-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-function_research-protocol.pdf
June 13, 2013 - This may subject patients to unnecessary
coronary angiography and its potential risks (i.e., contrast … using traditional risk factors such as the Framingham Risk Score. … using
traditional risk factors such as the Framingham Risk
Score. … • Poor (high risk of bias). … DerSimonian and Laird formula.30 For dichotomous
outcomes, we will calculate a pooled effect estimate of the relative
-
effectivehealthcare.ahrq.gov/sites/default/files/coronary-artery-disease-testing_executive.pdf
March 01, 2011 - (ACS), although its invasive nature makes it less ideal
in many patients because of its associated risks … harms, adverse reactions to drugs for stress tests,
vascular complications (e.g., stroke)
Consequences/risks … related to harms of testing (e.g., adverse reaction or allergy
to contrast or stress agents) and risks … high risk, and mixed risk (or
pretest risk not reported). … In addition,
potential harm from use of invasive treatments (which
carry specific risks) if clinical
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_11-user-guide-to-ocer_130129.pdf
January 03, 2012 - asked in a study, as
excluding prevalent users might omit long-term
users (which could overlook risks … of
death among the patients treated with aprotinin
(estimates ranged from a relative risk of 1.32 … Sensitivity Analysis
[propensity score] to a relative risk of 1.64
[traditional regression analysis … quickly calcification progresses once the process
has begun.20
First, a model is developed for the relative … 11.2 plots the combination of the odds ratio
between the exposure and the confounder (OREC)
and the relative
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
September 01, 2014 - For quality, see section on risk
of bias.
b. … • EUS-FNA risks are due to the physical invasiveness
of the procedure and primarily involve pancreatitis … • MRI risks mainly involve adverse reactions to contrast
media. … EUS-FNA risks are due to the
physical invasiveness of this procedure and primarily
16
involve pancreatitis … four imaging studies are not equally available at
all institutions, and each study has its associated risks
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-treatment_disposition-comments.pdf
April 01, 2012 - United States.1
Pfizer supports the effort to ensure that credible and appropriate
evidence on the risks … associated with taking glaucoma medication
and how these risks are directly linked to specific patient … Thus, in Key Question 6, we recommend that
AHRQ comprehensively evaluate the risks and harms associated … with OAG treatment by subpopulation
These risks were evaluated as part of KQ6. … Public
comment/
Pfizer
Methods In addition, we suggest that AHRQ assess the severity of the risks
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/patient-participant-generated-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - with traditional registries, participants need to be informed clearly and transparently about the
risks … of IRB reliance relationships in the context of PGRs
is encouraged by PCORI’s PCORnet.90 Potential risks … A
community-engaged approach to
quantifying caregiver preferences for the
benefits and risks of emerging … /sha
ring-clinical-trial-data-maximizing-benefits-
minimizing-risk. … Participant-driven research:
rich opportunities and real risks.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-prognostic.ppt
June 01, 2012 - not experience the outcome of interest
Statistically significant associations (odds/hazard ratios, relative … risks) merely indicate that more definitive evaluation of a new predictor is warranted. … Statistically significant associations such as HRs, relative risk, or ORs ratios indicate only that it … Assessing the value of risk predictions by using risk stratification tables. … Assessing the value of risk predictions by using risk stratification tables.
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-prognostic.ppt
June 01, 2012 - not experience the outcome of interest
Statistically significant associations (odds/hazard ratios, relative … risks) merely indicate that more definitive evaluation of a new predictor is warranted. … Statistically significant associations such as HRs, relative risk, or ORs ratios indicate only that it … Assessing the value of risk predictions by using risk stratification tables. … Assessing the value of risk predictions by using risk stratification tables.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
September 01, 2014 - of cancer, or did not provide information on baseline
risk. … Assessment of Risk of Bias
We assessed the risk of bias for each individual study
following the Methods … Results are based on the model with risk group as a covariate. … of vasovagal reactions;
however, results were reported in a way that precluded
quantitation of the relative … risk.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-diagnosis-future_research.pdf
February 01, 2012 - stakeholders’ discussions
centered on the anecdotal nature of the evidence regarding perioperative risks … Most of the discussion centered on the anecdotal nature of the evidence regarding the
perioperative risks … The effectiveness of perioperative care was discussed as well as
strategies for mitigating risks such … We set the range of relative risk reduction between 0.6 and 0.8, as the study
reported a relative risk … power of 90 percent,
the required total sample size (1:1 ratio in a two-arm RCT) for each value of relative
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-protocol.pdf
February 01, 2023 - risk of bias domains defined in the AHRQ Methods Guide49, 50 and using an adapted
version of the Risk … We will rate the risk of bias for each study by domain and overall, as low, moderate,
or high risk of … Two independent reviewers will assess the risk of bias for each primary
study. … outcomes; analytic
methods including adjustment for confounding factors; and results (e.g., absolute and relative … risks of the outcome) favoring those that are adjusted for potential confounders rather than
unadjusted
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-protocol-amendment.pdf
February 03, 2025 - risk of bias domains defined in the AHRQ Methods Guide49, 50 and using an adapted
version of the Risk … We will rate the risk of bias for each study by domain and overall, as low, moderate,
or high risk of … Two independent reviewers will assess the risk of bias for each primary
study. … outcomes; analytic
methods including adjustment for confounding factors; and results (e.g., absolute and relative … risks of the outcome) favoring those that are adjusted for potential confounders rather than
unadjusted
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-259-partial-breast-irradiation-executive-summary.pdf
January 01, 2023 - with 15-20 treatments delivered over three to four weeks.2, 3 Although
WBI successfully reduces the risk … Analysis of patterns of recurrence and pathology findings have supported that
the area at highest risk … This highlights the need to investigate outcomes of
PBI among patients with adverse risk factors. … These advancements
result in improved dose homogeneity that may lower the risk for adverse events. … fractionation schedule, and planning parameters are
recognized as critically important to understand the risks
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-supplementary-app-d.xlsx
January 01, 2023 - There is low risk of bias in domain 2. … There is low risk of bias in domain 3. … There is high risk of bias in domain 5. Overall, this study has high risk of bias. … There is low risk of bias in domain 2. … There is high risk of bias in domain 5. Overall, this study has high risk of bias.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-monitoring-systems-rapid-review.pdf
December 01, 2024 - They found that the relative risk of a major adverse event
was statistically lower (p<0.001) in the … Australian Between the Flags system) and
found no significant change in response to the intervention (relative … of death 30 days post-alert was significantly reduced
(relative risk 0.84, 95% CI 0.78 to 0.90, p<0.001 … increase in transfers (p=0.00154 and p=0.0356), two reported
statistically significant decreases (relative … assessment”[tiab] OR
“risk assessment”[mh] OR “risk classification”[tiab] OR “risk category”[tiab]
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_surveillance.pdf
July 01, 2012 - Pfizer NOT
pursuing FDA approval) has
come out that shows that a
0.5 mg dose appears to
reduce the risks … from medications to
reduce risk of breast cancer? … Nine risk
stratification
models that
predict an
individual’s risk
for developing
breast cancer … Incidence
rates/risks of
gynecologic
conditions
Median 81
month follow-
up reported
Good/Good … Nine risk stratification models that
predict an individual’s risk for
developing breast cancer have
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-evidence-summary-2022-update_0.pdf
January 01, 2022 - There may be a large increased risk of dizziness and sedation and a moderate
increased risk of nausea … of sedation, and potential
increased risk of nausea versus placebo. … Synthetic THC is probably associated
with a large increased risk of dizziness. … -point scale
• SMD >0.8
• RR/OR ≥2.0
Abbreviations: MD = mean difference; OR = odds ratio; RR = relative … risk; SMD = standardized mean difference.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-221-copd-comments_0.pdf
October 11, 2019 - risk) for binary outcomes? … Why not a relative
risk? … There are pros and cons for odds ratio versus relative
risk and there is no preferred way for sure. … Odds ratio has
better statistical properties than relative risk such as
being symmetrical when converting … We used the Cochrane Risk of Bias tool.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol.pdf
January 01, 2024 - We will assess the risk of bias for
RCTs using the Cochrane Risk of Bias 2 (ROB2) and NRSIs (including … As different outcomes and results from the same study may reflect different risks of
bias (e.g., objective … yields a higher SOE rating
than a set of studies at moderate or high risk of bias. … of
bias is comparable to an RCT at low risk of bias. … RoB 2: a revised tool for assessing risk of bias in
randomised trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-draft-appendix-d1.xlsx
January 01, 2024 - group Intervention Group NCCN risk group Control group NCCN Risk group Cancer stage overall Cancer … risk factors stage T3aN0M0, Gleason score ≥7 (4+3), or PSA >20 ng/mL. … prostate cancer; high-risk with pelvic nodal involvement risk <15% by updated Partin Tables and negative … All patients with high-risk disease were prescribed ADT for 2 years. … (LR), favorable-intermediate risk (FIR), unfavorable intermediate risk (UIR) and high risk (HR) as per