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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary2/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd-august-2014
August 26, 2014 - 0.12 mmol/L (CI, 0.18 to 0.05 mmol/L) (2.08 mg/dL [CI, 3.29 to 0.88 mg/dL]), diabetes incidence by a relative … in a composite measure of all CVD events at 6.6 years of follow-up (relative risk, 0.71 [95% CI, 0.51 … , as well as trends in the distribution of CVD and CVD risk factors over time. … Effect on haemostatic variables and other coronary risk factors. … , and metabolic risk factors.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd
November 24, 2020 - Interventions were associated with a lower risk of cardiovascular events (pooled relative risk, 0.80 … Studies rated as poor were excluded. 14 Poor-quality studies typically had several major risks of bias … Behavioral counseling was associated with lower risk of the composite outcomes of any CVD events (risk … Population risks of 7.5% and 10% translate to numbers needed to treat of 67 (95% CI, 49 to 103) and 50 … men at high cardiovascular risk.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication-november-2016
November 13, 2016 - CI, 0.63 to 0.78]). 6
Among the study populations, the proportion of CVD events prevented (ie, the relative … , similar relative risk estimates were observed among those classified at a higher vs lower CVD event … risk. 10 , 23
Given similar relative risk reductions, the absolute magnitude of benefit that an intervention … It is possible that the relative risk reduction in this group is higher than in adults with a lower LDL-C … Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from
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www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/perinatal-depression-interventions-to-prevent
April 22, 2025 - initiated interventions during the second or third trimester of pregnancy. 2 Ongoing assessment of risks … interventions were associated with a 17% reduction in the likelihood of perinatal depression (pooled relative … risk [RR], 0.83 [95% CI, 0.72 to 0.95]; 21 studies; n=4,974; I 2 =0.0). … , unselected populations (31% vs. 5% risk reduction, respectively). … Depression during pregnancy: a risk factor for adverse neonatal outcomes?
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/statin-use-in-adults-preventive-medication
August 23, 2022 - risk estimation tools. … (18 trials; n = 85,816; relative risk [RR], 0.92 [95% CI, 0.87 to 0.98]; absolute risk difference [ARD … statin therapy and myopathy or rhabdomyolysis, although these events were uncommon, so the estimates of relative … discussion for persons at borderline risk, and recommend consideration of risk enhancers to refine risk … Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/3w8Wr9wwAyAqUJWmJo_bL-
February 01, 2014 - Background: Mutations in breast cancer susceptibility genes
(BRCA1 and BRCA2) are associated with increased risks … Force (USPSTF) rec-
ommended in 2005 that women whose family histories
are associated with increased risks … Deleterious mutations in the BRCA1 and BRCA2
genes are associated with increased risks for breast, ovarian … For example,
women with BRCA1 mutations have higher risks for ovar-
ian cancer than those with BRCA2 … Average risks of breast and ovarian cancer associated with BRCA1 or
BRCA2 mutations detected in case
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www.uspreventiveservicestaskforce.org/uspstf/document/treatment-evidence-summary/gestational-diabetes-mellitus-screening-january-2014
May 28, 2013 - We used the Mantel–Haenszel method for relative risks and the inverse variance method for pooling mean … For dichotomous outcomes, we computed relative risk to estimate between-group differences. … risk. … Third, this review assessed the risks and benefits of treating GDM but not those of screening for this … determine the glucose thresholds and treatment targets at which GDM treatment benefits outweigh the risks
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www.uspreventiveservicestaskforce.org/uspstf/document/addendum-to-screening-for-ovarian-cancer-evidence-update-for-the-us-preventive-services-task-force-reaffirmation-recommendation-statement/ovarian-cancer-screening-2012
April 15, 2012 - ovarian cancer mortality was observed in the intervention group compared with those receiving usual care (relative … A patented ovarian cancer risk algorithm was used to assign an ovarian cancer risk score to women in … The risk score classified women as normal, intermediate, or high risk; women with normal results were … conditional multiple logistic regression was mentioned in this unmatched study, which did not present relative … risks).
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/diabetes-mellitus-type-2-in-adults-screening-2003
February 04, 2003 - Two well‐performed RCTs have shown that tight glycemic control reduces the relative risk for development … Further, there were no reductions in stroke (Relative Risk [RR], 1.11), heart failure (RR, 0.91), angina … events by about the same relative percentage among those with diabetes as among those without diabetes (relative … over a 5‐year period. 48 Aspirin reduces CHD in both diabetics and nondiabetics, with a comparable relative … experience any adverse effect of labeling. 52 Early detection could subject individuals to the potential risks
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www.uspreventiveservicestaskforce.org/uspstf/document/risk-factors-and-other-epidemiologic-considerations-for-cervical-cancer-screening-a-narrative-review-for-the-us-preventive-services-task-force/cervical-cancer-screening-2012
October 15, 2011 - Share to WhatsApp
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Risk … Newer data suggest that CIN1 does not predict any meaningful risk for CIN3 14 , 15 . … Potential harms of treating CIN include immediate, short-term, and long-term risks. … Given the potential short- and long-term risks associated with treatment and the high likelihood of HPV … Whether this balance of risks and benefits is similar for women in their early 20s is unclear.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/aspirin-to-prevent-cardiovascular-disease-preventive-medication
April 26, 2022 - 79,334) or nonfatal ischemic stroke (n = 54,947); aspirin was associated with statistically significant relative … Panel III (ATP III) guidelines were published and statin use became more widespread, showed larger relative … risk reductions than RCTs conducted after 2001; confidence intervals of these relative risk estimates … tools for bleeding risks associated with low-dose aspirin use for the primary prevention of CVD. … Effect of proton pump inhibitors on risks of upper and lower gastrointestinal bleeding among users of
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/b-rsH7WPpNC3uL9NeoXBfF
May 08, 2018 - Pooled relative risks of incontinence with radical
prostatectomy were 2.27 (95% CI, 1.82-2.84; I2 = 0.0% … difference; RCT, randomized clinical trial;
RR, relative risk.
a Conservative management encompasses … difference; RCT, randomized clinical trial;
RR, relative risk.
a Conservative management encompasses … difference; RCT, randomized clinical trial; RR,
relative risk.
a Conservative management encompasses … difference; RCT, randomized clinical trial; RR,
relative risk.
a Conservative management encompasses
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/QtuWfedsMmUb_sAuKWdsGg
December 31, 2014 - cancer
mortality was observed in the intervention group compared with those receiving usual care
(relative … A patented ovarian cancer risk algorithm was used to assign an ovarian cancer risk score to
women in … The risk score classified women as
normal, intermediate, or high risk; women with normal results were … conditional multiple logistic regression was mentioned
in this unmatched study, which did not present relative … risks).
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication
August 23, 2022 - Estimate CVD risk using a CVD risk estimator. … (18 trials; n = 85,816; relative risk [RR], 0.92 [95% CI, 0.87 to 0.98]; absolute risk difference [ARD … statin therapy and myopathy or rhabdomyolysis, although these events were uncommon, so the estimates of relative … discussion for persons at borderline risk, and recommend consideration of risk enhancers to refine risk … Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/osteoporosis-screening
January 14, 2025 - Screening was associated with reduced hip (pooled relative risk [RR], 0.83 [95% CI, 0.73-0.93]; 3 RCTs … for hip fracture (10-year estimated FRAX risks at baseline ranged from 6.7% to 11.6%). … Merlijn et al, 30 2019
General practice registries in the Netherlands; only women with ≥1 clinical risks … without BMD input into calculation; some studies used electronic health record data to determine FRAX risks … ; RR, relative risk; SCORE, Simple Calculated Osteoporosis Risk Estimation; SOFSURF, Study of Osteoporotic
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
September 28, 2021 - Predictive models that combine risk factors to identify pregnant persons at risk for preeclampsia, such … It is strengthened by new evidence from additional trials supporting reduced risks of perinatal mortality … The USPSTF found evidence of a reduction in risk for preterm birth (pooled relative risk [RR], 0.80 [ … Persons at risk of preeclampsia are defined based on the presence of 1 or more high-risk factors (history … Risk Level a
Risk Factors
Recommendation
High b
History of preeclampsia
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Njxn2r3qtWKdBf2_VhS2Aw
April 01, 2016 - Data Synthesis: In CVD primary prevention trials, cancer mor-
tality (relative risk [RR], 0.96 [95% CI … BMD = British Male Doctors; CRC = colorectal cancer; PHS = Physicians' Health Study; RR = relative risk … therapy with
at least 5 years of 75 to 325 mg of aspirin per day at
ages 50 to 65 years outweighed the risks … Relative risk estimates for aspirin use and CRC
incidence and mortality differ from ours in part because … Bleeding risks with aspirin use for primary prevention in adults: a
systematic evidence review for the
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/statin-use-in-adults-preventive-medication
August 23, 2022 - Although relative risk estimates were similar across groups, absolute benefits varied according to baseline … Benefits of statins were not restricted to patients with severely elevated lipid levels, because similar relative … Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from … Risks associated with statin therapy: a systematic overview of randomized clinical trials. … ALT, alanine aminotransferase; CV, cardiovascular; MA,meta-analysis; MI,myocardial infarction; RR, relative
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/uhtgkZVs_bpNJ4_G4fXUay
March 01, 2014 - Future improvements in risk assessment tools will help cli-
nicians better individualize patients’ risks … Overdiagnosis of lung cancer
and the risks of radiation are real harms, although their
magnitude is uncertain … The relative risk for all-cause mortality in the DLCST was
1.46 (CI, 0.99 to 2.15). … When these 3 fair- or good-quality trials were com-
bined in a meta-analysis, the relative risk for lung … exposure, family
history, and history of other lung diseases are important
when assessing patients’ risks
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/human-immunodeficiency-virus-hiv-infection-screening
June 11, 2019 - of AIDS-related events (4.5% vs 7.0%; relative risk [RR], 0.65 [95% CI, 0.44-0.95]). … initiation of ART within 6 months of CD4 cell counts decreasing to less than 500/mL 3 , there were greater risks … CI, 0.02-0.22]), 34 and 3 observational studies (Partners of People on ART—A New Evaluation of the Risks … treatment of HIV infection are small, and the clinical benefits of ART substantially outweigh the potential risks … Benefits and risks of antiretroviral therapy for perinatal HIV prevention.