-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_executive.pdf
September 01, 2011 - alpha,
including etanercept, infliximab, and adalimumab, due
to concerns about potential increased risk … (f) Because of the known risks associated with
DMARDs, we focused primarily on serious infections
and … adverse events considered included
mortality, hepatitis, bone marrow suppression, nausea
or vomiting, and risks … Randomized discontinuation trials
have helped to define the risk of flare in patients who
respond to … One solution to
evaluating risk would be to develop registries for
DMARDs when used for childhood JIA
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_research-protocol.pdf
December 06, 2010 - Many questions remain about the
risks of these agents across a spectrum of adverse events—from relatively … Finally, very little is known about the
benefits or risks of these drugs AMONG different patient subgroups
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-reviews-end-user_white-paper.pdf
April 01, 2016 - (what approaches could be altered to increase
efficiencies, what are they willing to accept), and risks … Related to the above issue, KIs commented on the risk that a rapid product might give
the wrong … Producers need to ensure that rapid products
use transparent methods that communicate potential risks … what pieces or methods could be altered to increase efficiencies, what
are they willing to accept), risks … What do you see as potential risks of using different types of synthesis products, or
information generated
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-stone-prevention_research-protocol.pdf
June 15, 2011 - RevMan) version 5.0
software.
33
Random effects models will be used to generate pooled estimates of relative … risks and
95 percent confidence intervals. … The risk of bias—based on
study design and conduct—will be rated low, medium, or high. … Prospective study of beverage use and the risk of
kidney stones. … History of kidney stones as a possible risk
factor for chronic kidney disease.
-
effectivehealthcare.ahrq.gov/sites/default/files/interactive_media_glasgow_presentation.pdf
January 01, 2009 - Knowledge
• ADVISE:
o Provide
specific
o Information
about
o Health
risks
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/worker-safety-wellness-protocol.pdf
October 26, 2024 - Assessment of Risk of Bias in Individual Studies: We will evaluate each study for risk of bias
and methodological … As reported data allow, we will primarily evaluate relative risks (RRs) for dichotomous
outcomes, net … Risks Related To
Fluoroscopy Radiation Associated With Electrophysiology Procedures. … Blood and body fluid exposure risks among
health care workers: results from the Duke Health and Safety … Risk of Bias 2 (RoB 2) tool | Cochrane Methods Available from: https://methods.cochrane.org/risk-bias
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
February 01, 2012 - Do the effectiveness and risks of FGAs and SGAs
vary in differing subpopulations including:
• Sex? … The
two NRCTs had a high risk of bias. … prospective cohort study; RCS = retrospective cohort
study; RCT = randomized controlled trial; RR = relative … first-generation antipsychotic; PCS = prospective cohort study; RCT = randomized
controlled trial; RR = relative … Treatment benefits and risks were examined most
frequently for schizophrenia; the evidence for
conditions
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cesarean-birth-2010_executive.pdf
January 01, 2010 - reduce fear
of labor, education about how to push in labor, and
preemptive management of specific risks … of using a partogram
to graph labor progress along with active management to
augment labor (7.4%, relative … We did not include studies
focused only on high-risk populations. … Previous cesarean
delivery and risks of placenta previa and placental abruption. … Physician
contribution to a cesarean delivery risk model.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-2.pdf
April 01, 2022 - mitigation
strategies, dose-dependent risks of opioids, and management of opioid use disorder, all … In patients with chronic pain, what are the risks of opioids versus placebo
or no opioid on: (1) opioid … In patients with chronic pain, what are the comparative risks of opioids
versus nonopioid therapies … In patients with chronic pain, what are the comparative risks of opioids
plus nonopioid interventions … Experiencing the Risks of
Overutilizing Opioids Among Patients With
Non-Tumor Chronic Pain in Ambulant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_executive.pdf
August 01, 2016 - It found significant associations between higher
plasma DPA and lower risks of all-cause and CVD death … ,
which included people who may have other nutrition
deficiencies that may affect chronic disease risks … or associations of higher n-3 FA intake or biomarker levels and
lower cardiovascular disease (CVD) risks … Report of the Joint FAO/WHO Expert Consultation on
the Risks and Benefits of Fish Consumption. … Seafood Choices: Balancing Benefits
and Risks. Nesheim MC, Yaktine AL, editors.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatigue-sleepiness-protocol.pdf
July 01, 2023 - Patient safety risks due to fatigue and sleepiness of
healthcare workers were not addressed in MHS … Fatigue Risk Management in the Workplace. … How effective are Fatigue Risk Management
Systems (FRMS)? A review. … The Cochrane Collaboration's tool for assessing risk
of bias in randomised trials. … ROBINS-I: a tool for assessing risk of bias in non-
randomised studies of interventions.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-257-antenatal-care-evidence-summary.pdf
June 01, 2022 - overcrowding (of
clinics), may increase clinic time available to be directed to patients
with high-risk … The RCTs were mostly at low risk of bias, except
that studies could not blind the intervention (one … The
survey was at low risk of bias. The number of televisits ranged from one to five. … increased risks (e.g., stressors). … The NRCSs were almost all unadjusted and thus subject to high
risk of bias.
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
January 01, 2015 - strength of evidence that sulfonylurea
monotherapy was associated with a 50-percent to
70-percent higher relative … difference; RR = relative risk; SOE =
strength of evidence. … Sulfonylurea
monotherapy was associated with a 50-percent to
70-percent higher relative risk of cardiovascular … These other
monotherapies’ effects on body weight vary, as do their
risks, such as congestive heart … medications on weight, hypoglycemia, and
gastrointestinal and other side effects; tolerance of
unknown risks
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-adults-executive-130408.pdf
April 01, 2013 - Using Meta-Analyst and STATA® software, we calculated
the relative risk and absolute risk difference … We evaluated the
strength of the association, defining a priori a large effect
when relative risk was … >2 and a very large effect when
relative risk was >5.25 We defined low magnitude of the
effect when … relative risk was significant but <2. … Our review
demonstrated that a relative risk of adverse effects with
onabotulinumtoxin A was lower
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-protocol.pdf
April 17, 2024 - Assessment of Methodological Risk of Bias of Individual Studies: We define the risk of bias
as the risk … We will assess the risk of
bias for each included study using the Cochrane Risk of Bias 2 (ROB2) tool … category, and risk of bias rating. … >0.8
RR/OR/HR ≥2.0
Abbreviations: HR = hazard ratio; MD = mean difference; OR = odds ratio; RR = relative … risk; SMD = standardized mean difference.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dental-immunodeficiency-virus-rapid-response.pdf
May 01, 2025 - risk of bias. … and Human
Services similarly recommend modifications for complex cases, such as identified bleeding risks … For
example, the Saveetha Dental College guidelines emphasize counseling on oral hygiene, lifestyle
risks … continued
monitoring for oral lesions and manifestations of HIV, and providing
education on lifestyle risks … of bias
RR Relative risk
SD Standard deviation
SME Subject matter expert
SR Systematic review
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ped-mindfulness-protocol-amendment.pdf
February 05, 2025 - Assessment of Methodological Risk of Bias of Individual Studies: We define the risk of bias
as the risk … We will assess the risk of
bias for each included study using the Cochrane Risk of Bias 2 (ROB2) tool … 100-point scale
SMD >0.8
RR/OR ≥2.0
Abbreviations: MD = mean difference; OR = odds ratio; RR = relative … risk; SMD = standardized mean difference. … Strategies; PedsQL = Pediatric Quality of Life Inventory; RADS =
Reynolds Adolescent Depression Scale; RR = relative
-
effectivehealthcare.ahrq.gov/sites/default/files/coronary-artery-disease-testing_disposition-comments.pdf
March 29, 2016 - Reviewer 2 Methods Analyses was performed in subgroups of patients stratified
by different pre-test risks … But only the pre-test risks reported by authors
of the studies were used for stratification. … The review team spent substantial time
considering ways of standardizing the
findings on pre-test risks … is harm in itself
if not associated with demonstrable clinical benefit as these
entail real, known risks … (unlike radiation in which the risks are
theoretical and not known).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-disposition.pdf
June 22, 2017 - have added low strength of
evidence findings regarding LMWH
vs. aspirin in THR patients (similar
risks … However, the relative
risks of surgical site bleeding are 6.38
(95% CI 4.56-8.92) for LMWH vs ASA, … from LMWHs to FXaIs and
found a significant increase in total
wound complications (LMWH vs FXaI
relative … Therefore, FXaIs have a higher risk of
wound complications than LMWH and
LMWHs have the highest relative … increase the risk of a VTE event to a
level that the risks of surgical site
bleeding and death are
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-review-masks-prevention-covid-version-2.pdf
December 01, 2021 - of infection with SARS-CoV-2, 15 studies on risk
of infection with SARS-CoV-1, and one study on risk … in risk of clinical
respiratory illness. … Risk
factors for SARS infection within hospitals in Hanoi,
Vietnam. … incidence of SARS-CoV-2 infection by use of personal protective equipment (PPE) by
health workers
Relative … Risk factors for SARS infection within
hospitals in Hanoi, Vietnam.