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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary53/vitamin-supplementation-to-prevent-cancer-and-cvd-counseling-and-preventive-medication-2003
July 01, 2003 - early for a significant adverse effect of beta-carotene on lung cancer incidence among heavy smokers (relative … A U.S. trial 11 found no effect on the relative risk for recurrence in subjects randomized to beta-carotene … above) and vitamin C plus vitamin E. 11 After 4 years on study (3 years between colonoscopies), the relative … Leisure World Study) are now reaching a stage of maturity in which they can provide information on risks … Beta-carotene supplementation for patients with low baseline levels and decreased risks of total and
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/nnkwqkX-Nk6v3gsphVATUD
September 01, 2002 - Predicting Risk for Osteoporosis or
Fracture
The USPSTF evaluated both individual risk
factors and … than in women at
lower risk. … Over 3 years of treatment in
high-risk women, alendronate reduced the risk for
hip fracture (1.1% vs. … replacement therapy include venous
thromboembolic events, endometrial cancer, and
cholecystitis, all with relative … risks of approximately
2.0.12 Both raloxifene and tamoxifen are associated
with thromboembolic events
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/lung-cancer-screening-december-2013
December 31, 2013 - Future improvements in risk assessment tools will help clinicians better individualize patients' risks … The relative risk for all-cause mortality in the DLCST was 1.46 (95% CI, 0.99 to 2.15). … When these 3 fair- or good-quality trials were combined in a meta-analysis, the relative risk for lung … effect of enabling persons to continue smoking with the perception that medical care can mitigate the risks … exposure, family history, and history of other lung diseases are important when assessing patients' risks
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/efwy72cuMdhcF2jotkhTzC
March 29, 2019 - of AIDS-related events
(4.5% vs 7.0%; relative risk [RR], 0.65 [95% CI, 0.44-0.95]). … initiation of ART within 6 months of
CD4 cell counts decreasing to less than 500/mL3, there were
greater risks … 95% CI, 0.02-0.22]),34 and 3 observational studies (Partners of
People on ART—A New Evaluation of the Risks … of HIV infection are small, and the clinical ben-
efits of ART substantially outweigh the potential risks … Benefits and
risks of antiretroviral therapy for perinatal HIV
prevention.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/WN7F3WW6RQFDkHay87a3Dx
November 18, 2020 - lung cancer is smoking.2,3 Smok-
ingisestimatedtoaccountforabout90%ofall lungcancercases,2 with
a relative … a risk factor for lung cancer. … Overdiagnosis of lung cancer and the risks of
radiation exposure are harms, although their exact magnitude … median pack-year smoking history in NELSON trial participants was
38 pack-years.11
The NLST reported a relative … data with additional follow-up and end point verification
reported a relative risk reduction of 16%
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/NaBk7mpgSEmpoBKmK5Qvzn
November 18, 2020 - L ung cancer is the second most common cancer and the lead- a relative risk of lung cancer approximately … Assessment of Risk
Smoking and older age are the 2 most important risk factors for
lung cancer.3-5 … Overdiagnosis of lung cancer and the risks of
radiation exposure are harms, although their exact magnitude … pack-year smoking history in NELSON trial participants was
38 pack-years.11
The NLST reported a relative … data with additional follow-up and end point verification
reported a relative risk reduction of 16%
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/menopausal-hormone-therapy-preventive-medication
November 01, 2022 - disease events in persons treated with estrogen plus progestin compared with placebo (2.8% vs 2.6%; relative … risk [RR], 1.12 [95% CI, 0.94-1.33]) during a mean follow-up of 4 years. … if alternative therapies are not tolerated, based on a careful assessment of individual benefits and risks … Estrogen plus progestin and risk of venous thrombosis. JAMA . 2004;292(13):1573-1580. 27. … Benefits and risks of postmenopausal hormone therapy when it is initiated soon after menopause.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/V7SNHdqvUyT7e2hQt5HbFp
December 12, 2017 - Absent meta-analytic esti-
mates, relative risks of outcomes of interest were based primarily
on a recent … WHIMS did not find an elevated risk of mild cog-
nitive impairment.72
Based on the WHI data, risks for … Point estimate is slightly different from estimate reported in Manson et al15
because of the use of relative … risks instead of hazard ratios. … Relative risks (RRs) were calculated to
determine absolute risk reductions and increases presented in
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/lung-cancer-screening
March 09, 2021 - is smoking. 2 , 3 Smoking is estimated to account for about 90% of all lung cancer cases, 2 with a relative … Assessment of Risk
Smoking and older age are the 2 most important risk factors for lung cancer. 3-5 … Overdiagnosis of lung cancer and the risks of radiation exposure are harms, although their exact magnitude … pack-year smoking history in NELSON trial participants was 38 pack-years. 11
The NLST reported a relative … data with additional follow-up and end point verification reported a relative risk reduction of 16% (
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www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/hypertensive-disorders-pregnancy-screening
February 07, 2023 - factor. 33 Clinicians should also be aware of the risks of poor health outcomes for populations at … risk. … health systems, and clinical practices) to address underlying health inequities that increase health risks … -1.58 days [95% CI, -8.10 to 4.94 days]); number of hypertensive disorders of pregnancy diagnoses (relative … Hispanic (75%), White (19%), Black (9%), or “other” (6%) and the study was conducted in a setting with risks
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www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/hiv-prep-prevention-discussion-guide.pdf
August 22, 2023 - If you’re at increased risk of getting HIV, PrEP can help prevent HIV. … 6 How else can I reduce my risk of getting HIV and
other STIs?
The U.S. … of HIV acquisition to decrease the risk
of acquiring HIV. … (USPSTF Grade: A)
Determining Risk of HIV
The USPSTF defines increased risk for HIV as follows:
1 Sexually … by pregnant people if the healthcare professional and patient decide that
the benefits outweigh the risks
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/mk-eb9VtB_jx885wnjuzk3
January 01, 2024 - For composite cardiovascular outcomes, relative risk estimates
were very similar for men and women in … Although relative risk estimates across subgroups were simi-
lar, absolute benefits were greater in subgroups … similar relative risk esti-
mates, the absolute benefits of statin therapy will be greater in
populations … Statins: is it really time to reassess
benefits and risks? … Risks
associated with statin therapy: a systematic
overview of randomized clinical trials.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/pACFPdCoN8fVoddBs-_CLE
November 12, 2019 - Tamoxifen reduced invasive breast cancer more than
raloxifene in the head-to-head trial (relative risk … Risks for breast, ovarian, and other types of BRCA-
related cancer are greatly increased in patients … Average
risks of breast and ovarian cancer associated with
BRCA1 or BRCA2 mutations detected in case … Cancer risks for BRCA1 and BRCA2 mutation
carriers: results from prospective analysis of
EMBRACE. … Familial breast cancer:
classification, care and managing breast cancer and
related risks in people with
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/folic-acid-for-the-prevention-of-neural-tube-defects-preventive-medication
January 10, 2017 - All included primary studies were observational, with attendant risks of misclassification and recall … between maternal folic acid supplementation compared with no use and childhood asthma, with a pooled relative … significant association with wheezing in childhood was associated with exposure in early pregnancy (relative … Both of the risks of bias described above (case ascertainment and recall) will reduce the differences … vitro fertilization; LRTI, lower respiratory tract infection; NR, not reported; OR, odds ratio; RR, relative
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/folic-acid-for-the-prevention-of-neural-tube-defects-preventive-medication-january-2017
January 10, 2017 - All included primary studies were observational, with attendant risks of misclassification and recall … between maternal folic acid supplementation compared with no use and childhood asthma, with a pooled relative … significant association with wheezing in childhood was associated with exposure in early pregnancy (relative … Both of the risks of bias described above (case ascertainment and recall) will reduce the differences … vitro fertilization; LRTI, lower respiratory tract infection; NR, not reported; OR, odds ratio; RR, relative
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/XGHwLrLfb_78ymEUwGF6jR
March 19, 2024 - differences between child maltreatment
intervention and control groups (68/1751 [3.9%] vs 55/1585 [3.5%];
relative … , risks of further harm to the child, or dissolution of families or
worsening of inequities (eTable 51 … No studies reported on
harms such as stigma, labeling, legal risks, risks of further harm to
the child … ED, emergency department; EPC, Evidence-based Practice Center;
KQ, key question; OR, odds ratio; RR, relative … The potential risks of false-positive findings (eg, fam-
ily separation, trauma for the child and parent
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/RPB3rmcS9CK_eXPdzXSxZg
July 01, 2010 - much higher
fracture rates than younger persons with the same bone
density because of increasing risks … However, in this study, DEXA of the femoral neck was
associated with a higher relative risk for hip … Bisphosphonates reduced vertebral fractures compared
with placebo (relative risk [RR], 0.66 [CI, 0.50 … Ten-year risks for major osteoporotic and hip fractures for U.S. white women estimated from the online … Highlighted risks equal or exceed the reference case
(woman aged 65 years with no risk factors: 9.3%
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/prevention-of-human-immunodeficiency-virus-hiv-infection-pre-exposure-prophylaxis
August 22, 2023 - or no PrEP (n = 18,172; relative risk [RR], 0.46 [95% CI, 0.33-0.66]). … 18,172; relative risk [RR], 0.46 [95% CI, 0.33-0.66]) (eFigure 1 in the JAMA Supplement), but statistical … ratio; IRR, incidence rate ratio; NR, not reported; OR, odds ratio; PrEP, preexposure prophylaxis; RR, relative … Molina et al, 46 2015) of event-driven PrEP, but vs placebo, is reported in the JAMA Supplement. c Relative … NR, not reported; OR, odds ratio; PrEP, preexposure prophylaxis; RCT, randomized clinical trial; RR, relative
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/uhtgkZVs_bpNJ4_G4fXUay
March 01, 2014 - Future improvements in risk assessment tools will help cli-
nicians better individualize patients’ risks … Overdiagnosis of lung cancer
and the risks of radiation are real harms, although their
magnitude is uncertain … The relative risk for all-cause mortality in the DLCST was
1.46 (CI, 0.99 to 2.15). … When these 3 fair- or good-quality trials were com-
bined in a meta-analysis, the relative risk for lung … exposure, family
history, and history of other lung diseases are important
when assessing patients’ risks
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/vTJ_Zj3TAkhx45wWUDtNyt
May 01, 2021 - The ACC/AHA risk estimator is, to date, the only
US-based CVD risk prediction tool that has published … risk estimation tools. … (18 trials; n = 85 816; relative
risk [RR], 0.92 [95% CI, 0.87 to 0.98]; absolute risk difference
[ARD … for per-
sons at borderline risk, and recommend consideration of risk en-
hancers to refine risk assessments … Cardiovascular benefits and diabetes risks
of statin therapy in primary prevention: an analysis
from