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Total Results: 3,111 records

Showing results for "risk".

3021. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/diabetes-update-2015_disposition-comments.pdf
      January 01, 2015 - Most results were presented as relative risks. … Some of this, however, is difficult to clinically interpret because relative risks may be high yet … While the relative risk was 1.0 in ADOPT, the absolute risk difference was 0.1% (indicating a slightly … Therefore, baseline risks were different in the trials. … We have clarified that these are relative risk reductions from randomized controlled trials when used

3022. What do we know about how evidence of harm and benefit is communicated in other countries? (ppt file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/communicating_risk_international_king.ppt
      January 01, 2005 - information tool for use by consumers/patients Addresses treatment of a defined condition Addresses risks … Information Products from Other Countries How is risk and benefit communicated to health care consumers … Understanding NICE guidance—information for people who have or are at increased risk of cardiovascular … Strength of Evidence Yes Yes, OTC meds, NSAIDs, COX-2s, Topicals, Supple-ments Yes, pain relief and risk … of CV event or GI bleeding Yes, sort out benefit, risk, cost of choices Narrative, Q&A, Price comparisonchart

3023. Intermittent Inhalded Corticosteroids and Long-Acting Muscarinic Antagonists for Asthma (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-194-evidence-summary-corticosteroids-asthma.pdf
      October 01, 2017 - ICS controller • Does affect: – The risk of exacerbations requiring oral corticosteroids (low SOE) … combined with LABA as controller and quick relief vs. a higher ICS controller dose • Reduces the risk … ICS and LABA as controller at the same ICS dose • Reduces the risk of exacerbations measured as a … ICS controller • Does not affect the risk of exacerbations, regardless of definition (low SOE) • … ICS and LABA as controller at the same ICS dose • Reduces: – The risk of exacerbations defined as

3024. Dementia-Agitation-Aggression Executive (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/dementia-agitation-aggression_executive.pdf
      March 01, 2016 - aggression involves at least one other person (the target of the aggression) and can represent real risks … handling of incomplete data); reporting bias (selective reporting of outcomes or analyses); and other risks … to reduce the use of antipsychotic medications in people with dementia should continue, given the risks … Evidence about the risks associated with antipsychotic use in older adults is mounting. … Development of the risk appraisal measure: a brief screen to identify risk areas and guide interventions

3025. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cognitive-decline_executive.pdf
      March 01, 2017 - Although many putative risk factors have been identified, the challenge is to identify any interventions … Interventions represent one way to establish the veracity of risk factors. … Results were extracted only from studies assessed as having low to moderate risk of bias. … not the risk of CATD or of a combined outcome of MCI or CATD compared to placebo … Raloxifene may reduce risk of MCI.

3026. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cognitive-decline_executive.pdf
      March 01, 2017 - Although many putative risk factors have been identified, the challenge is to identify any interventions … Interventions represent one way to establish the veracity of risk factors. … Results were extracted only from studies assessed as having low to moderate risk of bias. … not the risk of CATD or of a combined outcome of MCI or CATD compared to placebo … Raloxifene may reduce risk of MCI.

3027. FRN 41 - Noninvasive Technologies for the Diagnosis of Coronary Artery Disease in Women: Future Research Needs (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis-future_research_1.pdf
      February 01, 2013 - Thirteen comparative studies reported risks. … Thus, ES-2 there was insufficient evidence regarding the comparative risks of various NIT modalities … Thirteen comparative studies reported risks. … Thus, there was insufficient evidence regarding the comparative risks of various NIT modalities in … ), the extant literature does not provide sufficient evidence to conclude whether safety concerns, risks

3028. Effective Health Care (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0488_12-27-2011.pdf
      January 01, 2011 - Staff-Generated PICO Population(s): People (primarily adults) at high risk for pancreatic cancer ( … sensitivity and specificity), practical issues (ease of use, costs, operator training), and potential risks … characteristics (e.g., family history, chronic pancreatitis, diabetes) compared with patients with no risk

3029. Depression-Postpartum-Screening Executive (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_executive.pdf
      May 01, 2013 - Institute of Medicine,5 maternal postpartum depression has also been associated with an increased risk … Summary judgments for these studies were assigned as high risk of bias, low risk of bias, or unclear … Ten were judged to have a high risk of biased results; the remainder were judged to be at low risk. … Two studies were rated low risk of bias, 10 high risk of bias, and 3 unclear risk of bias. … Only one study judged to be at high risk of bias provided a specific estimate of the effect of a risk

3030. Dietary-Supplements Executive (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/dietary-supplements_executive.pdf
      April 01, 2012 - heart failure or other cardiovascular disease use dietary supplementation and are thus placed at risk … of bias for the study as low, moderate, or high risk, and a second reviewer independently verified … Relative risk (RR) and post-treatment mean differences (MDs) were meta-analyzed using the DerSimonian … international normalized ratio; LDL-C = low-density lipoprotein-cholesterol; MD = mean difference; RR = relative … They recruited healthy subjects, or subjects with CHD or risk factors for CHD.

3031. Effective Health Care (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND__0250_05-20-2010.pdf
      January 01, 2010 - intervention, harm(s) of intervention, maintenance of sinus rhythm, mortality, accuracy and utility of risk … Prevention of Atrial Fibrillation and Progression to Heart Failure Population(s): Adults with, or at high risk … What are the accuracy and utility of methods of risk stratification to guide choice of therapy (e.g. … The evolution of newer anticoagulation agents as well as the risks and benefits when compared to older

3032. Grading_didactic_faculty_approved (ppt file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/grading.ppt
      January 01, 2010 - grade Four Required Domains: Risk of Bias Four Required Domains: Risk of Bias The risk of bias for … Risk-of-bias scores are denoted as high, medium, or low. … High risk of bias lowers the strength-of-evidence grade; low risk of bias raises the strength-of-evidence … Guiding Principles: Risk of Bias Guiding Principles: Risk of Bias The risk of bias based on the design … Guiding Principles: Risk of Bias Example Guiding Principles: Risk of Bias Example This is an example

3033. Accelerated Partial Breast Irradiation: Executive summary for the update of an ASTRO Evidence-Based Consensus Statement (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/topic-nomination-apbi-breast-cancer.pdf
      April 01, 2017 - define a group of patients with low-risk DCIS for whom observation confers a low absolute risk of IBTR … of IBTR.17 When analyzed by the ECOG 5194 risk criteria, the risk was 2% for patients meeting these … low-risk criteria. … However, given the low risk of IBTR in low-risk DCIS with wide local excision alone, coupled with favorable … results following APBI for low-risk DCIS in several series, the task force recommends inclusion of low-risk

3034. Methods Guide for Medical Test Reviews Chapter 7 (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-grading_methods.pdf
      July 01, 2012 - When the treatment of a disease has high associated risks, multiple tests are often used to assure the … false negatives depends on the severity of disease if there is a missed diagnosis, in addition to the risks … from the testing itself (i.e., if the test is invasive and associated with risks in and of itself). … of bias: • Low risk of bias • Medium risk of bias • High risk of bias Well designed and executed … Assessing risk of bias as a domain of quality in medical test studies.

3035. Transparency of Reporting Requirements: Omega-3 Fatty Acids and Cardiovascular Disease (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/transparency-omega-3_research-protocol.pdf
      September 02, 2016 - IF HIGH RISK OF BIAS, EXPLAIN IN NOTES. … IF HIGH RISK OF BIAS, EXPLAIN IN NOTES. … IF HIGH RISK OF BIAS, EXPLAIN IN NOTES. … , DM) ** Including diet but not CVD risk factors ** Including CVD risk factors, but not diet ** Neither … IF HIGH RISK OF BIAS, EXPLAIN IN NOTES.

3036. Omega-3 Fatty Acids and Cardiovascular Disease: Current State of the Evidence (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/fatty-acids-cardiovascular-disease_clinician.pdf
      July 01, 2017 - conducted to evaluate the effect of omega-3 fatty acids (FAs) on cardiovascular disease (CVD), its risk … , there is high strength of evidence (SOE) from RCTs that marine oil supplements do not affect the risk … Marine oil supplements also have no effect on the risk of atrial fibrillation (moderate SOE). … �) and no effect on atrial fibrillation (���) in populations with established CVD or at increased risk … of HDL-c and LDL-c (���) in healthy populations and in those with established CVD or at increased risk

3037. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/osteoporosis-bone-fracture_research-protocol.pdf
      May 14, 2010 - KQ2: How does fracture reduction resulting from treatments vary between individuals with different risks … c) What are the effects of adherence and persistence on the risk of fractures? … for OP fractures Health Outcomes: Change in fracture risk (KQ1,2) Change in BMD (KQ5[?] … KQ5 assesses the ability of risk predictors to identify people who are at greater risk of OP fracture … Assessment of fracture risk. Osteoporos Int 2005;16(6):581-9. 6.

3038. Effective Health Care (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0319_06-17-2009.pdf
      January 01, 2009 - whether these serum biomarkers provide evidence for the diagnosis or prognosis of sepsis for patients at risk … For patients at risk for, or in, sepsis, are there serum biomarkers available for the diagnosis and … For patients at risk for, or in, sepsis, does C reactive protein provide any utility in their management … For patients at risk for, or in, sepsis, does procalcitonin provide any utility in their Sepsis Biomarkers … For patients at risk for, or in, sepsis, does cortisol provide any utility in their management?

3039. Disposition of Comments for Progestogens for Prevention of Preterm Birth (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth-disposition-121205.pdf
      September 07, 2012 - Combs paper and the general need for larger datasets to assess harms such as IUFD and neonatal death risks … Results Page 53 of 518, the statement is made that “the meta-estimate combining these three trials is a relative … risk of 0.44 (95 percent CI: 0.26, 0.76)”. … I think the data indicating differential efficacy with different risks for preterm birth is sufficient … to allow the authors to make the statement that in future analyses, different risks would need to be

3040. Management of Suspected Opioid Overdose With Naloxone by Emergency Medical Services Personnel - Executive Summary (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-193-naloxone-executive-summary.pdf
      November 01, 2017 - Risk of Bias Assessment of Individual Studies We assessed risk of bias of included studies using … Effectiveness Reviews.34 We adapted criteria for assessing risk of bias from the U.S. … Studies were rated as “low risk of bias,” “medium risk of bias,” or “high risk of bias” based on the … [CI] 0.3 to 1.5), mean response time (8.0 vs. 7.9 minutes), or agitation/violence (6.0% vs. 7.9%, relative … risk [RR] 0.77, 95% CI 0.25 to 2.3).