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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-cancer-medications-for-risk-reduction-2002
May 06, 2002 - The relative risk reduction was similar across all age groups and all risk levels. … was concentrated in women ages 50 and older; the relative risks for women younger than age 50 were smaller … for recruitment into the study. 40
Given a constant relative risk reduction across breast cancer risk … and the relative risk by which the baseline risk is multiplied for tamoxifen users. … ‡HR, hazard ratio, the estimate of relative risk at a given time.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/coronary-heart-disease-screening-using-non-traditional-risk-factors-2009
October 15, 2009 - significant
relative risks that ranged from 1.36 to 1.90. … factors in asymptomatic persons (1300 to 16 000 men and women who showed a relative risk of 1.19 to … In summary, although the 8 included studies consistently reported statistically significant relative … risks for coronary events with increasing CAC scores, no study uniformly met all 3 of the following conditions … risk variables (including diabetes), the summary estimate of relative risk for incident CHD was 1.58
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-nsaids/aspirin-nsaids-for-prevention-of-colorectal-cancer-preventive-medication-2007
March 15, 2007 - Confounders Addressed in Adjusted Relative Risks among the Included Case-Control Studies: Use of Nonaspirin … Confounders Addressed in Adjusted Relative Risks among the Included Case-Control Studies: Duration of … We chose relative risk as the effect measure. … Confounders Addressed in Adjusted Relative Risks among the Included Case-Control Studies: Use of Nonaspirin … Confounders Addressed in Adjusted Relative Risks among the Included Case-Control Studies: Duration of
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March 01, 2007 - We chose relative risk as the effect
measure. … We directly abstracted point esti-
mates of the adjusted relative risks and their 95% CIs from
the reports … NSAIDs [54];
1.43 (0.99–2.07) for rofecoxib vs. celecoxib [58]
* Data reported are relative risks (95% … Confounders Addressed in Adjusted Relative Risks among the Included Case–Control Studies: Use of Nonaspirin … Confounders Addressed in Adjusted Relative Risks among the Included Case–Control Studies: Duration of
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/gXnmnkofo8FxoLnCmXJDjb
October 01, 2009 - sig-
nificant relative risks that ranged from 1.36 to 1.90. … fac-
tors in asymptomatic persons (1300 to 16 000 men and
women who showed a relative risk of 1.19 … In summary, although the 8 included studies consis-
tently reported statistically significant relative … risks for cor-
onary events with increasing CAC scores, no study uni-
formly met all 3 of the following … of relative risk for incident
CHD was 1.58 (CI, 1.37 to 1.83) for an hs-CRP level
greater than 3.0 mg
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www.uspreventiveservicestaskforce.org/uspstf/document/final-modeling-study/aspirin-to-prevent-cardiovascular-disease-preventive-medication
April 26, 2022 - In all scenarios, non-CRC benefits and harms were assumed to take effect immediately, and relative risks … estimate was lower and had a narrower confidence interval compared with the corresponding finding in 2016 (relative … for CRC incidence and affects fatal major gastrointestinal bleeding risks. … constant over time, but lifetime net benefits of aspirin would be higher if these relative risks decreased … CVD
Parameter
Relative
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/-hnLT26c2NHs6thK9yznPF
July 01, 2002 - The
relative risk reduction was similar across all age
groups and all risk levels. … was concentrated in women aged 50
and older; the relative risks for women younger than
age 50 were smaller … Considerations of Risk of
Developing Breast Cancer
The relative risk reduction for estrogen receptor … for recruitment into the study.40
Given a constant relative risk reduction across
breast cancer risk … and the relative risk by which the
baseline risk is multiplied for tamoxifen users.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary29/hepatitis-b-virus-infection-screening-nonpregnant-adolescents-adults-may-2014
May 27, 2014 - For antiviral therapy and vaccination, we conducted meta-analyses to calculate relative risks using the … For antiviral therapy and vaccination, we conducted meta-analyses to calculate relative risks using the … There are 2 studies comparing adefovir and placebo, with a pooled relative risk of 2.02 and 95% CI of … Two studies had no incidence of mortality in either group, resulting in relative risks that were not … In the third study, the relative risk was 1.48 with a 95% CI of 0.48 to 4.53.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/aspirin-use-prevent-cardiovascular-disease-colorectal-cancer-preventive-medication-2002
January 15, 2002 - In PHS, aspirin reduced the relative risk for myocardial infarction for patients aged 70 to 84 years … Relative risks were 0.75 for patients aged 50 to 59 years and 0.61 for patients aged 60 to 64 years. … In PHS, patients who were taking aspirin and had SBP greater than 150 mm Hg had a relative risk of 0.65 … for myocardial infarction, compared with relative risks of 0.55 for those with SBP between 130 and 149 … The summary relative risk for hemorrhagic stroke with aspirin use was 1.84 (95 percent CI, 1.24 to 2.74
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/xUc_vXf7323faUQY7SePhT
January 01, 2002 - Age
In PHS, aspirin reduced the relative risk for
myocardial infarction for patients aged 70 to 84
years … Relative risks were 0.75 for patients aged 50 to 59
years and 0.61 for patients aged 60 to 64 years. … In PHS, patients
who were taking aspirin and had SBP greater than
150 mm Hg had a relative risk of 0.65 … for
myocardial infarction, compared with relative risks
of 0.55 for those with SBP between 130 and … The summary relative risk for hemorrhagic
stroke with aspirin use was 1.84 (95% CI, 1.24 to
2.74).
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/3HxQuXnyqHpUKNqjB7hWBw
September 01, 2005 - risks for breast
and ovarian cancer in moderate- and high-risk groups. … All chemoprevention trials reported relative
risk (RR) estimates, and the logarithm of the RR (logRR) … Combining all trials in a meta-analysis resulted in a
relative risk for total breast cancer of 0.62 ( … The relative risk (0.39 [CI, 0.20 to 0.79]) was
further reduced for estrogen receptor–positive breast … Relative risks for breast cancer in chemoprevention
trials.
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June 03, 2019 - below 1 after 16 or more years of
follow-up (relative risk, 0.79). … The
relative risks by year of observation (including trial plus
follow-up time) are shown in the Figure … Both of these trials reported relative risk re-
ductions among women 65 to 74 years of age (relative … (50),
1997
No 5 Swedish trials Weighted relative
risks
12.8 0.77 (0.59–1.01)
Nyström et al.
(32), … Relative risk was calculated as
exp(�).
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-medications-for-risk-reduction-2013
September 15, 2013 - that treatment with tamoxifen or raloxifene can significantly reduce the relative risk (RR) for invasive … Breast Cancer Prevention Trial; IBC = invasive breast cancer; WHI = Women's Health Initiative; RR = relative … Breast Cancer Prevention Trial; IBC = invasive breast cancer; WHI = Women's Health Initiative; RR = relative … Breast Cancer Prevention Trial; IBC = invasive breast cancer; WHI = Women's Health Initiative; RR = relative … Breast Cancer Prevention Trial; IBC = invasive breast cancer; WHI = Women's Health Initiative; RR = relative
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/cTa7Hs56-yj4kCr7yXLdRm
July 01, 1994 - Using the relative risks reported
by Kerlikowske and colleagues (16), we can estimate that
a family … Calculated from relative risk
estimates and ovarian cancer incidence data from the SEER (Surveillance … associated
with contraceptive pill use; both found similar relative
risks of approximately 0.65 associated … ; both
studies found a relative risk of approximately 0.5 after 5
years of use.
3.11 Parity has also … 50% (that is, a
relative risk of 0.5) for any pregnancy, with decreasing
risk associated with an increasing
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-bleeding-risks-with-aspirin-use/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
April 11, 2016 - outcome, we calculated a range of expected event rates after aspirin intervention using the pooled relative … events will vary depending on individual baseline bleeding risks. … why persons with these risks have been excluded from trials. … Level †
Baseline Risk for Outcome,
events per 1000 person-years
Relative Risk (95% CI)
Events … ¶ Using cohort baseline risk and trial relative risks to estimate events caused or prevented.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-cancer-screening-2002
September 03, 2002 - Data Synthesis: For studies of fair quality or better, the summary relative risk was 0.84 (95% CrI, … follow-up (relative risk, 0.79). … The relative risks by year of observation (including trial plus follow-up time) are shown in the Figure … Both of these trials reported relative risk reductions among women 65 to 74 years of age (relative risk … Relative risk was calculated as exp(β).
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/j69Hq5ALvzg74e-ngkzSep
April 01, 2016 - outcome, we calcu-
lated a range of expected event rates after aspirin in-
tervention using the pooled relative … Baseline Estimates of Major Bleeding Risks
(Trial vs. … Risk for Outcome,
events per 1000 person-years
Relative Risk (95% CI) Events Caused per 1000
Person-Years … as reported by included cohort studies.
¶ Using cohort baseline risk and trial relative risks to estimate … why persons with these risks have
been excluded from trials.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/uPbfDukSXmFDWq8FDwTgKj
Clinical Summary: Risk Assessment for Cardiovascular Disease With Nontraditional Risk Factors … Clinical Summary: Risk Assessment for Cardiovascular Disease With Nontraditional Risk Factors
Population … Grade: I (insufficient evidence)
Risk Assessment
Several traditional risk factors are associated … Risk factors can be combined in many w ays to
classify a person's risk for a CVD event. … CVD risk assessment in the United States has been generally based on the Framingham
Risk Score and the
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/4fdC2JLwP_um_yZe4WZRaa
April 01, 2009 - prevention studies of aspirin have found the following:
Clinician Fact Sheet
Aspirin use in women
y 17% relative … relative risk reduction
for MI
y No effect on stroke or
all-cause mortality
y Talk With Your … Harms from aspirin include the risks of serious upper GI bleeding and hemorrhagic
stroke. … this risk in women. … For these individuals,
the benefits and risks of using aspirin are closely balanced.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-and-ovarian-cancer-brca-testing-screening-2005
September 15, 2005 - risks for breast and ovarian cancer in moderate- and high-risk groups. … All chemoprevention trials reported relative risk (RR) estimates, and the logarithm of the RR (logRR) … Sampling Distribution for Relative Risk
When developing the outcomes table, the estimates of relative … Risk
(95% CI)
Type
Treat-
ment
Group, n
Placebo
Group, n
Relative Risk … Relative Risks for Breast Cancer in Chemoprevention Trials