeking unbiased information about the outcomes, clinical effectiveness, safety … serious infections and congestive heart failure leading to hospitalizations in studies of medication safety … Medicaid (TennCare) databases have been used extensively for post marketing studies of medication safety … and we are evaluating the safety of tumor necrosis factor alpha (TNF-α) antagonists in a cohort of … accuracy of computerized definitions for selected clinical conditions will facilitate studies on the safety
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/prevent-hai-protocol.pdf
    April 16, 2024 - emerged as an important value in healthcare.1,2 Balancing these often-competing interests of patient safety … health system costs associated with infection prevention and/or sustainability, and healthcare worker safety … Cost, safety, and environmental impact of reprocessing single-use medical devices: A systematic review … Dublin (Ireland): Health Research Board; 2023 Sep. https://www.hrb.ie/publications/publication/cost-safety-and … /returnPage/1/ https://www.hrb.ie/publications/publication/cost-safety-and-environmental-impact-of-reprocessing-single-use-medical-devices-a-systematic-revi
  18. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
    October 01, 2011 - We included studies that evaluate the safety, efficacy, or effectiveness of the included medications … We also included studies that report safety in patients with rheumatoid arthritis or who were taking … We included studies that evaluate the safety, efficacy, or effectiveness of the previously mentioned … Evidence was insufficient to make reliable judgments about GI safety of nabumetone. … Comparative effectiveness and safety of analgesics for osteoarthritis.
  19. effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
    January 01, 2015 - The abstract review phase was designed to identify studies reporting the effectiveness or safety of … Key Questions 3a and 3b: Comparative Safety Of 145 studies identified for Key Question 3, 137 were … Therefore, most safety comparisons represent shorter term results unless specifically stated in the … Summary of the moderate- to high-strength evidence on the comparative safety of diabetes medications … Cardiovascular safety of sulfonylureas: a meta-analysis of randomized clinical trials.
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholder-engagement_research.pdf
    September 01, 2011 - AHRQ) Effective Healthcare (EHC) Program has noted the challenge of decisionmaking when evidence of safety … content areas, including: report enhancements designed to support decision making when evidence of safety … dispute, comparative effectiveness reviews (CERs), which synthesize the available evidence of the safety … on contextual factors that might influence coverage decisions when there is uncertainty about the safety … “Treating Type 2 Diabetes, The Oral Diabetes Drugs, comparing Effectiveness, Safety, and Price.”

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