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Total Results: 2,117 records

Showing results for "risk".

341. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
     January 01, 2007 - Many questions remain about the risks of these agents across a spectrum of adverse events from relatively … Finally, very little is known about the benefits or risks of these drugs in different patient subgroups … All the same issues noted for RA of short- and long-term risks and safety, as well as performance in … withdrawals attributed to adverse events were not significantly different for leflunomide vs. methotrexate (relative … risk [RR], 1.19; 95-percent CI, 0.89-1.6) or sulfasalazine (RR, 0.77; 95-percent CI, 0.45-1.33).

342. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests_executive.pdf
     February 01, 2006 - For women with relevant demographic risk factors (e.g., age, family history) and clinical risk factors … For women at this average level of risk of cancer after an abnormal mammogram, based upon the tests’ … the risk that she has cancer even if the test is negative. … acceptable level of risk for a diagnostic test to reliably preclude biopsy, none of these tests was … sufficiently accurate to replace biopsy for women at average risk of breast cancer.

343. Disposition of Comments for Interventions for the Prevention of Posttraumatic Stress Disorder (PTSD) in Adults After Exposure to Psychological Trauma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_disposition-comments.pdf
     April 02, 2013 - We did not use a numerical scoring system to determine the risk of bias. … to discuss the studies with “high risk of bias,” while noting that caveat. … This means that <10% of trauma exposed (lifetime) are at risk of PTSD. … to identify who is at risk are not feasible. … on risk confirming that exposure itself is one of the weakest risk predictors and use of this as a

344. Antipsychotics for the Prevention and Treatment of Delirium: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/delirium-research-protocol.pdf
     June 01, 2018 - Older age is an important independent risk factor for delirium,2 with a prevalence >70% in critically … higher heterogeneity.24 For dichotomous outcomes, we will calculate a pooled effect estimate of the relative … A systematic review of risk factors for delirium in the ICU. … Does antipsychotic drug use increase the risk of long term mortality? … ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions.

345. Nonpharmacologic Treatment for Maternal Mental Health Conditions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-health-pregnant-protocol.pdf
     August 24, 2023 - Assessment of Methodological Risk of Bias of Individual Studies: We will evaluate each study for risk … Depression and anxiety in early pregnancy and risk for preeclampsia. … Untreated prenatal maternal depression and the potential risks to offspring: a review. … We will not assess risk of bias for these studies; except that we will assess risk of bias of large … study for risk of bias and methodological quality.

346. Tympanostomy Tubes in Children With Otitis Media (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-executive-170523.pdf
     May 01, 2017 - difference in cumulative hazard of recurrent AOM or in efficacy, defined as one minus the adjusted relative … Risk of bias for various outcomes in high risk populations was rated as high. … Risk of bias was rated moderate overall. … Tympanostomy tube outcomes in children at risk and not at-risk for developmental delays. … Panel 1: Epidemiology, natural history, and risk factors.

347. Crosscutting-Horizon-Scan-High-Impact-1506 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1506.pdf
     June 01, 2015 -  Key Expert Comments: Programs such as MSHOP may address an unmet need for reducing surgical risks … that clinicians would be likely to adopt a MSHOP-like program based on the potential to decrease risks … Most experts commenting on this intervention agreed that an unmet need exists for reducing surgical risks … Unmet need and health outcomes: An unmet need exists to decrease surgical risks and complications, … biggest hurdle, which is patient compliance.67 Acceptance and adoption: The potential to decrease risks

348. Rapid Evidence Product: Misuse of ADHD Prescription Stimulants in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-adhd-prescription-rapid-research.pdf
     July 01, 2025 - Systematic Review: Nonmedical Use of Prescription Stimulants: Risk Factors, Outcomes, and Risk Reduction … Risk of Incident Psychosis and Mania With Prescription Amphetamines. … reduced when studies had serious risk of bias. … reported more symptomatology than low-risk non- users (p .001)] Why? … .001) and perceptions of not having to worry about potential negative side effects and other health risks

349. Medical Care for Adults with Down Syndrome (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/care-adults-down-syndrome-protocol.pdf
     July 09, 2024 - , and race.15-17 With the increase in life expectancy, knowledge of the physical and mental health risks … Assessment of Methodological Risk of Bias of Individual Studies Risk of bias of included KQ studies … We will calculate risk ratios (RR) and absolute risk differences (RD) with the corresponding 95 percent … difference ROB Risk of bias ROBINS-I Risk OF Bias In Non-Randomized Studies-of Interventions … or risk?

350. Fiber Intake and Laxation Outcomes (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/fiber-intake-protocol.pdf
     August 15, 2023 - study for risk of bias and methodological quality during data extraction. … , is at high risk, then the trial will be considered to be at moderate risk of bias • If two or more … risk, then the trial will be considered to be at high risk of bias • Trials with no identified risk … of bias or quality issues will be considered to be at low risk of bias If pertinent, the risk of … Polygenic risk scores: from research tools to clinical instruments.

351. Cannabis-2022-Surv-Rep-4-Tables-G1-2 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-4-tables-G1-2.xlsx
     January 01, 2022 - Risk of bias of cannabis RCTs Author, Year Randomization Adequate? … Risk of bias of cannabis RCTs Table G-2. ROB Cohort Studies Table G-2. … Risk of bias of cannabis cohort studies Author, Year Did the Study Attempt To Enroll All (or a Random … Risk of Bias Bestard, 2011 Yes Yes Yes No Yes Yes/No No Yes Moderate Campbell, 2018 Yes Unclear Yes … Risk of bias of cannabis cohort studies

352. Cannabis-2023-Surv-Rep-1-App-G (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-1-app-G.xlsx
     January 01, 2023 - Risk of bias of cannabis RCTs Author, Year Randomization Adequate? … Risk of bias of cannabis RCTs Table G-2. ROB Cohort Studies Table G-2. … Risk of bias of cannabis cohort studies Author, Year Did the Study Attempt To Enroll All (or a Random … Risk of Bias Bestard, 2011 Yes Yes Yes No Yes Yes/No No Yes Moderate Campbell, 2018 Yes Unclear Yes … Risk of bias of cannabis cohort studies

353. Cannabis-2023-Surv-Rep-4-Tables-F1-F-2 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-4-tables-F1-F-2.xlsx
     January 01, 2023 - Risk of bias of cannabis RCTs Author, Year Randomization Adequate? … Risk of bias of cannabis RCTs Table F-2. ROB Cohort Studies Table F-2. … Risk of bias of cannabis cohort studies Author, Year Did the Study Attempt To Enroll All (or a Random … Risk of Bias Bestard, 2011 Yes Yes Yes No Yes Yes/No No Yes Moderate Campbell, 2018 Yes Unclear Yes … Risk of bias of cannabis cohort studies

354. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_disposition-comments.pdf
     January 01, 2015 - Most results were presented as relative risks. … Some of this, however, is difficult to clinically interpret because relative risks may be high yet … While the relative risk was 1.0 in ADOPT, the absolute risk difference was 0.1% (indicating a slightly … Therefore, baseline risks were different in the trials. … We have clarified that these are relative risk reductions from randomized controlled trials when used

355. Improving the Management of Menopausal Symptoms in Perimenopausal and Early Postmenopausal Women: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopausal-symptoms-protocol.pdf
     October 15, 2024 - For estrogen alone, although the risks of blood clots and stroke were higher during treatment, there … was no elevated risk and possibly a reduced risk of breast cancer. … The benefits and risks of this customized strategy have not been studied.20-22 Understanding how to … For trials and NRSIs, we will synthesize dichotomous outcomes using relative effect measures (e.g., relative … risk, hazard ratios, odds ratios).

356. Improving the Management of Menopausal Symptoms in Perimenopausal and Early Postmenopausal Women: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopausal-symptoms-protocol-final.pdf
     October 15, 2024 - For estrogen alone, although the risks of blood clots and stroke were higher during treatment, there … was no elevated risk and possibly a reduced risk of breast cancer. … The benefits and risks of this customized strategy have not been studied.20-22 Understanding how to … For trials and NRSIs, we will synthesize dichotomous outcomes using relative effect measures (e.g., relative … risk, hazard ratios, odds ratios).

357. Update Topic Brief CER 27 NSD FINAL_SJ final (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_overview.pdf
     January 17, 2014 - a number of potential adverse events associated with rosiglitazone (e.g. increased cardiovascular risks … ), pioglitazone (e.g. increased risk of bladder cancer), the combination of pioglitazone with insulin … (e.g. cardiac failure), and GLP-1 analogs or DPP-4 inhibitors (e.g. increased risk of pancreatitis)

358. Colon-Cancer-Gene-Profiling Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_research-protocol.pdf
     March 13, 2012 - A number of negative prognostic factors (factors associated with increased risk of recurrence) have … Identifying the individuals in whom the potential benefits of chemotherapy outweigh the risks is challenging … T4 tumor) may be inadequate for determining individual risk. … On the other hand, introducing routine testing without a clear understanding of benefits and risks could … obtained with standard risk factors?

359. bipolar-disorder-treatment-protocol-140623 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
     June 23, 2014 - when considering a specific treatment option versus no treatment, they would need to consider the risks … We define a “direct” harm as harm a patient risks by virtue of receiving the treatment and is part of … What can we do to mitigate the side effects of pharmacological treatments that create other medical risks … quality.15 Study-level risk of bias must be assessed using validated risk of bias tools appropriate … Using a random effects model, we will calculate risk ratios (RR) and absolute risk differences (RD)

360. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
     December 01, 2011 - The strength of evidence for higher risks of weight gain with mirtazapine than with other antidepressants … Severe Adverse Events The strength of the evidence on the comparative risks of second-generation antidepressants … trials and observational studies were too small and study durations too short to assess the comparative risks … yield conflicting information about the comparative risk of seizures. … hepatotoxicity about the comparative risk of hepatotoxicity.