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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_disposition-comments.pdf
    September 01, 2014 - Therapeutic decision-making involves assessment of the trade-offs between potential risks and potential … If the potential risks are not defined, then the decision-maker in not sufficiently well informed to … on CV risk score and those that treat just based on LDL. … set up to fail—there are no trials to adequately answer the question about long term benefits and risks … Change to: “among patients at high and moderate CHD risk, defined as a 10-year CHD risk greater than
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/urinary-incontinence-treatment_research-protocol.pdf
    September 30, 2010 - hypotheses and did not provide adequate information on tested hypotheses (e.g., least square means, relativerisk); 2. … risk, and absolute risk differences (ARD). … Poor (high risk of bias). … We will calculate relative risk and absolute risk difference from the abstracted events using Meta-analyst91
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_executive.pdf
    January 01, 2015 - Quality (Risk-of-Bias) Assessment of Individual Studies The risk of bias of eligible studies was assessed … For RCTs we assessed the risk of bias using a modified Cochrane risk-of-bias tool.42 We used additional … risk of bias … All assessed unique outcomes in disparate subgroups and all had high risk of bias. … In assessing risk of bias, we assessed typical risk-of-bias domains for RCTs and added subgroup questions
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation_executive.pdf
    June 01, 2012 - Risk of Bias Assessment of Individual Studies Risk of bias assessment forms were developed specifically … For RCTs, we modified the Cochrane Risk of Bias Tool26 by adding items to capture potential risk of … Investigators consulted to reconcile discrepancies in overall risk of bias assessments. … Of these eight studies, one was rated low risk of bias, and seven were rated moderate risk of bias. … Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S, eds.
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer_research-protocol.pdf
    July 24, 2013 - Institute’s Surveillance, Epidemiology, and End Results Cancer Statistics Review found that the lifetime risk … The population of high-risk patients is defined, as per the AASLD clinical guidelines, as composed … o Key Question 2  Patients at high risk for HCC in whom a suspicious lesion(s) has been detected … Each study evaluated will be dual reviewed for risk of bias by two team members. … Other definitions of high risk patients as defined by the primary studies will be accepted.
  6. effectivehealthcare.ahrq.gov/health-topics/vaginitis
  7. effectivehealthcare.ahrq.gov/health-topics/healthy-sleep
  8. effectivehealthcare.ahrq.gov/health-topics/lupus
  9. effectivehealthcare.ahrq.gov/health-topics/diarrhea
  10. effectivehealthcare.ahrq.gov/health-topics/mosquito-bites
  11. effectivehealthcare.ahrq.gov/health-topics/fatty-liver-disease

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