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Showing results for "safer iii critical".

61. Technical Brief: Whole Body Vibration Therapy for Osteoporosis | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/osteoporosis-vibration-therapy/research-protocol
    December 01, 2019 - Alternative therapies, including weight-bearing exercise, may also increase bone density 16,17 and are safer … has a potential conflict of interest but is still deemed to have a viewpoint or specific expertise critical … What criteria (clinical effectiveness, safety, FDA approval, market value, others) are the most critical … Prevalence and trends in low femur bone density among older US adults: NHANES 2005–2006 compared with NHANES III

62. AHRQ Evidence-Based Practice Center (EPC) Program Research Gaps Summary: Pain Management (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
    January 01, 2023 - %3Awhite_paper&f%5B4%5D=field_product_type%3Amethods_guide_chapter&sort_by=field_product_pub_date iii … ................................................................................................... iii … The EPC Program supports the overall AHRQ mission of producing evidence to make healthcare safer, higher … Interventions • Studies to comprehensively address acute pain, which is a critical focus for these

63. Obesity (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - FDA approved the drug on July 17, 2012, on the basis of two completed, phase III trials. … Liraglutide is under investigation in a four-part phase III clinical trial (SCALE). … FDA approved the drug on June 27, 2012, on the basis of three completed phase III trials. … Less-invasive, safer endoluminal approaches for weight loss are being investigated to potentially extend … FDA approved the drug on July 17, 2012, basing its decision on two completed phase III trials.

64. Telehealth During COVID-19 | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/virtual-health-covid/protocol
    January 01, 2023 - Contextual and Key Questions III. Analytic Framework IV. Methods V. References VI. … been discussed with the Stakeholders during the topic refinement phase; neither change was considered critical … III. … The Joanna Briggs Institute Critical Appraisal tools for use in JBI Systematic Reviews Checklist for … You Might Also Like Research Protocol Aug 02, 2024 Making Healthcare Safer

65. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
    June 16, 2010 - important that quality of life evidence be at least qualitatively reviewed and that the principles of critical … We believe this approach will add perspective to some of these critical questions. … 2010 10 I wonder if having some information related to patient age and sex would be useful, i.e., safer … Double-blind, placebo-controlled, randomized phase III trial of darbepoetin alfa in lung cancer patients … The Key Questions III. Analytic Framework IV. Methods A.

66. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/health-careassociated-infections_research-protocol.pdf
    August 26, 2011 - Epidemiologists of America; SSI = surgical site infection; VAP = ventilator-associated pneumonia III … Making Health Care Safer: Reducing Bloodstream Infections. … Closing the Quality Gap: A Critical Analysis of Quality Improvement Strategies. … experiments Source: www.effectivehealthcare.ahrq.gov Published Online: August 26, 2011 21 III … Closing the Quality Gap: A Critical Analysis of Quality Improvement Strategies.

67. Safety of Vaccines Used for Routine Immunization in the United States | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/safety-vaccines/protocol
    January 01, 2021 - III. … We will use the McHarm scale, a tool for structured critical appraisal of adverse event data reported … clinical trial" or "clinical trial, phase i" or "clinical trial, phase ii" or clinical trial, phase iii … clinical trials, phase i as topic/ or clinical trials, phase ii as topic/ or clinical trials, phase iii … You Might Also Like Research Protocol Nov 25, 2024 Making Healthcare Safer

68. Disposition of Comments Report for Enzyme-Replacement Therapies for Lysosomal Storage Disease (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/lysosomal-storage-diseases-therapies_disposition-comments.pdf
    January 01, 2014 - Orphanet rare Dis 2011), and as it has become safer, it is being piloted for treatment of other MPS … However, this does indicate the critical need for newborn screening of LSD’s. 1. … , where the underlying disease severity and extent of disease progression before ERT is begun are critical … , where the underlying disease severity and extent of disease progression before ERT is begun are critical … Please include open label extension of Muenzer phase II/III study.

69. Comparative Effectiveness of Epoetin and Darbepoetin for Managing Anemia in Patients Undergoing Cancer Treatment–An Update to the 2006 Report | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/cancer-anemia-update/research-protocol
    December 01, 2019 - important that quality of life evidence be at least qualitatively reviewed and that the principles of critical … We believe this approach will add perspective to some of these critical questions. … I wonder if having some information related to patient age and sex would be useful, i.e., safer in pediatric … Double-blind, placebo-controlled, randomized phase III trial of darbepoetin alfa in lung cancer patients … You Might Also Like Systematic Review Aug 20, 2024 Treatment of Stage I-III

70. Disposition of Comments Report for Allergen-Specific Immunotherapy for the Treatment of Allergic Rhinoconjunctivitis and/or Asthma (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/asthma-immunotherapy-2010_disposition-comments.pdf
    January 01, 2010 - mechanistic)] may show effects which cannot, and are not reproduced in larger field trials (Phase IIB/Phase III … However, this subsequent Phase IIB/III clinical study, of 400+ ragweed-allergic patients with RCS, … effect based on dose would be a useful determinant to ascertain therapeutic effect, as this is a critical … strongly that it should be stated in the executive summary that although SLIT appears to be much safer

71. Assessing Harms when Comparing Medical Interventions | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/methods-guidance-harms/methods
    May 01, 2020 - If a specific adverse event is not reported, it is generally safer for CER authors to assume that they … Reader's guide to critical appraisal of cohort studies: 1. Role and design. … non-randomised intervention studies Health Technology Assessment (Winchester, England) 2003;7(27):iii-x … A critical guide to case series reports. Spine 2003;28:1631-1634. 63. … Treatment: A Systematic Review Rapid Evidence Product Sep 14, 2023 Making Healthcare Safer

72. Radiation Therapy for Brain Metastases: A Systematic Review | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/radiation-brain-metastases/protocol
    June 01, 2021 - Critical questions include the following: What adverse cognitive effects are to be expected after radiation … III. … Given that the reliability and validity of the data are critical to answer key question 4 and adverse … The critical appraisal result will be used for sensitivity analyses where appropriate (e.g., excluding … in Adults: A Systematic Review Research Protocol Aug 02, 2024 Making Healthcare Safer

73. Disposition of Comments Report for The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
    September 29, 2014 - When referring to harms, especially in relation solely to clinical harms, it is critical to take into … Comments regarding this critical limitation are provided for in the Applicability section above. … except to say “Higher doses tend to have greater risk” and (cautiously) that methadone may actually be safer … but its effects on other organs, such as the lungs and heart, can continue for eight to 59 hours. iii … iii Food and Drug Administration (FDA), “Public Health Advisory: Methadone Use for Pain Control May

74. Impact of Healthcare Worker Safety and Wellness: A Systematic Review | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/worker-safety-wellness/protocol
    December 01, 2024 - Key Questions III. Logic Model IV. Methods V. References VI. Definition of Terms VII. … III. … At the center of the model are critical interventions needed to reduce burnout among HCWs. … To Err is Human: Building a Safer Health System. … Medical Services and 911 Workforces Research Protocol Dec 11, 2024 Making Healthcare Safer

75. 8 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
    November 01, 2008 - Nonetheless, when a significant proportion of published trials fail to report an important or critical … interventions were well tolerated.‖ If a specific adverse event is not reported, it is generally safer … Reader’s guide to critical appraisal of cohort studies: 1. Role and design. … non-randomised intervention studies Health Technology Assessment (Winchester, England) 2003;7(27):iii–x … A critical guide to case series reports.

76. 8 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
    November 01, 2008 - Nonetheless, when a significant proportion of published trials fail to report an important or critical … interventions were well tolerated.‖ If a specific adverse event is not reported, it is generally safer … Reader’s guide to critical appraisal of cohort studies: 1. Role and design. … non-randomised intervention studies Health Technology Assessment (Winchester, England) 2003;7(27):iii–x … A critical guide to case series reports.

77. Disposition of Comments Report for CER 203 ADHD (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-203-adhd-disposition-comments.pdf
    January 01, 2018 - Some issues seem less than critical at this time. … Burcu M, Zito JM, Ibe A, Safer DJ. … Our work is driven by our commitment to promote mental health as a critical part of overall wellness … These outcomes were seen as being both patient-centered and most critical for decisionmaking across … Pelham, W.E., Fabiano, G.A., Waxmonsky, J.G., Greiner, A.R., Gnagy, E.M., Pelham III, W.E., Coxe, S.

78. Comparative Effectiveness of Screening for Methicillin-Resistant Staphylococcus aureus (MRSA) | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/mrsa-screening-2010/research-protocol
    December 01, 2019 - Health Technol Assess 2003;7(27):iii-x, 1-173. Carey TS, Boden SD. … A critical guide to case series reports. Spine 2003;28:1631-34. … Systems for grading the quality of evidence and the strength of recommendations I: critical appraisal … You Might Also Like Research Protocol Nov 25, 2024 Making Healthcare Safer … Developmental Screening and Followup White Paper May 31, 2024 Making Healthcare Safer

79. Management of Renal Masses and Localized Renal Cancer | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/renal-cancer/research-protocol
    December 01, 2019 - Were the critical co-interventions balanced across intervention groups? 4.2. … Pierorazio, P.M., et al., Laparoscopic radical nephrectomy for large renal masses: critical assessment … Preventive Medical Strategies Systematic Review Aug 20, 2024 Treatment of Stage I-III … Developmental Screening and Followup Research Protocol Aug 02, 2024 Making Healthcare Safer

80. Stroke Prevention in Atrial Fibrillation Patients: A Systematic Review Update | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/stroke-afib-update/research-protocol
    September 01, 2019 - Unfortunately, two critical issues regarding stroke prevention in AF remain: (1) despite existing evidence … studies showed that DOACs are at least as efficacious and, except for high dose dabigatran, significantly safer … III. … align with the evaluation of bleeding outcomes in the systematic review from 2013. 6/28/2017 III … Preventive Medical Strategies Research Protocol Aug 02, 2024 Making Healthcare Safer