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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-update-surv-rep-1-apps-G1-2.xlsx
January 01, 2022 - Risk of bias of cannabis RCTs
Author, Year Randomization Adequate? … Risk of bias of cannabis RCTs
Table G-2. ROB Cohort Studies
Table G-2. … Risk of bias of cannabis cohort studies
Author, Year Did the Study Attempt to Enroll All (or a Random … Risk of Bias
Bestard, 2011 Yes Yes Yes No Yes Yes/No No Yes Moderate
Campbell, 2018 Yes Unclear Yes … Risk of bias of cannabis cohort studies
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effectivehealthcare.ahrq.gov/sites/default/files/decide16final-mortality-risk-in-copd-pts-using-theophylline.pdf
December 01, 2009 - Mortality risk in chronic obstructive pulmonary disease
patients using theophylline. … Compared to similar regimens, patients in regimens that included theophylline had
slightly increased risks … these increased risks were generally small (HR of 1.1 to 1.3). … patient-reported outcomes in a real-world setting will be necessary to quantify
both the benefits and risks … Inhaled
corticosteroids and the risk of a first
exacerbation in COPD patients.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-management_research.pdf
December 01, 2009 - Mortality risk in chronic obstructive pulmonary disease
patients using theophylline. … Compared to similar regimens, patients in regimens that included theophylline had
slightly increased risks … these increased risks were generally small (HR of 1.1 to 1.3). … patient-reported outcomes in a real-world setting will be necessary to quantify
both the benefits and risks … Inhaled
corticosteroids and the risk of a first
exacerbation in COPD patients.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/fatty-acids-cardiovascular-disease_consumer.pdf
July 01, 2017 - People with high triglyceride levels may also
be at risk for CV disease. … May lower
the risk (in healthy
people)
Do not lower the risk
(in people with CV
disease or those … at risk
for CV disease)
Not enough
research to know
Triglyceride level? … High levels of good cholesterol lower the risk
of CV disease. … High levels of bad cholesterol increase the
risk of CV disease.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-brain-injury_executive.pdf
April 01, 2011 - which treatment modalities are equivalent or superior
with respect to benefits, short- and long-term risks … Risk factors. Data are sparse to assess whether severity
of injury influences risk of depression. … , such that those age 60 and older were at
lowest risk.125 In another study aiming at predicting risk … (relative risk [RR] = 1.27; 95 percent confidence
interval [CI]: 1.07, 1.52) of new but not recurrent … with risk.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disorders-protocol.pdf
January 31, 2023 - assess risk of bias of included studies. … Each
study will be dual reviewed for risk of bias by two team members. … points on a 0 to 100-point scale
• SMD >0.8
• RR/OR ≥2.0
MD = mean difference; OR = odds ratio; RR = relative … The social ecology of community and neighborhood and risk for
antisocial behavior. … Assessing the Risk of Bias in
Systematic Reviews of Health Care Interventions.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medication-therapy-management_executive.pdf
November 01, 2014 - A broadly defined scope for this review risks including
studies that may be too different from each … A narrowly
defined scope for this review risks the omission of studies
that met the definition of MTM … In other words, we evaluated trials with potential
randomization failure for the same risks of bias … therapy management; NA = not applicable; OR = odds ratio;
RCT = randomized controlled trial; RRR = relative … risk ratio.
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effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1512.pdf
December 01, 2015 - is an example of an initiative aimed at improving surgical outcomes by assessing
patient-specific risks … Key Expert Comments: Programs such as MSHOP may address an unmet need for
reducing surgical risks … that clinicians would be likely to adopt a MSHOP-like
program based on the potential to decrease risks … Unmet need and health outcomes: An unmet need exists to decrease surgical risks and
complications, … biggest hurdle, which is patient compliance.68
Acceptance and adoption: The potential to decrease risks
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_executive.pdf
April 01, 2012 - Many questions remain about the risks of
these agents across a spectrum of adverse events, from
relatively … Finally, very little
is known about the benefits or risks of these drugs in
different patient subgroups … Low
Risk for injection site reactions apparently
highest with anakinra. … Low
Mixed evidence on differences in the risk for rare
but severe adverse events. … Biologics neither decreased nor
increased cardiovascular risks in the elderly.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-heart_research-protocol.pdf
April 18, 2012 - Evidence-based Practice Center Systematic Review Protocol
Project Title: Strategies To Improve Cardiovascular Risk … second-generation
antipsychotics) also may contribute to the development of CVD by increasing the risk … Comorbid Risk Factors in
People With SMI
Pharmacological Treatments Patient-Focused Behavioral … CVD
Analytic Framework for Strategies To Improve Cardiovascular Risks Factors in People With Serious … Diet, smoking and cardiovascular risk in people with schizophrenia:
descriptive study.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement-may-2025.pdf
January 01, 2025 - to inform the implementation of
interventions for children, adolescents, and young adults at high risk … Assessment of the Risk of Bias of Individual Studies
We will evaluate the risk of bias of the included … of available studies (in a particular comparison) have
high or unclear risk of bias. … How have the SSRI antidepressants affected suicide risk? … RoB 2: a revised tool for assessing risk of bias in
randomised trials.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
January 01, 2007 - Many questions remain
about the risks of these agents across a spectrum of
adverse events from relatively … Finally, very little is known about
the benefits or risks of these drugs in different patient
subgroups … All the
same issues noted for RA of short- and long-term risks
and safety, as well as performance in … withdrawals attributed to adverse events were not
significantly different for leflunomide vs. methotrexate
(relative … risk [RR], 1.19; 95-percent CI, 0.89-1.6) or
sulfasalazine (RR, 0.77; 95-percent CI, 0.45-1.33).
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effectivehealthcare.ahrq.gov/sites/default/files/s13.pdf
October 01, 2007 - Historically, those who investigate the effects of mar-
keted pharmaceuticals have focused on the risk … Finally, in recent years, there has been
an increased focus on risk management of drugs (ie, modifi- … Variation
in risk can also depend on duration. … Patterns of risk related to last exposure can
also vary. … Managing the risks from medical
product use: creating a risk management framework. http://www.fda.
gov
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effectivehealthcare.ahrq.gov/sites/default/files/s123.pdf
October 01, 2007 - ORIGINAL ARTICLE
Heterogeneity and the Interpretation of Treatment Effect
Estimates From Risk Adjustment … Results: Risk adjustment models yielded average survival estimates
similar to trial results. … Both confounding risks and the extent that
the estimates can be generalized across the patient population … curve.
0
UO
optimistic BCSI relative survival risk curve. … Table 3 contains the risk adjusted linear probability
model and the IV survival models.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-911-workforce-disposition-comments.pdf
November 01, 2022 - examined the risk for COVID-19 infection among EMS providers
in King County, Washington. … of COVID-19 infection and that overall risk to EMS
providers was very low. … "
in fact some studies say lower risk than the general public. … Example -
medical waste studies do not show that medical waste poses
a risk. … , proper patient care
risk reduction practices as well as personal protection.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/delirium-research-protocol.pdf
June 01, 2018 - Older age is an
important independent risk factor for delirium,2 with a prevalence >70% in critically … higher heterogeneity.24 For
dichotomous outcomes, we will calculate a pooled effect estimate of the relative … A systematic review of risk factors for
delirium in the ICU. … Does antipsychotic drug use increase the risk of long
term mortality? … ROBINS-I: a tool for assessing risk of
bias in non-randomised studies of interventions.
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effectivehealthcare.ahrq.gov/sites/default/files/cer-239-acute-migraine-evidence-summary.pdf
December 01, 2020 - inflammatory drugs), dihydroergotamine, antiemetics, and acetaminophen, reduce
pain but increase the risk … • No studies evaluate instruments for predicting risk of opioid misuse, opioid use
disorder or overdose … , or evaluate risk mitigation strategies to be used when
prescribing opioids for episodic migraine … overdose; or evaluated risk mitigation strategies in episodic migraine. … For example, lasmiditan increased the risk of serious
adverse events compared with placebo.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/joint-replacement-disposition-comments.pdf
November 03, 2021 - • Clarification of risk-of-bias assessment: Several reviewers noted the challenges in achieving a … low-risk-of-bias rating, particularly given the challenge of blinding personnel and patients. … We noted that
while the evidence from high-risk-of-bias studies should be considered cautiously, a … high-risk-of-bias rating does not mean such studies have no evidentiary value or that they are
intrinsically … We followed AHRQ methods to not remove studies deemed to be at high
risk of bias, but present the risk
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-genetic_methods.pdf
July 01, 2012 - What health risks can be identified for follow-up testing and/or intervention?
35. … Tests for BRCA mutations may be used to predict the risk for breast and
ovarian cancer in high-risk … women (i.e., those with a family history suggesting increased risk). … Lyon, France: IARC Monogr Eval Carcinog
Risks Hum; 1999. p. 23-36.
45. … Genetic risk assessment: recommendation
statement.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-health-pregnant-protocol.pdf
August 24, 2023 - Assessment of Methodological Risk of Bias of Individual Studies:
We will evaluate each study for risk … Depression and anxiety in early pregnancy and risk for
preeclampsia. … Untreated prenatal maternal depression and the potential
risks to offspring: a review. … We will
not assess risk of bias for
these studies; except that
we will assess risk of bias
of large … study for risk of bias and
methodological quality.