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Showing results for "risk".

21. Draft Research Plan: Enhanced Risk Assessment for Cardiovascular Disease: Coronary Artery Calcium Scoring | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/cardiovascular-disease-enhanced-risk-assessment-non-traditional-risk-factors
    April 25, 2024 - multivariate cardiovascular disease risk assessment without these risk markers? … What are other risk markers used in enhanced cardiovascular disease risk assessment and what is their … assessment: Base model risk assessment (e.g., PREVENT, PCE, FRS) + CAC score Base model risk assessment … integrated discrimination improvement), calibration (e.g., agreement between observed and predicted risks … ), and decision curve analysis KQs 3, 5: Serious adverse events from risk factor assessment or risk

22. Final Research Plan: Enhanced Risk Assessment for Cardiovascular Disease: Coronary Artery Calcium Scoring | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cardiovascular-disease-enhanced-risk-assessment-non-traditional-risk-factors
    September 26, 2024 - disease risk assessment without these risk markers? … What are other risk markers used in enhanced cardiovascular disease risk assessment and what is their … How do 10-year risk scores compare between the two models? … integrated discrimination improvement), calibration (e.g., agreement between observed and predicted risks … ), and decision curve analysis KQs 3, 5: Serious adverse events from risk factor assessment or risk

23. Evidence Summary: Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
    September 28, 2021 - Aspirin use was significantly associated with lower risk of preeclampsia (pooled relative risk [RR], … Pooled estimates of the relative risks of health outcomes associated with aspirin use were generated … .12), or fetal intracranial bleeding (P = .34), and the relative risks in the increased-risk population … , No. of studies (No. analyzed) a Pooled RR,  random-effects model (95% CI) b I 2 , % τ 2 Relative … risk, range ARD Relative risk, median (IQR) ARD (range) Perinatal mortality 15 (15,527

24. Final Research Plan: Cardiovascular Disease: Risk Assessment With Nontraditional Risk Factors | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cardiovascular-disease-screening-using-nontraditional-risk-assessment
    September 03, 2015 - factors alone, does risk assessment of asymptomatic adults using nontraditional risk factors—followed … Does use of nontraditional risk factors in addition to traditional risk factors to predict cardiovascular … disease risk improve measures of calibration, discrimination, and risk reclassification? … Does treatment guided by nontraditional risk factors in addition to traditional risk factors lead to … area under the curve, c-statistic), and calibration (e.g., agreement between observed and predicted risks

25. Risk Assessment for Cardiovascular Disease With Nontraditional Risk Factors: US Preventive Services Recommendation Statement (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/6cRgd5whkAvSGESSQsrQLR
    January 01, 2020 - Statement Risk Assessment for Cardiovascular Disease With Nontraditional Risk Factors US Preventive … Risk Score, incorporates hsCRP level into its risk calculation. … at intermediate risk. … year risk of 7.5% or greater are considered at high risk.4 The distribution of estimated CVD risk in … risk factors improves reclassifica- tion in intermediate-risk groups.

26. Archived: Breast Cancer: Medications for Risk Reduction | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-medications-for-risk-reduction-2002
    July 08, 2002 - Risk for breast cancer. … Risk for adverse effects. … The relative risk reduction for breast cancer was 0.94 (95 percent CI, 0.59-1.43) for the Royal Marsden … significant difference in incidence between the tamoxifen and placebo groups in this age group. 7 The relative … Weighing the risks and benefits of tamoxifen treatment for preventing breast cancer.

27. Screening for Postmenopausal Osteoporosis: A Summary of the Evidence (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/2kM7LY6ccceVo8bmdUXhYm
    September 01, 2002 - density testing to identify fracture risks, effectiveness of treatment in reducing fracture risk, and … This was comparable to the magnitude of the relative risks of most of the other significant predictors … 3,723 participants (dosage 10 to 40 mg/d; weighted relative risk, 0.51; CI, 0.38-0.69). … by 70% (relative risk, 1.7). … risk for hip fracture 0.63 0.63 0.63 0.63 0.63 0.63 with treatment Relative risk for vertebral 0.52

28. Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Updated Modeling Study for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/MLeu_yFpPwzcZwKG6fw5ZY
    April 26, 2022 - In all scenarios, non-CRC benefits and harms were assumed to take effect immediately, and relative risks … of Effects of Using Low-Dose (≤100 mg/d) Aspirin for Primary Prevention of CRC and CVD Parameter Relative … was lower and had a narrower confidence interval compared with the corre- sponding finding in 2016 (relative … for CRC incidence and affects fatal major gastrointestinal bleeding risks. … constant over time, but life- time net benefits of aspirin would be higher if these relative risks de

29. C-Reactive Protein as a Risk Factor for Coronary Heart Disease: A Systematic Review and Meta-analyses for the U.S. Preventive Services Task Force (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/khUSqr94jqWPErt9ZRnQ95
    October 01, 2009 - For good studies that adjusted for all Framingham risk variables, the summary estimate of relative risk … CRP level was positively associated with incident CHD events in 23 of the 24 cohorts, with adjusted relative … risks that ranged from 0.98 to 2.61. … The relative risk was 1.58 (CI, 1.37 to 1.83) for high versus low CRP levels (Figure 1) and 1.22 (CI, … The relative risk was 1.53 (CI, 1.36 to 1.73) for high versus low CRP levels and 1.20 (CI, 1.12 to 1.29

30. Archived: C-Reactive Protein as a Risk Factor for Coronary Heart Disease: A Systematic Review and Meta-analyses for the U.S. Preventive Services Task Force: Coronary Heart Disease: Screening Using Non-Traditional Risk Factors | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/c-reactive-protein-as-a-risk-factor-for-coronary-heart-disease-a-systematic-review-and-meta-analyses-for-the-us-preventive-services-task-force/coronary-heart-disease-screening-using-non-traditional-risk-factors-2009
    July 15, 2008 - For good studies that adjusted for all Framingham risk variables, the summary estimate of relative risk … CRP level was positively associated with incident CHD events in 23 of the 24 cohorts, with adjusted relative … risks that ranged from 0.98 to 2.61. … factors or calculated a Framingham risk score. 33 , 42 , 44-46 , 52 , 55-56 , 60-61 The relative risk … The relative risk was 1.53 (CI, 1.36 to 1.73) for high versus low CRP levels and 1.20 (CI, 1.12 to 1.29

31. Archived: Evidence Summary: Osteoporosis: Screening, 2002 | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/osteoporosis-screening-2002
    September 17, 2002 - density testing to identify fracture risks, effectiveness of treatment in reducing fracture risk, and … This was comparable to the magnitude of the relative risks of most of the other significant predictors … Risk Factor Relative Risk (95% confidence interval) References Age: per 2 years … risk for hip fracture with treatment 0.63 0.63 0.63 0.63 0.63 0.63 Relative risk for … Poor-fair: difficult to know how risks impact individual patients.

32. Evidence Gaps Research Taxonomy Table: Screening for IPV and Caregiver Abuse in Older Adults (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/yj6JY8HJZtbnv5qDPxS3PX
    Comparison Outcomes/ Timing Setting Studies are needed to assess the accuracy of screening tools in at-risk … negative predictive values, positive and negative likelihood ratios, diagnostic odds ratios, and relative … risks for future abuse Feasible for use in U.S. … negative predictive values, positive and negative likelihood ratios, diagnostic odds ratios, and relative … risks for future abuse Feasible for use in U.S.

33. Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/ph_fauqHQjmrSqPAWKrARA
    September 28, 2021 - Aspirin use was significantly associated with lower risk of preeclampsia (pooled relative risk [RR], … Pooled estimates of the relative risks of health outcomes associ- ated with aspirin use were generated … Pooled analysis, No. of studies (No. analyzed)a Pooled RR, random-effects model (95% CI)b I2, % τ2 Relative … risk, range ARD Relative risk, median (IQR) ARD (range) Perinatal mortality 15 (15 527) 11 (13 860 … ), or fetal intracranial bleeding (P = .34), and the relative risks in the increased-risk population

34. Evidence Summary: Cardiovascular Disease: Risk Assessment With Nontraditional Risk Factors | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary--html/cardiovascular-disease-screening-using-nontraditional-risk-assessment
    July 10, 2018 - For the Framingham Risk Score–based analyses, which used 3 risk strata, the top 2 risk strata (10%-20% … Combining risk markers improves cardiovascular risk prediction in women. … Comparison of novel risk markers for improvement in cardiovascular risk assessment in intermediate-risk … POPADAD, Prevention of Progression of Arterial Disease and Diabetes; RCT, randomized clinical trial; RR, relative … risk.

35. Evidence Summary: BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing
    August 20, 2019 - Importance: Pathogenic mutations in breast cancer susceptibility genes BRCA1 and BRCA2 increase risks … In 8 RCTs (n = 54,651), tamoxifen (relative risk [RR], 0.69 [95% CI, 0.59-0.84]; 4 trials), raloxifene … Two studies indicated women have less understanding of their risks after genetic counseling, 64 , 70 … for primary care settings that evaluate individual risks can accurately guide referrals for genetic … Ovarian Cancer Research Group Netherlands; HR, hazard ratio; NA, not applicable; NR, not reported; RR, relative

36. Archived: Reducing Risk for Mother-to-Infant Transmission of Hepatitis C Virus: A Systematic Review for the U.S. Preventive Services Task Force: Hepatitis C: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/reducing-risk-for-mother-to-infant-transmission-of-hepatitis-c-virus-a-systematic-review-for-the-us-preventive-services-task-force/hepatitis-c-screening-2013
    November 15, 2012 - Although antiviral therapies are contraindicated in pregnancy because of teratogenic risks, prenatal … after vaginal or emergent cesarean delivery compared with no cases after 12 elective cesarean births (relative … ratio, 6.7 [CI, 1.1 to 36]), but another, larger good-quality study ( n  = 724) found no association (relative … Paediatric Hepatitis C Virus Network; HCV = hepatitis C virus; NR = not reported; OR = odds ratio; RR = relative … risk; SD = standard deviation

37. Recommendation: Cardiovascular Disease: Risk Assessment With Nontraditional Risk Factors | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/cardiovascular-disease-screening-using-nontraditional-risk-assessment
    July 10, 2018 - Risk factors can be combined in many ways to classify a person's risk for a CVD event. … Risk Score, incorporates hsCRP level into its risk calculation. … at intermediate risk. … year risk of 7.5% or greater are considered at high risk. 4 The distribution of estimated CVD risk in … 7.5% for increased risk.

38. Recommendation: Enhanced Risk Assessment for Cardiovascular Disease: Coronary Artery Calcium Scoring | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/draft-update-summary/cardiovascular-disease-enhanced-risk-assessment-non-traditional-risk-factors
    September 19, 2024 - Share to WhatsApp Share to Email Print Enhanced Risk … See Current Final Recommendation Statement for Cardiovascular Disease: Risk Assessment With Nontraditional … Risk Factors(2018) Final Research Plan Supporting Evidence Related Resources & Tools

39. Archived: Evidence Summary: Aspirin Use to Prevent Cardiovascular Events: Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin-to-prevent-cardiovascular/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
    April 11, 2016 - In analyses of all doses, aspirin reduced the risk for nonfatal myocardial infarction (MI) (relative … risks (RRs) from the included CVD primary prevention trials evaluating aspirin doses of 100 mg or less … Bleeding risks with aspirin use for primary prevention in adults: a systematic evidence review for the … Figure 1 displays a forest plot of studies reporting the relative risk for the intervention group versus … Figure 2 displays a forest plot of studies reporting the relative risk for the intervention group versus

40. Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/MzHhsgTBL37rRvvJfkfgMZ
    August 20, 2019 - MD IMPORTANCE Pathogenic mutations in breast cancer susceptibility genes BRCA1 and BRCA2 increase risks … In 8 RCTs (n = 54 651), tamoxifen (relative risk [RR], 0.69 [95% CI, 0.59-0.84]; 4 trials), raloxifene … trials), and aromatase inhibitors (RR, 0.45 [95% CI, 0.26-0.70]; 2 trials) were associated with lower risks … Ovarian Cancer Research Group Netherlands; HR, hazard ratio; NA, not applicable; NR, not reported; RR, relative … Cancer risks for BRCA1 and BRCA2 mutation carriers: results from prospective analysis of EMBRACE.