-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-choosing-outcomes.ppt
June 01, 2012 - Outcomes may affect the balance of test benefits/risks. … These outcomes may affect the balance between the benefits and risks of a test. … Low risk for
preterm delivery
Average risk for preterm delivery
High risk for preterm delivery … , including a procedural
risk that computerized tomography does not have. … In this example, the comparison test carries comparable or greater risks.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/masks-surveillance-2-report.pdf
October 01, 2020 - MERS-
CoV
Community settings: Masks
(type not specified) are possibly
associated with decreased risk … in moderate or
higher risk settings. … versus cloth
masks in moderate or higher
risk settings. … in lower risk
(outpatient) settings. … One new observational study1 on mask use and
versus no use risk of SARS-CoV-2 infection in healthcare
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading-quiz.ppt
May 29, 2025 - Individual studies are rated for their internal validity or risk of bias. … Only one of these is quality (risk of bias) of the individual studies. … Risk of bias, consistency, directness, and precision
Risk of bias, consistency, directness, precision … The four required domains are risk of bias (i.e., quality ratings for individual studies with respect … The four required domains are risk of bias, consistency, directness, and precision.
-
effectivehealthcare.ahrq.gov/sites/default/files/grading-quiz.ppt
May 29, 2025 - Individual studies are rated for their internal validity or risk of bias. … Only one of these is quality (risk of bias) of the individual studies. … Risk of bias, consistency, directness, and precision
Risk of bias, consistency, directness, precision … The four required domains are risk of bias (i.e., quality ratings for individual studies with respect … The four required domains are risk of bias, consistency, directness, and precision.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/partial-breast-irradiation-disposition-comments.pdf
January 31, 2023 - Can risks/benefits be used
instead? … Risk/benefit
terminology may
imply that we did
some sort of risk
benefit analysis. … The findings were
generated from
subgroup
analyses and
suffer higher risk
of bias. … of recurrence (with all the caveats of risk & benefit & patient preference discussed). … agree with the AHRQ
review that there is currently insufficient data to draw conclusions about the risks
-
effectivehealthcare.ahrq.gov/sites/default/files/prostate-cancer-therapies-summary.pdf
September 01, 2020 - Effects may not vary by patient or tumor risk factors. … Results may not vary
by patient or tumor risk characteristics. … Retrospective observational
studies often had a high risk of bias. … Age and tumor risk category may be important effect modifiers. … reduction
due to RP may be limited to intermediate-risk disease or age <65 years.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/research-protocol-osteoporosis_2.pdf
October 05, 2018 - Because risks of hip, vertebral
and other fractures rise steeply with age, and because the population … of infection, teriparatide
increases risk of hypercalcemia, raloxifene increases risk of hot flashes … [e.g., past fracture, BMD or fracture risk
calculator]). … All eligible studies first will be assessed for risk of bias (see IV.E. for details of risk of
bias … assess each eligible study for risk of bias in its
design, analysis and reporting.[18] Risk of bias
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-surgical-report-cards.pdf
November 01, 2023 - The
National Veterans Administration Surgical
Risk Study: risk adjustment for the
comparative assessment … Using risk-adjusted outcomes to
assess clinical practice: an overview of
issues pertaining to risk adjustment … The National Veterans Administration Surgical Risk
Study: risk adjustment for the comparative assessment … 30-day mortality (relative risk
[RR] 0.96, 95% CI, 0.89–
1.03), serious complications
(RR 0.96, 95% … Data Bank; O/E = observed vs expected ratio; PDSA = Plan Do Study Act; PE = pulmonary embolism; RR = relative
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - (Low)
RCTs of early RA treatment
showed no difference in risk of
serious infection or risk of
malignancy … Biologics neither decreased nor increased
cardiovascular risks in the elderly. … Risk did not differ
significantly by
specific drug. … MTX not
associated with
reduced risk. … Biologics neither decreased nor increased
cardiovascular risks in the elderly.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - (Low)
RCTs of early RA treatment
showed no difference in risk of
serious infection or risk of
malignancy … Biologics neither decreased nor increased
cardiovascular risks in the elderly. … Risk did not differ
significantly by
specific drug. … MTX not
associated with
reduced risk. … Biologics neither decreased nor increased
cardiovascular risks in the elderly.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-executive-summary-2023-update.pdf
January 01, 2023 - There may be a large increased
risk of dizziness and sedation and a moderate increased risk of nausea … of sedation, and potential increased risk of
nausea versus placebo. … Synthetic THC is probably associated with a large
increased risk of dizziness. … -point scale
• SMD >0.8
• RR/OR ≥2.0
Abbreviations: MD = mean difference; OR = odds ratio; RR = relative … risk; SMD = standardized mean difference.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-draft-appendix-d2.xlsx
January 01, 2024 - …Three treatment groups were defined based on risk of seminal vesicle involvement: group 1 had a risk … of 10% or less; group 2 had a risk of 10–25%; group 3 had a risk of higher than 25%. … of seminal vesicle involvement: group 1 had a risk of ≤10%; group 2 had a risk of 10–25%; group 3 had … a risk of >25%. … Prostate + Seminal Vesicles SBRT,IGRT,VMAT Yes ADT (6 mo intermediate risk, 18 mo high risk) Yes Yes
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_executive.pdf
April 01, 2013 - Risk-of-Bias Assessment of Individual Studies
To assess the risk of bias (internal validity) of studies … fluoxetine,
paroxetine, and sertraline—most of the evidence was
insufficient to determine whether risks … Findings were insufficient to determine whether the risks
of other adverse events are increased. … approaches are more effective for victims
of particular types of trauma or to determine comparative
risks … The psychological
risks of Vietnam for U.S. veterans: a revisit with new data and
methods.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research-protocol.pdf
September 02, 2016 - this methodology report is to examine the feasibility and additional
utility—in terms of impact on risk … For newly found studies,
we will record additional data and assess their risk of bias. … We will apply the same risk of bias
assessments as in the original review. … There is interest in comparative effectiveness of tympanostomy tubes in
high-risk and at-risk populations … Many randomized trials are relatively small, limiting their ability to
define risks of less common harms
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_disposition-comments.pdf
November 27, 2012 - perioperative mortality (the
largest series of patients with
HCV infection found no deaths)
as well as risks … of CV events,
and large risks of long-term
impotence/ incontinence). … These risks should be noted in the background section.
Thank you for your comment. … testing (if treatment is effective) unless there is a compelling cost reason to avoid it or the
risks … the limited time available in
primary care visits and the awkwardness of discussing the behavioral risks
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_research-protocol.pdf
October 01, 2013 - or both), duration, and type of intravascular fluids used to
prevent CIN15; and d) the comparative risks … The IA route may confer more risk than the IV use,5, 20, 21 but that risk may
be confounded by the pre-existing … This emphasizes the
need for a comprehensive evidence-based synthesis of risks for patients undergoing … ● High or moderate risk patients (as defined by clinical or demographic risk
factors such as age … Assessment of Methodological Risk of Bias of Individual Studies – The
assessment of risk of bias will
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-urinary-retention_research.pdf
September 01, 2014 - Intent
To
Treat
Groups
Similar at
Baseline
Other
Risks
of Bias
Overall Risk of
Bias … group
(19/29) no longer needed catheterization compared to the delayed implant group (2/22) with a
relative … Insufficient
PVR (ml), adjusted MD -135 [95%CI -233 to -37] Moderate Indirect Precise Single study Low
RR = relative … 1068 [95% CI --1493to -643 ] Moderate Indirect Precise Single study Low
SR=systematic review; RR = relative … 95% CI -47 to 0.63] Moderate Indirect Precise Single study Low
Single study = not applicable; RR = relative
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
January 09, 2020 - In addition to effectiveness, decisionmakers need information on potential adverse risks, and
special … Frequent use of acute pharmacologic treatments carries the risk of medication
overuse headache (MOH) … Assessment of the Risk of Bias of Individual Studies: We will evaluate the risk of bias of
the included … studies (in a particular comparison) have high
or unclear risk of bias. … RoB 2: a revised tool for assessing risk of bias
in randomised trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-disease-medicine_research-protocol.pdf
November 01, 2010 - and burden is decreased by competing risks such as
short life expectancy. … Studies will be rated as Good (low
risk of bias), Fair, or Poor (high risk of bias) as described in … Chronic kidney disease and
the risks of death, cardiovascular events, and hospitalization. … Renal function and risk of hip and vertebral fractures in older women. … CKD
and risk of hospitalization and death with pneumonia.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-1.pdf
June 01, 2022 - risk Low risk Low risk
Ashina, 20213 High risk Moderate risk Low risk High risk Low risk Low risk … Moderate risk Low risk Low risk Low risk Low risk
Hodgson, 20216 Low risk Low risk Low risk Low risk … Low risk Low risk
Hokenek, 20217 Low risk Low risk Low risk Low risk Low risk Moderate risk
Kandil … Low risk Low risk Low risk Low risk
Lipton, 202110 High risk High risk Low risk Low risk Low risk Low … Abbreviations: AE = adverse event; CI = confidence interval; mg = milligram; N/A = not applicable; RR = relative