-
effectivehealthcare.ahrq.gov/sites/default/files/ch_11-user-guide-to-ocer_130129.pdf
January 03, 2012 - asked in a study, as
excluding prevalent users might omit long-term
users (which could overlook risks … of
death among the patients treated with aprotinin
(estimates ranged from a relative risk of 1.32 … Sensitivity Analysis
[propensity score] to a relative risk of 1.64
[traditional regression analysis … quickly calcification progresses once the process
has begun.20
First, a model is developed for the relative … 11.2 plots the combination of the odds ratio
between the exposure and the confounder (OREC)
and the relative
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-240-acute-pain-evidence-summary.pdf
December 01, 2020 - • Opioids are probably associated with increased risk of short-term adverse events
versus nonopioid … Evidence did not suggest an
increased risk of serious harms for any intervention, though studies were … Serious adverse events were uncommon, but studies were not designed to
assess risk of overdose, opioid … Being prescribed
3
opioids might be associated with increased risk of long-term use versus … Legislation mandating the use of prescription drug
monitoring data and an opioid risk assessment tool
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_overview.pdf
January 17, 2014 - a number of potential adverse
events associated with rosiglitazone (e.g. increased cardiovascular risks … ), pioglitazone (e.g. increased
risk of bladder cancer), the combination of pioglitazone with insulin … (e.g. cardiac failure), and GLP-1
analogs or DPP-4 inhibitors (e.g. increased risk of pancreatitis)
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_executive.pdf
April 01, 2012 - heart
failure or other cardiovascular disease use dietary
supplementation and are thus placed at risk … of bias for the study as low, moderate, or high risk, and a
second reviewer independently verified … Relative risk (RR) and post-treatment
mean differences (MDs) were meta-analyzed using the
DerSimonian … international normalized ratio; LDL-C = low-density lipoprotein-cholesterol; MD = mean difference; RR = relative … They recruited healthy
subjects, or subjects with CHD or risk factors for CHD.
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia-agitation-aggression_executive.pdf
March 01, 2016 - aggression involves at least one other person
(the target of the aggression) and can represent real risks … handling
of incomplete data); reporting bias (selective reporting
of outcomes or analyses); and other risks … to reduce the use of antipsychotic medications in
people with dementia should continue, given the risks … Evidence about the risks associated with antipsychotic
use in older adults is mounting. … Development of the risk
appraisal measure: a brief screen to identify risk areas and guide
interventions
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_disposition-comments.pdf
June 12, 2012 - other tweaks from invasive
cardiologists, but from my "doc in a box" vantage point of benefits and
risks … According to the Joint Commission’s latest Sentinel Alert, the risks
associated with the use of ionizing … Feinstein, Steven
(International
Contrast Ultrasound
Society)
General 1 Radiation Risks of Diagnostic … We have added more details about the
radiation risk to the Safety Concerns and Risks
section. … The review
includes 11 studies reporting safety concerns and risks, including three
studies that show
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/impact-healthcare-algorithms-racial-ethnic-disparities-March-2.pdf
May 15, 2023 - algorithm scoreRe
al
iz
ed
h
ea
lth
(a
ct
iv
e
ch
ro
ni
c
co
nd
iti
on
s)
Algorithm risk … total
health costs well for
Black and White patients
Re
al
iz
ed
c
os
t (
TM
E)
Algorithm risk … Risk of bias (ROB) The likelihood that a study’s reported results are misleading due to methodologic … Care
Management
1
[Obermeyer 2019]
Commercial risk prediction
calculator
None N Eligibility for … Index KQ 2 Shores 201386 Modellingd * *
Cardiovascular risk
ASCVDc KQ 2 Weale 202173 Modellingd
-
effectivehealthcare.ahrq.gov/sites/default/files/s116.pdf
October 01, 2007 - This model
yielded adjusted estimates of risk differences. … using more hazardous treatments,
the bias would be conservative, tending to narrow the differ-
ence in risks … †Prevalence of risk factor among atypical users minus prevalence of risk factor among conventional users … Risk of death in elderly users
of conventional vs. atypical antipsychotic medications. … Benzodiazepines of long and short
elimination half-life and the risk of hip fracture.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/partial-breast-irradiation-disposition-comments.pdf
January 31, 2023 - Can risks/benefits be used
instead? … Risk/benefit
terminology may
imply that we did
some sort of risk
benefit analysis. … The findings were
generated from
subgroup
analyses and
suffer higher risk
of bias. … of recurrence (with all the caveats of risk & benefit & patient preference discussed). … agree with the AHRQ
review that there is currently insufficient data to draw conclusions about the risks
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disorders-protocol-amendment.pdf
March 22, 2023 - assess risk of bias of included studies. … Each study will
be dual reviewed for risk of bias by two team members. … points on a 0 to 100-point scale
• SMD >0.8
• RR/OR ≥2.0
MD = mean difference; OR = odds ratio; RR = relative … The social ecology of community and neighborhood and risk for antisocial
behavior. … Assessing the Risk of Bias in Systematic
Reviews of Health Care Interventions.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-bias_methods.pdf
July 01, 2012 - Methods Guide for Medical Test Reviews
5-1
Chapter 5
Assessing Risk of Bias as a Domain of Quality … Risk: Low/High/Unclear
*Questions related to assessing applicability were excluded here. … Summarizing risk of bias based on several outcomes within a study is not recommended. … Systematic review: family history in risk
assessment for common diseases. … Assessing risk of bias as a domain
of quality in medical test studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_consumer.pdf
May 01, 2011 - People with broken hips may be at risk for other
problems, such as pneumonia, blood clots, and muscle … There is very little known about
the benefits and risks of traction, acupressure, muscle-relaxation … We do not know if using both traction and medicines for pain increases
your risks of serious side effects … What are the risks of acupressure, muscle-relaxation
therapy, and TENS? … There is not enough research to
say if these options have
any risks or can cause
any side effects
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
December 23, 2014 - Assessment of Methodological Risk of Bias of Individual Studies
Risk of bias of eligible studies will … across risk of bias approaches. … If the risk of bias
assessment tool is similar to our approach, we will separately assess risk of bias … We will calculate risk ratios (RR)
and absolute risk differences (RD) with the corresponding 95 percent … Chapter 8:
Assessing risk of bias in included studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis-future_research_1.pdf
February 01, 2013 - Thirteen comparative
studies reported risks. … Thus,
ES-2
there was insufficient evidence regarding the comparative risks of various NIT modalities … Thirteen comparative
studies reported risks. … Thus,
there was insufficient evidence regarding the comparative risks of various NIT modalities in … ), the extant literature does
not provide sufficient evidence to conclude whether safety concerns, risks
-
effectivehealthcare.ahrq.gov/sites/default/files/communicating_risk_international_king.ppt
January 01, 2005 - information tool for use by consumers/patients
Addresses treatment of a defined condition
Addresses risks … Information Products from Other Countries
How is risk and benefit communicated to health care consumers … Understanding NICE guidance—information for people who have or are at increased risk of cardiovascular … Strength of
Evidence
Yes Yes,
OTC meds,
NSAIDs, COX-2s,
Topicals, Supple-ments Yes, pain relief and risk … of CV event or GI bleeding Yes, sort out benefit, risk, cost of choices Narrative,
Q&A,
Price comparisonchart
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_consumer.pdf
January 01, 2016 - � Men aged 50 years or older have a higher risk of prostate cancer. … � The risk of prostate cancer is higher for men with a history of
prostate cancer in their family. … Your risk level can help you and your doctor decide what treatment
may be best for you. … Risk Level* PSA Level Gleason Score T-Score
Low risk† 10 or less 6 or less T1–T2a
Medium risk†† 10 … These may
include your risk level, your age, and any other health problems.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_research-protocol.pdf
January 27, 2012 - for whom acamprosate
and oral naltrexone are not suitable, or prefer disulfiram and understand the relative … risks
of taking the drug; and (3) to have specialist and competent staff administer
pharmacological … Assessment of Methodological Risk of Bias of Individual Studies—To
assess the risk of bias (i.e., internal … A study assessed as high risk of bias has
significant risk of bias (e.g., stemming from serious issues … For binary outcomes
(e.g., adverse events), we will calculate risk differences between groups or
risk
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_clinician.pdf
May 01, 2016 - to 0.94) ���
Table 2: Comparative Effectiveness of Core-Needle Biopsy Methods in Women at Average Risk … Open surgical biopsy samples most or all of the lesion, so
it is considered to have a smaller risk of … However, open procedures may carry a greater risk
of complications, such as bleeding or infection, when … Studies on the accuracy of core-needle breast biopsies were
deemed to have moderate to high risk of … The applicability of findings to women at high risk
of breast cancer is uncertain because few studies
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0648-140819.pdf
June 24, 2014 - Staff-Generated PICO
Population(s): Adults with or at risk of having gout
Intervention(s): Clinical … Does the risk of adverse effects differ according to patient baseline diet and
fluid intake?
c. … Does the risk of adverse effects differ according to joint vs. systemic
involvement in gout? … In adults with a history of gout, what is the evidence that pharmacological therapies
to reduce risk … Does the risk of adverse effects differ according to patient baseline diet and
fluid intake?
c.
-
effectivehealthcare.ahrq.gov/sites/default/files/calcineurin-inhibitor_disposition-comments.pdf
March 15, 2016 - comparing the
immunosuppressive regimens designed to reduce or
eliminate exposure to CNI toxicity risks … be interesting
to know if it is possible to identify at what point in the
withdrawal process the risks … It is not clear where
the benefits of minimization end and the risks of
withdrawal begin. … By indirectly endorsing this perspective, this
review risks exacerbating a trend toward overzealous … However, risks
and benefits will vary greatly
depending on what type of
donor organ is being used,