-
effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-229-opioid-treatments-chronic-pain-evidence-summary.pdf
April 01, 2020 - nonopioids alone, and opioids
plus nonopioids versus opioids alone at short-term
followup.16 Pooled relative … of overdose; risks
were higher at increased gabapentinoid doses (SOE: low). … of overdose;
risks were higher at increased gabapentinoid doses (SOE: low). … and risks related to opioid use
disorder, was lacking. … Annual Surveillance Report of Drug-Related Risks and
Outcomes--United States, 2017.
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effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/thrombosis-plays-a-a-key-role-in-the-pathophysiology-of-myocardial-infarction-a-leading-cause-of-morbidity-and-mortality-there-have-been-a-number-of-devices-proposed-for-mechanical-thrombectomy-in-patients-with-in-the-settin
November 01, 2017 - Identification of a disease or condition:
Screening or diagnosis/identification for a particular disease, or risk … assessment for a disease
Risks or harms that can come from a disease identification tool or test … Harms: Are there risks, side effects, or harms you are concerned about? … what those are:
In addition to the inherent risks … associated with cardiac catherization, are there increased risk of bleeding vessel rupure, distal embolization
-
effectivehealthcare-admin.ahrq.gov/health-topics/opioid-abuse-and-addiction
April 01, 2021 - They cannot be awakened or are unable to speak
Their breathing or heartbeat slows or stops
Other risks … The risks of dependence and addiction are higher if you abuse the medicines .
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-2.pdf
February 01, 2018 - individual trials considered in
meta-analyses
- More likely to be consistent
even with differing baseline
risks … interpretable than OR
Odds Ratio
(OR)
- More likely to be consistent
even with differing baseline
risks … considered in
meta-analyses
- Not easily interpretable
- Can be misleading when interpreted like
relative … risks
- Widespread use in meta-analyses may
be because of convenience and history
rather than an assessment … differ in baseline risk
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0064_11-23-2008.pdf
January 01, 2008 - 1 individual
Nomination
Summary:
The anonymous nominator is interested in the comparative risks … What are the health risks and benefits of trabeculectomy as compared to
alternatives, including laser … Does age modify this risk?
From Nominator 2 (individual):
1.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/mccullough.pdf
January 01, 2011 - and inadequate risk assessment in
reaching judgments
about medical reasonableness, the physician … should assume that these risks are
clinically significant. … disapproval,
discourage, but do not abandon
the patient
When evidence level
for judgment of
risk … the benefit
of doing so
Relieved of the burden of decision making
o Informed about
the risk … engage in
scientifically sophisticated moral management
of medical uncertainty
o First-‐trimester risk
-
effectivehealthcare-admin.ahrq.gov/products/methods-guidance-harms/methods
May 01, 2020 - However, placebo-controlled RCTs may also provide important information on absolute and relative risks … trials. 35 There was no clear tendency for randomized trials or observational studies to report larger relative … risks. … three outcomes were more than 0.20. 76 However, the 95-percent confidence intervals for estimates of relative … risks for these three adverse events encompassed clinically significant increases in risk (-13.5 percent
-
effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/with-the-rates-of-birth-by-cesarean-section-on-the-rise-what-factors-influence-and-which-have-the-greatest-impact-on-the-probability-of-delivery-by-cesarean-in-low-risk-women-which-interventions-are-most-effective-at-reducin
November 01, 2017 - Which interventions are most effective at reducing the risk… … The patient population of most interest is low-risk, pregnant women. … Describe any health-related risks, side effects, or harms that you are concerned about. … For infants potential risks include respiratory issues, and the development of asthma. … The research should include the health risks of not delivering by cesarean when medically necessary.
-
effectivehealthcare-admin.ahrq.gov/products/renal-cancer/research
December 01, 2019 - Investigators abstracted data sequentially and assessed risk of bias independently. … Percutaneous renal mass sampling with core biopsy is a low risk and sensitive procedure, but is associated … across all management strategies, with differences in overall survival that are explained by competing risks … strategy based on similar cancer-specific survival but different overall survival (competing health risks … Diagnostic accuracy and risks of biopsy in the diagnosis of a renal mass suspicious for localized renal
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/technical-brief-34-health-worker-certification-summary.pdf
March 01, 2020 - • To assess the current state of the evidence about the processes, risks, benefits, and implications … set
and knowledge base, and increase sustainable funding for services.6-11 However, some
important risks … promote CHWs' integration into healthcare settings and
provided context about certification processes, risks
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/monitoring-programs-protocol.pdf
January 01, 2024 - Coordinator role, along with a number of
policies to prevent drug shortages and mitigate supply chain risks … reported supply chain shortages in
2021,8 and supply chain shortages were second among the top 10 risks … Supply chain shortages ranked
second among Top 10 risks facing healthcare
organizations [internet]. … Meeting (PA):
ECRI; 2022. https://blog.ecri.org/supply-chain-
shortages-ranked-second-among-top-10-risks … https://blog.ecri.org/supply-chain-shortages-ranked-second-among-top-10-risks-facing-healthcare-organizations
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_consumer.pdf
May 01, 2011 - People with broken hips may be at risk for other
problems, such as pneumonia, blood clots, and muscle … There is very little known about
the benefits and risks of traction, acupressure, muscle-relaxation … We do not know if using both traction and medicines for pain increases
your risks of serious side effects … What are the risks of acupressure, muscle-relaxation
therapy, and TENS? … There is not enough research to
say if these options have
any risks or can cause
any side effects
-
effectivehealthcare-admin.ahrq.gov/products/effect-protein-intake/research
March 01, 2025 - on the association between dietary protein intake and bone disease, kidney disease, and sarcopenia risks … To assess chronic disease risk, studies used intermediate markers, including surrogate markers for bone … We assessed the risk of bias, performed a qualitative synthesis of studies rated as low to moderate risk … Thirteen of these, rated as low to moderate risk of bias, were included in our synthesis. … The evidence gathered since 2000 on associations between dietary protein intake and the risks of bone
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
November 01, 2008 - However,
placebo-controlled RCTs may also provide important information on absolute and relative risks … 35
There was no clear tendency for randomized trials or
observational studies to report larger relative … risks. … outcomes were more than 0.20.
76
However, the 95-percent confidence intervals for
estimates of relative … risks for these three adverse events encompassed clinically significant
increases in risk (-13.5 percent
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
November 01, 2008 - However,
placebo-controlled RCTs may also provide important information on absolute and relative risks … 35
There was no clear tendency for randomized trials or
observational studies to report larger relative … risks. … outcomes were more than 0.20.
76
However, the 95-percent confidence intervals for
estimates of relative … risks for these three adverse events encompassed clinically significant
increases in risk (-13.5 percent
-
effectivehealthcare-admin.ahrq.gov/products/appropriate-opioid-tapers/research
April 01, 2021 - whom an individualized assessment determines that benefits of long-term opioid therapy do not outweigh risks … to support opioid tapering in patients with chronic pain, effectiveness of interventions to mitigate risks … Observational studies found that opioid discontinuation might be associated with increased risk of overdose … indication for discontinuing opioids, the tapering strategy used, or use of strategies for mitigating risk
-
effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/should-subclinical-hypothroidism-be-treated
November 01, 2017 - Identification of a disease or condition:
Screening or diagnosis/identification for a particular disease, or risk … assessment for a disease
Risks or harms that can come from a disease identification tool or test … Management of a condition or particular system of care
Delivery of a health service
Referral
Risks … Harms: Are there risks, side effects, or harms you are concerned about?
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
October 01, 2011 - and nonselective) appear to be
associated with increased risk of serious CV risks. … clear
association between longer duration of therapy with
COX-2 selective NSAIDs and increase in the relative … However, because the event rates increases in older
patients, even if the relative risk estimates are … There was
insufficient evidence to evaluate comparative risks of
GI bleeding or CV events. … anti-inflammatory drug; OR = odds ratio; PPI = proton pump inhibitor;
PUD = peptic ulcer disease; RR = relative
-
effectivehealthcare-admin.ahrq.gov/products/hip-fracture-pain/consumer
November 01, 2020 - People with broken hips may be at risk for other problems, such as pneumonia, blood clots, and muscle … There is very little known about the benefits and risks of traction, acupressure, muscle-relaxation therapy … We do not know if using both traction and medicines for pain increases your risks of serious side effects … What are the risks of acupressure, muscle-relaxation therapy, and TENS? … There is not enough research to say if these options have any risks or can cause any side effects for
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0411_02-10-2011.pdf
January 01, 2011 - In addition, they question whether the benefits and harms of these
tests vary by the risk of the surgical … procedure, the clinical condition, or comorbidities
and risks of particular patients. … Do the benefits or harms of routine preoperative tests vary by the risk of the
surgical procedure (low … vs. medium vs. high risk)? … benefits or harms of
routine preoperative tests vary by the clinical conditions, comorbidities, or risks