-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_disposition-comments.pdf
April 02, 2013 - We did not use a numerical scoring system
to determine the risk of bias. … to discuss the studies with “high risk of bias,” while
noting that caveat. … This means that <10%
of trauma exposed (lifetime) are at risk of PTSD. … to identify
who is at risk are not feasible. … on risk confirming that exposure itself is one of the
weakest risk predictors and use of this as a
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests_executive.pdf
February 01, 2006 - For women with relevant demographic risk factors
(e.g., age, family history) and clinical risk factors … For
women at this average level of risk of cancer after
an abnormal mammogram, based upon the tests’ … the risk that she has cancer even if the test is
negative. … acceptable level of risk for a diagnostic test to
reliably preclude biopsy, none of these tests was … sufficiently accurate to replace biopsy for women
at average risk of breast cancer.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-executive-170523.pdf
May 01, 2017 - difference in
cumulative hazard of recurrent AOM or in efficacy, defined
as one minus the adjusted relative … Risk of bias for various outcomes
in high risk populations was rated as high. … Risk of bias was rated moderate overall. … Tympanostomy tube
outcomes in children at risk and not at-risk for developmental
delays. … Panel 1:
Epidemiology, natural history, and risk factors.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/care-adults-down-syndrome-protocol.pdf
July 09, 2024 - , and race.15-17 With
the increase in life expectancy, knowledge of the physical and mental health risks … Assessment of Methodological Risk of Bias of Individual Studies
Risk of bias of included KQ studies … We will calculate
risk ratios (RR) and absolute risk differences (RD) with the corresponding 95 percent … difference
ROB Risk of bias
ROBINS-I Risk OF Bias In Non-Randomized Studies-of Interventions … or risk?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-adhd-prescription-rapid-research.pdf
July 01, 2025 - Systematic Review: Nonmedical Use of
Prescription Stimulants: Risk Factors, Outcomes,
and Risk Reduction … Risk of
Incident Psychosis and Mania With Prescription
Amphetamines. … reduced when studies had serious risk of bias. … reported more
symptomatology than low-risk non-
users (p .001)]
Why? … .001) and
perceptions of not having to worry
about potential negative side effects
and other health risks
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_disposition-comments.pdf
January 01, 2015 - Most results were presented as relative risks. … Some of this,
however, is difficult to clinically interpret because
relative risks may be high yet … While the relative risk
was 1.0 in ADOPT, the absolute risk difference
was 0.1% (indicating a slightly … Therefore, baseline risks were different in the
trials. … We have clarified that these are
relative risk reductions from randomized
controlled trials when used
-
effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1506.pdf
June 01, 2015 - Key Expert Comments: Programs such as MSHOP may address an unmet need for
reducing surgical risks … that clinicians would be likely to adopt a MSHOP-like
program based on the potential to decrease risks … Most experts commenting on this intervention agreed that an unmet need exists for reducing
surgical risks … Unmet need and health outcomes: An unmet need exists to decrease surgical risks and
complications, … biggest hurdle, which is patient compliance.67
Acceptance and adoption: The potential to decrease risks
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fiber-intake-protocol.pdf
August 15, 2023 - study for risk of bias and methodological quality during data
extraction. … , is at high risk, then the trial will be considered to be at moderate risk of
bias
• If two or more … risk, then the trial will be considered to be at high
risk of bias
• Trials with no identified risk … of bias or quality issues will be considered to be at low
risk of bias
If pertinent, the risk of … Polygenic risk scores: from research tools to clinical instruments.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-4-tables-F1-F-2.xlsx
January 01, 2023 - Risk of bias of cannabis RCTs
Author, Year Randomization Adequate? … Risk of bias of cannabis RCTs
Table F-2. ROB Cohort Studies
Table F-2. … Risk of bias of cannabis cohort studies
Author, Year Did the Study Attempt To Enroll All (or a Random … Risk of Bias
Bestard, 2011 Yes Yes Yes No Yes Yes/No No Yes Moderate
Campbell, 2018 Yes Unclear Yes … Risk of bias of cannabis cohort studies
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-4-tables-G1-2.xlsx
January 01, 2022 - Risk of bias of cannabis RCTs
Author, Year Randomization Adequate? … Risk of bias of cannabis RCTs
Table G-2. ROB Cohort Studies
Table G-2. … Risk of bias of cannabis cohort studies
Author, Year Did the Study Attempt To Enroll All (or a Random … Risk of Bias
Bestard, 2011 Yes Yes Yes No Yes Yes/No No Yes Moderate
Campbell, 2018 Yes Unclear Yes … Risk of bias of cannabis cohort studies
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-1-app-G.xlsx
January 01, 2023 - Risk of bias of cannabis RCTs
Author, Year Randomization Adequate? … Risk of bias of cannabis RCTs
Table G-2. ROB Cohort Studies
Table G-2. … Risk of bias of cannabis cohort studies
Author, Year Did the Study Attempt To Enroll All (or a Random … Risk of Bias
Bestard, 2011 Yes Yes Yes No Yes Yes/No No Yes Moderate
Campbell, 2018 Yes Unclear Yes … Risk of bias of cannabis cohort studies
-
effectivehealthcare.ahrq.gov/sites/default/files/brooks_eccs2012.pdf
January 01, 2012 - whether to be screened for prostate cancer,
after receiving information about the uncertainties, risks … increases
the chance of findin prostate
cancer at an earlier stage.
• Screening might lower a man’s risk … tests
to
find it early.
• We don’t
yet
know
if the benefits of testing
outweigh the risks … Slide 16: Balanced Discussion of Pros
and Cons
Two
images displaying benefits and risks titled
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-infection-prevention-mdro-rapid-research.pdf
April 01, 2024 - prevention and control practice (for example, for interventions of long
duration, the pooled random effects relative … Unclear risk High risk Low risk Low risk Unclear risk
McConeghy et al.,
201744
Unclear risk Low … risk High risk Low risk Low risk Unclear risk
Miller et al, 202346 Low risk Unclear risk High risk … Low risk Low risk Low risk
Ray et al., 201751 Unclear risk Low risk High risk Low risk High risk Unclear … risk
Salgado et al.,
201352
Low risk Unclear risk Low risk Low risk Low risk Unclear risk
Table
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_research-protocol.pdf
March 13, 2012 - A number of negative prognostic factors (factors associated with increased risk of
recurrence) have … Identifying the individuals in whom the potential benefits of chemotherapy outweigh
the risks is challenging … T4 tumor) may be inadequate for determining
individual risk. … On the other hand, introducing routine
testing without a clear understanding of benefits and risks could … obtained with standard risk factors?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
December 01, 2011 - The strength of
evidence for higher risks of weight gain with
mirtazapine than with other antidepressants … Severe Adverse Events
The strength of the evidence on the comparative risks
of second-generation antidepressants … trials and observational studies were too
small and study durations too short to assess the
comparative risks … yield
conflicting information about the comparative risk of seizures. … hepatotoxicity about the comparative risk of hepatotoxicity.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
June 23, 2014 - when considering a specific treatment option versus no treatment, they would
need to consider the risks … We define a “direct”
harm as harm a patient risks by virtue of receiving the treatment and is part of … What can we do to mitigate the side effects of
pharmacological treatments that create other medical risks … quality.15 Study-level risk of bias must be assessed using validated
risk of bias tools appropriate … Using a random
effects model, we will calculate risk ratios (RR) and absolute risk differences (RD)
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopausal-symptoms-protocol-final.pdf
October 15, 2024 - For estrogen alone, although the risks
of blood clots and stroke were higher during treatment, there … was no elevated risk and possibly a
reduced risk of breast cancer. … The
benefits and risks of this customized strategy have not been studied.20-22
Understanding how to … For trials
and NRSIs, we will synthesize dichotomous outcomes using relative effect measures (e.g.,
relative … risk, hazard ratios, odds ratios).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopausal-symptoms-protocol.pdf
October 15, 2024 - For estrogen alone, although the risks
of blood clots and stroke were higher during treatment, there … was no elevated risk and possibly a
reduced risk of breast cancer. … The
benefits and risks of this customized strategy have not been studied.20-22
Understanding how to … For trials
and NRSIs, we will synthesize dichotomous outcomes using relative effect measures (e.g.,
relative … risk, hazard ratios, odds ratios).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-evidence-communication_executive.pdf
November 01, 2013 - Risk-of-Bias Assessment of Individual Studies
Two reviewers independently rated the risk of bias of … uncertainty are as follows:
• Communicating precision—Studies found mixed
effects of presenting numeric risks … Benefts for me or risks for others: a cross-
culture investigation of the effects of message frames and … Does information
about risks and benefts improve the decision-making
process in cancer screening - … Impact of
information about risks and benefts of cancer screening on
intended participation.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-911-workforce-mental-health-protocol-amendment.pdf
January 22, 2024 - EMS clinicians have been shown to be at high risk for anxiety, depression,
posttraumatic stress disorder … Assessment of Risk of Bias in Individual Studies: We will evaluate each study for risk of bias and
methodological … As reported data allow, we will primarily evaluate relative risks (RRs) for dichotomous outcomes
https … The Cochrane Collaboration's tool for assessing risk
of bias in randomised trials. Bmj. … ROBINS-I: a tool for assessing risk of bias in non-
randomised studies of interventions. Bmj.