-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-prevention_executive.pdf
May 01, 2013 - level as determined by different risk-
assessment methods and/or by particular risk factors? … Increased Risk
Low Risk
Incidence of
Pressure Ulcer
Severity of
Pressure Ulcer
Harms
1
3
2 … When reported, we also extracted
relative measures of risk (relative risk [RR], odds ratio,
and hazards … Despite insufficient evidence to
determine whether use of risk-assessment instruments
reduces risk … Decisions
about whether to use risk-assessment instruments and
which risk-assessment instrument to
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/safety-vaccines-protocol.pdf
January 30, 2020 - Also, what are the risks of specific adverse events, the
frequency of events, and the certainty of the … frequency of potential side effects to
help them weigh the benefits of vaccines against potential risks … We will calculate the relative risk for the adverse events for all studies by
comparing the intervention … We will summarize the
absolute rate of adverse events as well as the relative risk, to facilitate the … Risk analysis : an official publication of
the Society for Risk Analysis. 2016;36(7):1297-314. doi:
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bladder-cancer-non-muscle-invasive_research-protocol.pdf
July 21, 2014 - number of available tests and testing strategies and potential trade-
offs in diagnostic accuracy, risks … groups, may be especially useful for patients in the intermediate and high risk groups. … of bias,” “medium risk of bias,” or “high
risk of bias.”15, 17
Studies rated “low risk of bias” will … We will not exclude studies rated as
being high risk of bias a priori, but high risk of bias studies … Each study evaluated will be independently reviewed for risk of bias by two team
members.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_executive.pdf
April 01, 2013 - Risk-of-Bias Assessment of Individual Studies
To assess the risk of bias (internal validity) of studies … fluoxetine,
paroxetine, and sertraline—most of the evidence was
insufficient to determine whether risks … Findings were insufficient to determine whether the risks
of other adverse events are increased. … approaches are more effective for victims
of particular types of trauma or to determine comparative
risks … The psychological
risks of Vietnam for U.S. veterans: a revisit with new data and
methods.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement.pdf
February 05, 2025 - to inform the implementation of
interventions for children, adolescents, and young adults at high risk … Assessment of the Risk of Bias of Individual Studies
We will evaluate the risk of bias of the included … of available studies (in a particular comparison) have
high or unclear risk of bias. … How have the SSRI antidepressants affected suicide risk? … RoB 2: a revised tool for assessing risk of bias in
randomised trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-260-improved-cancer-outcomes-executive-summary_0.pdf
May 01, 2023 - nutrition support in gastrointestinal and head
and neck cancers, 11 percent (n=12) were rated as low risk … of bias (higher
quality), 40 percent (n=46) medium risk of bias and 49 percent (n=56) as high risk
of … • Low- and medium-risk-of-bias studies reported mixed results on the effect of
nutrition interventions … malnutrition is
high among adults with cancer,5-7 but only 30 to 50 percent of cancer patients at risk … of bias (higher quality), 40 percent (n=46) medium risk of bias and 49
percent (n=56) high risk of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_executive.pdf
April 01, 2013 - profile
among adults with SMI at elevated risk of CVD. … factors in adults with SMI who
have elevated risk for CVD. … indices
(e.g., Framingham Risk Score). … These guidelines for the general population should
then be modified to consider the special risks for … or
cardiovascular events
Insufficient
information
Risk indices (e.g., Framingham Risk Score) and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/people-with-disabilities-protocol.pdf
January 16, 2024 - Assessment of Methodological Risk of Bias of Individual Studies
Risk of bias (internal validity) is … Studies will be rated as “low risk of bias,” “medium risk of bias,” or “high risk of bias.” … Studies
will be rated as “low risk of bias,” “medium risk of bias,” or “high risk of bias.” … Studies rated “low risk of bias” are considered to have the least risk of bias, and their results are … We will not exclude studies rated high risk of bias a priori, but high risk of bias studies will be
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
August 01, 2012 - health outcomes) and KQ3 (adverse events), the
conclusions are possibly out of date
- Teratogenic risks … indicating that hypotension is an unusual side effect for oral antiepileptic drugs,
whereas teratogenic risks … The expert
emphasized that the large amount of new information on pregnancy outcome risks in women … , questioned the choice of
side effects to review and thought
it is inexcusable that teratogenic
risks … specifying that it can cause
fetal harm when
administered to a pregnant
woman, and the benefits and
risks
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
August 01, 2012 - health outcomes) and KQ3 (adverse events), the
conclusions are possibly out of date
- Teratogenic risks … indicating that hypotension is an unusual side effect for oral antiepileptic drugs,
whereas teratogenic risks … The expert
emphasized that the large amount of new information on pregnancy outcome risks in women … , questioned the choice of
side effects to review and thought
it is inexcusable that teratogenic
risks … specifying that it can cause
fetal harm when
administered to a pregnant
woman, and the benefits and
risks
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-2.pdf
June 01, 2022 - Low risk Moderate risk Low risk Low risk Moderate risk
Gur, 20212 Moderate risk Moderate risk Low … risk Low risk Low risk Low risk
Yuan, 20213 Moderate risk Moderate risk Low risk Low risk Moderate risk … 4.74; I²
=N/A
Abbreviations: CI = confidence interval; mg = milligram; N/A = not applicable; RR = relative … 19.51; I² =N/A
Abbreviations: CI = confidence interval; mg = milligram; N/A = not applicable; RR = relative … risk
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-youth-disposition-comments.pdf
April 10, 2025 - One
could argue there are other risk factors like depression. … It could be important to put 0, unknown, etc. as
this is a high-risk sample. … more than the patient by
reassuring the clinician
and may reduce the visit
time to focus on other
risks … A majority of the studies
rated high risk of bias, a
few rated moderate risk,
but no studies rated … as
low risk.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/bereaved-persons-research-executive-summ.pdf
March 01, 2025 - • A small body of evidence has addressed the identification of bereaved people at
risk or with grief … How accurate are tools to identify bereaved
persons at risk for or with grief disorders? … What are the effectiveness, comparative
effectiveness, and harms of interventions for people at risk … We assessed the risk of bias, evaluated the applicability of studies, and determined
the SoE following … Abbreviations: CI = 95% confidence interval; N/A = not applicable, not available, no studies; RR = relative
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_executive.pdf
February 01, 2012 - Ewing’s
sarcoma family of tumors, and high-risk relapsed
Wilm’s tumor. … The four
required domains—risk of bias, consistency, directness,
and precision—were considered for … The decision to apply a high-risk procedure
such as HSCT to this population is not clear cut. … conditions addressed in this systematic review, evidence
is insufficient to draw conclusions as to the relative … risk-benefit ratio of HSCT versus other management
approaches.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research-protocol.pdf
September 02, 2016 - this methodology report is to examine the feasibility and additional
utility—in terms of impact on risk … For newly found studies,
we will record additional data and assess their risk of bias. … We will apply the same risk of bias
assessments as in the original review. … There is interest in comparative effectiveness of tympanostomy tubes in
high-risk and at-risk populations … Many randomized trials are relatively small, limiting their ability to
define risks of less common harms
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-risk-drugs-protocol.pdf
July 27, 2023 - Center Rapid Response Protocol
Project Title: Making Healthcare Safer IV:
Protocols for High-Risk … of PSPs, the
primary reviewer will use the Cochrane Collaboration’s tool for assessing the risk of … The risk of bias assessments will focus on the main outcome of
interest in each study. … The Cochrane Collaboration’s tool
for assessing risk of bias in randomised trials. … ROBINS-I: a tool for assessing risk of
bias in non-randomised studies of interventions.
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/postpartum-care-one-year-protocol-amendment.pdf
April 25, 2022 - parenthood, and consider future family planning, but also to mitigate immediate and lifelong
health risks … planning and contraception
o Adverse pregnancy outcomes associated with cardiometabolic disease
o Risks … Assessment of Methodological Risk of Bias of Individual Studies: We will evaluate each study for risk … The three
tools will include the Cochrane Risk of Bias Tool,20 the Risk of Bias in Nonrandomized Studies … Severe Maternal Morbidity and Risk of Mortality Beyond the
Postpartum Period.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-executive-sum.pdf
January 01, 2025 - There may be a large increased risk of dizziness and
sedation (SOE: low) and a moderate increased risk … THC plus CBD is probably associated with large
increased risk of nausea (SOE: moderate). … -point scale
• SMD >0.8
• RR/OR ≥2.0
Abbreviations: MD = mean difference; OR = odds ratio; RR = relative … risk; SMD = standardized mean difference. … , nausea, sedation); high THC to CBD products were also associated
with increased risk of study WAEs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autoimmune-disease-rapid-research.pdf
November 01, 2024 - risk of bias High risk of bias
Critically low confidence Critical risk of bias n/a
2.5 Data Synthesis … treatment; RA: rheumatoid arthritis;
RCT: randomized controlled trial; RF: rheumatoid factor; RR: relative … of bias
RR Relative risk
SDAI Simple disease activity index
SLE Systemic lupus erythematosus
SLEDAI … Patients With RA
Risk of
Bias
Domain
D1
Risk of
Bias
Domain
D2
Risk of
Bias
Domain
D3 … Risk of
Bias
Domain
D4
Risk of
Bias
Domain
D5
Risk of
Bias
Domain
D6
Risk of
Bias
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/machine-learning-tools-appendix-d.xlsx
January 01, 2024 - of bias assessment in RCTs can be supportive in some risk of bias domains. … ChatGPT for assessing risk of bias of randomized trials using the RoB 2.0 tool: A methods study 2023 … ChatGPT is currently unable to reliably assess risk of bias of randomized trials. … ChatGPT for assessing risk of bias of randomized trials using the RoB 2.0 tool: A methods study 2023 … ChatGPT is currently unable to reliably assess risk of bias of randomized trials.