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Total Results: 2,142 records

Showing results for "response".

361. Comparative Effectiveness of Treatment for Hepatitis C in Adults | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/hepatitis-c/research-protocol
     November 30, 2011 - Most notably, sustained virologic response (SVR), commonly defined as a decline in HCV RNA to undetectable … In consideration of factors associated with different response rates, guidelines for treatment suggest … An additional consideration is the variability in sustained viral response (SVR) between different HCV … A sustained virologic response reduces risk of all-cause mortality in patients with hepatitis C. … Sustained virologic response and clinical outcomes in patients with chronic hepatitis C and advanced

362. Disposition of Comments for Progestogens for Prevention of Preterm Birth (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth-disposition-121205.pdf
     September 07, 2012 - productID=1239 Published Online: September 7, 2012 2 Commentator & Affiliation Section Comment Response … productID=1239 Published Online: September 7, 2012 3 Commentator & Affiliation Section Comment Response … productID=1239 Published Online: September 7, 2012 4 Commentator & Affiliation Section Comment Response … productID=1239 Published Online: September 7, 2012 5 Commentator & Affiliation Section Comment Response … productID=1239 Published Online: September 7, 2012 6 Commentator & Affiliation Section Comment Response

363. Drug Therapy for Early Rheumatoid Arthritis: A Systematic Review Update | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/rheumatoid-arthritis-medicine-update/final-report-update-2018
     July 16, 2018 - MTX and tumor necrosis factor (TNF) biologics or non-TNF biologics most likely yield higher treatment response … treatment with MTX monotherapy or any biologic monotherapy (range of American College of Rheumatology response … Network meta-analyses found higher ACR50 response for combination therapy of biologics plus MTX than

364. Topic Coming Back CER 28 DMARDs in Children with JIA NSD _SJ Clean (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_overview.pdf
     March 27, 2014 - and intra-rater reliability, internal reliability, construct validity, responsiveness (standardized response … 4.0 Pediatric Quality of Life Inventory Rheumatology Module (PedsQL-RM) Composite measures of response … therapy and developing definitions of disease status: American College of Rheumatology Pediatric Response

365. Disposition of Comments for CER 160 Binge Eating Disorder (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/binge-eating-disposition-160504.pdf
     December 09, 2015 - Evidence on dose response in this trial was obtained from the peer-reviewed publication (McElroy et … No response required. 27 TEP Reviewer #5 General Comments The target population, audience, and … In response, we have added text regarding the findings of the National Task Force. … We have added the following text in response to the reviewer’s comment: Grades for RCT bodies of … In response, within the Discussion, we added text under “KQ2.

366. Comparative Effectiveness Research Review Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_disposition-comments.pdf
     February 13, 2012 - productID=960 Published Online: February 13, 2012 2 Commentator & Affiliation Section Comment Response … productID=960 Published Online: February 13, 2012 3 Commentator & Affiliation Section Comment Response … productID=960 Published Online: February 13, 2012 4 Commentator & Affiliation Section Comment Response … productID=960 Published Online: February 13, 2012 5 Commentator & Affiliation Section Comment Response … The changes to the text clarifying the patient population made in response to points above also address

367. Disposition of Comments Report for Antinuclear Antibody, Rheumatoid Factor, and Cyclic-Citrullinated Peptide Tests for Evaluating Musculoskeletal Complaints in Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/musculoskeletal-complaints-tests-children_disposition-comments.pdf
     March 07, 2012 - Would suggest that ANA titer be addressed in each Key Question response. … There are also no data presented concerning what is done in response to the test results. … &productID=970 Published Online: March 7, 2012 10 Commentator & Affiliation Section Comment Response … &productID=970 Published Online: March 7, 2012 11 Commentator & Affiliation Section Comment Response … &productID=970 Published Online: March 7, 2012 12 Commentator & Affiliation Section Comment Response

368. Physical Therapy for Knee Pain Secondary to Osteoarthritis Disposition of Comment Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-knee-physical-therapy_disposition-comments.pdf
     November 06, 2012 - productID=1285 Published Online: November 6, 2012 2 Commentator & Affiliation Section Comment Response … productID=1285 Published Online: November 6, 2012 3 Commentator & Affiliation Section Comment Response … productID=1285 Published Online: November 6, 2012 4 Commentator & Affiliation Section Comment Response … productID=1285 Published Online: November 6, 2012 5 Commentator & Affiliation Section Comment Response … They also correctly identify the need for more data on the dose-response for these interventions.

369. Chronic Kidney Disease Stages 1-3: Screening, Monitoring, and Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_disposition-comments.pdf
     August 01, 2012 - displayproduct&productid=809 Published Online: January 2012 2 Commentator & Affiliation Section Comment Response … displayproduct&productid=809 Published Online: January 2012 3 Commentator & Affiliation Section Comment Response … to a posting document (preliminary protocol), and in response to the draft report. … input from these parties, including from stakeholders from the kidney community (e.g., ASN, NKF) in response … productid=809 Published Online: January 2012 43 Commentator & Affiliation Section Comment Response

370. Disposition of Comments for Use of Natriuretic Peptide Measurement in the Management of Heart Failure (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_disposition-comments.pdf
     November 20, 2013 - productID=1754 Published Online: November 20, 2013 Commentator & Affiliation Section Comment Response … =1754 Published Online: November 20, 2013 10 Commentator & Affiliation Section Comment Response … =1754 Published Online: November 20, 2013 11 Commentator & Affiliation Section Comment Response … =1754 Published Online: November 20, 2013 12 Commentator & Affiliation Section Comment Response … =1754 Published Online: November 20, 2013 13 Commentator & Affiliation Section Comment Response

371. Gene Expression Profiling for Predicting Outcomes in Patients With Stage II Colon Cancer | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/colon-cancer-gene-profiling/research-protocol
     March 13, 2012 - expression profiling, may improve the clinician’s ability to assess individualized risk and predict response … Predictive outcomes reflect the rate of response to adjuvant chemotherapy. … Some GEP test results may indicate a patient-specific, preferred regimen (greatest likelihood of response … In addition, this report will collect information on response to adjuvant chemotherapy as another outcome … For response to adjuvant chemotherapy, how was it measured?

372. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
     September 08, 2011 - Cytokines are released non-specifically in response to inflammation and infection, but endotoxins are … outcomes such as changes in patient management, duration of antibiotic therapy, length of stay and response … intermediate out- comes (antibiotic exposure, duration of antibiotic therapy, length of stay, response … 2011 and case series using the search term Procalcitonin (text word) AND “Systemic Inflammatory Response … Procalcitonin versus C-reactive protein as predictive markers of response to antibiotic therapy in

373. Disposition of Comments Report for Cardiac Troponins Used as Diagnostic and Prognostic Tests in Patients Wtih Kidney Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-function_disposition-comments.pdf
     August 11, 2014 - productID=1949 Published Online: August 11, 2014 Commentator & Affiliation Section Comment Response … productID=1949 Published Online: August 11, 2014 2 Commentator & Affiliation Section Comment Response … productID=1949 Published Online: August 11, 2014 3 Commentator & Affiliation Section Comment Response … productID=1949 Published Online: August 11, 2014 4 Commentator & Affiliation Section Comment Response … productID=1949 Published Online: August 11, 2014 5 Commentator & Affiliation Section Comment Response

374. Non-Pharmacologic Interventions for Treatment-resistant Depression in Adults — Research Protocol Document | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/treatment-resistant-depression/research-protocol
     December 09, 2009 - CBT or IPT]) differ in efficacy or effectiveness in treating acute phase depressive symptoms (e.g., response … Note: KQ1 was revised to add this subquestion in response to feedback from our Technical Expert Panel … Comparators: ECT, rTMS, VNS, psychotherapy, pharmacologic treatments Outcomes for each question Response … two key questions pertain to the efficacy and effectiveness of obtaining (KQ1) and maintaining (KQ2) response … KQ3 addresses response and remission for psychiatric subtypes of treatment-resistant depression (e.g.

375. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/treatment-resistant-depression_research-protocol.pdf
     December 09, 2009 - CBT or IPT]) differ in efficacy or effectiveness in treating acute phase depressive symptoms (e.g., response … Note: KQ1 was revised to add this subquestion in response to feedback from our Technical Expert Panel … TRD, do non-pharmacologic interventions differ in their efficacy or effectiveness for maintaining response … ECT, rTMS, VNS, demonstrated effective psychotherapy • Outcomes for each question • Remission • Response … KQ3 addresses response and remission for psychiatric subtypes of treatment-resistant depression (e.g

376. Drug Therapy for Early Rheumatoid Arthritis in Adults – An Update | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/rheumatoid-arthritis-medicine-update/research-protocol
     May 24, 2017 - The EULAR response criteria are defined as shown in Table 2. Table 2. … DAS28 = Disease Activity Score using 28 joints ≤3.2 Good response Moderate response No response … > 3.2 and ≤ 5.1 Moderate response Moderate response No response > 5.1 Moderate response … No response No response Challenges in Treating Early RA Challenges and controversies related to … If we do not receive a response, we will not include the study in question.

377. Technical Brief 16 Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/advanced-care-decision-aids_disposition-comments.pdf
     July 29, 2014 - productID=1938 Published Online: July 29, 2014 2 Commentator & Affiliation Section Comment Response … productID=1938 Published Online: July 29, 2014 3 Commentator & Affiliation Section Comment Response … productID=1938 Published Online: July 29, 2014 4 Commentator & Affiliation Section Comment Response … productID=1938 Published Online: July 29, 2014 5 Commentator & Affiliation Section Comment Response … productID=1938 Published Online: July 29, 2014 6 Commentator & Affiliation Section Comment Response

378. Pneumonia-Antibiotic-Treatment Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
     November 01, 2014 - We looked at benefits defined as both intermediate outcomes (clinical response and use of ventilators … Clinical response or mechanical ventilation? b. Morbidity or mortality? c. … Clinical response or mechanical ventilation? b. Morbidity or mortality? c. … PK/PD Measures for Dosing or Monitoring Evidence was insufficient for clinical response, mechanical … For certain patient-centered outcomes, such as clinical response and treatment failure not otherwise

379. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1512.pdf
     December 29, 2015 - to two or more NSAIDs or patients who have had an inadequate response to a biologic TNF inhibitor … Patients given secukinumab 150 mg had significantly higher ASAS20 response rates than patients given … to two or more NSAIDs or patients who have had an inadequate response to TNF inhibitors. … Patients receiving secukinumab 75, 150, or 300 mg SC had significantly higher ACR20 response rates … After 12 weeks of treatment, patients receiving baricitinib had significantly higher ACR20 response

380. Interventions To Improve Patient Adherence to Hepatitis C Treatment: Comparative Effectiveness | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/hepatitis-c-treatment-adherence/research
     December 20, 2012 - In the eight studies reporting sustained viral response (SVR), two showed a statistically significantly … Conclusions Adherence interventions might improve patient adherence and viral response in patients