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Total Results: 2,117 records

Showing results for "risk".

301. Disposition of Comments for CER 147 Menopausal Symptoms: Comparative Effectiveness of Therapies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_disposition-comments.pdf
     March 05, 2015 - We have added to applicability sections in KQ2 potential differences in relative risk in gallbladder … It is our view that issues concerning age and risks are adequately highlighted. … In the Million Women Study the relative risk was lower with transdermal administration, but not eliminated … and the risk-benefit profile of estrogen therapy. … increase the risk of endometrial cancer.’

302. Rapid Response_The Association Between Outcomes and Dental Services in Persons With Autoimmune Disease Treated With Biologics and Other Immunosuppressants: A Rapid Response Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/autoimmune-disease-rapid-research.pdf
     November 01, 2024 - risk of bias High risk of bias Critically low confidence Critical risk of bias n/a 2.5 Data Synthesis … treatment; RA: rheumatoid arthritis; RCT: randomized controlled trial; RF: rheumatoid factor; RR: relative … of bias RR Relative risk SDAI Simple disease activity index SLE Systemic lupus erythematosus SLEDAI … Patients With RA Risk of Bias Domain D1 Risk of Bias Domain D2 Risk of Bias Domain D3 … Risk of Bias Domain D4 Risk of Bias Domain D5 Risk of Bias Domain D6 Risk of Bias

303. Executive summary_Comparative Effectiveness Review No. 250_Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2025 Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-executive-sum.pdf
     January 01, 2025 - There may be a large increased risk of dizziness and sedation (SOE: low) and a moderate increased risk … THC plus CBD is probably associated with large increased risk of nausea (SOE: moderate). … -point scale • SMD >0.8 • RR/OR ≥2.0 Abbreviations: MD = mean difference; OR = odds ratio; RR = relative … risk; SMD = standardized mean difference. … , nausea, sedation); high THC to CBD products were also associated with increased risk of study WAEs

304. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-risk-drugs-protocol.pdf
     July 27, 2023 - Center Rapid Response Protocol Project Title: Making Healthcare Safer IV: Protocols for High-Risk … of PSPs, the primary reviewer will use the Cochrane Collaboration’s tool for assessing the risk of … The risk of bias assessments will focus on the main outcome of interest in each study. … The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. … ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions.

305. Title (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/obesity-child_research-protocol.pdf
     March 31, 2010 - 5 However, the patterns are complicated, and not all low-income or minority groups are at high risk …  Poor (high risk of bias). … differences or relative risks using a DerSimonian and Laird random effects model. … differences or relative risks with 95% confidence. … of the degree to which the study population, interventions, outcomes, and settings are relevant to risks

306. Technical Brief Disposition of Comments Report for Gene Expression Profiling for Predicting Outcomes in Stage II Colon Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colon-cancer-gene-profiling_disposition-comments.pdf
     December 14, 2012 - exists to support the clinical utility of the GEP tests to alter or improve health outcomes and the risks … The 5-year distant-metastasis free survival was 95% for low risk patients and 80% for high risk patients … The 3-year RFS was 91% for Low Risk and 74% for High Risk patients with a HR of 2.9 (p=0.001).” … ColoPrint better distinguishes low and high risk groups as compared to risk assessment using current … ColoPrint better distinguishes low and high risk groups as compared to risk assessment using current

307. Executive Summary_Comparative Effectiveness Review No. 271: Nonpharmacologic Treatments for Maternal Mental Health Conditions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-271-mental-health-pregnant-executive-summary.pdf
     July 01, 2024 - For studies of individuals with depressive or anxiety disorders, data extraction and risk of bias assessment … We assessed the risk of bias and • Nonpharmacologic treatment for post-traumatic stress disorder (PTSD … Where sufficient comparable studies were available, we conducted meta-analyses of relative risk (RR) … Abbreviations: CBT = cognitive behavioral therapy, CI = confidence interval, IPT = interpersonal therapy, RR = relative … risk, SMD = standardized mean difference, SoE = strength of evidence, TAU = treatment as usual, EPDS

308. Making Healthcare Safer IV_Rapid Response_Deprescribing To Reduce Medication Harms in Older Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-deprescribing.pdf
     February 01, 2024 - Low Risk Uncertain Risk Low Risk Low Risk Campbell, 201944 Low Risk Uncertain Risk High Risk Low Risk … Low Risk Low Risk Campbell, 202143 Low Risk Uncertain Risk High Risk High Risk Low Risk High Risk … Herrinton, 202346 Low Risk Low Risk High Risk High Risk Low Risk Low Risk Kuntz, 201948 Low Risk Uncertain … Risk High Risk High Risk Low Risk Low Risk Vasilevskis, 202352 Low Risk Uncertain Risk High Risk High … Risk Low Risk Uncertain Risk Note: For attrition, 80% followup used to assign low risk; 70%–80% =

309. Methods-Guidance-Applicability Methods (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-applicability_methods.pdf
     January 01, 2011 - studies of patients with and without heart disease may be useful for estimating the gastrointestinal risks … For example, although statins reduce risks of fatal and nonfatal coronary events comparably in populations … at high or lower risk of heart disease, the absolute benefits in high-risk populations such as those … Clinical experts think that age and comorbidity affect benefits and risks of aggressive therapy (by … creating competing risks which reduce the benefits of aggressive interventions and by increasing risks

310. Methods Guide Atkins (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/methods_guide_atkins.pdf
     January 01, 2011 - studies of patients with and without heart disease may be useful for estimating the gastrointestinal risks … For example, although statins reduce risks of fatal and nonfatal coronary events comparably in populations … at high or lower risk of heart disease, the absolute benefits in high-risk populations such as those … Clinical experts think that age and comorbidity affect benefits and risks of aggressive therapy (by … creating competing risks which reduce the benefits of aggressive interventions and by increasing risks

311. Dispostion of Comments Report for Screening for Hepatitis C Virus Infection in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_disposition-comments.pdf
     November 27, 2012 - perioperative mortality (the largest series of patients with HCV infection found no deaths) as well as risks … of CV events, and large risks of long-term impotence/ incontinence). … These risks should be noted in the background section. Thank you for your comment. … testing (if treatment is effective) unless there is a compelling cost reason to avoid it or the risks … the limited time available in primary care visits and the awkwardness of discussing the behavioral risks

312. Gout Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive.pdf
     March 01, 2016 - Assessment of Methodological Risk of Bias of Individual Studies Risk of bias (study quality) of individual … optimal duration of such therapy has not been experimentally tested, and the comparative benefits/risks … Risk factors for gout and prevention: a systematic review of the literature. … Cherry consumption and decreased risk of recurrent gout attacks. … Multiple Risk Factor Intervention Trial.

313. Evidence-based Practice Center Systematic Review Protocol: Therapies for Clinically Localized Prostate Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-protocol_amended110619.pdf
     November 02, 2019 - We will not extract data from high risk of bias studies or for outcomes that are high risk of bias. … Assessment of Methodological Risk of Bias of Individual Studies: Risk of bias of eligible RCTs will … risk of bias assessment. … We will calculate risk ratios (RR) and absolute risk differences (RD) with the corresponding 95 percent … Jung JH, Risk MC, Goldfarb R, et al.

314. Major-Depressive-Disorder Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_research-protocol.pdf
     November 24, 2014 - KQ 3a: In adult patients with MDD, what are the comparative risks of harms between SGAs and nonpharmacological … KQ 3b: Do the risks of treatment harms vary by MDD severity? … KQ 4: Do the benefits and risks of harms of these treatment options differ by subgroups of patients … Assessment of Methodological Risk of Bias of Individual Studies: To assess the risk of bias (internal … and nonpharmacological therapies KQ3a: In adult patients with MDD, what are the comparative risks

315. Cer-250-Cannabis-2024-Surv-Rep-Update-Tables-F1-2 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-tables-f1-2.xlsx
     January 01, 2024 - Risk of bias of cannabis RCTs Author, Year Randomization Adequate? … Risk of bias of cannabis RCTs Table F-2. ROB Cohort Studies Table F-2. … Risk of bias of cannabis cohort studies Author, Year Did the Study Attempt To Enroll All (or a Random … Risk of Bias Bestard, 2011 Yes Yes Yes No Yes Yes/No No Yes Moderate Campbell, 2018 Yes Unclear Yes … Risk of bias of cannabis cohort studies image1.jpeg

316. Nutrition as Prevention for Improved Cancer Outcomes (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/improved-cancer-outcomes-protocol_0.pdf
     December 01, 2021 - with cancer, with estimates ranging between 25 to 80 percent across patient populations.7-9 However, risk … pre-existing conditions (e.g., obesity), among other factors.8,10 Further, many factors may increase risk … All eligible studies addressing KQ 1-4 will be assessed for risk of bias. … reviewers will assess risk of bias of eligible studies. … Reviewers will consult to reconcile discrepancies in overall risk of bias.

317. Vitamin D and Calcium: A Systematic Review of Health Outcomes (Update) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/vitamin-d-calcium_executive.pdf
     September 01, 2014 - Two studies of school-age children observed inverse associations of serum 25(OH)D and risks for various … Vitamin D supplementation had no significant effect on all-cause mortality (summary relative risk [ … For the original report, no studies evaluated the risk of obesity or overweight. … for total cardiovascular disease and coronary heart disease risks. … Health risks and benefits from calcium and vitamin D supplementation: Women’s Health Initiative clinical

318. Cer-250-Cannabis-2025-Surv-Rep-Update-Tables-F1-2 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-tables-f1-2.xlsx
     January 01, 2025 - Risk of bias of cannabis RCTs Author, Year Randomization Adequate? … Risk of bias of cannabis RCTs Table F-2. ROB Cohort Studies Table F-2. … Risk of bias of cannabis cohort studies Author, Year Did the Study Attempt To Enroll All (or a Random … Risk of Bias Bestard, 2011 Yes Yes Yes No Yes Yes/No No Yes Moderate Campbell, 2018 Yes Unclear Yes … Risk of bias of cannabis cohort studies

319. Omega-3 Fatty Acids and Cardiovascular Disease: A Review of the Research for Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/fatty-acids-cardiovascular-disease_consumer.pdf
     July 01, 2017 - People with high triglyceride levels may also be at risk for CV disease. … May lower the risk (in healthy people) Do not lower the risk (in people with CV disease or those … at risk for CV disease) Not enough research to know Triglyceride level? … High levels of good cholesterol lower the risk of CV disease. … High levels of bad cholesterol increase the risk of CV disease.

320. Cannabis-2022-Update-Surv-Rep-1-Apps-G1-2 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-update-surv-rep-1-apps-G1-2.xlsx
     January 01, 2022 - Risk of bias of cannabis RCTs Author, Year Randomization Adequate? … Risk of bias of cannabis RCTs Table G-2. ROB Cohort Studies Table G-2. … Risk of bias of cannabis cohort studies Author, Year Did the Study Attempt to Enroll All (or a Random … Risk of Bias Bestard, 2011 Yes Yes Yes No Yes Yes/No No Yes Moderate Campbell, 2018 Yes Unclear Yes … Risk of bias of cannabis cohort studies image1.jpeg image2.jpeg