Results

Total Results: 2,110 records

Showing results for "risks".

261. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
     March 01, 2011 - Based on a single RCT with moderate risk of bias, we found low strength of evidence that the risk of … combination therapy containing rosiglitazone than with a combination of metformin and a sulfonylurea (relative … risk [RR] 2.1). … Hypoglycemia High The risk of mild to moderate hypoglycemia with sulfonylureas exceeds the risk with … low density lipoproteins; mg/dL = milligrams per deciliter; RCT = randomized controlled trial; RR = relative

262. Bladder-Cancer-Non-Muscle-Invasive Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/bladder-cancer-non-muscle-invasive_executive.pdf
     October 01, 2015 - number of available tests and testing strategies, and potential tradeoffs in diagnostic accuracy, risks … We calculated relative risks (RRs) and associated 95% confidence intervals (CIs) based on the information … risk of adverse events (SOE: low) … optimized administration to be associated with lower risk of recurrence and increased risk of local … NMIBC = non–muscle-invasive bladder cancer; NMP22 = nuclear matrix protein 22; OR = odds ratio; RR = relative

263. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/vte-protocol-8-4-10.pdf
     February 01, 2008 - hip replacement [THR], total knee replacement [TKR] or hip fracture surgery [HFS]) carries a high risk … For dichotomous outcomes, weighted averages will be reported as relative risks (RRs) and risk differences … Risk of bias Risk of bias is the degree to which the included studies for any given outcome or comparison … PIOPED Prospective Investigation of Pulmonary Embolism Diagnosis RCT Randomized controlled trial RR Relative … Low molecular weight heparin LMWH Pulmonary embolism PE PIOPED Randomized controlled trial RCT Relative

264. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/blood-clots-hip-knee-surgery_research-protocol.pdf
     February 01, 2008 - hip replacement [THR], total knee replacement [TKR] or hip fracture surgery [HFS]) carries a high risk … For dichotomous outcomes, weighted averages will be reported as relative risks (RRs) and risk differences … Risk of bias Risk of bias is the degree to which the included studies for any given outcome or comparison … PIOPED Prospective Investigation of Pulmonary Embolism Diagnosis RCT Randomized controlled trial RR Relative … Low molecular weight heparin LMWH Pulmonary embolism PE PIOPED Randomized controlled trial RCT Relative

265. Systematic Review on Opioid Treatments for Chronic Pain: Surveillance Report 3 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-3.pdf
     June 01, 2022 - difference: CI = confidence interval; KQ = Key Question; RCT = randomized controlled trial; RR = relative … scale, 95% confidence interval [CI] −0.93 to −0.67, I2=71%), likelihood of a pain response (44 trials, relative … mitigation strategies, dose- dependent risks of opioids, and management of opioid use disorder; for … In patients with chronic pain, what are the comparative risks of opioids versus nonopioid therapies … adverse events; CI = confidence interval; MD = mean difference; RCT = randomized controlled trial; RR = relative

266. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/angina-heart-attack-treatments_research-protocol.pdf
     December 11, 2012 - • In patients with an indication for oral anticoagulant therapy, what are the risks and benefits of … • In patients receiving dual antiplatelet therapy, what are the risks and benefits of adding a PPI? … The duration of treatment and followup will be considered when evaluating the benefits and risks for … Heart failure • Previous stroke • Renal insufficiency • Type of stent • Type of vascular access Bi Risks … review; the duration of treatment and followup will be considered when evaluating the benefits and risks

267. Arthritis-Psoriatric Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
     April 01, 2012 - Similar to RA trials, many questions remain about the risks of these agents across a spectrum of adverse … Finally, very little is known about the benefits or risks of these drugs in different patient subgroups … studies that had a fatal flaw (defined as a methodological shortcoming that leads to a very high risk

268. Zikmund (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/zikmund.pdf
     May 29, 2025 - Am I at high risk or not?” … that is  higher  to this  degree.” • “My risk is  this.” • “My (group’s) risk is  this, … OR “My risk is  this   i I do X, which is higher than my risk i I do Y which is that.” • “My risk … risk for  me than that is.” • “I have bad risk.” • “My risk is  worse.” • Unclear without background … knowledge • “My risk is  worse than their  risk is.” • “My risk is  bad and worse if I do X.

269. Methods-Guide-Chapter-Prioritization-And-Selection-Of-Harms-For-Inclusion-In-Systematic-Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prioritization-selection-of-harms.pdf
     February 01, 2018 - uncommon or rare harms, but be cautious about relying on indirect comparisons to judge comparative risks … , or prevent risks • Need to hold harms as the same rigorous effects as benefits … Surgery related harms: Low risk for complications with laparoscopy (<10%). … Do the comparative risks of treatment harms vary by MDD severity? … Do the benefits and risks of harms of these treatment options differ by subgroups of patients with

270. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1412.pdf
     December 01, 2014 - Body fat distribution is also an important determinant of disease risk. … Surgery carries significant risks of morbidity and mortality, and drug therapy can have undesired side … many patients for treating obesity; however, some of these procedures are very invasive with serious risks … morbidly obese lose 10% of their excess body weight before bariatric surgery to help reduce surgical risks … The panel also voted 6- 2 in favor that the device’s benefits outweighed the risks.34 The manufacturer

271. Kidney-Disease-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_surveillance.pdf
     October 01, 2012 - Relative risk reduction was not significantly different than in similar patients who did not have … commission on Human medicines concluded that the benefits of rosiglitazone no longer outweigh its risks … cohort study of the association of eGFR, proteinuria and adverse clinical outcomes found that the risks … Renal outcomes in hypertensive Black patients at high cardiovascular risk. … Relative risk reduction was not significantly different than in similar patients who did not have

272. Prehospital EMS Blood Transfusion and Fluid Interventions for Hemorrhagic Shock (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-protocol-amendment.pdf
     February 04, 2025 - Assessment of Methodological Risk of Bias of Individual Studies We define the risk of bias as the risk … Studies will be rated as “low risk of bias,” “medium risk of bias,” or “high risk of bias.” … Studies rated “low risk of bias” are considered to have the least risk of bias, and their results are … 100-point scale SMD >0.8 RR/OR ≥2.0 Abbreviations: MD = mean difference; OR = odds ratio; RR = relative … quality improvement; RCT = randomized controlled trial; ROSC = return of spontaneous circulation; RR = relative

273. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-prevention_research-protocol.pdf
     November 03, 2011 - risk). 6. … risk, and absolute risk differences. … We will evaluate the strength of the association, defining a priori a large effect when relative risk … is >2 or <0.5 and a very large effect when relative risk is >5 or <0.2. 47 We will define low magnitude … of the effect when relative risk is significant but <2.

274. Disposition of Comments Report for Comparative Effectiveness of Bariatric Surgery and Nonsurgical Therapy in Adults With Metabolic Conditions and a Body Mass Index of 30.0 to 34.9 kg/m2 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-loss-surgery_disposition-comments.pdf
     June 05, 2013 - Structured Abstract The Review’s Structured Abstract Should Further Highlight the Risks of Bariatric … Risk of metabolic disease, degree of fatness and distribution of fat vary. … The morbidity and mortality risks of obesity have been subject to multiple systematic reviews and from … conditions and a BMI of 30.0 – 34.9 kg/m2, the benefits of bariatric surgery likely outweigh the risks … The morbidity and mortality risks of obesity have been subject to multiple systematic reviews and from

275. Vte-Prophyalaxis Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_executive.pdf
     May 01, 2013 - For studies amenable to pooling quantitatively, we conducted meta- analysis using relative risks by … and several studies had zero events, we used the treatment arm continuity correction to estimate the relative … risks with 95% confidence intervals for the individual studies. … The low rates of such complications, the significant risks of bias in the included studies, and the … Such studies should characterize the relative risks of bleeding and thrombosis across stages of liver

276. Comparative Effectiveness Review No. 234 Evidence Summary: Management of Primary Headaches in Pregnancy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-234-headaches-pregnancy-summary.pdf
     November 01, 2020 - gabapentin, and valproate may have similar adverse effect profiles, but lamotrigine may have a low risk … Lamotrigine may have a lower risk of adverse effects: no increased risk of spontaneous abortion, stillbirth … particular) (low to moderate SoE for specific adverse effects) and antihistamines (moderate SoE) had low risks … no increased risk or unknown risk of other fetal/child AEs, this table includes only the indicator for … increased risk.

277. Association Between Outcomes and Dental Services in People Receiving Treatments That Cause Medication-Related Osteonecrosis of the Jaw: A Rapid Response Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dental-jaw-rapid-response.pdf
     May 01, 2025 - risk of bias. … risk of bias High risk of bias Critically low confidence Critical risk of bias n/a 2.5 Data Synthesis … placed on the importance of coordinated care between dentists and healthcare providers in minimizing risks … However, prior to starting dental treatment, the dentist and patient should discuss the benefits, risks … of bias RR Relative risk SDCEP Scottish Dental Clinical Effectiveness Programme SICMF Italian Society

278. Version 2_Risk of Reinfection From SARS-CoV-2 -- An Update of an Antibody Response Following SARS-CoV-2 Infection and Implications for Immunity: A Living Rapid Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-2-risk-of-reinfection-from-SARSCoV2_0.pdf
     December 31, 2022 - Between March and August 2021, several epidemiological studies have been published comparing infection risks … for various factors), our meta-analysis used absolute counts of events in both groups to obtain a relative … most concerning. 45 A study from Brazil suggested higher reinfection 12 risks … This estimate is formally one minus the relative risk (RR); i.e., protection estimate = 1 – RR. … Risk of Bias Outcome Ascertainment Risk of Bias Outcome Classification Risk of Bias Risk of

279. Osteoporosis-Bone-Fracture Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
     March 01, 2012 - reduction resulting from treatments vary between individuals with different risks for fracture as … with different risks for fracture as determined by bone mineral density, risk assessment score, prior … risk. … How does fracture risk reduction resulting from treatments vary between individuals with different risks … Given the established adverse events associated with treatment, and newly identified risks such as

280. Physiologic Predictors of the Need for Trauma Center Care: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/predictors-trauma-care_research-protocol.pdf
     May 31, 2017 - e.g., odds ratio, relative risk, hazards ratio); (2) discrimination (e.g., area under the receiver operating … of bias,” “medium risk of bias,” or “high risk of bias.” … Adjusted risk estimates may include odds ratios, risk ratios, and hazard ratios. … (e.g., odds ratio, relative risk, hazards ratio); (2) discrimination (e.g., area under the receiver … (e.g., odds ratio, relative risk, hazards ratio); (2) discrimination (e.g., area under the receiver