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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - ................................ 2
Threats From the Right: Loss to Followup, Censoring, Competing Risks … Finally, competing risks must be considered. … Competing
risks can lead to missing data in certain settings; sometimes a study may be interested in … See Lau et al. for a more involved discussion of competing risks and
missing data, as well as analytic … “Competing Risk Regression
Models for Epidemiologic Data.”
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_disposition-comments.pdf
August 01, 2012 - on benefits and risks of
screening, monitoring and treatment. … has been made to
describe the impact of CKD stage (e.g., 1
versus 2 versus 3) on the benefits and
risks … Stages 1 to 3 CKD
conferred significant increases in the relative risk of all 5
parameters assessed … factors (e.g. diabetes,
hypertension, etc.) on the benefits and
risks of CKD screening, monitoring … factors including race on the
benefits and risks of CKD screening,
monitoring and treatment.
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effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_2012-12-11.pdf
January 01, 2012 - The surgery carries significant risks of morbidity and mortality, and the drug
therapy has undesired … No Risk
Evaluation and Mitigation Strategy was required. … However, some patients who are super-morbidly obese are
ineligible for surgery because of surgical risks … Qsymia approval, informing
prescribers and “female patients of reproductive potential” of potential risks … , and such patients can have a high tolerance for
risk.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0174_10-20-2009.pdf
January 01, 2009 - What are the associated risks, adverse effects, and potential harms of physical and
rehabilitative therapies
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0251_05-20-2010.pdf
January 01, 2010 - Staff-Generated PICOS:
Population(s): Patients at risk of developing pressure ulcers and patients with … pressure
ulcers
Intervention(s): Identification of patients at risk for, prevention, and treatment … specialized mattresses,
undergarments, creams, and nursing routines
Outcome(s): For measures of risk … How can we identify patients at risk for pressure ulcers in the hospital or long-term
care setting … what is the evidence for the validity and reliability of various
instruments for estimating these risks
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioids-oa-protocol.pdf
June 29, 2019 - many special considerations when using (or misusing)
opioids.5
Aside from misuse, other important risks … The risks of harm may also
be exacerbated by the high frequency at which older adults see multiple providers … anti-inflammatory drugs) due to
impaired liver or kidney function, hypertension,22-24 other cardiac risks … Medicine text Pain
Management and the Opioid Epidemic: Balancing Societal and Individual Benefits and Risks … Pain management and the opioid epidemic : balancing societal
and individual benefits and risks of prescription
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0488_12-27-2011.pdf
January 01, 2011 - Staff-Generated PICO
Population(s): People (primarily adults) at high risk for pancreatic cancer ( … sensitivity and specificity), practical issues (ease of use,
costs, operator training), and potential risks … characteristics (e.g., family history, chronic
pancreatitis, diabetes) compared with patients with no risk
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_disposition-comments.pdf
June 07, 2013 - increased risk?? decreased risk?? … question from this reviewer is whether an
OR was actually calculated for cohort studies or whether
a relative … age-specific incidences (rates) to
probabilities, then, assuming that the odds ratios
were estimates of relative … risks, applied the OR to the
probabilities. … However, it is
interesting to note that the results of relative risk by
duration of oral contraceptive
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/benefits-harms-modeling_research.pdf
November 19, 2009 - been directly studied.11 Instead, there is good
evidence on the prevalence of diabetes in specific risk … the implications of screening for impaired glucose
tolerance among 45-year-olds with above-average risk … Tradeoffs
All testing procedures and treatment decisions are associated with benefits, risks,
and … Simultaneously weighing
the likelihood of encephalitis and the risks and benefits of brain biopsy and … For example, in very low risk populations (very low disease prevalence), even
very specific tests can
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0002_03-04-2008.pdf
January 01, 2008 - What are the health risks and benefits of aggressive versus less aggressive control
of diabetes mellitus
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0095_04-10-2009.pdf
January 01, 2009 - Outcome(s): Diagnostic accuracy and improvements in mortality, and risks associated
with undiagnosed
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effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_june_2012.pdf
January 01, 2012 - The surgery carries significant risks of morbidity and mortality, and the drug
therapy has undesired … However, some super-morbidly obese patients are ineligible for surgery because of surgical
risks and … obese patients who might otherwise benefit from bariatric surgery are ineligible
because of surgical risks … loss is widely recognized as correlating with improved
outcomes and reduction of diabetes-related risks … , and such patients can have a high tolerance for risk.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/dot-plots-methods.pdf
October 01, 2021 - risk with 95 percent confidence intervals as
well as the absolute rates in each arm. … risks) in the same format as the dot plots. … risk and 95 percent
confidence interval. … and control groups along with the proportion of patients who experienced an
outcome in each group, relative … risk;
SOE = strength of evidence
Figure 2.
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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/biorepositories-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - personalized medicine requires understanding each person’s individual make-
up and how that affects their risk … These data can enable longitudinal research
studies to examine the biological and genetic risk factors … • Risks and Benefits. … The consent process should
involve a description of the physical risks associated with collecting the … Variants in
the ATP-binding cassette transporter
(ABCA7), apolipoprotein E ϵ4,and the risk
of late-onset
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_disposition-comments.pdf
August 23, 2013 - bleeding risk, our roundtable experts concluded that
more research is needed into specific risks … stated a
measure of “% reduction” and it’s not clear if this
point estimate (95% CI) is calculated on relative … (95% CIs) are
reported as HRs, however, Connolly et al 2009
reported RE-LY efficacy endpoints as relative … We now clarify that the % reduction was a relative risk reduction. … We have highlighted the risks associated
with use of dabigatran re: risk of MI as well as dyspepsia
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_disposition-comments.pdf
March 10, 2010 - Introduction Women need to understand what their own risks are of death as a result
of breast cancer … for that subgroup, or
difference in relative risk. … We agree, sorting out baseline risks from elevated relative risks is
confusing. … We have included relative risk estimates for each
subgroup in the text when they are calculated. … (older age) versus relative risk
of treatment.
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/dot-plots-methods.pdf
October 01, 2021 - risk with 95 percent confidence intervals as
well as the absolute rates in each arm. … risks) in the same format as the dot plots. … risk and 95 percent
confidence interval. … and control groups along with the proportion of patients who experienced an
outcome in each group, relative … risk;
SOE = strength of evidence
Figure 2.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-therapies-update_executive.pdf
December 01, 2014 - Institutes
of Health (NIH) State-of-the Science Conference in
December 2011 to better understand the risks … For KQ 1, we summarize and discuss comparative
risks, benefits, and outcomes of therapies. … KQ 1: Comparative Risks and Benefits of
Therapies for Clinically Localized Prostate Cancer
Eight RCTs … in 16 publications addressed comparative
risks and benefits for various therapies. … prostatectomy;
RPP = radical perineal prostatectomy; RRP = radical retropubic prostatectomy; RR = relative
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effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-37-opiod-use-adults-comments.pdf
November 03, 2020 - Such
comparisons are not addressing Q2 or telling you
about risks among opioid types. … of opioid prescribing, including risks for
overdose, suicide, and death. … are fundamentally different than risks associated
with prevalent use. … studies that looked at prior
or early postoperative opioid use
found mostly strong associations
(e.g., relative … Any discussion of
opioid risks should also include the risks of rapid,
inappropriate, forced tapering
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_disposition-comments.pdf
March 01, 2012 - would provide a more
accurate value than an estimation from relative risks. … Peer Reviewer #1 Results 1.Provide relative risks and confidence intervals for
studies included. … Calculation of relative risk and
odds ratio, whether pooled or not, was conducted using the
raw numerical … The individual study
relative risk or odds ratio (depending on the pooled effect)
along with its confidence … When only
one trial was available we report the calculated relative risk or
odds ratio with the confidence