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Total Results: 2,111 records

Showing results for "risk".

441. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_executive.pdf
     December 01, 2011 - potentially cuts both ways as strains drift toward lesser or higher virulence, and the possible future risks … toxin clearance for vancomycin.77,80 Harms were not reported with sufficient detail to compare the risks … Such studies generally exclude high-risk patients. … general, increased risk of CDI … Risk factors for Clostridium difficile toxin-associated diarrhea.

442. Disposition of Comments Report for Core Needle and Open Surgical Biopsy for Diagnosis of Breast Lesions: An Update to the 2009 Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_disposition-comments.pdf
     September 10, 2014 - Also, in Table C, it is not clear whether “high risk” refers to high risk women, or a high risk lesion … Because over-diagnosis is the end result of lead time (due to screening) and competing risks (specifically … Because over-diagnosis is the end result of lead time (due to screening) and competing risks (specifically … , regardless of patient risk. … to assess risk of bias.

443. Chronic-urinary-retention-protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-urinary-retention_research-protocol.pdf
     November 19, 2012 - Assessment of Methodological Risk of Bias of Individual Studies. … Risk of bias of eligible studies will be assessed using instruments specific to study design. … Investigators will consult to reconcile any discrepancies in overall risk of bias assessments. … Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S, eds. … Development of the RTI item bank on risk of bias and precision of observational studies.

444. Contrast-Induced Nephropathy (CIN): Current State of the Evidence on Contrast Media and Prevention of CIN (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_clinician.pdf
     August 01, 2016 - and Prevention of CIN e Conclusions The reviewed studies provided the following evidence: �� The risk … between the various types of LOCM (low strength of evidence [SOE]). �� The IOCM has a slightly lower risk … The lower risk was statistically significant but unlikely to be clinically important. �� The risk of … b Clinically important effect was defined by a risk ratio less than 0.75 or greater than 1.25. … b Clinically important effect was defined by a risk ratio less than 0.75 or greater than 1.25. ⬇ =

445. Dementia-Agitation-Aggression Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-agitation-aggression_research-protocol.pdf
     November 13, 2014 - including mortality22-24 and their use is associated with reduced quality of life.25 The risks associated … We will reassess risk of bias of included studies for comparison purposes. … Assessment of Methodological Risk of Bias of Individual Studies Risk of bias of eligible studies will … We will calculate risk ratios (RR) and absolute risk differences (RD) with the corresponding 95 percent … Chapter 8: Assessing risk of bias in included studies.

446. Fecal-Incontinence Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_research-protocol.pdf
     November 30, 2014 - Assessment of Methodological Risk of Bias of Individual Studies The risk of bias of eligible studies … For RCTs, we will assess the risk of bias using a modified Cochrane Risk of Bias tool.37 The seven domains … Similar to risk of bias for RCTs, the overall summary risk of bias will be weighted lower for studies … across risk of bias approaches. … If the risk of bias assessment tool is similar to our approach, we will separately assess risk of bias

447. Identification and Treatment of Post-Acute Coronary Syndrome (ACS) Depression: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
     February 15, 2017 - usually effective in the general population are less so among post-ACS patients, or carry certain risks … , or risk of bias, for each individual study based on the Cochrane Risk of Bias tool for randomized … Other risks: akathisia, restlessness, sedation, headache, nausea and vomiting Olanzapine6 For bipolar … Quetiapine7 Yes, as an adjunct with an antidepressant Other risks: sedation, hypertension, cataracts … Other risks related to tricyclic antidepressants include altered cardiac conduction (prolonged QTc),

448. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND__0250_05-20-2010.pdf
     January 01, 2010 - intervention, harm(s) of intervention, maintenance of sinus rhythm, mortality, accuracy and utility of risk … Prevention of Atrial Fibrillation and Progression to Heart Failure Population(s): Adults with, or at high risk … What are the accuracy and utility of methods of risk stratification to guide choice of therapy (e.g. … The evolution of newer anticoagulation agents as well as the risks and benefits when compared to older

449. Prostate-Cancer-Test Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-test_executive.pdf
     April 01, 2013 - of being diagnosed with prostate cancer is 16 percent, but lifetime risk of dying from the disease … about biopsy, risk classification, and/or treatment options. … , risk factors, biochemical markers, and clinical/pathological staging. … or high-risk disease. … Predicting prostate cancer risk through incorporation of prostate cancer gene 3.

450. Disposition of Comments Report for Recurrent Nephrolithiasis in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stone-prevention_disposition-comments.pdf
     July 26, 2012 - These were rare events without sufficient evidence to suggest that risk of death was associated with … Epidemiological data suggest that low calcium diets increase risk of kidney stones, and differences … Other biological processes besides urine chemistries may contribute to risk of recurrent stones. … Of note, we identified no trials limited to patients with these kidney stone risk factors or that … The authors should recognize that kidney stone risks are continuous and that such categorization is

451. Disposition of Comments for CER 176 Management of Gout (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout-management-disposition-160721.pdf
     March 15, 2016 - of chronic gout (e.g., taking a long term medication to lower serum urate, with the concomitant risks … We are not saying that the benefits exceeding the risks of such a strategy is not a plausible outcome … accompanied by metabolic syndrome and in addition to adverse effects noted, there are significant risks … Any evidence on the magnitude of these risks and whether urate lowering changes them? … Essentially, the current report risks boxing in primary care providers to inferior quality of care for

452. Disposition of Comments Report for Evaluation and Treatment of Cryptorchidism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_disposition-comments.pdf
     December 11, 2012 - Peer Reviewer #6 Introduction Page 29, Line 54: Page 1--next to last line, the reference that the relative … Peer Reviewer #7 Introduction Page 29, Line 54: "relative risk of testis CA after UDT is 40X gen population … I think a more complete discussion of malignancy risks should be included and would fit under KQ 4, … population most likely will require sedation or anesthesia, which has the potential for significant risks … Pettersson et al- NEJM- risk of testis ca with UDT P.

453. Glasgow Coma Scale for Field Triage of Trauma: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/field-triage-glascow_executive.pdf
     January 01, 2017 - is needed to understand how use of the tGCS versus the mGCS or SMS impacts clinical outcomes and risk … The ultimate goal of selecting one risk prediction instrument over another is to improve clinical … , and predictive values), or adjusted risk estimates (e.g., odds ratio, relative risk, hazards ratio … ).21 Other factors that could inform selection of field triage risk assessment instruments include … adults or mixed), study year (before 2006 or 2006 or later), or risk of bias ratings.

454. Peripheral-Artery-Disease-Treatment Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/peripheral-artery-disease-treatment_research-protocol.pdf
     January 31, 2013 - infarction, stroke, or cardiovascular death), such that as the ABI decreases, the risk of ischemic … of future cardiovascular morbidity and mortality in patients with high ischemic risk. … The duration of treatment and followup will be considered when evaluating the benefits and risks of … included; the duration of treatment and followup will be considered when evaluating the benefits and risks … Risk factors for atherosclerotic cardiovascular outcomes in different arterial territories.

455. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/progestogens-preterm-birth_research-protocol.pdf
     June 01, 2010 - critical gaps in our knowledge, particularly with regard to identifying and treating women at high risk … If all at-risk pregnant women were treated with 17-OHP, the aggregate medical cost savings could be … could be more than $2 billion.10 The ultimate goal in preventing preterm birth is to eliminate the risks … In general, the figure illustrates how the use of progestogens in women at risk for preterm birth may … A woman’s risk of preterm birth is determined by risk factors such as http://www.effectivehealthcare.ahrq.gov

456. Trauma-Interventions-Maltreatment-Child Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-interventions-maltreatment-child_executive.pdf
     April 01, 2013 - Although children at risk and children with known maltreatment exposure can present similar risk and … Studies with a medium risk of bias are those that do not meet all criteria required for low risk of … that we rated high risk of bias. … interval; G = group; NR = not reported; OR = odds ratio; PCIT = Parent-Child Interaction Therapy; RRR = relative … Because these population characteristics represent baseline risks that are prevalent in the target

457. Asthma-Immunotherapy-2011 Research (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2011_research.pdf
     January 01, 2011 - association between risk factors and disease outcomes. … ” and for risk assessment guidance. … D Included association with risk factors in gender subgroups E Included association with risk … Define risk factor or list risk factors for which quality assessment would be the same. … Define risk factor or list risk factors for which quality assessment would be the same: Source to

458. Disposition of Comments Report for Treatment for Hepatitis C Virus Infection in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_disposition-comments.pdf
     November 27, 2012 - diagnosed, and patients who are diagnosed late or not at all face substantial morbidity and mortality – risks … interferon alfa-2a vs. dual therapy with pegylated interferon alfa-2b, and found no difference in the relative … Results (p.43) Triple therapy with Telaprevir was associated with increased risk of anemia. … diagnosed, and patients who are diagnosed late or not at all face substantial morbidity and mortality – risks … Risk factors for the rising rates of primary liver cancer in the United States.

459. Clopidogrel after Drug-Eluting Stent Implantation: Is current practice sufficient (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stent-clopidogrel-practice_research.pdf
     March 01, 2009 - The extended use of clopidogrel in drug-eluting stent patients may be associated with a reduced risk … key parameters for subsequent research in this area. 25 Extended clopidogrel therapy has its own risks … Estimation of Cumulative Incidence in the Presence of Competing Risks. … at 12 months Death MI* Death/ MI # at risk at 24 months DES+C† 252 0 0 0 230 DES-C … DES-C comparison is 0.020 DES+C DES-C BMS-C BMS+C Number at Risk DES+C 600

460. Management of Uterine Fibroids - Evidence Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-195-uterine-fibroids-final.pdf
     December 01, 2017 - in the first year of diagnosis.8,9 Purpose of Review To review treatment effectiveness and the risk … . 2 Treatment options differ in fundamental aspects such as cost, invasiveness, recovery time, risks … Unfortunately, the published literature does not contain enough detail to stratify risks by age, menopausal … from those with lower risk. … Risk factors for surgically removed fibroids in a large cohort of teachers.