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Showing results for "risk".

121. Therapies for Clinically Localized Prostate Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/prostate-cancer-therapies/report
     January 01, 2021 - Mortality reductions may be limited to men age 65 and older and those with intermediate risk disease. … One investigator rated risk of bias (RoB), extracted data, and assessed certainty of evidence; a second … WW’s effect on mortality may vary by tumor risk and age but not by race, health status, comorbidities … EBR plus AD reduces mortality versus EBR alone in higher risk CLPC but may worsen sexual function. … Adding low-dose-rate BT to 3D-conformal EBR and AD may reduce mortality in higher risk CLPC.

122. Nonpharmacological Versus Pharmacological Treatment for Patients With Major Depressive Disorder: Current State of the Evidence | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/major-depressive-disorder/clinician
     June 01, 2021 - statistically significant difference; CBT = cognitive behavioral therapy; CI = confidence interval; RR = relative … risk; SGA = second-generation antidepressant; SOE = strength of evidence SGAs versus CBT … statistically significant difference; CBT = cognitive behavioral therapy; CI = confidence interval; RR = relative … major depressive disorder; SGA = second-generation antidepressant All SGAs Increased risks … That effective nonpharmacological and pharmacological treatment options are available for MDD The risks

123. Treatment of Depression in Children and Adolescents: A Systematic Review - Evidence Summary (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/Evidence%20Summary_0_0.pdf
     April 01, 2020 - data (e.g., re-experiencing trauma, suicidality),5 which leads to uncertainty about weighing the risks … Questionnaire-Parent; n= number; NOS = not otherwise specified; RCT = randomized controlled trial; RR = relative … c One high risk-of-bias study (n=180) reported a substantial risk (relative risk: 5.15, 95% CI, 1.17 … Rating Scale; MDD = major depressive disorder; n/N =number; RCT = randomized controlled trial; RR = relative … statistically significant differences in suicidal ideation or behavior for the entire class, although the risks

124. Disposition of Comments Report for Stroke Prevention in Atrial Fibrillation (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_disposition-comments.pdf
     August 23, 2013 - bleeding risk, our roundtable experts concluded that more research is needed into specific risks … stated a measure of “% reduction” and it’s not clear if this point estimate (95% CI) is calculated on relative … (95% CIs) are reported as HRs, however, Connolly et al 2009 reported RE-LY efficacy endpoints as relative … We now clarify that the % reduction was a relative risk reduction. … We have highlighted the risks associated with use of dabigatran re: risk of MI as well as dyspepsia

125. Hepatitis-C Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
     November 01, 2012 - risks.35 When present, statistical heterogeneity was explored through subgroup and sensitivity analyses … Relative risk estimates ranged from 1.01 to 1.33 in the four trials and may have varied in part due … Relative risk estimates ranged from 0.89 to 1.2. Moderate 11 Table A. … risk estimates for SVR in men vs. women, and no clear difference in relative risk estimates for Black … for risk of harms that were similar to the risk estimates based on all trials.

126. The Effect of Dietary Digestible Carbohydrate Intake on Risk of Type 2 Diabetes, Growth, Size, and Body Composition | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/effect-dietary-digestible/protocol
     December 01, 2023 - accumulation that presents a risk to health. … Assessment of the Risk of Bias of Individual Studies We will evaluate the risk of bias of the included … unclear risk of bias studies and not rate down the SOE. … Diet, lifestyle, and the risk of type 2 diabetes mellitus in women. … RoB 2: a revised tool for assessing risk of bias in randomised trials.

127. Interventions To Improve Cardiovascular Risk Factors in People With Serious Mental Illness | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/mental-illness-heart/research
     December 01, 2019 - Home Evidence Reports Interventions To Improve Cardiovascular Risk … SHARE: Interventions To Improve Cardiovascular Risk … We conducted a systematic review to evaluate interventions to improve CVD risk factors in adults with … profile among adults with SMI at elevated risk of CVD. … Project Timeline Interventions To Improve Cardiovascular Risk Factors in People With Serious Mental

128. S89 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/s89.pdf
     October 01, 2007 - †One-sided test; when relative risk �1, the log likelihood ratio was set to 0. … Cases in the 42 d After Meningococcal Vaccination by Week 106 Relative Risk in Vaccinated Group Log … †One-sided test; when relative risk �1, the log likelihood ratio was set to 0. … The dashed line depicts the relative risk. TABLE 4. … Cases of Thrombocytopenia in the 42 d After Vaccination Relative Risk Log Likelihood Ratio*Observed

129. Peripheral Artery Disease (PAD) - defined as peripheral artery disease of the lower extremities 1) Does aspirin reduce the risk of adverse cardiovascular events (MI, stroke, cardiovascular death) in patients with PAD? Is there a… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/peripheral-artery-disease-pad-defined-as-peripheral-artery-disease-of-the-lower-extremities-1-does-aspirin-reduce-the-risk-of-adverse-cardiovascular-events-mi-stroke-cardiovascular-death-in-patients-with-pad-is-there-a-diffe
     November 01, 2017 - Disease (PAD) - defined as peripheral artery disease of the lower extremities 1) Does aspirin reduce the risk … ) defined as peripheral artery disease of the lower extremities Does aspirin reduce the risk … Improvements in mortality and morbidity and quality of life Describe any health-related risks, side … Bleeding risks associated with anti-platelet therapy in patients with PAD and co-morbid disease … It is associated with a 5 fold increased risk of adverse cardiovascular events.

130. Emerging Approaches to Diagnosis and Treatment of Non–Muscle-Invasive Bladder Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/bladder-cancer-non-muscle-invasive/research
     December 01, 2019 - versus white light cystoscopy, but results were inconsistent, and there was no difference in risk of … recurrence (for bacillus Calmette-Guérin [BCG], relative risk [RR], 0.56; 95% confidence interval [CI … BCG was also associated with decreased risk of bladder cancer progression, but no intravesical agent … was associated with decreased risk of all-cause or bladder cancer mortality. … Intravesical therapy reduces risk of bladder cancer recurrence versus no intravesical therapy.

131. Stroke Prevention in Atrial Fibrillation | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/stroke-atrial-fibrillation/research
     December 01, 2019 - updates previous reviews, particularly with regard to these newer treatment options and the optimal risk … , 17 relevant to predicting bleeding risk, 43 relevant to interventions for preventing thromboembolic … Vascular disease, Age 65–74, Sex category female) scores have the greatest discrimination for stroke risk … superior to warfarin in reducing the incidence of stroke (including hemorrhagic) or systemic embolism (relative … scores we reviewed, whereas HAS-BLED provides the best discrimination of bleeding risk.

132. Disposition of Comments Report for Oral Contraceptive Use for the Primary Prevention of Ovarian Cancer (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_disposition-comments.pdf
     June 07, 2013 - increased risk?? decreased risk?? … question from this reviewer is whether an OR was actually calculated for cohort studies or whether a relative … age-specific incidences (rates) to probabilities, then, assuming that the odds ratios were estimates of relative … risks, applied the OR to the probabilities. … However, it is interesting to note that the results of relative risk by duration of oral contraceptive

133. Radiation Therapy for Brain Metastases | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/radiation-therapy-brain-metastases/research
     January 01, 2022 - Risk of bias varied, 25 RCTs were terminated early, predominantly due to poor accrual. … WBRT plus systemic therapy was associated with increased risk for vomiting. … interval [CI], 0.69 to 1.73; 4 RCTs; low strength of evidence [SoE]) or death due to brain metastases (relative … risk [RR], 0.93; CI, 0.48 to 1.81; 3 RCTs; low SoE). … systemic therapy (RR, 1.44; CI, 1.03 to 2.00; 14 studies; moderate SoE) was associated with increased risks

134. Evidence Report on the (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/bundled-payments-quality-effects_research-protocol.pdf
     June 23, 2011 - The evidence of risks (e.g., patient selection) will also be summarized. … Analyzing shifts in economic risks to providers in proposed payment and delivery system reforms. … size that is unlikely to have occurred in the absence of a true effect of the intervention (e.g., relative … risk >5). … effect size that it could have occurred solely as a result of bias from confounding factors (e.g., relative

135. Executive summary_Comparative Effectiveness Review No. 264_Social and Structural Determinants of Maternal Morbidity and Mortality: An Evidence Map (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-264-maternal-morbidity-mortality-executive-summary.pdf
     December 01, 2023 - factors, including biological/medical risk factors … • Limited depth and quality of available research within each risk factor domain— including racism … • Rarely did studies report the excess risk attributable to a specific exposure. … Our focus was studies that attempted to examine pathways underlying risks. … We purposefully focused on studies that examined risk factors that operated interpersonally.

136. Cesarean Section | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/cesarean-section
     January 27, 2016 - Still, it is major surgery and carries risks. … It can raise the risk of having difficulties with future pregnancies. … Archived October 22, 2012 Future Research Needs for Strategies To Reduce Cesarean Birth in Low-Risk … Systematic Review Archived October 22, 2012 Strategies To Reduce Cesarean Birth in Low-Risk

137. Untitled (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hepatitis-c_surveillance.pdf
     December 01, 2015 - Relative risk estimates: 0.89 to 1.2. … Women: No difference in relative risk estimates for SVR •! Blacks vs. … Non-Black patients: No clear difference in relative risk estimates. … Relative risk estimates: 0.89 to 1.2. … Non-Black patients: No clear difference in relative risk estimates.

138. Untitled (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hepatitis-c_surveillance.pdf
     December 01, 2015 - Relative risk estimates: 0.89 to 1.2. … Women: No difference in relative risk estimates for SVR •! Blacks vs. … Non-Black patients: No clear difference in relative risk estimates. … Relative risk estimates: 0.89 to 1.2. … Non-Black patients: No clear difference in relative risk estimates.

139. Comparative Effectiveness of Medications To Reduce Risk of Primary Breast Cancer in Women | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/breast-cancer-medications/research
     December 01, 2019 - Evidence Reports Comparative Effectiveness of Medications To Reduce Risk … SHARE: Comparative Effectiveness of Medications To Reduce Risk … to evaluate the comparative effectiveness of tamoxifen citrate, raloxifene, and tibolone to reduce risk … assess the nature and magnitude of harms, and examine how benefits and harms vary by age, breast cancer risk … Project Timeline Comparative Effectiveness of Medications To Reduce Risk of Primary Breast Cancer in

140. Noninvasive Technologies for the Diagnosis of Coronary Artery Disease in Women: Future Research Needs | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/cad-women-diagnosis-future/research
     December 01, 2019 - AHA suggests there is evidence showing that women at risk for coronary artery disease (CAD) are less … coronary angiography, a procedure that is indicated in patients who have chest pain and are at high risk … Technologies for the Diagnosis of Coronary Artery Disease in Women," evaluated the diagnostic accuracy and risks … Thirteen comparative studies reported risks. … Thus, there was insufficient evidence regarding the comparative risks of various NIT modalities in women