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Showing results for "risks".

121. Disposition of Comments: Comparative Effectiveness Review No. 238 Cervical Ripening in the Outpatient Setting (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-outpatient-setting-comments.pdf
     March 22, 2021 - We support the review’s examination of the relative risks and outcomes of outpatient interventions … these findings to the population of childbearing women in the United States will likely increase risk … Like harms and risks, these factors can impact patients' decision-making regarding inpatient versus

122. S108 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s108.pdf
     October 01, 2007 - bined into the discharge state in the simulations presented here to avoid problems related to competing risks … Adverse event risks were calibrated such that approx- imately 30% of synthetic individuals experienced … is less than 10%.40,41 In this simulation, the interval-specific risks were less than 10%. … The reason for this difference was that individuals who remained in the hospital had longer period of risks … framework of inverse probabil- ity of censoring makes it possible to address censoring and competing risks

123. CER 244 Evidence Summary: Safety of Vaccines Used for Routine Immunization in the United States: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-244-safety-vaccines-update-evidence-summary.pdf
     May 01, 2021 - There continues to be no evidence of increased risk of adverse events for vaccines currently recommended … We documented the observed rates of adverse events and assessed the relative risks between vaccinated … some observational studies showed increased risk) Moderate: No evidence of increased risk of asthma … or to definitively exclude a risk of such adverse events. … Potential risks of rare adverse events should be weighed against the protective benefits that vaccines

124. Disposition of Comments for CER 147 Menopausal Symptoms: Comparative Effectiveness of Therapies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_disposition-comments.pdf
     March 05, 2015 - We have added to applicability sections in KQ2 potential differences in relative risk in gallbladder … It is our view that issues concerning age and risks are adequately highlighted. … In the Million Women Study the relative risk was lower with transdermal administration, but not eliminated … and the risk-benefit profile of estrogen therapy. … increase the risk of endometrial cancer.’

125. Evidence Summary: Comparative Effectiveness Review No. 238: Cervical Ripening (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-evidence-summary.pdf
     March 01, 2021 - Primary birth outcome: cesarean delivery Key Question Intervention Findingsa Studies Incidence Relative … vs. 40% RR 0.98 (0.80 to 1.22) CI = confidence interval; RCT = randomized controlled trial; RR = relative … Primary fetal harms outcomes Key Question Intervention Outcome Findingsa Studies Incidence Relative … difference; RR = relative risk a Difference of <1% = little or no difference; >1% to 3% = small difference … Primary maternal harms outcomes Key Question Intervention Outcome Findingsa Studies Incidence Relative

126. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1506.pdf
     June 01, 2015 - potential risks with liraglutide use. … The relative risks for minor complications, for example gastric ulcers and erosions were significantly … . <0.1 events per 100 patient-years at risk). … evaluation and mitigation strategy (REMS) for approval to inform prescribers of potential risks from … Studies better defining the potential long-term risks (breast cancer and cardiovascular risks) need

127. Disposition of Comments Report for Whole-Body Vibration Therapy for Osteoporosis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-vibration-therapy_disposition-comments.pdf
     November 15, 2011 - These people are also at risk for low bone density or osteoporosis, due to related risk factors such … There are standardized methods to assess the risk of bias, e.g., JADAD, PEDro. … Commentator & Affiliation Section Comment Response Peer Reviewer #2 Findings p. 6 l. 3-9 This section on risks … We have provided additional information about these risks. … distinctive and adjunctive therapy and the importance of exploring subgroups of patients with differing risks

128. Evaluation of Mental Health Applications (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-health-app-protocol-updated.pdf
     January 01, 2018 - The framework will take into account current FDA status on the use and classification of risks of apps … and elements of potential framework, including conditions for which mental health apps are helpful, risks … one key decisional criterion would be about leveraging existing 4 frameworks for evidence and risk … such as data usage and sharing of data on social media as well as regulatory oversight; safety and risk … Assessment of risks posed due to the use of the app will be a critical element of the framework and

129. Acs-Pci-Adjunctive-Devices Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-pci-adjunctive-devices_research-protocol.pdf
     July 01, 2010 - For dichotomous outcomes, weighted averages will be reported as relative risks and risk differences … expected, a DerSimonian and Laird random-effects model will be used when pooling data and calculating relative … risks, risk differences, and 95 percent confidence intervals.9 When pooling continuous outcomes, weighted … This system uses four required domains—risk of bias, consistency, directness, and precision. … Risk of Bias Risk of bias is the degree to which the included studies for any given outcome or comparison

130. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pain-chronic_disposition-comments.pdf
     September 01, 2011 - accumulating translational research points to genotypic factors that place patients at increased risk … The comment on MPP risks is intended to specifically apply to risks due to the combination of treatments—that … is, beyond the risks from each of the individual treatment components. … affected by inappropriate prescribing of analgesia of particular concern is the potential to increase risk … Peer Reviewer #5 Next Steps Other next steps that should be commented upon include risk stratification

131. Knowledge Brief #1 Public Deliberation on Health Topics (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/deliberative-methods_research.pdf
     February 01, 2013 - Learning more about the public’s values concerning the risks and benefits of a health care intervention … , or concerning the distribution of risks and benefits across the population can inform guidelines regarding

132. #06 Developmental Delays ADHD, and Autism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/06_devdelays_autism_potential_high_impact_june_2012.pdf
     January 01, 2012 - Significant clinical opposition to its use exists because of its potential risks to children and a … They also subject patients to risks of adverse events, some of which could be serious.

133. Assessing the Risk of Bias of Individual Studies in Systematic Reviews of Health Care Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias-individual-studies_methods.pdf
     March 01, 2012 - presenting data on individual endpoints;33 2. selective outcome reporting—for example, reporting relative … Other study designs have specific and inherent risks of biases that cannot be minimized. … observational studies into the review and (2) when evaluating individual studies for design-specific risks … In assessing the risk of bias of studies, EPCs should specify constructs and risks of bias specific … The final domain, “other sources of bias,” includes design specific risks of bias, baseline imbalance

134. Executive Summary: ADHD Diagnosis and Treatment in Children and Adolescents (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-267-adhd-executive-summary.pdf
     March 01, 2024 - • We found too few studies reporting on diversion to quantify the risk of diversion of pharmacological … We converted to scale-independent standardized mean differences (SMD) and relative risks (RR) together … The risk of bias in included studies varied considerably. … We found too few studies reporting on diversion to quantify the risk of diversion of pharmacological … Medication therapy remains a central treatment modality, though with a risk of side effects, even as

135. Executive Summary: Systematic Review_Implementing Recommended Mental Health and Substance Use Screening and Counseling Interventions in Primary Care Settings for Children and Adolescents (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/screening-counseling-interventions-executive-summary.pdf
     April 01, 2025 - Incorporating behavioral health into primary care settings enhanced screening for general behavioral health risks … the clinician support with reminders arm delivered brief advice and provided information on health risks … for clinicians with computer-based reminders likely improves delivery of information about health risks … Youth Risk Behavior Survey: data summary & trends report. … Improving adolescent health risk assessment: a multi-method pilot study.

136. Cervical Ripening in the Outpatient Setting (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ocr-protocol-final_1.pdf
     December 18, 2019 - more satisfying IOL, while reducing inpatient length of stay compared to inpatient CR. 2 The risks … However, there are concerns regarding potential risks of outpatient CR to the woman and fetus in comparison … The risks of CR may be mitigated through the choice of CR method and clinical management. … Careful review of existing literature is needed to elucidate whether these risks occur more frequently … versus inpatient setting and whether maternal or fetal characteristics differentially affect these risks

137. Revised Protocol - Opioids 12 13 13[1] (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-pain-opioid-treatment_research-protocol.pdf
     December 19, 2013 - Evidence-based Practice Center Systematic Review Protocol Project Title: The Effectiveness and Risks … In patients with chronic pain, what are the risks of opioids versus placebo or no opioid on: 1) opioid … for initiating and titrating opioids for outcomes related to pain, function, and quality of life; risks … Risk assessment and risk mitigation strategies Source: www.effectivehealthcare.ahrq.gov Published … Analytic Framework for the Effectiveness and Risks of Long-term Opioid Treatment of Chronic Pain IV

138. Disposition of comments_Comparative Effectiveness Review No. 244: Safety of Vaccines Used for Routine Immunization in the United States: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-244-safety-of-vaccines.pdf
     May 25, 2021 - The issue is relative risk. … The relative risk across all 19 RCTs for which we could combine data was 0.65 (95% CI 0.41, 1.05). … For consistency reasons, we have calculated the relative risk throughout; in order to calculate the … For consistency reasons, we have calculated the relative risk throughout; in order to calculate the … risk to the vaccine exposure is not presented in the abstract or how the relative risk was determined

139. Major-Depressive-Disorder Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/major-depressive-disorder_executive.pdf
     December 01, 2015 - In adult patients with MDD, what are the comparative risks of harms of these treatment options— 1. … Do the comparative risks of treatment harms vary by MDD severity? • KQ 4. … Do the benefits and risks of harms of these treatment options differ by subgroups of patients with … Comparative Benefits and Risks of Harms for Selected Subgroups No trials were specifically designed … availability) following a discussion of the advantages and disadvantages of each treatment option, including risks

140. Kidney-Disease-Medicine Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_executive.pdf
     January 01, 2012 - risks and 95 percent confidence intervals. … Relative risk reduction was not significantly different than in similar patients who did not have microalbuminuria … • Inconsistent data suggested greater relative risk reduction for several clinical vascular outcomes … Inconsistent results suggested possibly a greater relative risk reduction with beta blockers in patients … • No RCT data address whether treatments have different relative risk reduction in clinical outcomes