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  1. www.uspreventiveservicestaskforce.org/home/getfilebytoken/RRALFxUMfP7TXazQY32ZbG
    June 12, 2018 - stratification using ECG plus traditional risk factors vs risk stratification using traditional risk … Clinical Trials Reporting Health Outcomes (KQ1) Favors Screening Favors Not Screening 0.02 8.01.00.1 Relative … Persons Without Event, No.Source Primary composite outcome Relative Risk (95% CI) 28 26288 289DYNAMIT … Relative risks (RRs) and 95% CIs calculated using the numbers of events reported by the trials. … g Required cardiovascular risk score of �10% for eligibility, risk determined according to Italian risk
  2. www.uspreventiveservicestaskforce.org/home/getfilebytoken/crPsNJ_R5SFnJhuT2CEpkr
    March 01, 2019 - Warfarin (mean, 1.5 years) was associated with a reduced risk of ischemic stroke (relative risk [RR], … For KQ4 and KQ5, relative risks (RRs) and 95% CIs were calculated for all-cause mortality, cardiovascular-related … Relative Risk of All-Cause Mortality and Selected Health Outcomes for Warfarin Compared With Controls … Relative Risk of Major Bleeding, Major Extracranial Bleeding, and Intracranial Hemorrhage for Warfarin … Compared With Controls (KQ5) Weight, % Favors Warfarin Favors Control Relative Risk (95% CI) Mean
  3. www.uspreventiveservicestaskforce.org/home/getfilebytoken/wBcZfBcVp8N3-cyT3Peysv
    April 01, 2016 - In analyses of all doses, aspirin reduced the risk for nonfatal myocardial infarction (MI) (relative … tiplying the sample size of the control group by the mean follow-up years), thereby assuming constant risksrisks (RRs) from the included CVD pri- mary prevention trials evaluating aspirin doses of 100 mg or … is higher than that for the aver- age population and high enough to outweigh the seri- ous bleeding risks … Bleeding risks with aspirin use for primary prevention in adults: a systematic evidence review for the
  4. www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/child-maltreatment-primary-care-interventions
    March 19, 2024 - intervention, there were no group differences between intervention and control groups (3.9% vs 3.5%; relative … yielded inconsistent results. 1 In 1 trial, there were no differences reported in physical abuse (relativerisk, 1.45 [95% CI, 0.58-3.62]) or neglect (relative risk, 2.79 [95% CI, 0.98-7.91) between the intervention … “disadvantaged families” to prevent child maltreatment and recommends against screening, citing the risks … or legal risks related to Child Protective Services) and to engagement in preventive interventions (
  5. www.uspreventiveservicestaskforce.org/uspstf/recommendation/hypertensive-disorders-pregnancy-screening
    September 19, 2023 - factor. 34 Clinicians should also be aware of the risks of poor health outcomes for populations at … risk. … −1.58 days [95% CI, −8.10 to 4.94 days]), number of hypertensive disorders of pregnancy diagnoses (relative … of labor for any reason and for reasons related to hypertension or fetal distress. 1 , 38 , 41 , 42 Relativerisks for all these outcomes were close to or less than 1, with no statistically significant differences
  6. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary51/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
    April 08, 2014 - low-dose aspirin use (relative risk [RR], 0.81 [95% CI, 0.65 to 1.01]; I 2 = 0%), but the result was … Figure 1 is a forest plot depicting the relative risk for preterm birth after aspirin prophylaxis and … Figure 3 is a forest plot depicting the relative risk for preeclampsia after aspirin prophylaxis. … Appendix Figure 3 is a forest plot depicting the relative risk for perinatal mortality after aspirin … Appendix Figure 5 is a forest plot depicting the relative risk for intracranial fetal bleeding after
  7. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary51/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication-september-2014
    April 08, 2014 - low-dose aspirin use (relative risk [RR], 0.81 [95% CI, 0.65 to 1.01]; I 2 = 0%), but the result was … Figure 1 is a forest plot depicting the relative risk for preterm birth after aspirin prophylaxis and … Figure 3 is a forest plot depicting the relative risk for preeclampsia after aspirin prophylaxis. … Appendix Figure 3 is a forest plot depicting the relative risk for perinatal mortality after aspirin … Appendix Figure 5 is a forest plot depicting the relative risk for intracranial fetal bleeding after
  8. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/intimate-partner-violence-abuse-older-vulnerable-adults
    April 20, 2023 - risk of caregiver abuse and neglect? … and negative predictive values, positive and negative likelihood ratios, diagnostic odds ratios, and relativerisks for future abuse KQ 3: Psychosocial harms that result from screening, including labeling and … and negative predictive values, positive and negative likelihood ratios, diagnostic odds ratios, and relativerisks for future abuse KQ 3:  Psychosocial harms that result from screening, including labeling and
  9. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary27/breast-cancer-medications-for-risk-reduction-2013
    April 15, 2013 - Worry about side effects, belief that benefits were not worth the risks, and taking pills were cited … family member with breast cancer (20% vs. 9%) and believed that the benefits of tamoxifen outweigh the risks … because they inadequately described the population and follow-up 97 , provided estimates for 1-year risksRisks for some adverse outcomes and population subgroups were underestimated because of lack of statistical … Preferences of Women Evaluating Risks of Tamoxifen (POWER) study of preferences for tamoxifen for breast
  10. www.uspreventiveservicestaskforce.org/home/getfilebytoken/hhrqMCEgbsBMJ_Ppbcp4yJ
    January 14, 2025 - measured at the femoral neck.24,26 Risks predicted by FRAX alone and by BMD alone are similar, but both … thresholds at the individual level to account for additional risks (eg, fall risk) not considered in … The pooled relative risk (RR) for the effect of screening on hip fractures was 0.83 (95% CI, 0.73-0.93 … Relative risk estimates were imprecise and CIs were wide in all these studies.1,46 One cohort study of … Development of prognostic nomograms for individualizing 5-year and 10-year fracture risks.
  11. www.uspreventiveservicestaskforce.org/home/getfilebytoken/EGPJ5VSbLv4_cDB7fQBmGR
    May 01, 2014 - Suicide risk varies by age, sex, and race or ethnicity. … It is critical that more investigations on the benefits and risks of interventions targeting average- … and high-risk adolescents be conducted. … A single large trial of older primary care patients reported a 20% reduction in the relative risk for … for suicide and that physicians should screen for de- pression or suicidal risk in those with risk factors
  12. www.uspreventiveservicestaskforce.org/home/getfilebytoken/qX9C7hyCBCNRjptQNCa_37
    December 01, 2013 - Testing for BRCA-related Cancer in Women Assessing Genetic Risk for Cancer and Reducing Risk for BRCA-related … treatments aimed at reducing the risk for BRCA-related cancers. … For these women, risk assessment, genetic counseling and BRCA testing, and risk-reducing treatment … • Others, after learning about the benefits and risks, decide not to have the genetic test. … The potential harms of risk assessment and genetic testing for women who are at risk are small to moderate
  13. www.uspreventiveservicestaskforce.org/home/getfilebytoken/_nVeFxDCT9L-_cnDf_V3fK
    July 17, 2018 - Nontraditional Risk Factors in Cardiovascular Disease Risk Assessment: Updated Evidence Report and Systematic … For the Framingham Risk Score–based analyses, which used 3 risk strata, the top 2 risk strata (10%-20% … POPADAD, Prevention of Progression of Arterial Disease and Diabetes; RCT, randomized clinical trial; RR, relative … Combining risk markers improves cardiovascular risk prediction in women. … Comparison of novel risk markers for improvement in cardiovascular risk assessment in intermediate-risk
  14. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary17/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing-2013
    December 15, 2013 - Mutations in breast cancer susceptibility genes ( BRCA1 and BRCA2 ) are associated with increased risks … Force (USPSTF) recommended in 2005 that women whose family histories are associated with increased risks … Deleterious mutations in the BRCA1 and BRCA2 genes are associated with increased risks for breast … For example, women with BRCA1 mutations have higher risks for ovarian cancer than those with BRCA2 … Each step requires careful interpretation of information, consideration of risks, weighing of benefits
  15. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary20/suicide-risk-in-adolescents-adults-and-older-adults-screening
    April 15, 2013 - Psychotherapy did not reduce suicide attempts in adolescents at 6 to 18 months (relative risk, 0.99 [ … Thus, different age groups seem to have different treatment needs and risks. … Figure 1 displays a forest plot of the relative risk (RR) of suicide attempts in adult and adolescent … Figure 4 displays a forest plot of the relative risk (RR) of suicide attempts in enhanced usual care … Psychotherapy reduced the risk for suicide attempts by 32% (relative risk, 0.68 [95% CI, 0.56 to 0.83
  16. www.uspreventiveservicestaskforce.org/home/getfilebytoken/7ZSKduUYHWKe7q_tTY9xbF
    April 01, 2013 - A recent meta-analysis of tamoxifen trials indicated that risks for endometrial can- cer, deep venous … Worry about side effects, belief that benefits were not worth the risks, and taking pills were cited … family member with breast cancer (20% vs. 9%) and believed that the benefits of tamoxifen outweigh the risks … because they inadequately described the population and follow-up (97), provided estimates for 1-year risks … Preferences of Women Evaluating Risks of Tamoxifen (POWER) study of preferences for tamoxifen for breast
  17. www.uspreventiveservicestaskforce.org/uspstf/recommendation/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing-2013
    December 24, 2013 - ovarian cancer risk by 69% to 100% and breast cancer risk by 37% to 100% 9 . … Risks for breast, ovarian, and other types of BRCA-related cancer are greatly increased in patients who … influence medical management of the patient or relative, when potential benefits outweigh potential risks … predisposition requires informed consent that should encompass pretest education and counseling about the risks … Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case
  18. www.uspreventiveservicestaskforce.org/uspstf/recommendation/bacterial-vaginosis-pregnancy-prevent-preterm-delivery-screening-2001
    January 01, 2001 - D High-risk pregnant women The U.S. … (See Clinical Considerations for discussion of populations at high risk.) … among high-risk pregnant women. … consistently shown an association between BV and adverse pregnancy outcomes, including preterm delivery (relativerisks [RRs] ranging from 1.4 to 6.9), preterm premature rupture of membranes (RR=52.0 to 7.3), spontaneous
  19. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin-to-prevent-cancer/aspirin-to-prevent-cardiovascular-disease-and-cancer
    April 11, 2016 - Data Synthesis: In CVD primary prevention trials, cancer mortality (relative risk [RR], 0.96 [95% CI … Figure 3 displays two forest plots of studies reporting the relative risk for the intervention group … Appendix Figure 2 displays a forest plot of studies reporting the relative risk for the intervention … Appendix Figure 3 displays a forest plot of studies reporting the relative risk for the intervention … Appendix Figure 4 displays a forest plot of studies reporting the relative risk for the intervention
  20. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin-to-prevent-cancer/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
    April 11, 2016 - Data Synthesis: In CVD primary prevention trials, cancer mortality (relative risk [RR], 0.96 [95% CI … Figure 3 displays two forest plots of studies reporting the relative risk for the intervention group … Appendix Figure 2 displays a forest plot of studies reporting the relative risk for the intervention … Appendix Figure 3 displays a forest plot of studies reporting the relative risk for the intervention … Appendix Figure 4 displays a forest plot of studies reporting the relative risk for the intervention

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