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Total Results: 2,117 records

Showing results for "risk".

401. Accelerated Partial Breast Irradiation: Executive summary for the update of an ASTRO Evidence-Based Consensus Statement (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-nomination-apbi-breast-cancer.pdf
     April 01, 2017 - define a group of patients with low-risk DCIS for whom observation confers a low absolute risk of IBTR … of IBTR.17 When analyzed by the ECOG 5194 risk criteria, the risk was 2% for patients meeting these … low-risk criteria. … However, given the low risk of IBTR in low-risk DCIS with wide local excision alone, coupled with favorable … results following APBI for low-risk DCIS in several series, the task force recommends inclusion of low-risk

402. Technical Brief 13: Gene Expression Profiling for Predicting Outcomes in Stage II Colon Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_technical-brief.pdf
     December 01, 2012 - Identifying the individuals in whom the potential benefits of chemotherapy outweigh the risks is challenging … On the other hand, introducing routine testing without a clear understanding of benefits and risks could … obtained with standard risk factors? … The discussion with a patient about the benefits and risks of adjuvant chemotherapy usually occurs 3 … use of the GEP assay for treatment management improve net health outcome (considering benefits and risks

403. Methods-Guidance-Reporting-Bias Methods (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-reporting-bias_methods.pdf
     November 01, 2013 - Agency found that while published data indicated that benefits of the study drugs outweighed their risks … , that the inclusion of unpublished data suggested that risks outweighed benefits for all but one of … additional data (11 studies; 996 patients) 18 changed results from statistically significant (RR [relative … for reporting bias for this outcome (“ORB risk–” or “ARB risk–”). … the results were reported, then the study is at risk of reporting bias for that outcome (“ORB risk

404. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/tympanostomy-tubes_research-protocol.pdf
     November 16, 2015 - There is interest in comparative effectiveness of tympanostomy tubes in high-risk and at-risk populations … Many randomized trials are relatively small, limiting their ability to define risks of less common harms … For RCTs, we will use the Cochrane risk of bias tool 22, which asks about risk of selection bias, performance … Tympanostomy tube outcomes in children at-risk and not at-risk for developmental delays. … Panel 1: Epidemiology, natural history, and risk factors.

405. Transparency of Reporting Requirements: Omega-3 Fatty Acids and Cardiovascular Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-omega-3_research-protocol.pdf
     September 02, 2016 - IF HIGH RISK OF BIAS, EXPLAIN IN NOTES. … IF HIGH RISK OF BIAS, EXPLAIN IN NOTES. … IF HIGH RISK OF BIAS, EXPLAIN IN NOTES. … , DM) ** Including diet but not CVD risk factors ** Including CVD risk factors, but not diet ** Neither … IF HIGH RISK OF BIAS, EXPLAIN IN NOTES.

406. Smoking-Pregnancy-Infants Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_executive.pdf
     February 01, 2014 - , and placenta previa.7-10 Health risks to the fetus include low birth weight, restricted growth, … Administration places the transdermal nicotine patch in pregnancy category D, which indicates there are known risks … to the fetus, but potential benefits may outweigh risks in some cases. … adverse fetal effects and no adequate human studies are available, but potential benefits may outweigh risks … Prenatal smoking and risk of intrapartum stillbirth.

407. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
     January 01, 2007 - addition, clinicians must consider concerns about specific medications conferring excess cardiovascular risks … (absolute risk difference of ~2 percent). … The absolute risk difference between groups was ~2%. … The absolute risk differences were ~8-14%. … The between-group absolute risk differences were ~ 5-15%.

408. Amended Protocol: Improving Rural Health Through Telehealth-Guided Provider-to-Provider Communication (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rural-telehealth-amended-protocol.pdf
     February 25, 2021 - of bias,” “medium risk of bias,” or “high risk of bias.” … Studies rated “low risk of bias” are considered to have the least risk of bias, and their results are … We will not exclude studies rated high risk of bias a priori, but high risk of bias studies will be … /rural-communities.html#why-higher-risk 12 precautions/other-at-risk-populations/rural-communities.html … #why-higher-risk.

409. Ptsd-Adults-Trauma-Interventions Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adults-trauma-interventions_research-protocol.pdf
     November 08, 2012 - KQ 4: For adults exposed to psychological trauma, what are the absolute risks or comparative risks of … groups, and sex) o Populations with psychiatric comorbidities o Populations with different personal risks … KQ 4 addresses the absolute and comparative risks of harms and adverse events from these interventions … The “Population at risk…” box was revised as follows: “Population at risk: Adults exposed to psychological … The “Population at risk…” box was revised as follows: “Population at risk: Adults exposed to psychological

410. Omega-3 Fatty Acids and Cardiovascular Disease: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/fatty-acids-cardiovascular-disease_clinician.pdf
     July 01, 2017 - conducted to evaluate the effect of omega-3 fatty acids (FAs) on cardiovascular disease (CVD), its risk … , there is high strength of evidence (SOE) from RCTs that marine oil supplements do not affect the risk … Marine oil supplements also have no effect on the risk of atrial fibrillation (moderate SOE). … �) and no effect on atrial fibrillation (���) in populations with established CVD or at increased risk … of HDL-c and LDL-c (���) in healthy populations and in those with established CVD or at increased risk

411. Methods Guide for Medical Test Reviews Chapter 7 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-grading_methods.pdf
     July 01, 2012 - When the treatment of a disease has high associated risks, multiple tests are often used to assure the … false negatives depends on the severity of disease if there is a missed diagnosis, in addition to the risks … from the testing itself (i.e., if the test is invasive and associated with risks in and of itself). … of bias: • Low risk of bias • Medium risk of bias • High risk of bias Well designed and executed … Assessing risk of bias as a domain of quality in medical test studies.

412. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/angina-heart-attack-treatments_research-protocol.pdf
     December 11, 2012 - • In patients with an indication for oral anticoagulant therapy, what are the risks and benefits of … • In patients receiving dual antiplatelet therapy, what are the risks and benefits of adding a PPI? … The duration of treatment and followup will be considered when evaluating the benefits and risks for … Heart failure • Previous stroke • Renal insufficiency • Type of stent • Type of vascular access Bi Risks … review; the duration of treatment and followup will be considered when evaluating the benefits and risks

413. Renal-Cancer Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_research-protocol.pdf
     April 20, 2015 - renal mass (oncologic outcomes, renal functional outcomes, complications) as well as competing health risks … Assessment of Methodological Risk of Bias of Individual Studies: The assessment of risk of bias of … Risk of bias judgment Overall bias Risk of bias judgment Table 4. … Risk: Low/High/Unclear Archived: This report is greater than 3 years old. … of bias: • Low risk of bias • Medium risk of bias • High risk of bias Well designed and executed

414. Disposition of Comments Report for Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
     September 25, 2013 - Including data available only in abstract form has inherent risks such as numerical errors and misinterpretation … Section Comment Response Peer Reviewers 2, 3, 4 Methods Despite imprecision, the lower bound of the relative … reduction versus increased bleeding risk. … The authors should include a summary of the comparative risks of genetic vs. nongenetic factors routinely … Additionally, it would be appropriate to frame the relative risks between CYP2C19 genotypes against

415. breast-biopsy-update-130920 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_research-protocol.pdf
     September 20, 2013 - a lesion will be classified as benign or as high risk (e.g., atypical ductal hyperplasia [ADH]) or … Assessment of Methodological Risk of Bias of Individual Studies We will assess the risk of bias for … We discuss the handling of high risk of bias studies in sections E and F below. … levels of risk of bias will lead to downgrading the strength of the evidence. … of cancer (women at “average risk” vs. those at “high risk” may affect estimated test performance because

416. Microsoft Word - cognitive-decline-protocol-160322.docx (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cognitive-decline_research-protocol.pdf
     March 22, 2016 - Nonmodifiable risk factors include age, sex, race/ethnicity, and family history. … factor status �Number of risk factors III. … Extraction of basic study information will inform risk of bias assessment. … Assessment of Methodological Risk of Bias of Individual Studies Risk of bias of eligible studies will … We will calculate risk ratios and absolute risk differences with the corresponding 95 percent confidence

417. Total Worker Health® (TWH) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/worker-health_executive.pdf
     April 01, 2016 - Risk-of-Bias Assessment To assess the risk of bias (internal validity) of studies eligible for KQ 2, … A study assessed as high risk of bias has significant risk of bias (e.g., stemming from serious errors … We rated 5 RCTs as medium risk of bias27,28,46,49,50 and the other 10 studies as high risk of bias … interventions included comprehensive program content that highlighted the potential additive or synergistic risks … and included comprehensive program content that highlighted the potential additive or synergistic risks

418. GRADING THE STRENGTH OF A BODY OF EVIDENCE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-strength_methods.pdf
     July 01, 2009 - Risk of Bias As noted in Table 1, the risk of bias for an evidence base will be derived from assessment … of the risk of bias in individual studies. … Risk of bias incorporates both study design and study conduct. … High risk of bias lowers the strength-of-evidence grade; low risk of bias raises it. … of bias: • Low risk of bias • Medium risk of bias • High risk of bias Consistency The principal

419. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0319_06-17-2009.pdf
     January 01, 2009 - whether these serum biomarkers provide evidence for the diagnosis or prognosis of sepsis for patients at risk … For patients at risk for, or in, sepsis, are there serum biomarkers available for the diagnosis and … For patients at risk for, or in, sepsis, does C reactive protein provide any utility in their management … For patients at risk for, or in, sepsis, does procalcitonin provide any utility in their Sepsis Biomarkers … For patients at risk for, or in, sepsis, does cortisol provide any utility in their management?

420. Grading_didactic_faculty_approved (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/grading.ppt
     January 01, 2013 - grade Four Required Domains: Risk of Bias The risk of bias for an evidence base is derived from assessing … Risk-of-bias scores are denoted as high, medium, or low. … High risk of bias lowers the strength-of-evidence grade; low risk of bias raises the strength-of-evidence … DOI: 10.1016/j.jclinepi.2009.03.009 Guiding Principles: Risk of Bias Risk of bias (given design … Guiding Principles: Risk of Bias The risk of bias based on the design and conduct of the available studies