-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - (Low)
RCTs of early RA treatment
showed no difference in risk of
serious infection or risk of
malignancy … Biologics neither decreased nor increased
cardiovascular risks in the elderly. … Risk did not differ
significantly by
specific drug. … MTX not
associated with
reduced risk. … Biologics neither decreased nor increased
cardiovascular risks in the elderly.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/Appendix%20F_0.xlsx
May 29, 2025 - Risk of bias of cannabis RCTs
Author, Year Randomization Adequate? … Risk of bias of cannabis RCTs
Table F-2. ROB Cohort Studies
Table F-2. … Risk of bias of cannabis cohort studies
Author, Year Did the Study Attempt to Enroll All (or a Random … Risk of Bias
Bestard, 2011 Yes Yes Yes No Yes Yes/No No Yes Moderate
Campbell, 2018 Yes Unclear Yes … Risk of bias of cannabis cohort studies
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-protein-intake-protocol-amendment.pdf
November 28, 2023 - Assessment of Methodological Risk of Bias of Individual Studies
Risk of bias of eligible randomized … controlled trials (RCTs) by outcomes will be
rated using the Cochrane Risk of Bias tool 2.0.21 Risk … For RCTs, the
overall risk of bias assessments for each study outcome will be classified as low risk … ,
moderate risk, or high risk. … of Bias
RR Risk Ratios
RD Absolute Risk Differences
RDA Recommended Dietary Allowance
SMD
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_executive.pdf
July 01, 2009 - changed over time, the
presence of sinus rhythm was associated with a
considerable reduction in the risk … therapy)
had a higher chance of maintaining sinus rhythm than
those treated with medical therapy alone (relative … risk
(RR) 3.46, 95-percent confidence interval (CI) 1.97-
6.09) at 12 months postprocedure. … found statistically
significant higher rates of recurrence in patients with
nonparoxysmal AF, with relative … risks of about 1.6.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_executive.pdf
June 01, 2012 - decisionmaking about treatment
options, and affect clinical outcomes, and (4) the safety
concerns and risks … Are there significant safety concerns/risks (i.e.,
radiation exposure, access site complications, contrast … ), the extant literature does not provide sufficient evidence
to conclude whether safety concerns, risks … information regarding decisionmaking, and few reported
the significant risks in women. … Finally, our
summary of the harms and risks of NITs is limited by the
lack of disclosure of periprocedural
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-urinary-retention_research.pdf
September 01, 2014 - Intent
To
Treat
Groups
Similar at
Baseline
Other
Risks
of Bias
Overall Risk of
Bias … group
(19/29) no longer needed catheterization compared to the delayed implant group (2/22) with a
relative … Insufficient
PVR (ml), adjusted MD -135 [95%CI -233 to -37] Moderate Indirect Precise Single study Low
RR = relative … 1068 [95% CI --1493to -643 ] Moderate Indirect Precise Single study Low
SR=systematic review; RR = relative … 95% CI -47 to 0.63] Moderate Indirect Precise Single study Low
Single study = not applicable; RR = relative
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-diagnosis-future_research.pdf
February 01, 2012 - stakeholders’ discussions
centered on the anecdotal nature of the evidence regarding perioperative risks … Most of the discussion centered on the anecdotal nature of the evidence regarding the
perioperative risks … The effectiveness of perioperative care was discussed as well as
strategies for mitigating risks such … We set the range of relative risk reduction between 0.6 and 0.8, as the study
reported a relative risk … power of 90 percent,
the required total sample size (1:1 ratio in a two-arm RCT) for each value of relative
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-app-g-table-surveillance-report-2_0.xlsx
May 29, 2025 - Risk of bias of cannabis RCTs
Author, Year Randomization Adequate? … Risk of bias of cannabis RCTs
Table G-2. ROB Cohort Studies
Table G-2. … Risk of bias of cannabis cohort studies
Author, Year Did the Study Attempt To Enroll All (or a Random … Risk of Bias
Bestard, 2011 Yes Yes Yes No Yes Yes/No No Yes Moderate
Campbell, 2018 Yes Unclear Yes … Risk of bias of cannabis cohort studies
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis_research-protocol.pdf
June 06, 2011 - Coronary angiography is generally indicated in patients who have chest pain and are
at high risk for … For intermediate-risk patients, clinicians have a wide range of
noninvasive diagnostic modalities to … Risk stratification/prognostic information?
b. … KQ 4: Are there significant safety concerns/risks (i.e., radiation exposure, access
site complications … of life in the population of interest) (KQ
3); and whether there are significant safety concerns or risks
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_9-user-guide-to-ocer_130129.pdf
September 21, 2012 - Effect of
Interest
Therapy 1
Risk
Therapy 2
Risk
Desired
Power
Needed
Study Size
Needed
Recruitment … The effect of interest is specified as a risk ratio. … (10.54
percent), a clinically important excess risk. … For example, database studies
may identify small excess risks of about 5 percent
that would fall below … Risk of
death in elderly users of conventional vs. atypical
antipsychotic medications.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-active-infection-rapid-response.pdf
May 01, 2024 - Four studies were assessed to be at moderate risk of bias,
one study was at low risk, and one study … was at serious risk. … Both studies were assessed to have a moderate risk of bias. … This study was at
moderate risk of bias. … screening was a “norm,” with little information provided to them about the
purpose of surveillance or the risks
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0129_07-13-2009.pdf
January 01, 2009 - 10
1
Results of Topic Selection Process & Next Steps
Cesarean birth in low-risk … The nominator is interested in which factors influence the probability of
cesarean birth in low-risk … women and which interventions are most effective at reducing
the risk of emergency and/or medically … Which interventions are most effective at reducing the risk of needing an emergency
and/or medically … Some of the
Healthy People 2010 objectives focus on reducing cesarean births among low-risk women.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_research-protocol.pdf
October 01, 2013 - or both), duration, and type of intravascular fluids used to
prevent CIN15; and d) the comparative risks … The IA route may confer more risk than the IV use,5, 20, 21 but that risk may
be confounded by the pre-existing … This emphasizes the
need for a comprehensive evidence-based synthesis of risks for patients undergoing … ● High or moderate risk patients (as defined by clinical or demographic risk
factors such as age … Assessment of Methodological Risk of Bias of Individual Studies – The
assessment of risk of bias will
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
November 22, 2011 - adequately precise
o Studies that report or allow for the calculation of sensitivity or specificity,
relative … comparative effectiveness with adequate precision
o Studies that report or allow for the calculation of relative … , specificity, measures of variability),
metrics of predictive ability (sensitivity, specificity, relative … performance
40
) and relative-risk metrics (e.g., odds ratios or hazard ratios comparing
outcomes … risk metrics (odds ratios, risk rations, hazard
ratios) for clinical outcomes, will be undertaken
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-264-maternal-morbidity-mortality-disposition-comments.pdf
December 21, 2023 - Our focus was on risk factors
for maternal health. … others to
engage sharing knowledge and letting others share there feed back and voice The
less the risks … Several
studies looked at the protective and risk factors together. … somewhat connected with efforts to consolidate resources and
experience, we have become more aware of the risks … Public
Commenter
#11
Tammy Hall
Discussion The risk is major Thank you for the comment.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_executive.pdf
January 27, 2012 - whom acamprosate and oral naltrexone are not suitable
or who prefer disulfiram and understand the relative … risks
of taking the drug; and (3) to have specialist and competent
staff administer pharmacological … Risk-of-Bias Assessment of Individual Studies
To assess the risk of bias (internal validity) of studies … the risk of bias for
each study. … between acamprosate and naltrexone, whereas the risks
of headache and vomiting were higher for those
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-risk-bias.ppt
June 01, 2012 - Assessing risk of bias as a domain of quality in medical test studies. … Assessing risk of bias as a domain of quality in medical test studies. … Assessing risk of bias as a domain of quality in medical test studies. … Assessing risk of bias as a domain of quality in medical test studies. … (Risk: Low/High/Unclear)
QUADAS-2 Questions for Assessing Risk
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-risk-bias.ppt
June 01, 2012 - Assessing risk of bias as a domain of quality in medical test studies. … Assessing risk of bias as a domain of quality in medical test studies. … Assessing risk of bias as a domain of quality in medical test studies. … Assessing risk of bias as a domain of quality in medical test studies. … (Risk: Low/High/Unclear)
QUADAS-2 Questions for Assessing Risk
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible.pdf
January 01, 2021 - accumulation that presents a risk to health. … Assessment of the Risk of Bias of Individual Studies
We will evaluate the risk of bias of the included … unclear risk of bias studies and not rate down the SOE. … Diet, lifestyle, and the risk of type 2 diabetes
mellitus in women. … RoB 2: a revised tool for assessing risk of bias in
randomised trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-disease-medicine_research-protocol.pdf
November 01, 2010 - and burden is decreased by competing risks such as
short life expectancy. … Studies will be rated as Good (low
risk of bias), Fair, or Poor (high risk of bias) as described in … Chronic kidney disease and
the risks of death, cardiovascular events, and hospitalization. … Renal function and risk of hip and vertebral fractures in older women. … CKD
and risk of hospitalization and death with pneumonia.