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  1. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary2/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd-august-2014
    August 26, 2014 - 0.12 mmol/L (CI, 0.18 to 0.05 mmol/L) (2.08 mg/dL [CI, 3.29 to 0.88 mg/dL]), diabetes incidence by a relative … in a composite measure of all CVD events at 6.6 years of follow-up (relative risk, 0.71 [95% CI, 0.51 … , as well as trends in the distribution of CVD and CVD risk factors over time. … Effect on haemostatic variables and other coronary risk factors. … , and metabolic risk factors.
  2. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd
    November 24, 2020 - Interventions were associated with a lower risk of cardiovascular events (pooled relative risk, 0.80 … Studies rated as poor were excluded. 14 Poor-quality studies typically had several major risks of bias … Behavioral counseling was associated with lower risk of the composite outcomes of any CVD events (risk … Population risks of 7.5% and 10% translate to numbers needed to treat of 67 (95% CI, 49 to 103) and 50 … men at high cardiovascular risk.
  3. www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication-november-2016
    November 13, 2016 - CI, 0.63 to 0.78]). 6 Among the study populations, the proportion of CVD events prevented (ie, the relative … , similar relative risk estimates were observed among those classified at a higher vs lower CVD event … risk. 10 , 23 Given similar relative risk reductions, the absolute magnitude of benefit that an intervention … It is possible that the relative risk reduction in this group is higher than in adults with a lower LDL-C … Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from
  4. www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/perinatal-depression-interventions-to-prevent
    April 22, 2025 - initiated interventions during the second or third trimester of pregnancy. 2 Ongoing assessment of risks … interventions were associated with a 17% reduction in the likelihood of perinatal depression (pooled relativerisk [RR], 0.83 [95% CI, 0.72 to 0.95]; 21 studies; n=4,974; I 2 =0.0). … , unselected populations (31% vs. 5% risk reduction, respectively). … Depression during pregnancy: a risk factor for adverse neonatal outcomes?
  5. www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/statin-use-in-adults-preventive-medication
    August 23, 2022 - risk estimation tools. … (18 trials; n = 85,816; relative risk [RR], 0.92 [95% CI, 0.87 to 0.98]; absolute risk difference [ARD … statin therapy and myopathy or rhabdomyolysis, although these events were uncommon, so the estimates of relative … discussion for persons at borderline risk, and recommend consideration of risk enhancers to refine risk … Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from
  6. www.uspreventiveservicestaskforce.org/home/getfilebytoken/3w8Wr9wwAyAqUJWmJo_bL-
    February 01, 2014 - Background: Mutations in breast cancer susceptibility genes (BRCA1 and BRCA2) are associated with increased risks … Force (USPSTF) rec- ommended in 2005 that women whose family histories are associated with increased risks … Deleterious mutations in the BRCA1 and BRCA2 genes are associated with increased risks for breast, ovarian … For example, women with BRCA1 mutations have higher risks for ovar- ian cancer than those with BRCA2 … Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case
  7. www.uspreventiveservicestaskforce.org/uspstf/document/treatment-evidence-summary/gestational-diabetes-mellitus-screening-january-2014
    May 28, 2013 - We used the Mantel–Haenszel method for relative risks and the inverse variance method for pooling mean … For dichotomous outcomes, we computed relative risk to estimate between-group differences. … risk. … Third, this review assessed the risks and benefits of treating GDM but not those of screening for this … determine the glucose thresholds and treatment targets at which GDM treatment benefits outweigh the risks
  8. www.uspreventiveservicestaskforce.org/uspstf/document/addendum-to-screening-for-ovarian-cancer-evidence-update-for-the-us-preventive-services-task-force-reaffirmation-recommendation-statement/ovarian-cancer-screening-2012
    April 15, 2012 - ovarian cancer mortality was observed in the intervention group compared with those receiving usual care (relative … A patented ovarian cancer risk algorithm was used to assign an ovarian cancer risk score to women in … The risk score classified women as normal, intermediate, or high risk; women with normal results were … conditional multiple logistic regression was mentioned in this unmatched study, which did not present relativerisks).
  9. www.uspreventiveservicestaskforce.org/uspstf/recommendation/diabetes-mellitus-type-2-in-adults-screening-2003
    February 04, 2003 - Two well‐performed RCTs have shown that tight glycemic control reduces the relative risk for development … Further, there were no reductions in stroke (Relative Risk [RR], 1.11), heart failure (RR, 0.91), angina … events by about the same relative percentage among those with diabetes as among those without diabetes (relative … over a 5‐year period. 48 Aspirin reduces CHD in both diabetics and nondiabetics, with a comparable relative … experience any adverse effect of labeling. 52 Early detection could subject individuals to the potential risks
  10. www.uspreventiveservicestaskforce.org/uspstf/document/risk-factors-and-other-epidemiologic-considerations-for-cervical-cancer-screening-a-narrative-review-for-the-us-preventive-services-task-force/cervical-cancer-screening-2012
    October 15, 2011 - Share to WhatsApp Share to Email Print archived Risk … Newer data suggest that CIN1 does not predict any meaningful risk for CIN3 14 , 15 . … Potential harms of treating CIN include immediate, short-term, and long-term risks. … Given the potential short- and long-term risks associated with treatment and the high likelihood of HPV … Whether this balance of risks and benefits is similar for women in their early 20s is unclear.
  11. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/aspirin-to-prevent-cardiovascular-disease-preventive-medication
    April 26, 2022 - 79,334) or nonfatal ischemic stroke (n = 54,947); aspirin was associated with statistically significant relative … Panel III (ATP III) guidelines were published and statin use became more widespread, showed larger relativerisk reductions than RCTs conducted after 2001; confidence intervals of these relative risk estimates … tools for bleeding risks associated with low-dose aspirin use for the primary prevention of CVD. … Effect of proton pump inhibitors on risks of upper and lower gastrointestinal bleeding among users of
  12. www.uspreventiveservicestaskforce.org/home/getfilebytoken/b-rsH7WPpNC3uL9NeoXBfF
    May 08, 2018 - Pooled relative risks of incontinence with radical prostatectomy were 2.27 (95% CI, 1.82-2.84; I2 = 0.0% … difference; RCT, randomized clinical trial; RR, relative risk. a Conservative management encompasses … difference; RCT, randomized clinical trial; RR, relative risk. a Conservative management encompasses … difference; RCT, randomized clinical trial; RR, relative risk. a Conservative management encompasses … difference; RCT, randomized clinical trial; RR, relative risk. a Conservative management encompasses
  13. www.uspreventiveservicestaskforce.org/home/getfilebytoken/QtuWfedsMmUb_sAuKWdsGg
    December 31, 2014 - cancer mortality was observed in the intervention group compared with those receiving usual care (relative … A patented ovarian cancer risk algorithm was used to assign an ovarian cancer risk score to women in … The risk score classified women as normal, intermediate, or high risk; women with normal results were … conditional multiple logistic regression was mentioned in this unmatched study, which did not present relativerisks).
  14. www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication
    August 23, 2022 - Estimate CVD risk using a CVD risk estimator. … (18 trials; n = 85,816; relative risk [RR], 0.92 [95% CI, 0.87 to 0.98]; absolute risk difference [ARD … statin therapy and myopathy or rhabdomyolysis, although these events were uncommon, so the estimates of relative … discussion for persons at borderline risk, and recommend consideration of risk enhancers to refine risk … Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from
  15. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/osteoporosis-screening
    January 14, 2025 - Screening was associated with reduced hip (pooled relative risk [RR], 0.83 [95% CI, 0.73-0.93]; 3 RCTs … for hip fracture (10-year estimated FRAX risks at baseline ranged from 6.7% to 11.6%). … Merlijn et al, 30 2019 General practice registries in the Netherlands; only women with ≥1 clinical risks … without BMD input into calculation; some studies used electronic health record data to determine FRAX risks … ; RR, relative risk; SCORE, Simple Calculated Osteoporosis Risk Estimation; SOFSURF, Study of Osteoporotic
  16. www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
    September 28, 2021 - Predictive models that combine risk factors to identify pregnant persons at risk for preeclampsia, such … It is strengthened by new evidence from additional trials supporting reduced risks of perinatal mortality … The USPSTF found evidence of a reduction in risk for preterm birth (pooled relative risk [RR], 0.80 [ … Persons at risk of preeclampsia are defined based on the presence of 1 or more high-risk factors (history … Risk Level a Risk Factors Recommendation High b History of preeclampsia
  17. www.uspreventiveservicestaskforce.org/home/getfilebytoken/Njxn2r3qtWKdBf2_VhS2Aw
    April 01, 2016 - Data Synthesis: In CVD primary prevention trials, cancer mor- tality (relative risk [RR], 0.96 [95% CI … BMD = British Male Doctors; CRC = colorectal cancer; PHS = Physicians' Health Study; RR = relative risk … therapy with at least 5 years of 75 to 325 mg of aspirin per day at ages 50 to 65 years outweighed the risksRelative risk estimates for aspirin use and CRC incidence and mortality differ from ours in part because … Bleeding risks with aspirin use for primary prevention in adults: a systematic evidence review for the
  18. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/statin-use-in-adults-preventive-medication
    August 23, 2022 - Although relative risk estimates were similar across groups, absolute benefits varied according to baseline … Benefits of statins were not restricted to patients with severely elevated lipid levels, because similar relative … Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from … Risks associated with statin therapy: a systematic overview of randomized clinical trials. … ALT, alanine aminotransferase; CV, cardiovascular; MA,meta-analysis; MI,myocardial infarction; RR, relative
  19. www.uspreventiveservicestaskforce.org/home/getfilebytoken/uhtgkZVs_bpNJ4_G4fXUay
    March 01, 2014 - Future improvements in risk assessment tools will help cli- nicians better individualize patients’ risks … Overdiagnosis of lung cancer and the risks of radiation are real harms, although their magnitude is uncertain … The relative risk for all-cause mortality in the DLCST was 1.46 (CI, 0.99 to 2.15). … When these 3 fair- or good-quality trials were com- bined in a meta-analysis, the relative risk for lung … exposure, family history, and history of other lung diseases are important when assessing patients’ risks
  20. www.uspreventiveservicestaskforce.org/uspstf/recommendation/human-immunodeficiency-virus-hiv-infection-screening
    June 11, 2019 - of AIDS-related events (4.5% vs 7.0%; relative risk [RR], 0.65 [95% CI, 0.44-0.95]). … initiation of ART within 6 months of CD4 cell counts decreasing to less than 500/mL 3 , there were greater risks … CI, 0.02-0.22]), 34 and 3 observational studies (Partners of People on ART—A New Evaluation of the Risks … treatment of HIV infection are small, and the clinical benefits of ART substantially outweigh the potential risks … Benefits and risks of antiretroviral therapy for perinatal HIV prevention.

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