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  1. www.uspreventiveservicestaskforce.org/home/getfilebytoken/JcwfLrEqaaxP6DPEQvxgUs
    February 18, 2020 - , similar relative risk estimates were observed among those classified at a higher vs lower CVD event … risk.10,23 Given similar relative risk reductions, the absolute magnitude of benefit that an intervention … It is possible that the relative risk reduction in this group is higher than in adults with a lower LDL-C … =articlePDF%26utm_content=jama.2016.15450 without severe dyslipidemia at baseline.6 Given similar relative … Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from
  2. www.uspreventiveservicestaskforce.org/uspstf/recommendation/child-maltreatment-primary-care-interventions
    March 19, 2024 - intervention, there were no group differences between intervention and control groups (3.9% vs 3.5%; relative … yielded inconsistent results. 1 In 1 trial, there were no differences reported in physical abuse (relativerisk, 1.45 [95% CI, 0.58-3.62]) or neglect (relative risk, 2.79 [95% CI, 0.98-7.91) between the intervention … “disadvantaged families” to prevent child maltreatment and recommends against screening, citing the risks … or legal risks related to Child Protective Services) and to engagement in preventive interventions (
  3. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/breast-cancer-medication-use-reduce-risk
    March 21, 2024 - Print in progress Final Research Plan Breast Cancer: Medication to Reduce Risk … What are the harms of medications used to reduce primary breast cancer risk? … breast cancer, including clinical risk factors or prediction models? … What are the perspectives and preferences of patients on breast cancer risk and the use of risk-reducing … of risk-reducing medications?
  4. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd
    November 24, 2020 - Interventions were associated with a lower risk of cardiovascular events (pooled relative risk, 0.80 … Studies rated as poor were excluded. 14 Poor-quality studies typically had several major risks of bias … Behavioral counseling was associated with lower risk of the composite outcomes of any CVD events (risk … Population risks of 7.5% and 10% translate to numbers needed to treat of 67 (95% CI, 49 to 103) and 50 … men at high cardiovascular risk.
  5. www.uspreventiveservicestaskforce.org/home/getfilebytoken/sZN5HHS8w5Sar6bBPabsaB
    June 01, 2008 - �55 years and 1 addi- tional cardiovascular risk factor) experienced a 25% relative risk reduction ( … In that trial, the diabetes subgroup experienced a 51% relative risk reduction in cardiovascular events … for major cardiovascular events in persons with diabetes (relative risk, 0.64 [CI, 0.46 to 0.89]) but … Persons with diabetes had a similar reduction in cardiovascular events (relative risk reduction, 27% … Data from the Diabetes Prevention Program (36). ‡ Relative risk reduction, 31% with adherence rates (
  6. www.uspreventiveservicestaskforce.org/home/getfilebytoken/cJSpoZqW2M7czx_-GeTdtE
    May 01, 2004 - prospective risk factors for a suicide.8 Although prior suicide attempts are a key risk factor, two-thirds … Still, deliberate self-harm is a recurrent behavior with important long-term risks. … and clinical reasons, excluded patients at the highest risk. … to risk severity. … Screening for Suicide Risk.
  7. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/breast-cancer-medication-use-reduce-risk
    December 28, 2023 - Print in progress Draft Research Plan Breast Cancer: Medication to Reduce Risk … What are the harms of medications used to reduce primary breast cancer risk? … What is the accuracy of different approaches for identifying individuals at increased risk of primary … breast cancer, including clinical risk factors or prediction models? … What are the perspectives and preferences of patients on breast cancer risk and the use of risk-reducing
  8. JAMA (pdf file)

    www.uspreventiveservicestaskforce.org/home/getfilebytoken/ymZSPeLcwZ9rxTC-7zdWbp
    July 11, 2022 - Clinical Risk Assessment for Preeclampsiaa Risk level Risk factors Recommendation Highb • History of … It is strengthened by new evidence from additional trials demonstrating reduced risks of perinatal mortality … Assess Risk. … It is strengthened by new evi- dence from additional trials supporting reduced risks of perinatal mortality … The USPSTF found evidence of a reduction in risk for preterm birth (pooled relative risk [RR], 0.80 [
  9. www.uspreventiveservicestaskforce.org/uspstf/recommendation/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
    September 28, 2021 - It is strengthened by new evidence from additional trials demonstrating reduced risks of perinatal mortality … Assess Risk. … Pregnant persons are at high risk for preeclampsia if they have 1 or more of the following risk factors … It is strengthened by new evidence from additional trials supporting reduced risks of perinatal mortality … The USPSTF found evidence of a reduction in risk for preterm birth (pooled relative risk [RR], 0.80 [
  10. www.uspreventiveservicestaskforce.org/uspstf/recommendation/falls-prevention-in-older-adults-counseling-and-preventive-medication-2012
    May 15, 2012 - management of identified risks to prevent falls. … Multifactorial risk assessment with comprehensive management of identified risks has at least a small … assessment with comprehensive management of identified risks have at least a small benefit in preventing … of identified risks has a small net benefit in preventing falls in older adults. … for falling after 12 months compared with usual care (pooled relative risk [RR], 0.89 [95% CI, 0.76
  11. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary2/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd-august-2014
    August 26, 2014 - 0.12 mmol/L (CI, 0.18 to 0.05 mmol/L) (2.08 mg/dL [CI, 3.29 to 0.88 mg/dL]), diabetes incidence by a relative … in a composite measure of all CVD events at 6.6 years of follow-up (relative risk, 0.71 [95% CI, 0.51 … , as well as trends in the distribution of CVD and CVD risk factors over time. … Effect on haemostatic variables and other coronary risk factors. … , and metabolic risk factors.
  12. www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/perinatal-depression-interventions-to-prevent
    April 22, 2025 - initiated interventions during the second or third trimester of pregnancy. 2 Ongoing assessment of risks … interventions were associated with a 17% reduction in the likelihood of perinatal depression (pooled relativerisk [RR], 0.83 [95% CI, 0.72 to 0.95]; 21 studies; n=4,974; I 2 =0.0). … , unselected populations (31% vs. 5% risk reduction, respectively). … Depression during pregnancy: a risk factor for adverse neonatal outcomes?
  13. www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication-november-2016
    November 13, 2016 - CI, 0.63 to 0.78]). 6 Among the study populations, the proportion of CVD events prevented (ie, the relative … , similar relative risk estimates were observed among those classified at a higher vs lower CVD event … risk. 10 , 23 Given similar relative risk reductions, the absolute magnitude of benefit that an intervention … It is possible that the relative risk reduction in this group is higher than in adults with a lower LDL-C … Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from
  14. www.uspreventiveservicestaskforce.org/home/getfilebytoken/6LdjRdFR8Pj8KCrgLyaWZZ
    December 01, 2012 - should be considered for genetic counseling to further evaluate their potential risks. … their potential risks. … can- cer cases diagnosed in the screening group compared with the control group (212 vs. 176 cases; relative … cancer death rate (118 vs. 100 deaths; relative risk, 1.18 [CI, 0.82 to 1.71]) (4). … Prospective study using the risk of ovarian cancer algorithm to screen for ovarian cancer.
  15. www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/statin-use-in-adults-preventive-medication
    August 23, 2022 - risk estimation tools. … (18 trials; n = 85,816; relative risk [RR], 0.92 [95% CI, 0.87 to 0.98]; absolute risk difference [ARD … statin therapy and myopathy or rhabdomyolysis, although these events were uncommon, so the estimates of relative … discussion for persons at borderline risk, and recommend consideration of risk enhancers to refine risk … Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from
  16. www.uspreventiveservicestaskforce.org/uspstf/recommendation/aspirin-for-the-prevention-of-cardiovascular-disease-preventive-medication-2009
    March 15, 2009 - therapy should consider the overall risks for coronary heart disease and gastrointestinal bleeding. … Women The net benefit of aspirin depends on the initial risks for stroke and gastrointestinal bleeding … Shared decision making should be encouraged with women for whom the potential benefits and risks for … The WHS reported benefit with aspirin use in stroke reduction (relative risk [RR], 0.83 [95% CI, 0.69 … is sufficiently high for the benefits to outweigh the risks associated with treatment (a 10-year risk
  17. www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-and-ovarian-cancer-brca-testing-screening-2005
    September 15, 2005 - should be considered for genetic counseling to further evaluate their potential risks. … cancer in women without previous breast cancer. 38 , 39 A meta-analysis of these trials showed a relative … Four studies of prophylactic oophorectomy reported reduced risks for ovarian and breast cancer, 46-49 … Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2 . … The lifetime risks of breast cancer in Ashkenazi Jewish carriers of BRCA1 and BRCA2 mutations.
  18. www.uspreventiveservicestaskforce.org/uspstf/recommendation/osteoporosis-screening-2011
    January 15, 2011 - White women between the ages of 50 and 64 years with equivalent or greater 10-year fracture risks based … The FRAX tool also predicts 10-year fracture risks for black, Asian, and Hispanic women in the United … In general, estimated fracture risks in nonwhite women are lower than those for white women of the same … In a meta-analysis of 7 trials, the relative risk (RR) of vertebral fractures for bisphosphonates compared … Many comments pointed out a lack of clarity about how clinicians can estimate 10-year fracture risks
  19. www.uspreventiveservicestaskforce.org/home/getfilebytoken/b-rsH7WPpNC3uL9NeoXBfF
    May 08, 2018 - Pooled relative risks of incontinence with radical prostatectomy were 2.27 (95% CI, 1.82-2.84; I2 = 0.0% … difference; RCT, randomized clinical trial; RR, relative risk. a Conservative management encompasses … difference; RCT, randomized clinical trial; RR, relative risk. a Conservative management encompasses … difference; RCT, randomized clinical trial; RR, relative risk. a Conservative management encompasses … difference; RCT, randomized clinical trial; RR, relative risk. a Conservative management encompasses
  20. www.uspreventiveservicestaskforce.org/home/getfilebytoken/75ftPGW4rZ-3tdMQPstvDg
    August 01, 2012 - con- junction with comprehensive management of identified risks to prevent falls in community-dwelling … assessment with comprehensive management of identified risks to prevent falls. … Multifactorial risk assessment with comprehensive management of identified risks has at least a small … - ment of identified risks has a small net benefit in prevent- ing falls in older adults. … for falling after 12 months compared with usual care (pooled relative risk [RR], 0.89 [95% CI, 0.76

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