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  1. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_executive.pdf
    September 01, 2011 - alpha, including etanercept, infliximab, and adalimumab, due to concerns about potential increased risk … (f) Because of the known risks associated with DMARDs, we focused primarily on serious infections and … adverse events considered included mortality, hepatitis, bone marrow suppression, nausea or vomiting, and risks … Randomized discontinuation trials have helped to define the risk of flare in patients who respond to … One solution to evaluating risk would be to develop registries for DMARDs when used for childhood JIA
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_research-protocol.pdf
    December 06, 2010 - Many questions remain about the risks of these agents across a spectrum of adverse events—from relatively … Finally, very little is known about the benefits or risks of these drugs AMONG different patient subgroups
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-reviews-end-user_white-paper.pdf
    April 01, 2016 - (what approaches could be altered to increase efficiencies, what are they willing to accept), and risks …  Related to the above issue, KIs commented on the risk that a rapid product might give the wrong … Producers need to ensure that rapid products use transparent methods that communicate potential risks … what pieces or methods could be altered to increase efficiencies, what are they willing to accept), risks … What do you see as potential risks of using different types of synthesis products, or information generated
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-stone-prevention_research-protocol.pdf
    June 15, 2011 - RevMan) version 5.0 software. 33 Random effects models will be used to generate pooled estimates of relativerisks and 95 percent confidence intervals. … The risk of bias—based on study design and conduct—will be rated low, medium, or high. … Prospective study of beverage use and the risk of kidney stones. … History of kidney stones as a possible risk factor for chronic kidney disease.
  5. effectivehealthcare.ahrq.gov/sites/default/files/interactive_media_glasgow_presentation.pdf
    January 01, 2009 -  Knowledge   • ADVISE:   o Provide  specific     o Information  about   o Health  risks
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/worker-safety-wellness-protocol.pdf
    October 26, 2024 - Assessment of Risk of Bias in Individual Studies: We will evaluate each study for risk of bias and methodological … As reported data allow, we will primarily evaluate relative risks (RRs) for dichotomous outcomes, net … Risks Related To Fluoroscopy Radiation Associated With Electrophysiology Procedures. … Blood and body fluid exposure risks among health care workers: results from the Duke Health and Safety … Risk of Bias 2 (RoB 2) tool | Cochrane Methods Available from: https://methods.cochrane.org/risk-bias
  7. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
    February 01, 2012 - Do the effectiveness and risks of FGAs and SGAs vary in differing subpopulations including: • Sex? … The two NRCTs had a high risk of bias. … prospective cohort study; RCS = retrospective cohort study; RCT = randomized controlled trial; RR = relative … first-generation antipsychotic; PCS = prospective cohort study; RCT = randomized controlled trial; RR = relative … Treatment benefits and risks were examined most frequently for schizophrenia; the evidence for conditions
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cesarean-birth-2010_executive.pdf
    January 01, 2010 - reduce fear of labor, education about how to push in labor, and preemptive management of specific risks … of using a partogram to graph labor progress along with active management to augment labor (7.4%, relative … We did not include studies focused only on high-risk populations. … Previous cesarean delivery and risks of placenta previa and placental abruption. … Physician contribution to a cesarean delivery risk model.
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-2.pdf
    April 01, 2022 - mitigation strategies, dose-dependent risks of opioids, and management of opioid use disorder, all … In patients with chronic pain, what are the risks of opioids versus placebo or no opioid on: (1) opioid … In patients with chronic pain, what are the comparative risks of opioids versus nonopioid therapies … In patients with chronic pain, what are the comparative risks of opioids plus nonopioid interventions … Experiencing the Risks of Overutilizing Opioids Among Patients With Non-Tumor Chronic Pain in Ambulant
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_executive.pdf
    August 01, 2016 - It found significant associations between higher plasma DPA and lower risks of all-cause and CVD death … , which included people who may have other nutrition deficiencies that may affect chronic disease risks … or associations of higher n-3 FA intake or biomarker levels and lower cardiovascular disease (CVD) risks … Report of the Joint FAO/WHO Expert Consultation on the Risks and Benefits of Fish Consumption. … Seafood Choices: Balancing Benefits and Risks. Nesheim MC, Yaktine AL, editors.
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatigue-sleepiness-protocol.pdf
    July 01, 2023 - Patient safety risks due to fatigue and sleepiness of healthcare workers were not addressed in MHS … Fatigue Risk Management in the Workplace. … How effective are Fatigue Risk Management Systems (FRMS)? A review. … The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. … ROBINS-I: a tool for assessing risk of bias in non- randomised studies of interventions.
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-257-antenatal-care-evidence-summary.pdf
    June 01, 2022 - overcrowding (of clinics), may increase clinic time available to be directed to patients with high-risk … The RCTs were mostly at low risk of bias, except that studies could not blind the intervention (one … The survey was at low risk of bias. The number of televisits ranged from one to five. … increased risks (e.g., stressors). … The NRCSs were almost all unadjusted and thus subject to high risk of bias.
  13. effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
    January 01, 2015 - strength of evidence that sulfonylurea monotherapy was associated with a 50-percent to 70-percent higher relative … difference; RR = relative risk; SOE = strength of evidence. … Sulfonylurea monotherapy was associated with a 50-percent to 70-percent higher relative risk of cardiovascular … These other monotherapies’ effects on body weight vary, as do their risks, such as congestive heart … medications on weight, hypoglycemia, and gastrointestinal and other side effects; tolerance of unknown risks
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-adults-executive-130408.pdf
    April 01, 2013 - Using Meta-Analyst and STATA® software, we calculated the relative risk and absolute risk difference … We evaluated the strength of the association, defining a priori a large effect when relative risk was … >2 and a very large effect when relative risk was >5.25 We defined low magnitude of the effect when … relative risk was significant but <2. … Our review demonstrated that a relative risk of adverse effects with onabotulinumtoxin A was lower
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-protocol.pdf
    April 17, 2024 - Assessment of Methodological Risk of Bias of Individual Studies: We define the risk of bias as the risk … We will assess the risk of bias for each included study using the Cochrane Risk of Bias 2 (ROB2) tool … category, and risk of bias rating. … >0.8 RR/OR/HR ≥2.0 Abbreviations: HR = hazard ratio; MD = mean difference; OR = odds ratio; RR = relativerisk; SMD = standardized mean difference.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/dental-immunodeficiency-virus-rapid-response.pdf
    May 01, 2025 - risk of bias. … and Human Services similarly recommend modifications for complex cases, such as identified bleeding risks … For example, the Saveetha Dental College guidelines emphasize counseling on oral hygiene, lifestyle risks … continued monitoring for oral lesions and manifestations of HIV, and providing education on lifestyle risks … of bias RR Relative risk SD Standard deviation SME Subject matter expert SR Systematic review
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ped-mindfulness-protocol-amendment.pdf
    February 05, 2025 - Assessment of Methodological Risk of Bias of Individual Studies: We define the risk of bias as the risk … We will assess the risk of bias for each included study using the Cochrane Risk of Bias 2 (ROB2) tool … 100-point scale SMD >0.8 RR/OR ≥2.0 Abbreviations: MD = mean difference; OR = odds ratio; RR = relativerisk; SMD = standardized mean difference. … Strategies; PedsQL = Pediatric Quality of Life Inventory; RADS = Reynolds Adolescent Depression Scale; RR = relative
  18. effectivehealthcare.ahrq.gov/sites/default/files/coronary-artery-disease-testing_disposition-comments.pdf
    March 29, 2016 - Reviewer 2 Methods Analyses was performed in subgroups of patients stratified by different pre-test risks … But only the pre-test risks reported by authors of the studies were used for stratification. … The review team spent substantial time considering ways of standardizing the findings on pre-test risks … is harm in itself if not associated with demonstrable clinical benefit as these entail real, known risks … (unlike radiation in which the risks are theoretical and not known).
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-disposition.pdf
    June 22, 2017 - have added low strength of evidence findings regarding LMWH vs. aspirin in THR patients (similar risks … However, the relative risks of surgical site bleeding are 6.38 (95% CI 4.56-8.92) for LMWH vs ASA, … from LMWHs to FXaIs and found a significant increase in total wound complications (LMWH vs FXaI relative … Therefore, FXaIs have a higher risk of wound complications than LMWH and LMWHs have the highest relative … increase the risk of a VTE event to a level that the risks of surgical site bleeding and death are
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-review-masks-prevention-covid-version-2.pdf
    December 01, 2021 - of infection with SARS-CoV-2, 15 studies on risk of infection with SARS-CoV-1, and one study on risk … in risk of clinical respiratory illness. … Risk factors for SARS infection within hospitals in Hanoi, Vietnam. … incidence of SARS-CoV-2 infection by use of personal protective equipment (PPE) by health workers RelativeRisk factors for SARS infection within hospitals in Hanoi, Vietnam.

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