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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/prostate-cancer-therapies-update_executive.pdf
December 01, 2014 - Institutes
of Health (NIH) State-of-the Science Conference in
December 2011 to better understand the risks … For KQ 1, we summarize and discuss comparative
risks, benefits, and outcomes of therapies. … KQ 1: Comparative Risks and Benefits of
Therapies for Clinically Localized Prostate Cancer
Eight RCTs … in 16 publications addressed comparative
risks and benefits for various therapies. … prostatectomy;
RPP = radical perineal prostatectomy; RRP = radical retropubic prostatectomy; RR = relative
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-233-diverticulitis-evidence-summary.pdf
October 01, 2020 - Misdiagnoses on CT may not increase the risk of poor
clinical outcomes (low SoE). … diverticulitis, antibiotic
treatment may not affect pain symptoms, length of hospital stay, recurrence risk … have similar rates of CRC diagnoses as those who
did not; however, no studies evaluated comparative risks … or older or who had complicated diverticulitis (with abscess,
peritonitis, etc.) are at increased risk … no evidence of differences,
ultimately, in rates of CRC; however, no studies evaluated comparative risks
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effectivehealthcare-admin.ahrq.gov/sites/default/files/s158.pdf
October 01, 2007 - Generaliza-
tion from trials can be erroneous because effect sizes, base-
line risks, and comorbidity … Without adjustment for smoking, the relative risk of lung
cancer in those exposed to diesel exhaust was … This multiple im-
putation led to an estimate of the relative risk for lung cancer
and exposure to diesel … Because the relative risk
for vasectomy and myocardial infarction was essentially the
same before and … Correction of logistic regression
relative risk estimates and confidence intervals for measurement error
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/meditation_research-protocol.pdf
October 17, 2012 - The overall risk of bias will be assessed as:
• Good (low risk of bias). … differences or relative risks using a DerSimonian and Laird random effects model. … differences or relative risks with 95% confidence intervals (CI) for the individual studies. … differences or relative risks using a
DerSimonian and Laird random effects
model. … differences or relative risks with 95%
confidence intervals (CI) for the
individual studies.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/medication-therapy-management-1_research.pdf
July 01, 2012 - in High Risk Medicare Beneficiaries Toolkit
Daniel R. … Improving Medication Safety in High Risk Medicare
Beneficiaries Toolkit. … reviews pharmacodynamic and pharmacokinetic changes that are
common in elderly adult, explains the risks … • The patient is at risk for a potential ADE. … The patient is at risk for a potential
ADE.
a.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/prostate-cancer-risk-assessment-genes_disposition-comments.pdf
July 03, 2012 - Disposition of Comments Report for Multigene Panels in Prostate Cancer Risk Assessment
Source: http … Review Disposition of Comments Report
Research Review Title: Multigene Panels in Prostate Cancer Risk … Multigene Panels in Prostate Cancer Risk Assessment. … and other clinical risk
assessment test.” … The risk significance will certainly
increase once the actual causal variant has been identified.
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effectivehealthcare-admin.ahrq.gov/products/effect-protein-intake/protocol
December 01, 2023 - will be rated using the Cochrane Risk of Bias tool 2.0 33 as low risk, some concerns (moderate risk … moderate risk, or high risk. … Sodium and Potassium Intake: Effects on Chronic Disease Outcomes and Risks. … Timing, and Study design/setting
RCT
Randomized Controlled Trial
RR
Relative … Risk
RoB
Risk of Bias
TOO
Task Order Officer
U.S.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments-rapid-review.pdf
March 01, 2024 - in risk. … There were no significant differences in risks for acute kidney injury,
cardiac arrhythmia, infection … Risks for acute kidney injury, hypertension,
hypotension, seizure, and transfusion-associated lung injury … Studies from other regions might also report elevated risks for additional serious adverse
events. … Assessment RoB: Low risk
Reporting RoB: Low risk
Overall RoB: Low risk
Pub.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/monitoring-programs-protocol.pdf
January 01, 2024 - Coordinator role, along with a number of
policies to prevent drug shortages and mitigate supply chain risks … reported supply chain shortages in
2021,8 and supply chain shortages were second among the top 10 risks … Supply chain shortages ranked
second among Top 10 risks facing healthcare
organizations [internet]. … Meeting (PA):
ECRI; 2022. https://blog.ecri.org/supply-chain-
shortages-ranked-second-among-top-10-risks … https://blog.ecri.org/supply-chain-shortages-ranked-second-among-top-10-risks-facing-healthcare-organizations
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/weight-gain-prevention_research-protocol.pdf
January 01, 2020 - • Poor (high risk of bias). … differences or relative risks using a DerSimonian and
Laird random effects model. … differences or relative risks with 95% confidence intervals
(CI) for the individual studies. … Eating pathology and obesity in women at
risk for breast cancer recurrence. … Multiple risk factors for cardiovascular disease and diabetes mellitus.
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effectivehealthcare-admin.ahrq.gov/products/weight-gain-prevention/research-protocol
December 01, 2019 - Poor (high risk of bias). … or relative risks using a DerSimonian and Laird random effects model. … differences or relative risks with 95% confidence intervals (CI) for the individual studies. … Eating pathology and obesity in women at risk for breast cancer recurrence. … Multiple risk factors for cardiovascular disease and diabetes mellitus.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/aggression_executive.pdf
October 01, 2016 - First is how to best balance the
benefits and risks of seclusion or restraints
with those of various … seclusion and mechanical
restraint.44
CI = confidence interval; N = number; NR = not reported; RR = relative … risk; vs. = versus. … CI = confidence interval; KQ = Key Question; N = number; RR = relative risk; vs. = versus. … confidence interval; CRT= cluster randomized trial; KQ = Key Question; N = number; NR = not reported; RR = relative
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effectivehealthcare-admin.ahrq.gov/products/nsaids-gastroprotective-therapy/research
November 01, 2017 - Risk of Peptic Ulcer Hospitalizations in Users of NSAIDs With Gastroprotective Cotherapy Versus Coxibs … Abstract
Background and Aims
The primary strategies to reduce the risk of serious gastropathy caused … This risk was reduced by 39% (16%-56%, 95% CI) for current users of NSAIDs with gastroprotective cotherapy … Concurrent users of NSAIDs and proton pump inhibitors had a 54% (27%-72%) risk reduction, very similar … May 15, 2012
Summary Variables in Observational Research: Propensity Scores and Disease Risk
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effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/diagnosis-and-treatment-of-low-back-painbr-key-questionsbr-olliin-patients-with-low-back-pain-what-are-the-benefits-and-harms-of-identifying-risk-factors-for-chronicity-and-targeting-treatment-based-on-assessed-riskliliin-pa
November 01, 2017 - questions:
- In patients with low back pain, what are the benefits and harms of identifying risk … questions:
- In patients with low back pain, what are the benefits and harms of identifying risk … pain: Key questions: In patients with low back pain, what are the benefits and harms of identifying risk … factors for chronicity and targeting treatment based on assessed risk? … Describe any health-related risks, side effects, or harms that you are concerned about.
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effectivehealthcare-admin.ahrq.gov/products/diverticulitis/research
January 01, 2022 - Misdiagnoses on CT may not increase the risk of poor clinical outcomes (low SoE). … have similar rates of CRC diagnoses as those who did not; however, no studies evaluated comparative risks … acute diverticulitis, there is low SoE that initial outpatient or inpatient management have similar risks … of recurrence or elective surgery, but insufficient evidence regarding risk of treatment failure and … The risk of recurrence is not reduced by 5-aminosalicylic acid (5-ASA) (high SoE).
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/acs-pci-adjunctive-devices_research-protocol.pdf
July 01, 2010 - For dichotomous
outcomes, weighted averages will be reported as relative risks and risk differences … expected, a DerSimonian and Laird random-effects model will be used when pooling
data and calculating relative … risks, risk differences, and 95 percent confidence
intervals.9 When pooling continuous outcomes, weighted … This system uses four required domains—risk of bias, consistency,
directness, and precision. … Risk of Bias
Risk of bias is the degree to which the included studies for any given outcome or
comparison
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effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/impact-healthcare-algorithms-racial-ethnic-disparities-March-3.pdf
July 01, 2023 - risk
Novel risk prediction algorithm for cardiovascular disease
COAG for warfarin dosing
Added health … outcome variables 1 USPSTF-2020 for lung cancer risk
Added measures of SDOH 1 Novel risk prediction … Novel risk prediction algorithm for postpartum depression
Donor Risk Index for liver transplant suitability … deployed in health systems
but regulation is not enough, and
clinicians cannot bear all liability risks … How can the AI RMF help organizations manage the risks from AI bias?
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effectivehealthcare-admin.ahrq.gov/products/cad-women-diagnosis/research
December 01, 2019 - symptoms suspicious for CAD, (2) predictors affecting test accuracy, (3) ability of NITs to provide risk … prognostic information, inform decisionmaking about treatment options, and affect clinical outcomes, and (4) risks … There is insufficient evidence on the comparative effectiveness of NITs to provide risk stratification … Thirteen comparative studies reported risks. … Thus, there was insufficient evidence regarding the comparative risks of various NIT modalities in women
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effectivehealthcare-admin.ahrq.gov/products/stroke-afib-update/research-protocol
September 01, 2019 - patient populations not included or not well-represented in clinical trials and to better understand the relative … risks and benefits of these drugs based on individual patient characteristics. … score
CHADS2-VASc score
Framingham risk score
ABC stroke risk score
Individual risk factors … Poor (high risk of bias). … A population-based study of the long-term risks associated with atrial fibrillation: 20-year follow-up
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effectivehealthcare-admin.ahrq.gov/products/medical-evidence-communication/research-protocol
December 01, 2019 - Absolute relative risk and relative risk reduction are more understandable than number needed to treat … presentations. 18-22
Absolute relative risk tends to be less persuasive than relative risk reduction … the strength of evidence (also called ambiguity), uncertainty about the significance of particular risks … severity), uncertainty about the complexity of information (e.g., the multiplicity or stability of risks … ), and uncertainty resulting from ignorance about risks.