Results

Total Results: 3,111 records

Showing results for "risk".

221. AHRQ Evidence-based Practice Center Program Research Gaps Summary: Primary Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
     March 01, 2022 - There may be a large increased risk of dizziness and sedation and a moderate increased risk of nausea … • Studies on the acute treatment of migraine that compare relative risks of medication overuse … studies that looked at prior or early postoperative opioid use found mostly strong associations (e.g., relative … Outcomes • Studies to assess risks and benefits including patient anxiety and disproportionate access … with antiresorptive osteoporosis drug treatment to best place these risks in the context of the effects

222. Making Healthcare Safer IV: Opioid Stewardship | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/mhs4-opioid-stewardship/protocol
     September 01, 2023 - However, opioids also carry well known risks, including for overdose, misuse, and opioid use disorder … tapering of opioids causing withdrawal, distress, and suicidal ideation. 3 Thus, any approach to mitigate risks … The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain. … Pain Management and the Opioid Epidemic: Balancing Societal and Individual Benefits and Risks of Prescription … The Cochrane Collaboration's tool for assessing risk of bias in randomised trials.

223. AHRQ Evidence-Based Practice Center (EPC) Program Research Gaps Summary: Pain Management (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
     January 01, 2023 - There may be a large increased risk of dizziness and sedation and a moderately increased risk of nausea … of sedation, and large increased risk of nausea and dizziness … Extracted whole-plant products with higher THC than CBD may be associated with large increases in risk … • Studies on the acute treatment of migraine that compare relative risks of medication-overuse … use of risk prediction instruments impacts treatment decisions and outcomes.

224. Han (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/han.pdf
     December 26, 2012 - based input for shared decision  making, by providing estimates of the individual probabilities of risks … Slide 21: Representing  indeterminacy in risk estimates: new approaches • Limited  evidence on … effectiveness o No apparent effects on risk perceptions o Increase subjective uncertainty about   … One bar shows risk  as a solid bar.  The other shows risk  as a blurred bar.   … Slide 25: Methodological problems • Separation of strength of recommendation (risk) vs. quality  

225. Disposition of Comments Report for Treatment of Depression During Pregnancy and the Postpartum Period (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_disposition-comments.pdf
     July 08, 2014 - Socioeconomic status may be an important modifying factor, but does not argue against the risks associated … We agree that it is very important to understand the risks of antidepressant treatment to pregnant and … postpartum women and offspring, as well as the risks of depression to pregnant and postpartum women … unclear whether the signal evidence from this systematic review warrants singling out these three risks … Added definition for RRR: relative risk reduction (reported in the study rather than relative risk)

226. Comparative Effectiveness Review No. 234 Evidence Summary: Management of Primary Headaches in Pregnancy (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-234-headaches-pregnancy-summary.pdf
     November 01, 2020 - gabapentin, and valproate may have similar adverse effect profiles, but lamotrigine may have a low risk … Lamotrigine may have a lower risk of adverse effects: no increased risk of spontaneous abortion, stillbirth … particular) (low to moderate SoE for specific adverse effects) and antihistamines (moderate SoE) had low risks … no increased risk or unknown risk of other fetal/child AEs, this table includes only the indicator for … increased risk.

227. Disposition of Comments: Technical Brief 37 Prevention, Diagnosis, and Management of Opioids, Opioid Misuse, and Opioid Use Disorder in Older Adults (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/tech-brief-37-opiod-use-adults-comments.pdf
     November 03, 2020 - Such comparisons are not addressing Q2 or telling you about risks among opioid types. … of opioid prescribing, including risks for overdose, suicide, and death. … are fundamentally different than risks associated with prevalent use. … studies that looked at prior or early postoperative opioid use found mostly strong associations (e.g., relative … Any discussion of opioid risks should also include the risks of rapid, inappropriate, forced tapering

228. Medical-Evidence-Communication Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/medical-evidence-communication_research-protocol.pdf
     July 31, 2012 - • Absolute relative risk and relative risk reduction are more understandable than number needed to … treat presentations.18-22 • Absolute relative risk tends to be less persuasive than relative risk reduction … the strength of evidence (also called ambiguity), uncertainty about the significance of particular risks … severity), uncertainty about the complexity of information (e.g., the multiplicity or stability of risks … ), and uncertainty resulting from ignorance about risks.

229. Update of Comparative Effectiveness of Lipid-Modifying Agents | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/high-cholestorol-medicines-update/research-protocol
     December 01, 2019 - Moderate-risk patients are those with two or more risk factors and a 10-year CHD risk less than 20 percent … therapy if the LDL-c is above 130 mg/dL; whereas for moderate-risk patients with a 10-year CHD risk … (10-year CHD risk ≥20% and/or a mean LDL ≥190 mg/dL) and moderate CVD risk (10-year CHD risk 10–20% … DerSimonian and Laird formula for continuous outcomes. 37 We will calculate a pooled effect estimate of the relative … by CHD risk.

230. Venous Thromboembolism Prophylaxis in Orthopedic Surgery | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/blood-clots-hip-knee-surgery/research
     December 01, 2019 - We used random effects derived relative risks (RR) for most analyses and Peto's Odds Ratios (OR) in comparisons … Conclusions In major orthopedic surgery, while the risk of developing deep vein thrombosis is highest … outcomes, or had offsetting effects where benefits of one class on efficacy was tempered by an increased risk

231. Diagnosis and Management Pressure Ulcer The questions we would like answered by this evidence review are the following: 1. How can we identify patients at risk for pressure ulcers in the hospital or long-term care setting and what is the… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/diagnosis-and-management-pressure-ulcer-the-questions-we-would-like-answered-by-this-evidence-review-are-the-following-1-how-can-we-identify-patients-at-risk-for-pressure-ulcers-in-the-hospital-or-long-term-care-setting-and-
     November 01, 2017 - How can we identify patients at risk for pressure ulcers in the hospital or long-term care setting and … How can we identify patients at risk for pressure ulcers in the hospital or long-term care setting and … would like answered by this evidence review are the following: How can we identify patients at risk … setting and what is the evidence for validity and reliability of various instruments for estimating these risks … Describe any health-related risks, side effects, or harms that you are concerned about.

232. Making Healthcare Safer IV: Fatigue and Sleepiness of Clinicians Due to Hours of Service (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/fatigue-sleepiness-protocol.pdf
     July 01, 2023 - Patient safety risks due to fatigue and sleepiness of healthcare workers were not addressed in MHS … Fatigue Risk Management in the Workplace. … How effective are Fatigue Risk Management Systems (FRMS)? A review. … The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. … ROBINS-I: a tool for assessing risk of bias in non- randomised studies of interventions.

233. Version 2_Risk of Reinfection From SARS-CoV-2 -- An Update of an Antibody Response Following SARS-CoV-2 Infection and Implications for Immunity: A Living Rapid Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/version-2-risk-of-reinfection-from-SARSCoV2_0.pdf
     December 31, 2022 - Between March and August 2021, several epidemiological studies have been published comparing infection risks … for various factors), our meta-analysis used absolute counts of events in both groups to obtain a relative … most concerning. 45 A study from Brazil suggested higher reinfection 12 risks … This estimate is formally one minus the relative risk (RR); i.e., protection estimate = 1 – RR. … Risk of Bias Outcome Ascertainment Risk of Bias Outcome Classification Risk of Bias Risk of

234. Treatment To Prevent Fractures in Men and Women With Low Bone Density or Osteoporosis: Update of a 2007 Report | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/osteoporosis-bone-fracture/research
     October 01, 2020 - Ibandronate and raloxifene reduce the risk of vertebral but not nonvertebral fractures. … Risedronate decreases the risk of vertebral and nonvertebral fracture among men with osteoporosis. … Among those treated with glucocorticoids, fracture risk reduction was demonstrated for risedronate and … Decreased adherence to bisphosphonates is associated with less than optimal reduction in the risk of … evidence is low for benefits of treatment for other populations, including men; for the benefits and risks

235. Prehospital EMS Blood Transfusion and Fluid Interventions for Hemorrhagic Shock (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-protocol-amendment.pdf
     February 04, 2025 - Assessment of Methodological Risk of Bias of Individual Studies We define the risk of bias as the risk … Studies will be rated as “low risk of bias,” “medium risk of bias,” or “high risk of bias.” … Studies rated “low risk of bias” are considered to have the least risk of bias, and their results are … 100-point scale SMD >0.8 RR/OR ≥2.0 Abbreviations: MD = mean difference; OR = odds ratio; RR = relative … quality improvement; RCT = randomized controlled trial; ROSC = return of spontaneous circulation; RR = relative

236. Prehospital EMS Blood Transfusion and Fluid Interventions for Hemorrhagic Shock | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/ems-blood-transfusion/protocol
     February 01, 2025 - Assessment of Methodological Risk of Bias of Individual Studies We define the risk of bias as the risk … Studies will be rated as “low risk of bias,” “medium risk of bias,” or “high risk of bias.”  … Studies rated “low risk of bias” are considered to have the least risk of bias, and their results are … to 100-point scale SMD >0.8 RR/OR ≥2.0 Abbreviations: MD = mean difference; OR = odds ratio; RR = relative … quality improvement; RCT = randomized controlled trial; ROSC = return of spontaneous circulation; RR = relative

237. Comparative Effectiveness of Epoetin and Darbepoetin for Managing Anemia in Patients Undergoing Cancer Treatment–An Update to the 2006 Report | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/cancer-anemia-update/research-protocol
     December 01, 2019 - To decrease these risks, as well as the risk of serious cardio- and thrombovascular events, use the lowest … For binary data, the relative risk will be used as a measure of treatment effect. … Risks of blood transfusion. Anesthesiol Clin North America 2005;23(2): 241-52. … Transfusion risks of yesterday and of today. Transfus Clin Biol 2003;10(1): 1-5. … and relative risk scales.

238. My nomination is about comparing outcomes of different glaucoma treatments, particularly canaloplasty to trabeculectomy and to medical therapy alone. | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/my-nomination-is-about-comparing-outcomes-of-different-glaucoma-treatments-particularly-canaloplasty-to-trabeculectomy-and-to-medical-therapy-alone
     November 01, 2017 - Glaucoma often occurs with age, and African-Americans are at higher risk. 5. … Identification of a disease or condition:   Screening or diagnosis/identification for a particular disease, or risk … assessment for a disease   Risks or harms that can come from a disease identification tool or test … Harms: Are there risks, side effects, or harms you are concerned about? … Does age modify this risk? 10.

239. Physiologic Predictors of the Need for Trauma Center Care: A Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/predictors-trauma-care_research-protocol.pdf
     May 31, 2017 - e.g., odds ratio, relative risk, hazards ratio); (2) discrimination (e.g., area under the receiver operating … of bias,” “medium risk of bias,” or “high risk of bias.” … Adjusted risk estimates may include odds ratios, risk ratios, and hazard ratios. … (e.g., odds ratio, relative risk, hazards ratio); (2) discrimination (e.g., area under the receiver … (e.g., odds ratio, relative risk, hazards ratio); (2) discrimination (e.g., area under the receiver

240. Comparative Effectiveness of Dietary Supplement Versus No Dietary Supplement Use in Adults Taking Cardiovascular Drugs | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/dietary-supplements/research-protocol
     December 01, 2019 - Nomination: The original nomination for this review was for a comparative effectiveness review of the risks … in the United States, which includes dietary supplementation, a request to evaluate the benefits and risks … number of events or number of patients with events among study treatment groups to calculate rates, relative … risk, and absolute risk differences (ARD). … For observational studies, we will extract crude rates or relative measures of the association (relative