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  1. www.uspreventiveservicestaskforce.org/home/getfilebytoken/MnkNvteY4Yg_8Jut4SayVN
    July 02, 2002 - but will depend on breast cancer risk, risk for potential harms, and individual patient preferences. … Risk for adverse effects. … The relative risk reduction for breast cancer was 0.94 (95% CI, 0.59 -1.43) for the Royal Marsden Hospital … significant difference in incidence between the tamoxifen and placebo groups in this age group.7 The relative … Weighing the risks and benefits of tamoxifen treatment for preventing breast cancer .
  2. www.uspreventiveservicestaskforce.org/uspstf/recommendation/ovarian-cancer-screening-2012
    September 15, 2012 - their potential risks. … should be considered for genetic counseling to further evaluate their potential risks. … ovarian cancer cases diagnosed in the screening group compared with the control group (212 vs. 176 cases; relative … cancer death rate (118 vs. 100 deaths; relative risk, 1.18 [CI, 0.82 to 1.71]) 4 . … Prospective study using the risk of ovarian cancer algorithm to screen for ovarian cancer.
  3. www.uspreventiveservicestaskforce.org/home/getfilebytoken/pnyU5fxhdBUtCdvJ3GyqzR
    March 01, 2007 - Data Synthesis: Regular use of aspirin reduced the incidence of colonic adenomas in RCTs (relative risk … The effect measure chosen for synthesis was the relative risk (RR). … reduction; NNTB � number needed to treat for benefit; OR � odds ratio; RR � relative risk. … Confounders Controlled for in the Studies’ Adjusted Relative Risk Estimates for the Incidence of Colorectal … Confounders Controlled for in the Studies’ Adjusted Relative Risk Estimates for the Incidence of Colorectal
  4. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-statins/statin-use-in-adults-preventive-medication-november-2016
    November 13, 2016 - For composite cardiovascular outcomes, relative risk estimates were very similar for men and women in … Although relative risk estimates across subgroups were similar, absolute benefits were greater in subgroups … Given similar relative risk estimates, the absolute benefits of statin therapy will be greater in populations … Statins: is it really time to reassess benefits and risks? … Risks associated with statin therapy: a systematic overview of randomized clinical trials.
  5. www.uspreventiveservicestaskforce.org/home/getfilebytoken/vxPM4Bo9RXZGUDH6MWnDht
    May 01, 2013 - in the likelihood of a suicide attempt or deliberate self-harm compared with usual care recipients (relative … Psy- chotherapy did not reduce suicide attempts in adolescents at 6 to 18 months (relative risk, 0.99 … 0.62 (0.33 to 1.13) 0.31 (0.12 to 0.78) 0.41 (0.04 to 3.82) 0.68 (0.56 to 0.83) (0.48 to 0.98) Relative … Psychotherapy reduced the risk for suicide attempts by 32% (relative risk, 0.68 [95% CI, 0.56 to 0.83 … Thus, different age groups seem to have different treatment needs and risks.
  6. www.uspreventiveservicestaskforce.org/home/getfilebytoken/_SfjkGNHBnLqn8ySe7kAdg
    April 01, 2016 - Results of Sensitivity Analysis: Results are most sensitive to the relative risk for hemorrhagic stroke … and CVD mortality but are affected by all relative risk estimates, baseline GI bleeding incidence and … No clear evidence was found that aspirin changes the relative risk (RR) for CVD death, fatal GI bleeding … , which corresponds with the data we used to inform community-based bleeding risks (47). … We did not account for heterogeneity in GI bleeding risks be- yond age and sex.
  7. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/brca-related-cancer-risk-assessment-genetic-counseling-testing
    April 11, 2024 - Email Print in progress Final Research Plan BRCA-Related Cancer: Risk … Clinically significant pathogenic mutations in the BRCA1 and BRCA2 genes associated with increased risk … In women with unknown carrier status for pathogenic BRCA1/2 mutations, does risk assessment, genetic … What are the optimal ages and intervals for risk assessment? 2b. … How does risk assessment for pathogenic BRCA1/2 mutations in women without BRCA1/2 -related cancer
  8. www.uspreventiveservicestaskforce.org/uspstf/document/decision-analysis-for-aspirin/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
    April 11, 2016 - Results of Sensitivity Analysis: Results are most sensitive to the relative risk for hemorrhagic stroke … and CVD mortality but are affected by all relative risk estimates, baseline GI bleeding incidence and … No clear evidence was found that aspirin changes the relative risk (RR) for CVD death, fatal GI bleeding … for heterogeneity in GI bleeding risks beyond age and sex. … Bleeding risks with aspirin use for primary prevention in adults: a systematic evidence review for the
  9. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/intimate-partner-violence-abuse-older-vulnerable-adults
    April 20, 2023 - risk of caregiver abuse and neglect? … and negative predictive values, positive and negative likelihood ratios, diagnostic odds ratios, and relativerisks for future abuse KQ 3: Psychosocial harms that result from screening, including labeling and … and negative predictive values, positive and negative likelihood ratios, diagnostic odds ratios, and relativerisks for future abuse KQ 3:  Psychosocial harms that result from screening, including labeling and
  10. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/intimate-partner-violence-and-abuse-of-elderly-and-vulnerable-adults-screening
    April 20, 2023 - risk of caregiver abuse and neglect? … and negative predictive values, positive and negative likelihood ratios, diagnostic odds ratios, and relativerisks for future abuse KQ 3: Psychosocial harms that result from screening, including labeling and … and negative predictive values, positive and negative likelihood ratios, diagnostic odds ratios, and relativerisks for future abuse KQ 3:  Psychosocial harms that result from screening, including labeling and
  11. www.uspreventiveservicestaskforce.org/home/getfilebytoken/R_cAa3AjFGQ2np_aQnzQGA
    February 11, 2025 - Screening was associated with reduced hip (pooled relative risk [RR], 0.83 [95% CI, 0.73-0.93]; 3 RCTs … of events/total (%) Screened ControlSource All Relative risk (95% CI) 3.724.5/11.54375 632/5405 ( … difference per 1000 (95% CI) 0.2 71 Pooled relative risk (95% CI) No. of studies No. of participants … With event TotalOutcomes Benefits of treatment (KQ4) Pooled relative risk (95% CI) Hip 6 98 12 055Bisphosphonates … ; RR, relative risk; SCORE, Simple Calculated Osteoporosis Risk Estimation; SOFSURF, Study of Osteoporotic
  12. www.uspreventiveservicestaskforce.org/home/getfilebytoken/JG6NmvasZ62BCsX7H7fpf9
    October 01, 2022 - Screening for Depression and Suicide Risk in Children and Adolescents The USPSTF recognizes … Clinician Summary of USPSTF Recommendation Screening for Depression and Suicide Risk in Children and … • All children aged 12 to 18 years are at risk of depression and should be screened. … However, there are some factors that increase the risk. … Some gender identities and sexual orientations may increase risk of depression.
  13. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/folic-acid-for-the-prevention-of-neural-tube-defects-preventive-medication
    August 01, 2023 - with folic acid supplementation taken before pregnancy (adjusted relative risk [aRR], 0.54 [95% CI, 0.31 … 2013. 6 The authors performed this stratified analysis because they found that the overall adjusted relative … new trials can be conducted on this topic New studies must rely on observational data with inherent risks … comparisons and outcomes 31-41 Variable measures of outcomes and exposure, all observation studies with risks … 31 , 33 , 34 , 40 , 41 Variable measures of outcomes and exposure, all observational studies with risks
  14. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/brca-related-cancer-risk-assessment-genetic-counseling-testing
    January 18, 2024 - Email Print in progress Draft Research Plan BRCA-Related Cancer: Risk … Genetic testing may be done on the index patient, a relative with cancer, or a relative with highest risk … In women with unknown carrier status for pathogenic BRCA1/2 mutations, does risk assessment, genetic … What are the optimal ages and intervals for risk assessment? 2b.   … What are the adverse effects of: 3a) risk assessment, 3b) genetic counseling, 3c) genetic testing, and
  15. www.uspreventiveservicestaskforce.org/home/getfilebytoken/bQNXFv9Q5uaAQvWH6B7VWV
    June 11, 2019 - (11 trials; relative risk [RR], 0.46 [95% CI, 0.33-0.66]; I2 = 67%; absolute risk reduction [ARD], − … Data Synthesis Meta-analysis was conducted to calculate pooled relative risks (RRs) for effects of PrEP … 0.73 (0.25-2.10) 0 Abbreviations: MSM, men who have sex with men; PrEP, preexposure prophylaxis; RR, relative … difference; ARR, adjusted relative risk; AUROC, area under the receiver operating characteristics curve … ; PrEP, preexposure prophylaxis; PWID, people who inject drugs; RCT, randomized clinical trial; RR, relative
  16. www.uspreventiveservicestaskforce.org/home/getfilebytoken/VpT-c4bnmvHFRPyKgPwb2Z
    December 01, 2010 - address the risks and deficiencies identified in the assessment (8). … Thus, primary analyses estimated relative risk for falling by using random-effects models (20, 21). … After 12 months, the relative risk for falling between the intervention group and usual care was 0.86 … affect the overall statistical significance for comprehensive interven- tions (relative risk, 0.88 [CI … risk reduction was attenuated but remained statistically significant (relative risk, 0.83 [CI, 0.71
  17. www.uspreventiveservicestaskforce.org/home/getfilebytoken/-97QgoUF_rpQSy-9yM9KCx
    November 24, 2020 - Interventions were associated with a lower risk of cardiovascular events (pooled relative risk, 0.80 … Studies rated as poor were excluded.14 Poor-quality studies typically had several major risks of bias … Behavioral counseling was associated with lower risk of the composite outcomes of any CVD events (risk … Population risks of 7.5% and 10% translate to numbers needed to treat of 67 (95% CI, 49 to 103) and 50 … men at high cardiovascular risk.
  18. www.uspreventiveservicestaskforce.org/home/getfilebytoken/BdMLHKcM_9Qs9C4z-X8GJY
    October 06, 2009 - Using Nontraditional Risk Factors in Coronary Heart Disease Risk Assessment: Clinical Summary of U.S. … Treatment to prevent CHD events by modifying risk factors is currently based on the Framingham risk model … If the classification of individuals at intermediate risk could be improved by using additional riskRisk factors not currently part of the Framingham model (nontraditional risk factors) include high sensitivity … and guide risk-based preventive therapy.
  19. www.uspreventiveservicestaskforce.org/uspstf/recommendation/screening-depression-suicide-risk-adults
    June 20, 2023 - Ongoing assessment of risks that may develop during pregnancy and the postpartum period is also a reasonable … However, there are some factors that increase risk. … Ongoing assessment of risks that may develop during pregnancy and the postpartum period is also a reasonable … Epidemiology and natural history of suicide risk. … Potential harms of suicide risk interventions.
  20. www.uspreventiveservicestaskforce.org/home/getfilebytoken/bF_Y9vcT3eNPdHjTxPZsUZ
    April 17, 2023 - Ongoing assessment of risks that may develop during pregnancy and the postpartum period is also a reasonable … Ongoing assessment of risks that may develop during pregnancy and the post- partum period is also a … • Epidemiology and natural history of suicide risk. … • Potential harms of suicide risk interventions. … Risk factors for postpartum depression: an umbrella review.

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