-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
November 01, 2012 - risks.35 When
present, statistical heterogeneity was explored through
subgroup and sensitivity analyses … Relative risk
estimates ranged from 1.01 to 1.33 in the four trials and may
have varied in part due … Relative risk estimates ranged from 0.89 to 1.2.
Moderate
11
Table A. … risk estimates for SVR in men vs. women, and no clear
difference in relative risk estimates for Black … for risk of harms that were
similar to the risk estimates based on all trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_clinician.pdf
May 01, 2011 - .
�� The evidence about benefits and
risks of the various pain-control
interventions that may be used
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dental-post-transplant-complications-rapid-research.pdf
May 01, 2025 - risk of bias. … This Report AMSTAR2 Rating ROBINS Rating RoB2 Rating
Good High confidence Low risk of bias Low risk … risk of bias High risk of bias
Critically low confidence Critical risk of bias n/a
2.5 Data Synthesis … Transplantation (COMMIT)
Group
Practical Recommendations for
Long-term Management of
Modifiable Risks … Risk of Bias Assessments
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-executive-summary.pdf
October 01, 2022 - Summary
Main Points
Background and Purpose
Infantile epilepsies have serious short-term health risks
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_executive.pdf
February 01, 2014 - ,
and placenta previa.7-10 Health risks to the
fetus include low birth weight, restricted
growth, … Administration places the transdermal nicotine patch in
pregnancy category D, which indicates there are known
risks … to the fetus, but potential benefits may outweigh risks
in some cases. … adverse
fetal effects and no adequate human studies are available,
but potential benefits may outweigh risks … Prenatal smoking and
risk of intrapartum stillbirth.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-therapy-management-1_research.pdf
July 01, 2012 - in High Risk Medicare Beneficiaries Toolkit
Daniel R. … Improving Medication Safety in High Risk Medicare
Beneficiaries Toolkit. … reviews pharmacodynamic and pharmacokinetic changes that are
common in elderly adult, explains the risks … • The patient is at risk for a potential ADE. … The patient is at risk for a potential
ADE.
a.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
January 01, 2007 - Many questions remain
about the risks of these agents across a spectrum of
adverse events from relatively … Finally, very little is known about
the benefits or risks of these drugs in different patient
subgroups … All the
same issues noted for RA of short- and long-term risks
and safety, as well as performance in … withdrawals attributed to adverse events were not
significantly different for leflunomide vs. methotrexate
(relative … risk [RR], 1.19; 95-percent CI, 0.89-1.6) or
sulfasalazine (RR, 0.77; 95-percent CI, 0.45-1.33).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-risk-of-bias.pdf
December 01, 2017 - Assessing the Risk of Bias in Systematic Reviews of Health Care Interventions
Assessing the Risk of … Defining Risk of Bias
• Risk of bias is:
► An assessment of the internal validity of the individual … Risk of Bias
There are five stages in assessing risk of bias. … Develop Protocol
Pilot test and train
Perform Assessment of Risk of Bias of Individual Studies
Use Risk … Use risk-of-bias assessment tools that can identify potential risk-of-bias categories specific to the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_executive.pdf
March 01, 2013 - irregular bleeding.81
COCs
Primary care providers and many women are aware of the
most serious risks … included over 38,000 person-
years of contraceptive vaginal ring use reported an
elevated adjusted relative … These agents include a boxed
warning on the product labels about cardiovascular and
GI risks.104-106 … found in
the Food and Drug Administration sources discussed
in the main document and do not have risks … Thrombotic risks of oral contraceptives. Curr Opin
Obstet Gynecol 2012 Aug;24(4):235-40.
-
effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1512.pdf
December 01, 2015 - is an example of an initiative aimed at improving surgical outcomes by assessing
patient-specific risks … Key Expert Comments: Programs such as MSHOP may address an unmet need for
reducing surgical risks … that clinicians would be likely to adopt a MSHOP-like
program based on the potential to decrease risks … Unmet need and health outcomes: An unmet need exists to decrease surgical risks and
complications, … biggest hurdle, which is patient compliance.68
Acceptance and adoption: The potential to decrease risks
-
effectivehealthcare.ahrq.gov/sites/default/files/s89.pdf
October 01, 2007 - †One-sided test; when relative risk �1, the log likelihood ratio was set to 0. … Cases
in the 42 d After
Meningococcal
Vaccination by Week 106
Relative Risk in
Vaccinated Group
Log … †One-sided test; when relative risk �1, the log likelihood ratio was set to 0. … The dashed line depicts
the relative risk.
TABLE 4. … Cases of
Thrombocytopenia
in the 42 d After
Vaccination
Relative Risk Log Likelihood Ratio*Observed
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-206-evidence-summary-sodium-potassium.pdf
June 01, 2018 - Effectiveness Review
Number 206
Sodium and Potassium Intake: Effects on
Chronic Disease Outcomes and Risks … CVD, stroke,
congestive heart failure, and kidney disease.16 Lowering
blood pressure lowers these risks … through 2002) and updated
evidence, regarding sodium and potassium intakes, blood
pressure, and the risks … Quality (Risk of Bias) Assessment of Individual
Studies
Risk of bias (RoB) of eligible studies was … Sodium and Potassium
Intake: Effects on Chronic Disease Outcomes and Risks.
-
effectivehealthcare.ahrq.gov/sites/default/files/s158.pdf
October 01, 2007 - Generaliza-
tion from trials can be erroneous because effect sizes, base-
line risks, and comorbidity … Without adjustment for smoking, the relative risk of lung
cancer in those exposed to diesel exhaust was … This multiple im-
putation led to an estimate of the relative risk for lung cancer
and exposure to diesel … Because the relative risk
for vasectomy and myocardial infarction was essentially the
same before and … Correction of logistic regression
relative risk estimates and confidence intervals for measurement error
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause-protocol-130612.pdf
June 12, 2013 - While hormone therapy is an effective treatment for menopausal symptoms, concerns about
potential risks … , and increasing the risk of thromboembolism
and gallbladder disease. … When there is suggestion or suspicion of effects
dependent on baseline risks, potential effects will … Duration of menopausal hot flushes and associated
risk factors. … Benefits and risks of postmenopausal hormone
therapy when it is initiated soon after menopause.
-
effectivehealthcare.ahrq.gov/sites/default/files/considerations-for-statistical-chapter-10.pptx
January 01, 2013 - fixed followup and is rare, Poisson regression with robust standard errors can be used to estimate relative … risks and get correct confidence intervals. … UW Biostatistics Working Paper Series: Relative risk regression in medical research: models, contrasts … Disease Risk Scores
Disease Risk Scores
The disease risk score (DRS) is an alternative approach to … The DRS is useful for summarizing disease risk and assessing effect modification by disease risk.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label_executive.pdf
January 01, 2007 - Relative risk of “responding” was 2.74 (95-percent
3
CI: 1.50 to 5.01) for augmentation with quetiapine … The difference in risk for death was small but
statistically significant. … Sensitivity analyses did
not show evidence for differential risks for
individual atypical antipsychotics … make this statement
based on the prevalence of the condition and
uncertainty about the balance between risks … Information is needed on
how the risk compares to risks for other treatments.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-future_research.pdf
February 01, 2012 - 4 Do the efficacy and risks of FGAs and SGAs vary in differing subpopulations including sex, age group … SGAs (Appendix A, Table A-2) are generally
thought to have a lower risk of EPS.2,3 The risk of NMS is … Do the efficacy and risks of FGAs and SGAs vary in differing subpopulations
including
• Sex? … Studies shed light on risks and
trends in pediatric antipsychotic prescribing. … comparators, outcomes, time frames, and settings
RCTs randomized controlled trials
RN research need
RR relative
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_surveillance.pdf
December 01, 2015 - Relative risk estimates: 0.89 to 1.2. … Women: No difference in relative risk estimates for SVR
•! Blacks vs. … Non-Black patients: No clear difference in relative risk estimates. … Relative risk estimates: 0.89 to
1.2. … Non-Black patients: No
clear difference in relative risk
estimates.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_surveillance.pdf
December 01, 2015 - Relative risk estimates: 0.89 to 1.2. … Women: No difference in relative risk estimates for SVR
•! Blacks vs. … Non-Black patients: No clear difference in relative risk estimates. … Relative risk estimates: 0.89 to
1.2. … Non-Black patients: No
clear difference in relative risk
estimates.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth-disposition-121205.pdf
September 07, 2012 - Combs paper and the
general need for larger datasets to assess
harms such as IUFD and neonatal death risks … Results Page 53 of 518, the statement is made that “the meta-estimate
combining these three trials is a relative … risk of 0.44 (95 percent
CI: 0.26, 0.76)”. … I think the data indicating
differential efficacy with different risks for preterm birth is
sufficient … to allow the authors to make the statement that in
future analyses, different risks would need to be