-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - • In THR, LMWH has lower VTE and
adverse event risks than unfractionated
heparin; LMWH and aspirin … have
similar risks of VTE and major
bleeding; direct thrombin inhibitors
(DTI) have lower DVT risk … SoE), but similar risks for total VTE (moderate SoE)
and symptomatic DVT (low SoE); risk of major … VKA: There is a tradeoff in risks
between the two drug classes, such that LMWH
better lowers risk of … SoE),
but similar risks for symptomatic DVT (low SoE); risk
of major bleeding is lower with LMWH (
-
effectivehealthcare.ahrq.gov/sites/default/files/thromboembolism-update-executive-170622.pdf
June 01, 2017 - • In THR, LMWH has lower VTE and
adverse event risks than unfractionated
heparin; LMWH and aspirin … have
similar risks of VTE and major
bleeding; direct thrombin inhibitors
(DTI) have lower DVT risk … SoE), but similar risks for total VTE (moderate SoE)
and symptomatic DVT (low SoE); risk of major … VKA: There is a tradeoff in risks
between the two drug classes, such that LMWH
better lowers risk of … SoE),
but similar risks for symptomatic DVT (low SoE); risk
of major bleeding is lower with LMWH (
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-adults-executive-130408.pdf
April 01, 2013 - Using Meta-Analyst and STATA® software, we calculated
the relative risk and absolute risk difference … We evaluated the
strength of the association, defining a priori a large effect
when relative risk was … >2 and a very large effect when
relative risk was >5.25 We defined low magnitude of the
effect when … relative risk was significant but <2. … Our review
demonstrated that a relative risk of adverse effects with
onabotulinumtoxin A was lower
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-245-breast-reconstruction-after-mastectomy-disposition-comments.pdf
October 01, 2021 - For example, the discussion of the risks of
reconstruction with breast implants barely mentions
breast … For
example, when discussing the risks of reconstruction
with breast implants, the draft only mentions … mention that when mastectomies are
unnecessary, choosing lumpectomy will make
reconstruction (with its risks … Research
Introduction The report barely mentions the autoimmune, connective
tissue, and neurological risks … It states “These risks of systemic
symptoms and BIA-ALCL led the U.S.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_executive.pdf
August 01, 2016 - It found significant associations between higher
plasma DPA and lower risks of all-cause and CVD death … ,
which included people who may have other nutrition
deficiencies that may affect chronic disease risks … or associations of higher n-3 FA intake or biomarker levels and
lower cardiovascular disease (CVD) risks … Report of the Joint FAO/WHO Expert Consultation on
the Risks and Benefits of Fish Consumption. … Seafood Choices: Balancing Benefits
and Risks. Nesheim MC, Yaktine AL, editors.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-242-radiation-therapy-brain-metastases-evidence-summary.pdf
June 01, 2021 - • Risk of bias varied, 25 RCTs were terminated early, predominantly due to poor
accrual. … WBRT plus systemic therapy was associated with increased risk for
vomiting. … Random effects meta-analyses computed
hazard ratios (HRs), relative risks (RRs), and standardized mean … Risk of bias varied, 25 trials were terminated
early and the quality of adverse assessment and reporting … to 3.44; 4 studies, low SoE).
6
WBRT plus systemic therapy showed an increased risk
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/febrile-infants-diagnosis-management_executive.pdf
March 01, 2012 - dilemma that practitioners
often face is how to avoid missing a case of
SBI versus how to avoid the risks … What is the evidence for the potential risks
resulting from a delay in the diagnosis and treatment … There is very little evidence on the risks of delayed
diagnosis and management of low-risk infants who … The group of low-risk patients needs to be defined by
incorporating risks associated with age group … Risks for
bacteremia and urinary tract infections in young febrile
children with bronchiolitis.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-protocol.pdf
April 17, 2024 - Assessment of Methodological Risk of Bias of Individual Studies: We define the risk of bias
as the risk … We will assess the risk of
bias for each included study using the Cochrane Risk of Bias 2 (ROB2) tool … category, and risk of bias rating. … >0.8
RR/OR/HR ≥2.0
Abbreviations: HR = hazard ratio; MD = mean difference; OR = odds ratio; RR = relative … risk; SMD = standardized mean difference.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/joint-replacement-evidence%20-summary.pdf
November 01, 2021 - o Prehabilitation prior to TKA may not increase the risk of harms (low SoE). … We assessed the risk of
bias and evaluated the SoE using standard methods. … Prehabilitation prior to TKA may not increase the risk
of harms (low SoE). … Post-acute rehabilitation may have comparable risks of harms among
various rehabilitation interventions … The included studies were mostly at moderate to
high risk of bias.
-
effectivehealthcare.ahrq.gov/sites/default/files/thompson_eccs2012.pdf
January 01, 2012 - Louis,
MO
Slide 2: Informed Decision Making
(1 of 2)
• Understands
the
nature
and risks …
• Understands
the
risks
and benefits
• Understands
alternatives
• Participates … .
o Presenting risk information increased perceived risk without
increasing
worry,
fear,
or … o How should risk information be presented? … .
o Include social math strategies.
o Graphically show risks/harms, as well as benefits (facts boxes
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_3-user-guide-to-ocer_130129.pdf
September 21, 2012 - For the relative risk model, u
i
=
log [prob(Y
i
(2)=1)] – log[prob(Y
i
(1)=1)]. … excluded from a randomized trial, but a treating
clinician may decide that the benefits outweigh the
risks … They used existing risk
models (Framingham and Reynolds risk scores), as
well as a prediction model … The average treatment effect (ATE) (relative risk)
was applied to calculate individual treatment
effects … Subgroup
analyses in randomised controlled trials:
quantifying the risks of false-positives and
false-negatives
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0251_05-20-2010.pdf
January 01, 2010 - Staff-Generated PICOS:
Population(s): Patients at risk of developing pressure ulcers and patients with … pressure
ulcers
Intervention(s): Identification of patients at risk for, prevention, and treatment … specialized mattresses,
undergarments, creams, and nursing routines
Outcome(s): For measures of risk … How can we identify patients at risk for pressure ulcers in the hospital or long-term
care setting … what is the evidence for the validity and reliability of various
instruments for estimating these risks
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
September 01, 2012 - spending in the United
States.4 The ultimate goal in preventing
preterm birth is to eliminate the risks … factors or cointerventions intended to further reduce
risk of preterm birth. … Lack of large-scale, systematic evidence about
potential risks of treatment is concerning to providers … of progestogen, to determine
whether long-term outcomes are improved, and to rule
out longer term risks … Progesterone and the risk of
preterm birth among women with a short cervix.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_disposition-comments.pdf
July 08, 2014 - Socioeconomic status may be an important modifying
factor, but does not argue against the risks associated … We agree that it is very important to understand the risks
of antidepressant treatment to pregnant and … postpartum
women and offspring, as well as the risks of depression to
pregnant and postpartum women … unclear whether the signal evidence from
this systematic review warrants singling out these three
risks … Added definition for RRR: relative risk reduction (reported in the
study rather than relative risk)
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ped-mindfulness-protocol-amended.pdf
September 25, 2024 - Assessment of Methodological Risk of Bias of Individual Studies: We define the risk of bias
as the risk … We will assess the risk of
bias for each included study using the Cochrane Risk of Bias 2 (ROB2) tool … 100-point scale
SMD >0.8
RR/OR ≥2.0
Abbreviations: MD = mean difference; OR = odds ratio; RR = relative … risk; SMD = standardized mean difference. … Strategies; PedsQL = Pediatric Quality of Life Inventory; RADS =
Reynolds Adolescent Depression Scale; RR = relative
-
effectivehealthcare.ahrq.gov/sites/default/files/Evidence%20Summary_2.pdf
May 01, 2020 - Abbreviations: CI=confidence interval; hr=hours; RCT=randomized controlled trial; RR=relative risk; SOE … confidence interval; EA=epidural analgesia; MD=mean difference: RCT=randomized controlled
trial; RR=relative … Abbreviations: CI=confidence interval; NICU=neonatal intensive care unit; RCT=randomized controlled trial;
RR=relative … Abbreviations: RCT=randomized controlled trial; RR=relative risk; SOE=strength of evidence; SR=systematic … Key
findings include:
• Valsalva/coached and spontaneous/uncoached
pushing have similar risks of trauma
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-257-antenatal-care-evidence-summary.pdf
June 01, 2022 - overcrowding (of
clinics), may increase clinic time available to be directed to patients
with high-risk … The RCTs were mostly at low risk of bias, except
that studies could not blind the intervention (one … The
survey was at low risk of bias. The number of televisits ranged from one to five. … increased risks (e.g., stressors). … The NRCSs were almost all unadjusted and thus subject to high
risk of bias.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/bereaved-persons-protocol.pdf
June 01, 2023 - pain, and feelings of bitterness.8, 9 In addition, recently bereaved
individuals face higher medical risks … follow-up was resource intensive and
difficult to implement.35 This gap between intervention and follow-up risks … For each domain, we will assess the potential risk of bias in the study in order to
identify high-risk … of bias and low risk of bias studies. … statistically, we will convert to measure-
independent effect estimates (standardized mean differences, relative
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-function_executive.pdf
August 01, 2014 - through December 2004, and found
17 studies evaluating troponin T for all-cause mortality
(pooled relative … They found 12 studies for troponin I for all-
cause mortality (pooled relative risk, 1.7; 95% confidence … individual studies
identified for troponin I were not statistically significant,
but their pooled relative … We were able to perform meta-analyses
for both HRs (time to event) and ORs (relative risk) as
available … , whereas Khan et al. only performed relative
risk analyses.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/outcomes-dental-services-rapid-research.pdf
May 01, 2025 - risk of bias. … risk of bias High risk of bias
Critically low confidence Critical risk of bias N/A
2.5 Data Synthesis … It included considerations for intake
assessment, details on the risks of using buprenorphine,
suboxone … of bias
RR Relative risk
SME Subject matter expert
SR Systematic review
SRP Scaling and root … N --
Overall risk of bias (domain 7) -- Low
Overall Risk
of Bias What is the overall risk of bias