-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_policymaker.pdf
August 01, 2016 - acamprosate and oral
naltrexone are not suitable or to individuals who prefer
disulfiram and understand its risks … ü» Epidemiological studies consistently related heavy alcohol
consumption to an increased risk of serious … number; SOE = strength of evidence
a This column only includes studies rated as having a low or medium risk … included in the main analysis; these numbers do not include studies rated as having a high
or unclear risk
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-outcomes_methods.pdf
July 01, 2012 - Awareness of these varied
outcomes affects how a decisionmaker balances the benefits and risks of the … consider a broad range of outcomes to illustrate
how these may affect the balance of the benefits and risks … In this
example, the comparison test carries comparable or greater risks. … tests than for screening or
medical tests if the test yields more specific information about mortality risk
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease-appendix-a.pdf
August 31, 2023 - Appendix A - The Effect of Dietary Digestible Carbohydrate Intake on Risk of Cardiovascular Disease
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-risk-assessment-genes_disposition-comments.pdf
July 03, 2012 - Disposition of Comments Report for Multigene Panels in Prostate Cancer Risk Assessment
Source: http … Review Disposition of Comments Report
Research Review Title: Multigene Panels in Prostate Cancer Risk … Multigene Panels in Prostate Cancer Risk Assessment. … and other clinical risk
assessment test.” … The risk significance will certainly
increase once the actual causal variant has been identified.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_appendixes.pdf
March 01, 2009 - Estimating risks and benefits. Cancer 2005;103(6):1147-1153. No
relevant outcomes
52. … Breast cancer risks and prevention: implications of the
Breast Cancer Prevention Trial results. … The estimation and use of absolute risk for weighing the risks and benefits of
selective estrogen receptor … Tamoxifen and breast cancer prevention: are we aware of the
risks? … ‡IBIS: 2-fold relative risk for ages 45 to 70, 4-fold relative risk for ages 40 to 44, 10-fold relative
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effectivehealthcare.ahrq.gov/sites/default/files/cer-236-maternal-fetal-child-outcomes-disposition-comments.pdf
April 15, 2021 - In response, the EPC
added a table to the discussion section on absolute risks of harms when available … presented in the
context of the likelihood that this complication will occur
and the difference in the relative … column whether the
effect is a benefit or a harm and indicate
the magnitude of effect in terms of relative … risks in the results column. … The key information about treatment risks, harms,
and evidence can still be provided without relying
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effectivehealthcare.ahrq.gov/sites/default/files/clinical-pathway-methods-report-appendix-k.pdf
February 01, 2018 - (www.uphs.upenn.edu/cep/methods)
Data synthesis (calculation of relative risks and confidence intervals … exploration of heterogeneity): Qualitative, including descriptive evidence tables with
applicable relative … risks from studies, but not de novo calculations. … GEIH-CDI score may predict risk for recurrent C. … Additional risk factors to identify severe disease and
increased mortality risk include leukopenia (
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/obesity-child_research-protocol.pdf
March 31, 2010 - 5
However, the patterns are complicated, and not all low-income or
minority groups are at high risk … Poor (high risk of bias). … differences or relative risks using a DerSimonian and Laird random
effects model. … differences or relative risks with 95% confidence. … of the degree to which the study population, interventions, outcomes,
and settings are relevant to risks
-
effectivehealthcare.ahrq.gov/sites/default/files/tx-for-localized-prostate-cancer_surveillanceassesment_20120614.pdf
May 01, 2012 - What are the comparative risks, benefits, and outcomes of therapies? … However, the adjusted
relative risk of surgery-related
complications was lower in
patients treated … What are the comparative risks, benefits, and outcomes of therapies? … What are the comparative risks, benefits, and outcomes of therapies? … However, the adjusted
relative risk of surgery-related
complications was lower in patients treated
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tx-for-localized-prostate-cancer_surveillanceassesment_20120614.pdf
May 01, 2012 - What are the comparative risks, benefits, and outcomes of therapies? … However, the adjusted
relative risk of surgery-related
complications was lower in
patients treated … What are the comparative risks, benefits, and outcomes of therapies? … What are the comparative risks, benefits, and outcomes of therapies? … However, the adjusted
relative risk of surgery-related
complications was lower in patients treated
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-evidence-communication_research-protocol.pdf
July 31, 2012 - • Absolute relative risk and relative risk reduction are more understandable than number needed to … treat presentations.18-22
• Absolute relative risk tends to be less persuasive than relative risk reduction … the strength of evidence (also called ambiguity),
uncertainty about the significance of particular risks … severity), uncertainty about
the complexity of information (e.g., the multiplicity or stability of risks … ), and uncertainty resulting from
ignorance about risks.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia_executive.pdf
May 01, 2006 - Hb response rates:
Number of studies reporting 6 15 3
Patients analyzed 2,205 3,293 659
Pooled relative … Transfusion rates:
Number of studies reporting 6 34 4
Patients analyzed 2,158 5,210 950
Pooled relative … Thromboembolic events:
Number of studies reporting 3 30 1
Patients analyzed 1,879 6,092 314
Pooled relative … meaningfully different.
3 Since there was only one trial, this result is a single-study (not pooled) relative … risk.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/aggression_executive.pdf
October 01, 2016 - First is how to best balance the
benefits and risks of seclusion or restraints
with those of various … seclusion and mechanical
restraint.44
CI = confidence interval; N = number; NR = not reported; RR = relative … risk; vs. = versus. … CI = confidence interval; KQ = Key Question; N = number; RR = relative risk; vs. = versus. … confidence interval; CRT= cluster randomized trial; KQ = Key Question; N = number; NR = not reported; RR = relative
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-evidence-communication_executive.pdf
November 01, 2013 - Risk-of-Bias Assessment of Individual Studies
Two reviewers independently rated the risk of bias of … uncertainty are as follows:
• Communicating precision—Studies found mixed
effects of presenting numeric risks … Benefts for me or risks for others: a cross-
culture investigation of the effects of message frames and … Does information
about risks and benefts improve the decision-making
process in cancer screening - … Impact of
information about risks and benefts of cancer screening on
intended participation.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_executive.pdf
June 01, 2013 - Using Meta-Analyst and STATA® software, we calculated
the relative risk and absolute risk difference … We evaluated the strength of the association a
priori, defining a large effect as having relative risk … >2 and
a very large effect as having relative risk >5.21 We defined
low magnitude of effect as having … relative risk that was
significant but <2. … Future studies should also specifically examine the effects
and risks of off-label drug use for migraine
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-appendix-3.xlsx
June 24, 2022 - ’s local data warehouse and research portfolio, which may include legal counsel to manage liability risk … NAM2019 What special vulnerabilities or risks are anticipated in the study population? … NAM2019 The risk/benefit ratio of trial participation? … Generally, an intervention is not reasonable and necessary if its risks outweigh its benefits. … Generally, an intervention is not reasonable and necessary if its risks outweigh its benefits.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-214-afib-disposition-comments.pdf
October 30, 2019 - As mentioned above, I believe there
is a gap in research on the relative risks and
benefits of anticoagulation … clear
that the key quantities needed for rational
treatment choice are the differences in absolute
risks … of risk. … Results Would be helpful to report absolute rates of major
CVA and major bleeds to help interpret the relative … Given the amount of evidence
we have focused our report on
the relative risk estimates.
129.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-afib-update_research-protocol-amended.pdf
October 27, 2017 - Treatment Description
to better understand the relative … risks and benefits of these drugs
based on individual patient characteristics. … A population-based study of the long-term risks associated
with atrial fibrillation: 20-year follow-up … "[Mesh] OR risk[tiab] OR risks[tiab] OR "Predictive Value of Tests"[Mesh] OR predict[tiab]
OR predicts … "[Mesh] OR risk[tiab] OR risks[tiab] OR "Safety"[Mesh] OR safety[tiab] OR safe[tiab] OR
"Incidence"[
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/radiation-therapy-brain-metases-protocol.pdf
October 10, 2019 - risks
(RRs), and hazard ratios (HRs). … risks. … Deaths due to brain metastases (number of patients, relative risk)
5. … Key results that are based on measure-independent effect estimates, such as relative risks
or standardized … of bias
RR relative risk
SD standard deviation
SMD standardized mean difference
SRS stereotactic
-
effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-summary.pdf
April 01, 2020 - Harms and adverse events:
– What are the risks of nonopioid
pharmacologic agents for harms including … points on a 0 to 100-point scale
• SMD >0.8
• RR/OR ≥2.0
MD = mean difference; OR = odds ratio; RR = relative … response with SNRI antidepressants
(odds ratio [OR] 1.61 to 2.33) while we found a
moderate effect (relative … ).15 Differences in magnitude could be due to
the addition of 15 studies in our report, reporting
relative … risks rather than odds ratios, and using
direct comparisons rather than network analysis.