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Showing results for "risk".

  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_executive.pdf
    January 27, 2012 - whom acamprosate and oral naltrexone are not suitable or who prefer disulfiram and understand the relativerisks of taking the drug; and (3) to have specialist and competent staff administer pharmacological … Risk-of-Bias Assessment of Individual Studies To assess the risk of bias (internal validity) of studies … the risk of bias for each study. … between acamprosate and naltrexone, whereas the risks of headache and vomiting were higher for those
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/bladder-cancer-non-muscle-invasive_research-protocol.pdf
    July 21, 2014 - number of available tests and testing strategies and potential trade- offs in diagnostic accuracy, risks … groups, may be especially useful for patients in the intermediate and high risk groups. … of bias,” “medium risk of bias,” or “high risk of bias.”15, 17 Studies rated “low risk of bias” will … We will not exclude studies rated as being high risk of bias a priori, but high risk of bias studies … Each study evaluated will be independently reviewed for risk of bias by two team members.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-prevention_executive.pdf
    May 01, 2013 - level as determined by different risk- assessment methods and/or by particular risk factors? … Increased Risk Low Risk Incidence of Pressure Ulcer Severity of Pressure Ulcer Harms 1 3 2 … When reported, we also extracted relative measures of risk (relative risk [RR], odds ratio, and hazards … Despite insufficient evidence to determine whether use of risk-assessment instruments reduces risk … Decisions about whether to use risk-assessment instruments and which risk-assessment instrument to
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-appendix-e.xlsx
    July 15, 2025 - Risk of bias of RCTs Author, Year Is randomization adequate? … Yes/No/Unclear Risk of Bias Low/Moderate/High Hajian, 2020 Yes (cluster) Yes (cluster) Yes No Unclear … Risk of bias of cohort studies Author, Year Did the study attempt to enroll all (or a random sample … Yes/No/Unclear Risk of Bias Low/Moderate/High Callahan, 2021 Unclear Yes Yes Unclear Unclear Yes Unclear
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
    November 22, 2011 - adequately precise o Studies that report or allow for the calculation of sensitivity or specificity, relative … comparative effectiveness with adequate precision o Studies that report or allow for the calculation of relative … , specificity, measures of variability), metrics of predictive ability (sensitivity, specificity, relative … performance 40 ) and relative-risk metrics (e.g., odds ratios or hazard ratios comparing outcomes … risk metrics (odds ratios, risk rations, hazard ratios) for clinical outcomes, will be undertaken
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_executive.pdf
    April 01, 2013 - Risk-of-Bias Assessment of Individual Studies To assess the risk of bias (internal validity) of studies … fluoxetine, paroxetine, and sertraline—most of the evidence was insufficient to determine whether risks … Findings were insufficient to determine whether the risks of other adverse events are increased. … approaches are more effective for victims of particular types of trauma or to determine comparative risks … The psychological risks of Vietnam for U.S. veterans: a revisit with new data and methods.
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_executive.pdf
    April 01, 2013 - profile among adults with SMI at elevated risk of CVD. … factors in adults with SMI who have elevated risk for CVD. … indices (e.g., Framingham Risk Score). … These guidelines for the general population should then be modified to consider the special risks for … or cardiovascular events Insufficient information Risk indices (e.g., Framingham Risk Score) and
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-260-improved-cancer-outcomes-executive-summary_0.pdf
    May 01, 2023 - nutrition support in gastrointestinal and head and neck cancers, 11 percent (n=12) were rated as low risk … of bias (higher quality), 40 percent (n=46) medium risk of bias and 49 percent (n=56) as high risk of … • Low- and medium-risk-of-bias studies reported mixed results on the effect of nutrition interventions … malnutrition is high among adults with cancer,5-7 but only 30 to 50 percent of cancer patients at risk … of bias (higher quality), 40 percent (n=46) medium risk of bias and 49 percent (n=56) high risk of
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement.pdf
    February 05, 2025 - to inform the implementation of interventions for children, adolescents, and young adults at high risk … Assessment of the Risk of Bias of Individual Studies We will evaluate the risk of bias of the included … of available studies (in a particular comparison) have high or unclear risk of bias. … How have the SSRI antidepressants affected suicide risk? … RoB 2: a revised tool for assessing risk of bias in randomised trials.
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/safety-vaccines-protocol.pdf
    January 30, 2020 - Also, what are the risks of specific adverse events, the frequency of events, and the certainty of the … frequency of potential side effects to help them weigh the benefits of vaccines against potential risks … We will calculate the relative risk for the adverse events for all studies by comparing the intervention … We will summarize the absolute rate of adverse events as well as the relative risk, to facilitate the … Risk analysis : an official publication of the Society for Risk Analysis. 2016;36(7):1297-314. doi:
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/people-with-disabilities-protocol.pdf
    January 16, 2024 - Assessment of Methodological Risk of Bias of Individual Studies Risk of bias (internal validity) is … Studies will be rated as “low risk of bias,” “medium risk of bias,” or “high risk of bias.” … Studies will be rated as “low risk of bias,” “medium risk of bias,” or “high risk of bias.” … Studies rated “low risk of bias” are considered to have the least risk of bias, and their results are … We will not exclude studies rated high risk of bias a priori, but high risk of bias studies will be
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
    August 01, 2012 - health outcomes) and KQ3 (adverse events), the conclusions are possibly out of date - Teratogenic risks … indicating that hypotension is an unusual side effect for oral antiepileptic drugs, whereas teratogenic risks … The expert emphasized that the large amount of new information on pregnancy outcome risks in women … , questioned the choice of side effects to review and thought it is inexcusable that teratogenic risks … specifying that it can cause fetal harm when administered to a pregnant woman, and the benefits and risks
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
    August 01, 2012 - health outcomes) and KQ3 (adverse events), the conclusions are possibly out of date - Teratogenic risks … indicating that hypotension is an unusual side effect for oral antiepileptic drugs, whereas teratogenic risks … The expert emphasized that the large amount of new information on pregnancy outcome risks in women … , questioned the choice of side effects to review and thought it is inexcusable that teratogenic risks … specifying that it can cause fetal harm when administered to a pregnant woman, and the benefits and risks
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0064_11-23-2008.pdf
    January 01, 2008 - 1 individual Nomination Summary: The anonymous nominator is interested in the comparative risks … What are the health risks and benefits of trabeculectomy as compared to alternatives, including laser … Does age modify this risk? From Nominator 2 (individual): 1.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research-protocol.pdf
    September 02, 2016 - this methodology report is to examine the feasibility and additional utility—in terms of impact on risk … For newly found studies, we will record additional data and assess their risk of bias. … We will apply the same risk of bias assessments as in the original review. … There is interest in comparative effectiveness of tympanostomy tubes in high-risk and at-risk populations … Many randomized trials are relatively small, limiting their ability to define risks of less common harms
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-youth-disposition-comments.pdf
    April 10, 2025 - One could argue there are other risk factors like depression. … It could be important to put 0, unknown, etc. as this is a high-risk sample. … more than the patient by reassuring the clinician and may reduce the visit time to focus on other risks … A majority of the studies rated high risk of bias, a few rated moderate risk, but no studies rated … as low risk.
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-2.pdf
    June 01, 2022 - Low risk Moderate risk Low risk Low risk Moderate risk Gur, 20212 Moderate risk Moderate risk Low … risk Low risk Low risk Low risk Yuan, 20213 Moderate risk Moderate risk Low risk Low risk Moderate risk … 4.74; I² =N/A Abbreviations: CI = confidence interval; mg = milligram; N/A = not applicable; RR = relative … 19.51; I² =N/A Abbreviations: CI = confidence interval; mg = milligram; N/A = not applicable; RR = relativerisk
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_executive.pdf
    February 01, 2012 - Ewing’s sarcoma family of tumors, and high-risk relapsed Wilm’s tumor. … The four required domains—risk of bias, consistency, directness, and precision—were considered for … The decision to apply a high-risk procedure such as HSCT to this population is not clear cut. … conditions addressed in this systematic review, evidence is insufficient to draw conclusions as to the relativerisk-benefit ratio of HSCT versus other management approaches.
  19. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/postpartum-care-one-year-protocol-amendment.pdf
    April 25, 2022 - parenthood, and consider future family planning, but also to mitigate immediate and lifelong health risks … planning and contraception o Adverse pregnancy outcomes associated with cardiometabolic disease o Risks … Assessment of Methodological Risk of Bias of Individual Studies: We will evaluate each study for risk … The three tools will include the Cochrane Risk of Bias Tool,20 the Risk of Bias in Nonrandomized Studies … Severe Maternal Morbidity and Risk of Mortality Beyond the Postpartum Period.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/bereaved-persons-research-executive-summ.pdf
    March 01, 2025 - • A small body of evidence has addressed the identification of bereaved people at risk or with grief … How accurate are tools to identify bereaved persons at risk for or with grief disorders? … What are the effectiveness, comparative effectiveness, and harms of interventions for people at risk … We assessed the risk of bias, evaluated the applicability of studies, and determined the SoE following … Abbreviations: CI = 95% confidence interval; N/A = not applicable, not available, no studies; RR = relative

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