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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ocr-protocol-final_1.pdf
    December 18, 2019 - more satisfying IOL, while reducing inpatient length of stay compared to inpatient CR. 2 The risks … However, there are concerns regarding potential risks of outpatient CR to the woman and fetus in comparison … The risks of CR may be mitigated through the choice of CR method and clinical management. … Careful review of existing literature is needed to elucidate whether these risks occur more frequently … versus inpatient setting and whether maternal or fetal characteristics differentially affect these risks
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-prognostic_methods.pdf
    July 01, 2012 - the means are highly significantly different.16,17 Statistically significant associations (hazard, relative … interested in these associations, there are well established methods for summarizing estimates of hazard, relative … group and 25 percent of the 400 people in the higher risk group. … ” and “don’t treat those at low risk.” … Assessing the value of risk predictions by using risk stratification tables.
  3. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
    February 01, 2012 - Do the effectiveness and risks of FGAs and SGAs vary in differing subpopulations including: • Sex? … The two NRCTs had a high risk of bias. … prospective cohort study; RCS = retrospective cohort study; RCT = randomized controlled trial; RR = relative … first-generation antipsychotic; PCS = prospective cohort study; RCT = randomized controlled trial; RR = relative … Treatment benefits and risks were examined most frequently for schizophrenia; the evidence for conditions
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-therapies-update_disposition-comments.pdf
    December 16, 2014 - Effect of age, tumor risk, and comorbidity on competing risks for survival in a US population-based … study suggests that PC death in the PIVOT study was diluted by deaths from other causes or competing risks … For example, KQ1 is: “What are the comparative risks and benefits of the following therapies for clinically … surveillance or watchful waiting – these could be considered separate if desired) What are the comparative risks … Effect of age, tumor risk, and comorbidity on competing risks for survival in a U.S.
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-high-risk-drugs-rapid-response.pdf
    January 01, 2024 - medications help prevent life-threatening events such as pulmonary embolism, but they also increase the risks … concern is the transition to home, where the patient and/or caregiver must be aware of the purposes and risks … Other risks of anticoagulant use include liver injury,17 minor bleeding,18 and dermatologic effects.19 … These risks underscore the importance of managing patients through care transitions and in the ambulatory … factors, thereby reducing risks of adverse events beyond what anticoagulation management alone can
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-health-mobile-apps-disposition-of-comments.pdf
    May 20, 2022 - We agree that the risk of the app should stand separately, and it does in the framework. … prevent individuals from benefitting from app use, but we do want to provide an assessment of the risks … Currently, only Section 1 “Risk and Mitigation Strategies” is scored. … This places patients and providers at risk by technology companies. … We also support AHRQ’s approach with respect to risk and the requirement for evidence and, for high-risk
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-3.pdf
    August 01, 2022 - hours, the combined treatment group reported significantly more patients with improved function (RR [relative … nonsteroidal anti-inflammatory drug; QoL = quality of life; RCT = randomized clinical trial; RR = relative … Low risk Low risk Low risk Hodgson, 20219 Low risk Low risk Low risk Low risk Low risk Low risk … Low risk Moderate risk Low risk Lipton, 202112 Low risk Low risk Low risk Low risk Low risk Low riskrisk Low risk Low risk Low risk Sakai, 202116 Low risk Low risk Low risk Low risk Low risk Low risk
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-function_research-protocol.pdf
    June 13, 2013 - This may subject patients to unnecessary coronary angiography and its potential risks (i.e., contrast … using traditional risk factors such as the Framingham Risk Score. … using traditional risk factors such as the Framingham Risk Score. … • Poor (high risk of bias). … DerSimonian and Laird formula.30 For dichotomous outcomes, we will calculate a pooled effect estimate of the relative
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-evidence-summary-2022-update_0.pdf
    January 01, 2022 - There may be a large increased risk of dizziness and sedation and a moderate increased risk of nausea … of sedation, and potential increased risk of nausea versus placebo. … Synthetic THC is probably associated with a large increased risk of dizziness. … -point scale • SMD >0.8 • RR/OR ≥2.0 Abbreviations: MD = mean difference; OR = odds ratio; RR = relativerisk; SMD = standardized mean difference.
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/mrsa-screening_research.pdf
    June 01, 2013 - attempt to measure the favorable impact of screening for MRSA-carriage while ignoring its potential risks … Knowledge about risk factors can be used to identify high risk populations suitable as target groups … Patients with these risk factors, especially mutable risk factors, may then be targeted for prevention … of study design for producing a valid result Prospective cohort studies permit calculation of relative … Permits estimation of relative risk through an odds ratio.
  11. effectivehealthcare.ahrq.gov/sites/default/files/coronary-artery-disease-testing_executive.pdf
    March 01, 2011 - (ACS), although its invasive nature makes it less ideal in many patients because of its associated risks … harms, adverse reactions to drugs for stress tests, vascular complications (e.g., stroke) Consequences/risks … related to harms of testing (e.g., adverse reaction or allergy to contrast or stress agents) and risks … high risk, and mixed risk (or pretest risk not reported). … In addition, potential harm from use of invasive treatments (which carry specific risks) if clinical
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-protocol.pdf
    April 08, 2024 - Reported risks to the pregnant person include gestational diabetes, hypertension, cesarean section, … and post-partum weight retention.18-20 Risks to the developing fetus include larger birth size (macrosomia … ), higher body fat percentage at birth, preterm delivery, and impaired glucose tolerance.21-26 Risks … Assessment of Risk of Bias for Individual Studies We will use predefined criteria to assess the risk … Assessing risk of bias in a randomized trial.
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-apps-a-e-surveillance-report-2-final_0_0.pdf
    March 01, 2022 - There may be a large increased risk of dizziness and sedation, and a moderate increased risk of nausea … -point scale • SMD >0.8 • RR/OR ≥2.0 Abbreviations: MD = mean difference; OR = odds ratio; RR = relative … confidence interval; KQ = Key Question; MD = mean difference; RCT = randomized controlled trial; RR = relative … ; KQ = Key Question; MD = mean difference; OR = odds ratio; RCT = randomized controlled trial; RR = relative … General risks of harm with cannabinoids, cannabis, and cannabis-based medicine possibly relevant to
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-disposition.pdf
    June 22, 2017 - have added low strength of evidence findings regarding LMWH vs. aspirin in THR patients (similar risks … However, the relative risks of surgical site bleeding are 6.38 (95% CI 4.56-8.92) for LMWH vs ASA, … from LMWHs to FXaIs and found a significant increase in total wound complications (LMWH vs FXaI relative … Therefore, FXaIs have a higher risk of wound complications than LMWH and LMWHs have the highest relative … increase the risk of a VTE event to a level that the risks of surgical site bleeding and death are
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/dietary-supplements_research-protocol.pdf
    December 15, 2010 - Nomination: The original nomination for this review was for a comparative effectiveness review of the risks … scarce data in this subgroup, the topic for this review was broadened to address the benefits and risks … the United States, which includes dietary supplementation, a request to evaluate the benefits and risksrisk, and absolute risk differences (ARD). … For observational studies, we will extract crude rates or relative measures of the association (relative
  16. effectivehealthcare.ahrq.gov/sites/default/files/ch-7-user-guide-to-ocer_130129.pdf
    March 29, 2012 - Causal graph illustrating a baseline risk factor (C 0 ) for the outcome (Y 1 ). … pressure after treatment is initiated (C 1 ), is unnecessary and is likely to induce bias2 toward a relativerisk of 1.0, though the direction can sometimes be in the opposite direction. … A deep understanding of the specific clinical and public health risks and opportunities that lie behind … Confounding by indication and channeling over time: the risks of beta 2-agonists.
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_executive.pdf
    November 01, 2012 - The strongest risk factor for HCV infection is injection drug use. … While antiviral therapies are contraindicated in pregnancy due to teratogenic risks, identification … factors miss a substantial proportion of infected patients, in part due to undisclosed or unknown risks … Description of a new hepatitis C risk assessment tool. … The incidence and risks of liver biopsy in non-cirrhotic patients: An evaluation of 3806 biopsies.
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_executive.pdf
    March 01, 2013 - irregular bleeding.81 COCs Primary care providers and many women are aware of the most serious risks … included over 38,000 person- years of contraceptive vaginal ring use reported an elevated adjusted relative … These agents include a boxed warning on the product labels about cardiovascular and GI risks.104-106 … found in the Food and Drug Administration sources discussed in the main document and do not have risks … Thrombotic risks of oral contraceptives. Curr Opin Obstet Gynecol 2012 Aug;24(4):235-40.
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
    September 01, 2014 - of cancer, or did not provide information on baseline risk. … Assessment of Risk of Bias We assessed the risk of bias for each individual study following the Methods … Results are based on the model with risk group as a covariate. … of vasovagal reactions; however, results were reported in a way that precluded quantitation of the relativerisk.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-disposition-120516.pdf
    October 01, 2011 - Age: You make important points about absolute vs. relative risk. … sentence in question in the Executive Summary is referring to the finding in meta-analysis that the relative … clear association between longer duration of therapy with COX-2 selective NSAIDs and increase in the relative … Regarding differential risks in older patients, as noted in the Results (page 83, starting line 50): … what the review covers, major new evidence covered in the review, and the unique trade-offs between risks

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