-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bundled-payments-quality-effects_research-protocol.pdf
June 23, 2011 - The evidence of risks (e.g.,
patient selection) will also be summarized. … Analyzing shifts in economic risks to providers in proposed payment
and delivery system reforms. … size that is unlikely
to have occurred in the absence of a
true effect of the intervention (e.g.,
relative … risk >5). … effect size that it
could have occurred solely as a result
of bias from confounding factors (e.g.,
relative
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_disposition-comments.pdf
June 07, 2013 - increased risk?? decreased risk?? … question from this reviewer is whether an
OR was actually calculated for cohort studies or whether
a relative … age-specific incidences (rates) to
probabilities, then, assuming that the odds ratios
were estimates of relative … risks, applied the OR to the
probabilities. … However, it is
interesting to note that the results of relative risk by
duration of oral contraceptive
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-cancer-risk-reduction_research.pdf
October 25, 2010 - of how to communicate
benefits and risks to patients 77.8% 4
How clinicians are weighing
the risks … Individualized risks
2) Education
a. … Studies of how doctors are weighing the
risks and benefits of medications to reduce
breast cancer risk … of how to communicate
benefits and risks to patients 77.8% 4
How clinicians are weighing
the risks … Analysis
of odds ratio of increased relative risk of
developing breast cancer in different groups
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_surveillance.pdf
December 01, 2015 - Relative risk estimates: 0.89 to 1.2. … Women: No difference in relative risk estimates for SVR
•! Blacks vs. … Non-Black patients: No clear difference in relative risk estimates. … Relative risk estimates: 0.89 to
1.2. … Non-Black patients: No
clear difference in relative risk
estimates.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_surveillance.pdf
December 01, 2015 - Relative risk estimates: 0.89 to 1.2. … Women: No difference in relative risk estimates for SVR
•! Blacks vs. … Non-Black patients: No clear difference in relative risk estimates. … Relative risk estimates: 0.89 to
1.2. … Non-Black patients: No
clear difference in relative risk
estimates.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive.pdf
October 01, 2015 - Pooled risks were calculated using a
random-effects model using the method of DerSimonian
and Laird … 2,000 based on an
expected 0.1 probability of CIN in the comparison group
and a minimally important relative … of 10,000 based on an expected
0.02 probability in the comparison group and a minimally
important relative … risk difference of 25 percent. … such
risk factors.
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_10-user-guide-to-ocer_130129.pdf
January 01, 2011 - fixed followup and is rare,
Poisson regression with robust standard errors can
be used to estimate relative … risks and get correct
confidence intervals.8-9 For count data, Poisson
regression can also be used … Otherwise, there are risks with regards
to interpretation of study findings. … Relative risk
regression in medical research: models, contrasts,
estimators, and algorithms. … Adjustment for multiple cardiovascular risk
factors using a summary risk score.
-
effectivehealthcare.ahrq.gov/sites/default/files/s89.pdf
October 01, 2007 - †One-sided test; when relative risk �1, the log likelihood ratio was set to 0. … Cases
in the 42 d After
Meningococcal
Vaccination by Week 106
Relative Risk in
Vaccinated Group
Log … †One-sided test; when relative risk �1, the log likelihood ratio was set to 0. … The dashed line depicts
the relative risk.
TABLE 4. … Cases of
Thrombocytopenia
in the 42 d After
Vaccination
Relative Risk Log Likelihood Ratio*Observed
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_disposition-comments.pdf
August 23, 2013 - bleeding risk, our roundtable experts concluded that
more research is needed into specific risks … stated a
measure of “% reduction” and it’s not clear if this
point estimate (95% CI) is calculated on relative … (95% CIs) are
reported as HRs, however, Connolly et al 2009
reported RE-LY efficacy endpoints as relative … We now clarify that the % reduction was a relative risk reduction. … We have highlighted the risks associated
with use of dabigatran re: risk of MI as well as dyspepsia
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/future05-breastcancer-10-5-2010final.pdf
September 01, 2010 - What is best method to communicate risks?
4) Influences
a. … Individualized risks
2) Education
a. … Studies of how doctors are weighing the
risks and benefits of medications to reduce
breast cancer risk … Analysis
of odds ratio of increased relative risk of
developing breast cancer in different groups … Benefits and
risks of raloxifene by vertebral fracture
status.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gestational-diabetes-screening-diagnosis_disposition-comments.pdf
January 01, 2020 - Long-term risks are not directly related to short
term outcomes. … .adjusted odd ratios
(aORs) of 1.75 relative to the mean cohort glucose values...'
1.75-fold is a relative … gain are
more/equally important for adverse outcomes and clinicians
do not rely on isolated OGTT relative … risks or odd ratios but
on women individual multifactorial absolute risks. … Research indicates
that IGT and GDM carry similar risks of adverse outcomes.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-206-evidence-summary-sodium-potassium.pdf
June 01, 2018 - Effectiveness Review
Number 206
Sodium and Potassium Intake: Effects on
Chronic Disease Outcomes and Risks … CVD, stroke,
congestive heart failure, and kidney disease.16 Lowering
blood pressure lowers these risks … through 2002) and updated
evidence, regarding sodium and potassium intakes, blood
pressure, and the risks … Quality (Risk of Bias) Assessment of Individual
Studies
Risk of bias (RoB) of eligible studies was … Sodium and Potassium
Intake: Effects on Chronic Disease Outcomes and Risks.
-
effectivehealthcare.ahrq.gov/sites/default/files/considerations-for-statistical-chapter-10.pptx
January 01, 2013 - fixed followup and is rare, Poisson regression with robust standard errors can be used to estimate relative … risks and get correct confidence intervals. … UW Biostatistics Working Paper Series: Relative risk regression in medical research: models, contrasts … Disease Risk Scores
Disease Risk Scores
The disease risk score (DRS) is an alternative approach to … The DRS is useful for summarizing disease risk and assessing effect modification by disease risk.
-
effectivehealthcare.ahrq.gov/sites/default/files/bar-cohen_-eccs2012.pdf
January 01, 2012 - Health
Education
and
Decision Making
(3 of 4)
Questions to ask
when
interpreting
risks … and benefits
• Risk of what? … • How big
is the change in
risk?
… • How does this risk compare to other risks? … • What
would give patients a better idea
of the risks involved in
breast
cancer?
-
effectivehealthcare.ahrq.gov/sites/default/files/communicating_risk_media_wilkes.ppt
April 01, 2006 - , small differences between risks, and uncertainty around risks
Public Expectations
Public believes … million cases of breast cancer.
raloxifene is already used to prevent bone loss after menopause
NCI used relative … risk reductions in their promotion rather than absolute risk reductions
At the press release and conference … Why are risks minimized? … new possibilities
Tools to help patients better understand the health care system and risk
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-273-anal-cancer-executive-summary.pdf
August 01, 2024 - We evaluated risk of bias (RoB) using the
Cochrane RoB2 tool for RCTs and the ROBINS-I tool for NRSIs … • Most of the studies are assessed with high risk of bias. … GI-gastrointestinal; GU-genitourinary; RCT- randomized controlled trial; yrs- years; vs.- versus;
RR- relative … measurement
between trials, inadequately addressing attrition, multiple comparisons testing, and
competing risks … interventions and comparators, lack of power calculations, and inadequately addressing
missing data, competing risks
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
February 01, 2013 - diagnostic information produced
actually translates into benefits for patients that outweigh
the risks … of MI in the FFR group (relative risk
[RR]: 0.62, 95% confidence interval [CI]: 0.40 to 0.95). … of
Relative Risk†
(95% CI)
All-cause
mortality
In-hospital 3 (925) No events (3 RCTs) 2 (1,802) … †A relative risk <1 indicates a favorable effect with IVUS use. … †A relative risk <1 indicates a favorable effect with IVUS use.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-264-maternal-morbidity-mortality-executive-summary.pdf
December 01, 2023 - factors, including biological/medical risk
factors … • Limited depth and quality of available research within each risk factor domain—
including racism … • Rarely did studies report the excess risk attributable to a specific exposure. … Our focus
was studies that attempted to examine pathways underlying risks. … We purposefully focused on studies that
examined risk factors that operated interpersonally.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_executive.pdf
April 01, 2013 - KQ 4: For adults exposed to psychological trauma,
what are the absolute and comparative risks of harms … For
binary outcomes (e.g., incidence of PTSD), we calculated
the relative risk (RR) between groups. … ; n = subset of sample; PE = prolonged exposure therapy; PTSD = posttraumatic stress disorder; RR = relative … of Harms
Little evidence exists addressing either the general or
the comparative risks of harms from … Evidence addressing the absolute risks or comparative
risks of harms from early interventions intended
-
effectivehealthcare.ahrq.gov/sites/default/files/s158.pdf
October 01, 2007 - Generaliza-
tion from trials can be erroneous because effect sizes, base-
line risks, and comorbidity … Without adjustment for smoking, the relative risk of lung
cancer in those exposed to diesel exhaust was … This multiple im-
putation led to an estimate of the relative risk for lung cancer
and exposure to diesel … Because the relative risk
for vasectomy and myocardial infarction was essentially the
same before and … Correction of logistic regression
relative risk estimates and confidence intervals for measurement error