-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-prognostic.ppt
June 01, 2012 - not experience the outcome of interest
Statistically significant associations (odds/hazard ratios, relative … risks) merely indicate that more definitive evaluation of a new predictor is warranted. … Statistically significant associations such as HRs, relative risk, or ORs ratios indicate only that it … Assessing the value of risk predictions by using risk stratification tables. … Assessing the value of risk predictions by using risk stratification tables.
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-prognostic.ppt
June 01, 2012 - not experience the outcome of interest
Statistically significant associations (odds/hazard ratios, relative … risks) merely indicate that more definitive evaluation of a new predictor is warranted. … Statistically significant associations such as HRs, relative risk, or ORs ratios indicate only that it … Assessing the value of risk predictions by using risk stratification tables. … Assessing the value of risk predictions by using risk stratification tables.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_research-protocol.pdf
April 01, 2013 - reduction in prostate cancer mortality, a relative risk reduction of 44
Source: http://effectivehealthcare.ahrq.gov … Institutes of Health (NIH) State-of-the Science Conference in December 2011 to better
understand the risks … The KQs we will address are as
follows:
Key Question 1
What are the comparative risks and benefits … of bias, the study neither meets the criteria
for low risk of bias nor the criteria for high risk of … to establish study risk of bias.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/masks-prevention-covid-surveillance-report.pdf
July 17, 2020 - of
SARS-CoV-2
infection
Insufficient evidence to
determine effects of masks on
risk of SARS-CoV … in moderate or
higher risk settings. … in lower risk
(outpatient) settings. … One new observational study1 on mask use and risk of SARS-CoV-2
infection in community settings was … There was no association between mask use after illness onset in the index case
and risk of SARS-CoV
-
effectivehealthcare.ahrq.gov/sites/default/files/prostate-cancer-therapies-summary.pdf
September 01, 2020 - Effects may not vary by patient or tumor risk factors. … Results may not vary
by patient or tumor risk characteristics. … Retrospective observational
studies often had a high risk of bias. … Age and tumor risk category may be important effect modifiers. … reduction
due to RP may be limited to intermediate-risk disease or age <65 years.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-executive-summary-2023-update.pdf
January 01, 2023 - There may be a large increased
risk of dizziness and sedation and a moderate increased risk of nausea … of sedation, and potential increased risk of
nausea versus placebo. … Synthetic THC is probably associated with a large
increased risk of dizziness. … -point scale
• SMD >0.8
• RR/OR ≥2.0
Abbreviations: MD = mean difference; OR = odds ratio; RR = relative … risk; SMD = standardized mean difference.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-263-postpartum-hypertensive-pregnancy-executive-summary.pdf
May 01, 2023 - regimens
o Lower-dose MgSO4 regimens, compared with standard dose regimens:
May increase the risk … We assessed the risk of bias and
evaluated the SoE using standard methods. … difference in the rate of initiation of antihypertensive medications
(reported adjusted odds ratio [OR] and relative … risk [RR] = 1.0; other measures of BP
management were sparsely reported). … of recurrent seizures (Moderate SoE) but not the risk of death
(Low SoE).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-monitoring-systems-rapid-review.pdf
December 01, 2024 - They found that the relative risk of a major adverse event
was statistically lower (p<0.001) in the … Australian Between the Flags system) and
found no significant change in response to the intervention (relative … of death 30 days post-alert was significantly reduced
(relative risk 0.84, 95% CI 0.78 to 0.90, p<0.001 … increase in transfers (p=0.00154 and p=0.0356), two reported
statistically significant decreases (relative … assessment”[tiab] OR
“risk assessment”[mh] OR “risk classification”[tiab] OR “risk category”[tiab]
-
effectivehealthcare.ahrq.gov/sites/default/files/mccullough.pdf
January 01, 2011 - and inadequate risk assessment in
reaching judgments
about medical reasonableness, the physician … should assume that these risks are
clinically significant. … disapproval,
discourage, but do not abandon
the patient
When evidence level
for judgment of
risk … the benefit
of doing so
Relieved of the burden of decision making
o Informed about
the risk … engage in
scientifically sophisticated moral management
of medical uncertainty
o First-‐trimester risk
-
effectivehealthcare.ahrq.gov/sites/default/files/coronary-artery-disease-testing_disposition-comments.pdf
March 29, 2016 - Reviewer 2 Methods Analyses was performed in subgroups of patients stratified
by different pre-test risks … But only the pre-test risks reported by authors
of the studies were used for stratification. … The review team spent substantial time
considering ways of standardizing the
findings on pre-test risks … is harm in itself
if not associated with demonstrable clinical benefit as these
entail real, known risks … (unlike radiation in which the risks are
theoretical and not known).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-surgical-report-cards.pdf
November 01, 2023 - The
National Veterans Administration Surgical
Risk Study: risk adjustment for the
comparative assessment … Using risk-adjusted outcomes to
assess clinical practice: an overview of
issues pertaining to risk adjustment … The National Veterans Administration Surgical Risk
Study: risk adjustment for the comparative assessment … 30-day mortality (relative risk
[RR] 0.96, 95% CI, 0.89–
1.03), serious complications
(RR 0.96, 95% … Data Bank; O/E = observed vs expected ratio; PDSA = Plan Do Study Act; PE = pulmonary embolism; RR = relative
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-217-infertility-evidence-summary.pdf
May 01, 2019 - Different treatments also carry different safety
risks. … There are known short-term risks such as
ovarian hyperstimulation syndrome (OHSS) or
acute risks associated … Surgery
may have additional longer-term risks which may
affect subsequent fertility (such as scarring … of these
procedures, with no evidence on potential longer
term risks. … Risks of adverse
longer term maternal cancer outcomes were
generally not increased after adjustment
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_clinician.pdf
March 01, 2016 - antibiotic prescribing (and, in
some cases, improve appropriate prescribing) without
increasing the risk … associated with an increased number of days
with moderately severe symptoms and possibly increased
risk … infection; OR = odds ratio;
PCR = polymerase chain reaction; RCT = randomized controlled trial; RR = relative … risk; RTI = respiratory tract infection; SOE = strength of evidence;
SR = systematic review; URTI … AOM = acute otitis media; CI = confidence interval; RCT = randomized controlled trial; RR = relative
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/masks-surveillance-2-report.pdf
October 01, 2020 - MERS-
CoV
Community settings: Masks
(type not specified) are possibly
associated with decreased risk … in moderate or
higher risk settings. … versus cloth
masks in moderate or higher
risk settings. … in lower risk
(outpatient) settings. … One new observational study1 on mask use and
versus no use risk of SARS-CoV-2 infection in healthcare
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_executive.pdf
September 01, 2009 - from medications to
reduce risk of breast cancer? … Raloxifene does not increase risk
for cataracts or cataract surgery. … Clinical risk assessment models to
identify women who could benefit from medications
to reduce risk of … breast cancer:
• Nine risk stratification models that predict an
individual’s risk for developing breast … Models
consider multiple risk factors for breast cancer.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_surveillance.pdf
July 01, 2012 - Pfizer NOT
pursuing FDA approval) has
come out that shows that a
0.5 mg dose appears to
reduce the risks … from medications to
reduce risk of breast cancer? … Nine risk
stratification
models that
predict an
individual’s risk
for developing
breast cancer … Incidence
rates/risks of
gynecologic
conditions
Median 81
month follow-
up reported
Good/Good … Nine risk stratification models that
predict an individual’s risk for
developing breast cancer have
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/fatty-acids-cardiovascular-disease_research-protocol.pdf
April 02, 2015 - For RCTs, we will use the Cochrane risk of bias tool (38), which asks about risk
of selection bias, … levels of intake), d) account for the
grouping of data by study, and e) allow for different baseline risks … Report of the Joint FAO/WHO Expert Consultation on the Risks and Benefits of Fish
Consumption. … Institute of Medicine, Committee on Nutrient Relationships in Seafood: Selections to Balance Benefits
and Risks … Seafood Choices; Balancing Benefits and Risks.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol-amended.pdf
February 07, 2025 - We will assess the risk of bias for
RCTs using the Cochrane Risk of Bias 2 (ROB2) and NRSIs (including … As different outcomes and results from the same study may reflect different risks of
bias (e.g., objective … yields a higher SOE rating
than a set of studies at moderate or high risk of bias. … of
bias is comparable to an RCT at low risk of bias. … RoB 2: a revised tool for assessing risk of bias in
randomised trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_executive.pdf
November 01, 2013 - Assessment of Risk of Bias
To assess the risk of bias for individual studies, we
followed the methods … Added Value of BNP to Prognostic Risk Prediction. … Relative
risks, confidence intervals, and SOE are presented in Table
B. … heart failure IMprove heart fAilure morbidity and mortality;
RCT = randomized controlled trial; RR = relative … and any other established risk
markers.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19.pdf
December 31, 2022 - risk of infection in people
who have never been infected? … Impact of Omicron and Delta variants on risk of
reinfection. … Overall, the relative
risk of infection was 0.16 (95% CI: 0.14, 0.18) for seropositive individuals versus … risk of infection in people who have never been infected? … Comparative analysis of the risks of
hospitalisation and death associated with SARS-
CoV-2 omicron (