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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/aspirin-use-prevent-cardiovascular-disease-colorectal-cancer-preventive-medication-2002
January 15, 2002 - In PHS, aspirin reduced the relative risk for myocardial infarction for patients aged 70 to 84 years … Relative risks were 0.75 for patients aged 50 to 59 years and 0.61 for patients aged 60 to 64 years. … In PHS, patients who were taking aspirin and had SBP greater than 150 mm Hg had a relative risk of 0.65 … for myocardial infarction, compared with relative risks of 0.55 for those with SBP between 130 and 149 … The summary relative risk for hemorrhagic stroke with aspirin use was 1.84 (95 percent CI, 1.24 to 2.74
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-cancer--brca-testing-ovarian-cancer-screeni
September 15, 2005 - risks for breast and ovarian cancer in moderate- and high-risk groups. … All chemoprevention trials reported relative risk (RR) estimates, and the logarithm of the RR (logRR) … Sampling Distribution for Relative Risk
When developing the outcomes table, the estimates of relative … Risk
(95% CI)
Type
Treat-
ment
Group, n
Placebo
Group, n
Relative Risk … Relative Risks for Breast Cancer in Chemoprevention Trials
Error bars represent 95% CIs.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-and-ovarian-cancer-brca-testing-screening-2005
September 15, 2005 - risks for breast and ovarian cancer in moderate- and high-risk groups. … All chemoprevention trials reported relative risk (RR) estimates, and the logarithm of the RR (logRR) … Sampling Distribution for Relative Risk
When developing the outcomes table, the estimates of relative … Risk
(95% CI)
Type
Treat-
ment
Group, n
Placebo
Group, n
Relative Risk … Relative Risks for Breast Cancer in Chemoprevention Trials
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January 01, 2002 - Age
In PHS, aspirin reduced the relative risk for
myocardial infarction for patients aged 70 to 84
years … Relative risks were 0.75 for patients aged 50 to 59
years and 0.61 for patients aged 60 to 64 years. … In PHS, patients
who were taking aspirin and had SBP greater than
150 mm Hg had a relative risk of 0.65 … for
myocardial infarction, compared with relative risks
of 0.55 for those with SBP between 130 and … The summary relative risk for hemorrhagic
stroke with aspirin use was 1.84 (95% CI, 1.24 to
2.74).
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-medications-for-risk-reduction-2013
September 15, 2013 - that treatment with tamoxifen or raloxifene can significantly reduce the relative risk (RR) for invasive … Breast Cancer Prevention Trial; IBC = invasive breast cancer; WHI = Women's Health Initiative; RR = relative … Breast Cancer Prevention Trial; IBC = invasive breast cancer; WHI = Women's Health Initiative; RR = relative … Breast Cancer Prevention Trial; IBC = invasive breast cancer; WHI = Women's Health Initiative; RR = relative … Breast Cancer Prevention Trial; IBC = invasive breast cancer; WHI = Women's Health Initiative; RR = relative
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-bleeding-risks-with-aspirin-use/aspirin-to-prevent-cardiovascular-disease-and-cancer
April 11, 2016 - outcome, we calculated a range of expected event rates after aspirin intervention using the pooled relative … events will vary depending on individual baseline bleeding risks. … why persons with these risks have been excluded from trials. … Level †
Baseline Risk for Outcome,
events per 1000 person-years
Relative Risk (95% CI)
Events … ¶ Using cohort baseline risk and trial relative risks to estimate events caused or prevented.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-bleeding-risks-with-aspirin-use/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
April 11, 2016 - outcome, we calculated a range of expected event rates after aspirin intervention using the pooled relative … events will vary depending on individual baseline bleeding risks. … why persons with these risks have been excluded from trials. … Level †
Baseline Risk for Outcome,
events per 1000 person-years
Relative Risk (95% CI)
Events … ¶ Using cohort baseline risk and trial relative risks to estimate events caused or prevented.
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June 03, 2019 - below 1 after 16 or more years of
follow-up (relative risk, 0.79). … The
relative risks by year of observation (including trial plus
follow-up time) are shown in the Figure … Both of these trials reported relative risk re-
ductions among women 65 to 74 years of age (relative … (50),
1997
No 5 Swedish trials Weighted relative
risks
12.8 0.77 (0.59–1.01)
Nyström et al.
(32), … Relative risk was calculated as
exp(�).
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/cTa7Hs56-yj4kCr7yXLdRm
July 01, 1994 - Using the relative risks reported
by Kerlikowske and colleagues (16), we can estimate that
a family … Calculated from relative risk
estimates and ovarian cancer incidence data from the SEER (Surveillance … associated
with contraceptive pill use; both found similar relative
risks of approximately 0.65 associated … ; both
studies found a relative risk of approximately 0.5 after 5
years of use.
3.11 Parity has also … 50% (that is, a
relative risk of 0.5) for any pregnancy, with decreasing
risk associated with an increasing
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cardiovascular-disease-enhanced-risk-assessment-non-traditional-risk-factors
September 26, 2024 - disease risk assessment without these risk markers? … What are other risk markers used in enhanced cardiovascular disease risk assessment and what is their … How do 10-year risk scores compare between the two models? … integrated discrimination improvement), calibration (e.g., agreement between observed and predicted risks … ), and decision curve analysis
KQs 3, 5: Serious adverse events from risk factor assessment or risk
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/cardiovascular-disease-enhanced-risk-assessment-non-traditional-risk-factors
April 25, 2024 - multivariate cardiovascular disease risk assessment without these risk markers? … What are other risk markers used in enhanced cardiovascular disease risk assessment and what is their … assessment:
Base model risk assessment (e.g., PREVENT, PCE, FRS) + CAC score
Base model risk assessment … integrated discrimination improvement), calibration (e.g., agreement between observed and predicted risks … ), and decision curve analysis
KQs 3, 5: Serious adverse events from risk factor assessment or risk
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/j69Hq5ALvzg74e-ngkzSep
April 01, 2016 - outcome, we calcu-
lated a range of expected event rates after aspirin in-
tervention using the pooled relative … Baseline Estimates of Major Bleeding Risks
(Trial vs. … Risk for Outcome,
events per 1000 person-years
Relative Risk (95% CI) Events Caused per 1000
Person-Years … as reported by included cohort studies.
¶ Using cohort baseline risk and trial relative risks to estimate … why persons with these risks have
been excluded from trials.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-cancer-screening-2002
September 03, 2002 - Data Synthesis: For studies of fair quality or better, the summary relative risk was 0.84 (95% CrI, … follow-up (relative risk, 0.79). … The relative risks by year of observation (including trial plus follow-up time) are shown in the Figure … Both of these trials reported relative risk reductions among women 65 to 74 years of age (relative risk … Relative risk was calculated as exp(β).
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary21/vitamin-supplementation-to-prevent-cancer-and-cvd-counseling
February 03, 2014 - For all cases, we analyzed unadjusted relative risks based on the number of events and nonevents. … The pooled unadjusted relative risk was 0.98 (95% CI, 0.91 to 1.04). … RR = relative risk.
Return to Table of Contents
Figure 2. … RR = relative risk.
Return to Table of Contents
Figure 3. … RR = relative risk.
Return to Table of Contents
Appendix Table 1.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary21/vitamin-supplementation-to-prevent-cancer-and-cvd-counseling-february-2014
February 03, 2014 - For all cases, we analyzed unadjusted relative risks based on the number of events and nonevents. … The pooled unadjusted relative risk was 0.98 (95% CI, 0.91 to 1.04). … RR = relative risk.
Return to Table of Contents
Figure 2. … RR = relative risk.
Return to Table of Contents
Figure 3. … RR = relative risk.
Return to Table of Contents
Appendix Table 1.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/uPbfDukSXmFDWq8FDwTgKj
July 03, 2018 - Clinical Summary: Risk Assessment for Cardiovascular Disease With Nontraditional Risk Factors … Clinical Summary: Risk Assessment for Cardiovascular Disease With Nontraditional Risk Factors
Population … Grade: I (insufficient evidence)
Risk Assessment
Several traditional risk factors are associated … Risk factors can be combined in many w ays to
classify a person's risk for a CVD event. … CVD risk assessment in the United States has been generally based on the Framingham
Risk Score and the
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September 01, 2002 - density testing to identify fracture risks, effectiveness
of treatment in reducing fracture risk, and … This was
comparable to the magnitude of the relative risks of
most of the other significant predictors … 3,723 participants
(dosage 10 to 40 mg/d; weighted relative risk, 0.51;
CI, 0.38-0.69). … by 70% (relative
risk, 1.7). … risk for hip fracture 0.63 0.63 0.63 0.63 0.63 0.63
with treatment
Relative risk for vertebral 0.52
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www.uspreventiveservicestaskforce.org/uspstf/draft-update-summary/cardiovascular-disease-enhanced-risk-assessment-non-traditional-risk-factors
September 19, 2024 - Share to WhatsApp
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Enhanced Risk … See Current Final Recommendation Statement for Cardiovascular Disease: Risk Assessment With Nontraditional … Risk Factors(2018)
Final Research Plan
Supporting Evidence
Related Resources & Tools
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
September 28, 2021 - Aspirin use was significantly associated with lower risk of preeclampsia (pooled relative risk [RR], … Pooled estimates of the relative risks of health outcomes associated with aspirin use were generated … .12), or fetal intracranial bleeding (P = .34), and the relative risks in the increased-risk population … , No. of studies (No. analyzed) a
Pooled RR, random-effects model (95% CI) b
I 2 , %
τ 2
Relative … risk, range
ARD
Relative risk, median (IQR)
ARD (range)
Perinatal mortality
15 (15,527
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-medications-for-risk-reduction-2002
July 08, 2002 - Risk for breast cancer. … Risk for adverse effects. … The relative risk reduction for breast cancer was 0.94 (95 percent CI, 0.59-1.43) for the Royal Marsden … significant difference in incidence between the tamoxifen and placebo groups in this age group. 7 The relative … Weighing the risks and benefits of tamoxifen treatment for preventing breast cancer.