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Total Results: 2,110 records

Showing results for "risks".

441. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/undescended-testicle_research-protocol.pdf
     September 02, 2011 - magnetic resonance angiography, which requires sedation or anesthesia and is thus not without immediate risks … An estimated 10 percent of all testicular tumors develop from an undescended testis, 9 and the relative … risk of incidence of a testicular tumor is about 40 times greater in men with cryptorchidism when … Although many clinicians advocate early orchiopexy to reduce the risk of testicular cancer associated … Assessing risk of bias in included studies. In: Higgins JPT, Green S, eds.

442. Ptsd-Adults-Trauma-Interventions Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adults-trauma-interventions_research-protocol.pdf
     November 08, 2012 - KQ 4: For adults exposed to psychological trauma, what are the absolute risks or comparative risks of … groups, and sex) o Populations with psychiatric comorbidities o Populations with different personal risks … KQ 4 addresses the absolute and comparative risks of harms and adverse events from these interventions … The “Population at risk…” box was revised as follows: “Population at risk: Adults exposed to psychological … The “Population at risk…” box was revised as follows: “Population at risk: Adults exposed to psychological

443. Disposition of Comments Report for Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
     September 25, 2013 - Including data available only in abstract form has inherent risks such as numerical errors and misinterpretation … Section Comment Response Peer Reviewers 2, 3, 4 Methods Despite imprecision, the lower bound of the relative … reduction versus increased bleeding risk. … The authors should include a summary of the comparative risks of genetic vs. nongenetic factors routinely … Additionally, it would be appropriate to frame the relative risks between CYP2C19 genotypes against

444. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/insulin-blood-sugar-2010_research-protocol.pdf
     January 01, 2010 - www.effectivehealthcare.ahrq.gov Published Online: June 2, 2011 Importance of Tight Glycemic Control and Associated Risks … of diabetic complications, it is not without risks. … The benefits and risks of intensive insulin therapy with CSII, therefore, have not clearly been established … Poor (high risk of bias). … and Laird formula. 29 For dichotomous outcomes, we will calculate a pooled effect estimate of the relative

445. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests_executive.pdf
     February 01, 2006 - For women with relevant demographic risk factors (e.g., age, family history) and clinical risk factors … For women at this average level of risk of cancer after an abnormal mammogram, based upon the tests’ … the risk that she has cancer even if the test is negative. … acceptable level of risk for a diagnostic test to reliably preclude biopsy, none of these tests was … sufficiently accurate to replace biopsy for women at average risk of breast cancer.

446. Nutrition as Prevention for Improved Cancer Outcomes (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/improved-cancer-outcomes-protocol_0.pdf
     December 01, 2021 - with cancer, with estimates ranging between 25 to 80 percent across patient populations.7-9 However, risk … pre-existing conditions (e.g., obesity), among other factors.8,10 Further, many factors may increase risk … All eligible studies addressing KQ 1-4 will be assessed for risk of bias. … reviewers will assess risk of bias of eligible studies. … Reviewers will consult to reconcile discrepancies in overall risk of bias.

447. Suppl-2-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/suppl-2-user-guide-to-ocer_130129.pdf
     January 01, 2011 - of experiencing the outcome in the two groups at the time of treatment assignment is equal to the risk … In addition, because the outcome risks in the subpopulations are equivalent at the time treatment is … assigned, the observed risk difference between the treatment groups can be attributed to treatment … Using the risk difference scale, this means that the conditional risk difference can be used to estimate … the marginal causal risk difference (Pr[Y=1|A=1] - Pr[Y=1|A=0]) = (Pr[Ya=1=1]- (Pr[Ya=0=1]).

448. Tympanostomy Tubes in Children With Otitis Media (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-executive-170523.pdf
     May 01, 2017 - difference in cumulative hazard of recurrent AOM or in efficacy, defined as one minus the adjusted relative … Risk of bias for various outcomes in high risk populations was rated as high. … Risk of bias was rated moderate overall. … Tympanostomy tube outcomes in children at risk and not at-risk for developmental delays. … Panel 1: Epidemiology, natural history, and risk factors.

449. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-bone-fracture_research-protocol.pdf
     May 14, 2010 - KQ2: How does fracture reduction resulting from treatments vary between individuals with different risks … c) What are the effects of adherence and persistence on the risk of fractures? … for OP fractures Health Outcomes: Change in fracture risk (KQ1,2) Change in BMD (KQ5[?] … KQ5 assesses the ability of risk predictors to identify people who are at greater risk of OP fracture … Assessment of fracture risk. Osteoporos Int 2005;16(6):581-9. 6.

450. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/tympanostomy-tubes_research-protocol.pdf
     November 16, 2015 - There is interest in comparative effectiveness of tympanostomy tubes in high-risk and at-risk populations … Many randomized trials are relatively small, limiting their ability to define risks of less common harms … For RCTs, we will use the Cochrane risk of bias tool 22, which asks about risk of selection bias, performance … Tympanostomy tube outcomes in children at-risk and not at-risk for developmental delays. … Panel 1: Epidemiology, natural history, and risk factors.

451. S116 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s116.pdf
     October 01, 2007 - This model yielded adjusted estimates of risk differences. … using more hazardous treatments, the bias would be conservative, tending to narrow the differ- ence in risks … †Prevalence of risk factor among atypical users minus prevalence of risk factor among conventional users … Risk of death in elderly users of conventional vs. atypical antipsychotic medications. … Benzodiazepines of long and short elimination half-life and the risk of hip fracture.

452. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pulmonary_hi_impact.pdf
     April 01, 2012 - However, experts also cited the small evidence base, lack of long-term data, serious risks associated … suitable for BT because several other respiratory complications are associated with an increased risk … One expert with a health systems perspective also cited the altered risk-benefit ratio of BT compared … Although the experts expected many patients with severe asthma to request the surgery, serious risks … However, the experts cited the small evidence base, lack of long-term data, serious risks associated

453. Management of Suspected Opioid Overdose With Naloxone by Emergency Medical Services Personnel - Executive Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-193-naloxone-executive-summary.pdf
     November 01, 2017 - Risk of Bias Assessment of Individual Studies We assessed risk of bias of included studies using … Effectiveness Reviews.34 We adapted criteria for assessing risk of bias from the U.S. … Studies were rated as “low risk of bias,” “medium risk of bias,” or “high risk of bias” based on the … [CI] 0.3 to 1.5), mean response time (8.0 vs. 7.9 minutes), or agitation/violence (6.0% vs. 7.9%, relative … risk [RR] 0.77, 95% CI 0.25 to 2.3).

454. Methods Guide for Medical Test Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-bias_methods.pdf
     July 01, 2012 - Methods Guide for Medical Test Reviews 5-1 Chapter 5 Assessing Risk of Bias as a Domain of Quality … Risk: Low/High/Unclear *Questions related to assessing applicability were excluded here. … Summarizing risk of bias based on several outcomes within a study is not recommended. … Systematic review: family history in risk assessment for common diseases. … Assessing risk of bias as a domain of quality in medical test studies.

455. Disposition of Comments Report for Evaluation and Treatment of Cryptorchidism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_disposition-comments.pdf
     December 11, 2012 - Peer Reviewer #6 Introduction Page 29, Line 54: Page 1--next to last line, the reference that the relative … Peer Reviewer #7 Introduction Page 29, Line 54: "relative risk of testis CA after UDT is 40X gen population … I think a more complete discussion of malignancy risks should be included and would fit under KQ 4, … population most likely will require sedation or anesthesia, which has the potential for significant risks … Pettersson et al- NEJM- risk of testis ca with UDT P.

456. Prostate-Cancer-Therapies-Update Consumer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_consumer.pdf
     January 01, 2016 - � Men aged 50 years or older have a higher risk of prostate cancer. … � The risk of prostate cancer is higher for men with a history of prostate cancer in their family. … Your risk level can help you and your doctor decide what treatment may be best for you. … Risk Level* PSA Level Gleason Score T-Score Low risk† 10 or less 6 or less T1–T2a Medium risk†† 10 … These may include your risk level, your age, and any other health problems.

457. Technical Brief 13: Gene Expression Profiling for Predicting Outcomes in Stage II Colon Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_technical-brief.pdf
     December 01, 2012 - Identifying the individuals in whom the potential benefits of chemotherapy outweigh the risks is challenging … On the other hand, introducing routine testing without a clear understanding of benefits and risks could … obtained with standard risk factors? … The discussion with a patient about the benefits and risks of adjuvant chemotherapy usually occurs 3 … use of the GEP assay for treatment management improve net health outcome (considering benefits and risks

458. Dementia-Agitation-Aggression Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/dementia-agitation-aggression_executive.pdf
     March 01, 2016 - aggression involves at least one other person (the target of the aggression) and can represent real risks … handling of incomplete data); reporting bias (selective reporting of outcomes or analyses); and other risks … to reduce the use of antipsychotic medications in people with dementia should continue, given the risks … Evidence about the risks associated with antipsychotic use in older adults is mounting. … Development of the risk appraisal measure: a brief screen to identify risk areas and guide interventions

459. Dietary-Supplements Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_executive.pdf
     April 01, 2012 - heart failure or other cardiovascular disease use dietary supplementation and are thus placed at risk … of bias for the study as low, moderate, or high risk, and a second reviewer independently verified … Relative risk (RR) and post-treatment mean differences (MDs) were meta-analyzed using the DerSimonian … international normalized ratio; LDL-C = low-density lipoprotein-cholesterol; MD = mean difference; RR = relative … They recruited healthy subjects, or subjects with CHD or risk factors for CHD.

460. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cognitive-decline_executive.pdf
     March 01, 2017 - Although many putative risk factors have been identified, the challenge is to identify any interventions … Interventions represent one way to establish the veracity of risk factors. … Results were extracted only from studies assessed as having low to moderate risk of bias. … not the risk of CATD or of a combined outcome of MCI or CATD compared to placebo … Raloxifene may reduce risk of MCI.