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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0319_06-17-2009.pdf
January 01, 2009 - whether these serum biomarkers
provide evidence for the diagnosis or prognosis of sepsis for patients at risk … For patients at risk for, or in, sepsis, are there serum biomarkers available for the
diagnosis and … For patients at risk for, or in, sepsis, does C reactive protein provide any utility in
their management … For patients at risk for, or in, sepsis, does procalcitonin provide any utility in their
Sepsis Biomarkers … For patients at risk for, or in, sepsis, does cortisol provide any utility in their
management?
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-screening_research-protocol.pdf
October 20, 2011 - evaluated the effectiveness of treatment for HCV infection within the context of screening and
risk … Does becoming aware of positive HCV infection status decrease high-risk behaviors?
c. … High-risk sexual behaviors
c. … Screening of the general population versus “targeted” high-risk groups (KQ 2)
3. … Assessment of Methodological Risk of Bias of Individual Studies
We will assess the risk of bias
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/worker-health_research-protocol.pdf
May 26, 2015 - mortality, morbidity, and
considerable financial and social costs.1-3 At the same time, modifiable risk … Community Preventive Services Task
Force recommends worksite interventions (assessments of health risks … A study with moderate risk of bias is susceptible to some risk of bias but
probably not enough to invalidate … A study assessed as high risk of bias has
significant risk of bias (e.g., stemming from serious issues … Two independent reviewers will assess risk of bias for each study.
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
September 01, 2022 - Tools to assess the risk of bias in NRSIs are
different from those used to assess risk of bias in RCTs … after mastectomy,18 have included single-group
studies for (noncomparative) quantification of the risks … Assessing the Risk of Bias in NRSIs
Existing instruments for assessing the risk of bias in NRSIs89, … This methodological heterogeneity can be due to many factors, including differences in risks of
selection … Assessing risk of bias in a randomized
trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
September 01, 2022 - Tools to assess the risk of bias in NRSIs are
different from those used to assess risk of bias in RCTs … after mastectomy,18 have included single-group
studies for (noncomparative) quantification of the risks … Assessing the Risk of Bias in NRSIs
Existing instruments for assessing the risk of bias in NRSIs89, … This methodological heterogeneity can be due to many factors, including differences in risks of
selection … Assessing risk of bias in a randomized
trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_consumer.pdf
January 01, 2017 - What increases the risk of gout?
The exact cause of gout is not known. … But, certain things may
increase the risk of getting it. … Being overweight can also
increase the risk of gout. … � Allopurinol (Zyloprim®) and febuxostat (Uloric®) do not lower the
risk of a gout attack in the … In fact, these medicines can increase the risk of a gout attack when you first start
to take them.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
November 01, 2013 - Individual Study-
Level Risk of Bias
Assessments
2. … Combining evidence from studies with a high risk of bias and those with less risk can be
problematic … of
bias versus high risk of bias. … Selection in reported epidemiological risks:
an empirical assessment. … Framework for examining risk of reporting bias
Abbreviations: N = number; RRB = risk of reporting
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mrsa-screening-2010_executive.pdf
January 01, 2010 - SOE was lowered by the high risk
of bias. … SOE was lowered by
the high risk of bias. … SOE was
lowered by the high risk of bias. … SOE was lowered by
the high risk of bias. … attempt to measure the favorable
impact of screening for MRSA carriage while ignoring
its potential risks
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/emt-naloxon_research-protocol.pdf
November 29, 2016 - With administration using a preloaded
IN system, there is no risk of needle stick injury. … of bias,” “medium
risk of bias,” or “high risk of bias.” … Studies rated “low risk of bias” are considered to have the least risk of bias, and their
results are … We will not exclude studies rated high risk of bias a priori, but high
risk of bias studies will be … Risk Factors of Prescription Opioid
Overdose Among Colorado Medicaid Beneficiaries.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy_executive.pdf
January 01, 2017 - We considered 67 studies to have low risk of bias,
110 to have moderate risk, and 41 to have high risk … cohort studies had high risk. … Eighteen
studies had low risk of bias, 28 had moderate risk, and
13 had high risk. … Twenty-two studies had
low risk of bias; 36 had moderate risk; and 12 had high
risk. … balance
needs for relief of illness-related outcomes (including
missing school and work) with the risks
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-future_research.pdf
April 01, 2013 - Relative risk estimates ranged from 1.0 to 1.3 in the four
trials and may have varied in part due to … Relative risk estimates ranged from 0.89 to 1.1.
5
Table 1. … risk estimates for SVR in men vs. … women, and no clear difference in relative risk estimates for
Black vs. non-Black patients. … for risk of
harms that were similar to the risk estimates based on all
trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-knee-physical-therapy_research-protocol.pdf
April 01, 2010 - hypotheses and did not provide adequate
information on tested hypotheses (e.g., least square means, relative … risk).
8. … risk, and absolute risk differences. … For observational studies we will extract relative measures of the association
(relative risk, hazard … We will calculate differences in relative risk and absolute risk from the abstracted events by
using
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/fibromyalgia_research-protocol.pdf
April 03, 2014 - For randomized clinical trials (RCTs), we will assess the risk of bias using a modified
Cochrane Risk … Similar to risk of bias for RCTs, the overall summary risk of bias will
be weighted towards low for … Risk of bias of pooled analyses
will depend in part on the risk of bias of the inputs (RCTs) and the … risk of bias in how the pooled
analysis was conducted and reported. … good studies (low risk of bias) for high strength of evidence.
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_2-user-guide-to-ocer_130129.pdf
January 01, 2011 - Incidence is generally
assessed as a risk/proportion over a fixed
time period (e.g., risk for 1-year … estimation of risk or rate
differences. … Controls were
only sampled from the “risk set.” … The cohort
design has the added advantage that absolute risks
or incidence rates can be estimated and … Statin
adherence and risk of accidents: a cautionary tale.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_surveillance.pdf
December 01, 2012 - of proximal and distal
DVT (relative risk reduction [RRR] 47 percent and
41 percent, respectively) … mechanical prophylaxis
(intermittent pneumatic compression and venous
foot pump) versus control, the risks … For example, if relative risk reduction (RRR) new / RRR old <=0.5 or RRR new / RRR old
>=1.5. … of proximal and distal DVT (relative
risk reduction [RRR] 47 percent and 41 percent, respectively), … mechanical
prophylaxis (intermittent pneumatic compression and venous foot pump) versus control,
the risks
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-decision-support-tools_disposition-comments.pdf
December 23, 2014 - There is a world behind this (risk
communication science, framing risks in various ways (Gigerenzer, … , high risk, early cancer)
and additional intervention characteristics. … their average baseline risk.” … Change to : “accuracy of perception of
mortality risks . . .” … risk
probabilities but 22 studies were for prostate cancer.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/field-triage-glascow_research-protocol.pdf
February 25, 2016 - not address important issues specific to risk prediction studies. … correlates with actual risk), and risk reclassification
rates (the proportion of patients correctly … reclassified using the risk prediction instrument
into clinically relevant risk group), in addition … Two investigators will independently assess risk of bias for each study. … Studies rated “low” risk of bias have the least risk of bias, and their results are
generally considered
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0086_04-01-2009.pdf
January 01, 2009 - Description
Nominator: Individual
Nomination
Summary:
The nominator is interested in the risks … For the elderly taking cardiovascular medications, what are the comparative risks
and benefits of commonly
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_clinician.pdf
July 01, 2017 - .
�� Percutaneous renal mass sampling using core biopsy is a
low-risk procedure. … were observed:
�– Increased tumor size and male sex were consistently
associated with an increased risk … As such, younger patients and those
with other comorbidities may have differing risks of
malignancy … may wish
to discuss with patients whether a biopsy is warranted and
what the potential benefits and risks … Strategies for Oncologic Outcomes and Overall Survival
Outcome
No. of
Studies (N) Key Findings Risk
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth-disposition-121205.pdf
September 07, 2012 - Combs paper and the
general need for larger datasets to assess
harms such as IUFD and neonatal death risks … Results Page 53 of 518, the statement is made that “the meta-estimate
combining these three trials is a relative … risk of 0.44 (95 percent
CI: 0.26, 0.76)”. … I think the data indicating
differential efficacy with different risks for preterm birth is
sufficient … to allow the authors to make the statement that in
future analyses, different risks would need to be