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effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-245-breast-reconstruction-after-mastectomy-disposition-comments.pdf
October 01, 2021 - For example, the discussion of the risks of
reconstruction with breast implants barely mentions
breast … For
example, when discussing the risks of reconstruction
with breast implants, the draft only mentions … mention that when mastectomies are
unnecessary, choosing lumpectomy will make
reconstruction (with its risks … Research
Introduction The report barely mentions the autoimmune, connective
tissue, and neurological risks … It states “These risks of systemic
symptoms and BIA-ALCL led the U.S.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0411_02-10-2011.pdf
January 01, 2011 - In addition, they question whether the benefits and harms of these
tests vary by the risk of the surgical … procedure, the clinical condition, or comorbidities
and risks of particular patients. … Do the benefits or harms of routine preoperative tests vary by the risk of the
surgical procedure (low … vs. medium vs. high risk)? … benefits or harms of
routine preoperative tests vary by the clinical conditions, comorbidities, or risks
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-3.pdf
June 01, 2022 - difference: CI = confidence interval; KQ = Key Question; RCT = randomized controlled
trial; RR = relative … scale, 95% confidence interval [CI] −0.93 to −0.67,
I2=71%), likelihood of a pain response (44 trials, relative … mitigation strategies, dose-
dependent risks of opioids, and management of opioid use disorder; for … In patients with chronic pain, what are the comparative risks of opioids
versus nonopioid therapies … adverse events; CI = confidence interval; MD = mean difference; RCT = randomized controlled trial; RR = relative
-
effectivehealthcare-admin.ahrq.gov/products/predictors-trauma-care/research-protocol
December 01, 2019 - ., odds ratio, relative risk, hazards ratio); (2) discrimination (e.g., area under the receiver operating … of bias," "medium risk of bias," or "high risk of bias." … Adjusted risk estimates may include odds ratios, risk ratios, and hazard ratios. … ., odds ratio, relative risk, hazards ratio); (2) discrimination (e.g., area under the receiver operating … ., odds ratio, relative risk, hazards ratio); (2) discrimination (e.g., area under the receiver operating
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/chronic-pain-opioid-treatment_research-protocol.pdf
December 19, 2013 - Evidence-based Practice Center Systematic Review Protocol
Project Title: The Effectiveness and Risks … In patients with chronic pain, what are the risks of opioids versus placebo or no
opioid on: 1) opioid … for initiating and titrating opioids for outcomes related to pain, function, and
quality of life; risks … Risk assessment and risk mitigation strategies
Source: www.effectivehealthcare.ahrq.gov
Published … Analytic Framework for the Effectiveness and Risks of Long-term Opioid Treatment of
Chronic Pain
IV
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/omega-3-maternity_executive.pdf
October 01, 2016 - observational studies found no
consistent effects of maternal or infant n-3
FA supplementation on risks … Key Question 3: Maternal or childhood adverse events:
– What are the short and long-term risks related … Breastfeeding women
o Term or preterm human infants at or after birth
– What are the short and long-term risks … Dermatitis, and Respiratory
Conditions
Additional outcomes newly included in the current report
were risks … for atopic dermatitis/eczema, risks for allergies,
and risks for respiratory illnesses, including asthma
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/s81.pdf
October 01, 2007 - commonly
used measure of discrimination, in this case equal to (sensi-
tivity � specificity)/2,22 and relative … risk (RR). … risk. … 31 38.21 0.0000
Diabetes Mellitus (CCS D-50)† 0.08 4 11 97 0.54 3 3.41 0.0134
*P value is for the relative … risk.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
March 01, 2011 - Based on a single RCT with
moderate risk of bias, we found low strength of
evidence that the risk of … combination therapy containing
rosiglitazone than with a combination of metformin and
a sulfonylurea (relative … risk [RR] 2.1). … Hypoglycemia High The risk of mild to moderate hypoglycemia with sulfonylureas
exceeds the risk with … low density lipoproteins;
mg/dL = milligrams per deciliter; RCT = randomized controlled trial; RR = relative
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/mhs4-opioid-stewardship-protocol.pdf
July 01, 2023 - However, opioids also carry well known risks,
including for overdose, misuse, and opioid use disorder … tapering of opioids
causing withdrawal, distress, and suicidal ideation.3 Thus, any approach to mitigate risks … The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic
Pain. … Pain Management and the Opioid Epidemic:
Balancing Societal and Individual Benefits and Risks of Prescription … The Cochrane Collaboration's tool for assessing risk of bias in
randomised trials.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-protocol.pdf
September 24, 2024 - Assessment of Methodological Risk of Bias of Individual Studies
We define the risk of bias as the risk … Studies will be
rated as “low risk of bias,” “medium risk of bias,” or “high risk of bias.” … Studies rated “low risk of bias” are considered to have the least risk of bias, and their results are … 100-point scale
SMD >0.8
RR/OR ≥2.0
Abbreviations: MD = mean difference; OR = odds ratio; RR = relative … quality improvement; RCT = randomized controlled trial; ROSC = return of spontaneous circulation;
RR = relative
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
March 01, 2012 - reduction
resulting from treatments vary between individuals with
different risks for fracture as … with different risks for fracture
as determined by bone mineral density, risk
assessment score, prior … risk. … How does fracture risk reduction resulting from treatments vary between individuals with different risks … Given the established adverse
events associated with treatment, and newly identified
risks such as
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/prostate-cancer_executive.pdf
February 01, 2008 - All treatments have
risks of complications, although frequency and severity
may vary. … What are the comparative
risks, benefits, and outcomes of therapies? … risk disease. … However, the
relative risk of surgery-related complications adjusted
for patient age, race, and comorbidity … The
relative risk of surgery-related complications adjusted for
patient age, race, and comorbidity,
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effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-236-maternal-fetal-child-outcomes-disposition-comments.pdf
April 15, 2021 - In response, the EPC
added a table to the discussion section on absolute risks of harms when available … presented in the
context of the likelihood that this complication will occur
and the difference in the relative … column whether the
effect is a benefit or a harm and indicate
the magnitude of effect in terms of relative … risks in the results column. … The key information about treatment risks, harms,
and evidence can still be provided without relying
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/thompson_eccs2012.pdf
January 01, 2012 - Louis,
MO
Slide 2: Informed Decision Making
(1 of 2)
• Understands
the
nature
and risks …
• Understands
the
risks
and benefits
• Understands
alternatives
• Participates … .
o Presenting risk information increased perceived risk without
increasing
worry,
fear,
or … o How should risk information be presented? … .
o Include social math strategies.
o Graphically show risks/harms, as well as benefits (facts boxes
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/nonopioid-chronic-pain-summary.pdf
April 01, 2020 - Harms and adverse events:
– What are the risks of nonopioid
pharmacologic agents for harms including … points on a 0 to 100-point scale
• SMD >0.8
• RR/OR ≥2.0
MD = mean difference; OR = odds ratio; RR = relative … response with SNRI antidepressants
(odds ratio [OR] 1.61 to 2.33) while we found a
moderate effect (relative … ).15 Differences in magnitude could be due to
the addition of 15 studies in our report, reporting
relative … risks rather than odds ratios, and using
direct comparisons rather than network analysis.
-
effectivehealthcare-admin.ahrq.gov/products/coronary-artery-disease-testing/research-protocol
December 01, 2019 - percutaneous coronary intervention [PCI] or coronary artery bypass grafting [CABG])
Harms, risks … (e.g., antiplatelet therapy)
Any need for subsequent revascularization (PCI or CABG)
Harms, risks … contrast-related harms, adverse reaction to medications used for stress testing), vascular complications
Risks … intermediate to high CAD risk. … Risks and complications of coronary angiography: a comprehensive review.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/opioids-oa-protocol.pdf
June 29, 2019 - many special considerations when using (or misusing)
opioids.5
Aside from misuse, other important risks … The risks of harm may also
be exacerbated by the high frequency at which older adults see multiple providers … anti-inflammatory drugs) due to
impaired liver or kidney function, hypertension,22-24 other cardiac risks … Medicine text Pain
Management and the Opioid Epidemic: Balancing Societal and Individual Benefits and Risks … Pain management and the opioid epidemic : balancing societal
and individual benefits and risks of prescription
-
effectivehealthcare-admin.ahrq.gov/products/opioids-older-adults/protocol
August 01, 2020 - many special considerations when using (or misusing) opioids. 5
Aside from misuse, other important risks … The risks of harm may also be exacerbated by the high frequency at which older adults see multiple providers … anti-inflammatory drugs) due to impaired liver or kidney function, hypertension, 22-24 other cardiac risks … Medicine text Pain Management and the Opioid Epidemic: Balancing Societal and Individual Benefits and Risks … Pain management and the opioid epidemic : balancing societal and individual benefits and risks of prescription
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
April 01, 2015 - • Because of high risk of bias and small sample sizes,
evidence is insufficient to address the risks … Eight observational studies (all high risk of bias)
addressed the risks of rebound disease activity … Twelve observational studies (all high risk of bias)
addressed the benefits and risks to mothers and … Thus, personal
preferences about risks take on more weight. … Multiple sclerosis
patients’ benefit-risk preferences: serious adverse event risks versus
treatment
-
effectivehealthcare-admin.ahrq.gov/products/stroke-atrial-fibrillation/research-protocol
December 01, 2019 - Current Evidence for Risk Stratification and Stroke Prevention
Risk Stratification
A number of studies … Despite existing risk-stratification tools with overlapping characteristics, the major risk factors for … evolution of the newer anticoagulation agents investigated in the large trials listed above—as well as the risks … Poor (high risk of bias). … A population-based study of the long-term risks associated with atrial fibrillation: 20-year follow-up